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1. 发明申请

US20120330288A1 DEVICE AND METHOD FOR TREATING THE EPIDERMIS 审中-公开
标题翻译：用于治疗EPIDERMIS的装置和方法
公开(公告)号：US20120330288A1
公开(公告)日：2012-12-27
申请号：US13577091
申请日：2010-02-04
申请人： Gabriele Clementi , Leonardo Masotti , Mauro Galli , Nicola Zerbinati
发明人： Gabriele Clementi , Leonardo Masotti , Mauro Galli , Nicola Zerbinati
IPC分类号： A61B18/20 , A61B18/22
CPC分类号： A61B18/20 , A61B18/203 , A61B2018/00452 , A61B2018/0047 , A61B2018/20351 , A61B2018/20355 , A61B2018/20359 , A61B2018/205545
摘要： A laser device is described for skin ablation treatment. The device comprises a laser source (5) and a handpiece (9). The laser beam has a Gaussian distribution of the power density to obtain different effects in the various regions exposed to the laser beam.
摘要翻译：描述了用于皮肤消融治疗的激光装置。该装置包括激光源（5）和手机（9）。激光束具有功率密度的高斯分布，以在暴露于激光束的各个区域中获得不同的效果。

2. 发明申请

US20100292681A1 DEVICE FOR THE USE, ALSO SINGLE USE, OF AN OPTICAL FIBER FOR INVASIVE SURGICAL LASER TREATMENT IN THE HUMAN BODY 审中-公开
标题翻译：使用手段，还可单用一根光纤，用于人体内进行外科手术激光治疗
公开(公告)号：US20100292681A1
公开(公告)日：2010-11-18
申请号：US12681195
申请日：2008-10-03
申请人： Damiano Fortuna , Leonardo Masotti , Andreas Papini
发明人： Damiano Fortuna , Leonardo Masotti , Andreas Papini
IPC分类号： A61B18/22
CPC分类号： A61B18/22 , A61B18/24 , A61B2018/2005 , A61B2018/225 , A61B2018/2261
摘要： The device comprises a distal portion of rigid tube and a proximal portion of flexible tube connected to one another, in which the optical fiber is housed and fixed, the desired useful end of this fiber projecting from said portion of rigid tube; a manoeuvring tubular handpiece is fitted on said portion of rigid tube.
摘要翻译：该装置包括刚性管的远侧部分和彼此连接的柔性管的近端部分，其中光纤被容纳和固定，该光纤的所需有用端从刚性管的所述部分突出; 操纵的管状手持件装配在刚性管的所述部分上。

3. 发明申请

US20100189156A1 RADIO FREQUENCY EXCITED GAS LASER SOURCE 有权
标题翻译：无线电频率激光源激光源
公开(公告)号：US20100189156A1
公开(公告)日：2010-07-29
申请号：US12665476
申请日：2008-06-24
申请人： Gabriele Clementi , Leonardo Masotti , Alberto Severi
发明人： Gabriele Clementi , Leonardo Masotti , Alberto Severi
IPC分类号： H01S3/22 , H01S3/038 , H01S3/0973
CPC分类号： H01S3/038 , H01S3/03 , H01S3/0385 , H01S3/0407 , H01S3/041 , H01S3/0971 , H01S3/2232
摘要： There is described a gas laser comprising a pair of substantially mutually parallel and opposed electrodes (17, 37), between which a volume is defined containing a gas in which said electrodes generate a discharge. At opposed ends of the electrodes, in said volume, mirrors (65) are arranged to define a resonant cavity. The electrodes form an integral part of two portions (5, 7) of a sealed housing (1), containing the gas and in which the mirrors and the electrodes are housed. The two portions (5, 7) forming the housing are electrically
摘要翻译：描述了一种气体激光器，其包括一对基本上相互平行和相对的电极（17,37），在该电极之间限定了体积，其中所述电极产生放电。在电极的相对端，在所述体积中，反射镜（65）被布置成限定谐振腔。电极形成密封壳体（1）的两部分（5,7）的一部分，其包含气体，并且其中容纳反射镜和电极。形成壳体的两个部分（5,7）是电气的

4. 发明申请

US20060277998A1 Method and device for local spectral analysis of an ultrasonic signal 失效
公开(公告)号：US20060277998A1
公开(公告)日：2006-12-14
申请号：US10595336
申请日：2004-10-05
申请人： Leonardo Masotti
发明人： Leonardo Masotti
IPC分类号： G01H13/00
CPC分类号： G01S7/52036 , G01S15/8977
摘要： The method decomposes the radio frequency signal into sub-bands by filtering, for example with a time-frequency transform. From the coefficients acquired through decomposition a matrix of spectral coefficients is obtained, from which local estimators are obtained, constituted in particular by the coefficients of the interpolating polynomials. The statistical distribution of the local estimators is evaluated in windows overlaid on the ultrasound frame. The conformation of the distribution histograms of the spectral coefficients provides a parameter which, combined with the local estimators, provides weighted local estimators, which contain spectral information useful in the identification of specific structures in the organ subjected to ultrasound analysis.

5. 发明申请

US20060224148A1 System and method for laser lipolysis 有权
标题翻译：激光脂解的系统和方法
公开(公告)号：US20060224148A1
公开(公告)日：2006-10-05
申请号：US11099216
申请日：2005-04-05
申请人： George Cho , Leonardo Masotti
发明人： George Cho , Leonardo Masotti
IPC分类号： A61B18/18
CPC分类号： A61B18/22 , A61B2017/00057 , A61B2017/00084 , A61B2018/00005 , A61B2018/2288 , A61B2090/3937 , A61B2562/0276
摘要： A device and related method for the removal of subcutaneous adipose layers comprises a laser source; an optical fiber for conveying a laser beam emitted by the laser source; and a hollow cannula for guiding the fiber to the subcutaneous treatment area. The cannula has a curved portion at its distal end, where the curved portion can be shaped to roughly conform to the contour of the patient's body structure. In this way, laser energy from the fiber, applied to the adipose layers, is generally directed away from the lower dermis of the patient, minimizing the risk of non-reversible damage to the dermis, including skin necrosis. In another embodiment, the optical fiber is a side-firing fiber that directs the laser energy away from the dermis. In other embodiments, a radiation detector, such as a thermal or optical sensor, monitors the temperature at the surface of the skin above the treatment area to warn the operator of harmful temperatures in the lower dermis. In another embodiment, a temperature sensitive material is applied to the surface of the skin above the treatment area to warn of harmful dermal temperatures. In another embodiment, a cooling mechanism cools the surface of the skin above the treatment area to prevent damage to the dermis.
摘要翻译：用于去除皮下脂肪层的装置和相关方法包括激光源; 用于传送由激光源发射的激光束的光纤; 以及用于将纤维引导到皮下治疗区域的中空套管。套管在其远端处具有弯曲部分，其中弯曲部分可以被成形为大致符合患者身体结构的轮廓。以这种方式，施加到脂肪层的来自纤维的激光能量通常远离患者的下部真皮，从而最小化对真皮的不可逆损伤的风险，包括皮肤坏死。在另一个实施例中，光纤是将激光能量远离真皮的侧发光纤。在其他实施例中，放射线检测器（例如热或光学传感器）监测治疗区域上方皮肤表面的温度，以向操作者警告下层真皮中的有害温度。在另一个实施方案中，将感温材料施加到处理区域上方的皮肤表面以警告有害的皮肤温度。在另一个实施例中，冷却机构将治疗区域上方的皮肤表面冷却以防止对真皮的损伤。

6. 发明授权

US5754327A Device and method for deflecting a laser beam by means of a single mirror 失效
标题翻译：用于通过单个反射镜偏转激光束的装置和方法
公开(公告)号：US5754327A
公开(公告)日：1998-05-19
申请号：US797832
申请日：1997-02-10
申请人： Leonardo Masotti , Gabriele Clementi , Angelo Bove
发明人： Leonardo Masotti , Gabriele Clementi , Angelo Bove
IPC分类号： G02B7/182 , G02B26/08
CPC分类号： G02B7/1828
摘要： The device for deflecting a laser beam comprises a mirror (1) and means for orientating the mirror according to a predetermined equation for the controlled deflection of the laser beam (F). The mirror (1) is supported so that it can oscillate about two axes and the means for orientating the mirror comprise a plurality of electromagnets (11A, 11B, 15; 13A, 13B, 17) supplied with currents which are controlled and variable in time (I.sub.15, I.sub.17) to exert magnetic forces on said mirror (3).
摘要翻译：用于偏转激光束的装置包括反射镜（1）和用于根据用于激光束（F）的受控偏转的预定方程来定向反射镜的装置。反射镜（1）被支撑成使得其能够围绕两个轴线摆动，并且用于使反射镜定向的装置包括多个电磁体（11A，11B，15; 13A，13B，17）（I15，I17）在所述反射镜（3）上施加磁力。

7. 发明授权

US5000553A Apparatus for the alignment of a laser beam inside an articulated tubular arm 失效
标题翻译：用于将激光束对准铰接的管状臂内的装置
公开(公告)号：US5000553A
公开(公告)日：1991-03-19
申请号：US467642
申请日：1990-01-19
申请人： Gabriele Clementi , Leonardo Masotti , Francesco Muzzi
发明人： Gabriele Clementi , Leonardo Masotti , Francesco Muzzi
IPC分类号： A61B18/20 , B23K26/08 , B23K26/10 , G02B7/24
CPC分类号： B23K26/0884 , A61B18/201 , G02B7/24
摘要： The articulated arm of a laser equipment comprises at least an articulation with a corresponding mirror in a fixed and non-adjustable position with respect to said articulation. At least one of the sections of the articulated arm converging into said articulation is engaged with the articulation in an angularly adjustable manner. In this way, with an angular adjustment of said arm section a perfect alignment of the laser beam in the tubular arm can be achieved.
摘要翻译：激光设备的铰接臂至少包括与相对于所述关节连接的固定且不可调节位置的相应反射镜的铰接。会聚到所述关节中的关节臂的至少一个部分以角度可调节的方式与关节连接。以这种方式，通过对所述臂部的角度调节，可以实现激光束在管状臂中的完美对准。

8. 发明授权

US10149984B2 Device and method for skin laser treatment 有权
公开(公告)号：US10149984B2
公开(公告)日：2018-12-11
申请号：US13984635
申请日：2012-02-09
申请人： Stefano Modi , Maurizio Scortecci , Damiano Fortuna , Tiziano Zingoni , Leonardo Masotti , Gabriele Clementi , Nicola Zerbinati
发明人： Stefano Modi , Maurizio Scortecci , Damiano Fortuna , Tiziano Zingoni , Leonardo Masotti , Gabriele Clementi , Nicola Zerbinati
IPC分类号： A61N5/06 , A61B18/20 , A61N1/04 , A61N1/06 , A61N1/32 , A61B18/12 , A61B17/00 , A61B18/00 , A61B90/50
摘要： The system for treating a region of the epidermis, comprising: —at least one laser energy source; —a time control device to generate a laser beam; —a laser energy focusing system arranged and produced to direct a laser beam on said region of the epidermis. The control device generates a laser beam comprising a plurality of composite pulses, emitted at a base frequency, each composite pulse comprising a sequence of sub-pulses at a higher frequency than said base frequency.

9. 发明授权

US08113209B2 Sub-dermal laser skin treatment 有权
标题翻译：皮下激光皮肤治疗
公开(公告)号：US08113209B2
公开(公告)日：2012-02-14
申请号：US11704710
申请日：2007-02-09
申请人： Leonardo Masotti , George E. S. Cho
发明人： Leonardo Masotti , George E. S. Cho
IPC分类号： A61B19/00
CPC分类号： A61B18/22 , A61B2017/00057 , A61B2017/00084 , A61B2018/00005 , A61B2018/2288 , A61B2090/3937 , A61B2562/0276
摘要： A method and system for skin tightening comprises a hollow cannula that contains an optical fiber connected to a laser source. The cannula is inserted subcutaneously into a patient so that the end of the fiber is located within the tissue underlying the dermis. The source emits an output pulse that is conveyed by the fiber to the dermis, where the pulse causes collagen destruction and shrinkage within the treatment area. Radiation from the skin surface is detected to prevent non-reversible damage to the dermis, such as skin necrosis and excessive collagen melting. This method of sub-cutaneous laser treatment can also be used to treat striae, or stretch marks.
摘要翻译：用于皮肤紧固的方法和系统包括中空插管，其包含连接到激光源的光纤。将套管皮下插入患者体内，使得纤维的末端位于真皮下面的组织内。源发射由纤维传送到真皮的输出脉冲，其中脉冲导致治疗区域内的胶原蛋白破坏和收缩。检测皮肤表面的辐射以防止对真皮的不可逆损伤，例如皮肤坏死和过度的胶原蛋白熔化。这种亚皮肤激光治疗方法也可用于治疗条纹或妊娠纹。

10. 发明申请

US20110208273A1 DEVICE AND METHOD FOR REGENERATIVE THERAPY BY HIGH INTENSITY LASER THERAPY 有权
标题翻译：通过高强度激光治疗的再生治疗的装置和方法
公开(公告)号：US20110208273A1
公开(公告)日：2011-08-25
申请号：US13048627
申请日：2011-03-15
申请人： Damiano Fortuna , Leonardo Masotti
发明人： Damiano Fortuna , Leonardo Masotti
IPC分类号： A61N5/067
CPC分类号： A61N5/06
摘要： A method of high intensity laser treatment for stimulating regeneration of living biological tissue in a patient by applying a pulsed laser beam to a skin of the patient in need of the treatment.
摘要翻译：一种高强度激光治疗方法，其通过将脉冲激光束施加到需要治疗的患者皮肤上来刺激患者中活体生物组织的再生。

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