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1. 发明申请

US20140336116A1 Glycosylated Polypeptide and Drug Composition Containing Said Polypeptide 有权
标题翻译：糖基化多肽和含有所述多肽的药物组合物
公开(公告)号：US20140336116A1
公开(公告)日：2014-11-13
申请号：US14342359
申请日：2012-09-03
申请人： Hirofumi Ochiai , Taiji Shimoda , Kazuhiro Fukae , Masatoshi Maeda , Kazuyuki Ishii , Kenta Yoshida , Katsunari Tezuka , Keisuke Tazuru
发明人： Hirofumi Ochiai , Taiji Shimoda , Kazuhiro Fukae , Masatoshi Maeda , Kazuyuki Ishii , Kenta Yoshida , Katsunari Tezuka , Keisuke Tazuru
IPC分类号： C07K14/655
CPC分类号： A61K47/64 , A61K38/00 , A61K47/549 , C07K14/6555
摘要： [Problem] To provide a glycosylated polypeptide having an affinity to somatostatin receptors, and, compared to somatostatins, having improved in-blood stability. [Solution] The glycosylated polypeptide is characterized by at least one amino acid in a somatostatin or an analog thereof being replaced with a glycosylated amino acid.
摘要翻译：提供对生长抑素受体具有亲和力的糖基化多肽，以及与促生长激素抑制素相比具有改善的血液内稳定性。 [溶液]糖基化多肽的特征在于生长抑素中的至少一个氨基酸或其类似物被糖基化的氨基酸替代。

2. 发明申请

US20140315800A1 Glycosylated Polypeptide and Drug Composition Containing Said Polypeptide 有权
标题翻译：糖基化多肽和含有所述多肽的药物组合物
公开(公告)号：US20140315800A1
公开(公告)日：2014-10-23
申请号：US14342360
申请日：2012-09-03
申请人： Hirofumi Ochiai , Taiji Shimoda , Kazuhiro Fukae , Masatoshi Maeda , Keisuke Tazuru , Kenta Yoshida
发明人： Hirofumi Ochiai , Taiji Shimoda , Kazuhiro Fukae , Masatoshi Maeda , Keisuke Tazuru , Kenta Yoshida
IPC分类号： C07K14/47
CPC分类号： C07K14/655 , A61K38/00 , A61K47/549 , C07K14/47 , C07K14/6555
摘要： [Problem] To provide a glycosylated polypeptide having affinity to somatostatin receptors and, compared to somatostatins, having improved in-blood stability. [Solution] The glycosylated polypeptide is characterized by at least two amino acids in a somatostatin or an analogue thereof being replaced by glycosylated amino acids.
摘要翻译：提供对生长抑素受体具有亲和力的糖基化多肽，与生长激素类似物具有改善的血液内稳定性。 [溶液]糖基化多肽的特征在于生长抑素中的至少两个氨基酸或其类似物被糖基化的氨基酸替代。

3. 发明授权

US6051677A Gas separating membrane having a polycarbodiimide resin layer 失效
标题翻译：具有聚碳二亚胺树脂层的气体分离膜
公开(公告)号：US6051677A
公开(公告)日：2000-04-18
申请号：US135558
申请日：1998-08-18
申请人： Masatoshi Maeda , Masahiro Yoshioka , Takahiro Fukuoka , Michie Sakamoto , Amane Mochizuki
发明人： Masatoshi Maeda , Masahiro Yoshioka , Takahiro Fukuoka , Michie Sakamoto , Amane Mochizuki
IPC分类号： B01D53/22 , B01D39/16 , B01D69/12 , B01D71/58 , C08G18/02 , C08G18/79 , C08G73/00 , C08G73/10 , B01D39/00
CPC分类号： B01D71/58 , B01D39/16 , C08G73/00 , Y02C10/10 , Y02P20/132 , Y10T428/31504 , Y10T428/31721
摘要： Disclosed is a gas separating membrane comprising a layer made of a polycarbodiimide resin having repeating units represented by formula (I): ##STR1## wherein R represents a divalent organic group. The gas separating membrane available according to the present invention has high permeability and separation selectivity as well as excellent permeating performance, and further has excellent heat resistance, chemical resistance and durability.
摘要翻译：公开了一种气体分离膜，其包含由具有由式（I）表示的重复单元的聚碳二亚胺树脂制成的层：其中R表示二价有机基团。根据本发明可用的气体分离膜具有高渗透性和分离选择性以及优异的渗透性能，并且还具有优异的耐热性，耐化学性和耐久性。

4. 发明授权

US5843351A Highly permeable composite reverse osmosis membrane, method of producing the same 失效
标题翻译：高透性复合反渗透膜，其生产方法
公开(公告)号：US5843351A
公开(公告)日：1998-12-01
申请号：US702383
申请日：1996-08-14
申请人： Masahiko Hirose , Hiroki Ito , Masatoshi Maeda , Kazuo Tanaka
发明人： Masahiko Hirose , Hiroki Ito , Masatoshi Maeda , Kazuo Tanaka
IPC分类号： B01D61/02 , B01D67/00 , B01D69/00 , B01D69/12 , B29D33/48
CPC分类号： B01D67/0088 , B01D61/022 , B01D69/00 , B01D69/12 , B01D69/125
摘要： This invention provides a composite reverse osmosis membrane having a polyamide type skin layer whose average surface roughness is at least 55 nm, and the polyamide type skin layer comprises the reaction product of a compound having amino groups and polyfunctional acid halide compound having acid halide groups. The composite reverse osmosis membrane of this invention is superior in salt rejection and water permeability. A polymer film is formed on a supporting film by contacting a solution containing e.g., m-phenylenediamine with a porous polysulfone supporting film so as to form a layer of the solution on the supporting film, then contacting the film with a solution of trimesic acid chloride and holding the film in a hot air dryer so that a polymer film is formed on the supporting film. The surface of the polyamide type skin layer can also be treated with quaternary ammonium salt and coated with a crosslinked layer of an organic polymer having positively-charged groups. Raw liquid is transmitted from a raw liquid tank to a membrane module for the first stage through a first transmission pump, and the first stage of reverse osmosis treatment is carried out. The composite reverse osmosis membrane coated with the crosslinked layer is used when another reverse osmosis treatment is carried out by using another membrane module for the second stage.
摘要翻译：本发明提供一种具有平均表面粗糙度为55nm以上的聚酰胺型表层的复合反渗透膜，聚酰胺型表皮层包含具有氨基的化合物与具有酰卤基的多官能酰卤化合物的反应产物。本发明的复合反渗透膜的耐盐析性和透水性优异。通过使含有例如间苯二胺的溶液与多孔聚砜负载膜接触，在支持膜上形成聚合物膜，以在支撑膜上形成溶液层，然后将该膜与均苯三甲酸并将膜保持在热空气干燥器中，使得在支撑膜上形成聚合物膜。聚酰胺型表皮层的表面也可以用季铵盐处理，并涂布有具有带正电荷基团的有机聚合物的交联层。原料液体通过第一传动泵从原液槽传送到第一级的膜组件，并进行第一阶段的反渗透处理。当通过使用用于第二阶段的另一个膜组件进行另一个反渗透处理时，使用涂覆有交联层的复合反渗透膜。

5. 发明授权

US5614099A Highly permeable composite reverse osmosis membrane, method of producing the same, and method of using the same 失效
标题翻译：高透性复合反渗透膜及其制造方法及其使用方法
公开(公告)号：US5614099A
公开(公告)日：1997-03-25
申请号：US572900
申请日：1995-12-18
申请人： Masahiko Hirose , Hiroki Ito , Masatoshi Maeda , Kazuo Tanaka
发明人： Masahiko Hirose , Hiroki Ito , Masatoshi Maeda , Kazuo Tanaka
IPC分类号： B01D61/02 , B01D67/00 , B01D69/00 , B01D69/12 , B01D61/00
CPC分类号： B01D67/0088 , B01D61/022 , B01D69/00 , B01D69/12 , B01D69/125
摘要： This invention provides a composite reverse osmosis membrane having a polyamide type skin layer whose average surface roughness is at least 55 nm, and the polyamide type skin layer comprises the reaction product of a compound having amino groups and polyfunctional acid halide compound having acid halide groups. The composite reverse osmosis membrane of this invention is superior in salt rejection and water permeability. A polymer film is formed on a supporting film by contacting a solution containing e.g., m-phenylenediamine with a porous polysulfone supporting film so as to form a layer of the solution on the supporting film, then contacting the film with a solution of trimesic acid chloride and holding the film in a hot air dryer so that a polymer film is formed on the supporting film. The surface of the polyamide type skin layer can also be treated with quaternary ammonium salt and coated with a crosslinked layer of an organic polymer having positively-charged groups. Raw liquid is transmitted from a raw liquid tank to a membrane module for the first stage through a first transmission pump, and the first stage of reverse osmosis treatment is carried out. The composite reverse osmosis membrane coated with the crosslinked layer is used when another reverse osmosis treatment is carried out by using another membrane module for the second stage.
摘要翻译：本发明提供一种具有平均表面粗糙度为55nm以上的聚酰胺型表层的复合反渗透膜，聚酰胺型表皮层包含具有氨基的化合物与具有酰卤基的多官能酰卤化合物的反应产物。本发明的复合反渗透膜的耐盐析性和透水性优异。通过使含有例如间苯二胺的溶液与多孔聚砜负载膜接触，在支撑膜上形成聚合物膜，以在支撑膜上形成溶液层，然后将该膜与均苯三甲酸并将膜保持在热空气干燥器中，使得在支撑膜上形成聚合物膜。聚酰胺型表皮层的表面也可以用季铵盐处理，并涂布有具有带正电荷基团的有机聚合物的交联层。原料液体通过第一传动泵从原液槽传送到第一级的膜组件，并进行第一阶段的反渗透处理。当通过使用用于第二阶段的另一个膜组件进行另一个反渗透处理时，使用涂覆有交联层的复合反渗透膜。

6. 发明授权

US4604999A Inhalator 失效
标题翻译：吸入器
公开(公告)号：US4604999A
公开(公告)日：1986-08-12
申请号：US603427
申请日：1984-04-24
申请人： Masatoshi Maeda
发明人： Masatoshi Maeda
IPC分类号： A61M11/04 , A61M11/06 , A61M15/00
CPC分类号： A61M11/041 , A61M11/065
摘要： An inhalator comprises a water level adjusting chamber which fluidly communicates a water supply chamber and a vaporizing chamber. A manually operable valve interrupts communication between the level adjusting and vaporizing chambers. Upon closing of the valve, a power supply circuit is turned on to energize a heater for heating water in the vaporizing chamber. The interruption of communication between the level adjusting and vaporizing chambers during the use is effective to obtain only a relatively small amount of water to be heated.
摘要翻译：吸入器包括一个水位调节室，该水位调节室使供水室和蒸发室流体连通。手动操作的阀中断液位调节室和蒸发室之间的连通。在关闭阀时，接通电源电路以激励用于加热蒸发室中的水的加热器。在使用期间，水平调节室和蒸发室之间的连通中断对于仅获得相对少量的待加热水是有效的。

7. 发明授权

US4432598A Image reading and recording apparatus and photodeflector therefor 失效
标题翻译：图像读取和记录设备及其光电开关
公开(公告)号：US4432598A
公开(公告)日：1984-02-21
申请号：US265350
申请日：1981-05-19
申请人： Yuichi Akanabe , Hiroaki Ikeda , Masatoshi Maeda , Shinsuke Funaki
发明人： Yuichi Akanabe , Hiroaki Ikeda , Masatoshi Maeda , Shinsuke Funaki
IPC分类号： G02B26/12 , G02B5/09 , G02B27/17
CPC分类号： G02B26/12 , G02B5/09
摘要： A multi-faceted photodeflector includes a plurality of groups of multiple mirrors circumferentially alternating about a rotation axis, each group consisting of the same number of mirrors. Each mirror of any particular one of the mirror groups is inclined, with respect to the rotation axis, at an angle different than the mirrors of all other mirror groups disposed about the rotation axis.
摘要翻译：多面光电偏转器包括围绕旋转轴线周向交替的多组多个反射镜组，每组由相同数量的反射镜组成。任何特定一个镜组的每个反射镜相对于旋转轴线以与围绕旋转轴线布置的所有其它反射镜组的反射镜不同的角度倾斜。

8. 发明授权

US09391236B2 Substrate for optics having a plurality of dot lines, semiconductor light emitting device. and exposure apparatus 有权
标题翻译：具有多个点线的光学用基板，半导体发光装置。和曝光装置
公开(公告)号：US09391236B2
公开(公告)日：2016-07-12
申请号：US14241837
申请日：2012-08-30
申请人： Fujito Yamaguchi , Jun Koike , Masatoshi Maeda
发明人： Fujito Yamaguchi , Jun Koike , Masatoshi Maeda
IPC分类号： H01L33/22 , H01L51/52 , G03F7/00 , G03F7/24 , B29C43/46 , G03F7/20 , B82Y10/00 , B82Y40/00 , H01L33/00 , H01L21/02
CPC分类号： H01L33/22 , B29C43/46 , B29C2043/464 , B82Y10/00 , B82Y40/00 , G03F7/0002 , G03F7/2006 , G03F7/24 , H01L21/0237 , H01L21/0243 , H01L21/02458 , H01L21/0254 , H01L21/02658 , H01L33/007 , H01L51/5268 , Y10T428/24479
摘要： To provide a substrate for optics provided with a fine-structure product which improves luminous efficiency of an LED while improving internal quantum efficiency IQE by decreasing the number of dislocation defects in a semiconductor layer, a substrate for optics (1) is provided with a fine-structure layer (12) including dots comprised of a plurality of convex portions (13) extending in the direction of from the main surface of a substrate (11) to outside the surface, where the fine-structure layer (12) has a plurality of dot lines (13-1 to 13-N) in which a plurality of dots is arranged with a pitch Py in the first direction in the main surface of the substrate (11), while having the plurality of dot lines in which a plurality of dots is arranged with a pitch Px in the second direction orthogonal to the first direction in the main surface of the substrate (11), one of the pitch Py and the pitch Px is a constant interval of nano-order, while the other one is an inconstant interval of nano-order, or both are inconstant intervals of nano-order.
摘要翻译：为了提供具有提供LED的发光效率的精细结构产品的光学基板，同时通过减少半导体层中的位错缺陷数来改善内部量子效率IQE，提供了一种光学元件（1）的基板结构层（12），其包括由从基板（11）的主表面的方向延伸到表面之外的多个凸部（13）的点，其中所述微结构层（12）具有多个其中多个点在衬底（11）的主表面中沿第一方向以间距Py布置的点线（13-1至13-N），同时具有多个点在基板（11）的主表面中，在与第一方向正交的第二方向上的点间距配置有间距Px，间距Py和间距Px之一是纳米级的恒定间隔，而另一方是一个不定期的南方 o阶或两者都是不定期的纳米级间隔。

9. 发明授权

US09263649B2 Layered product for fine pattern formation and method of manufacturing layered product for fine pattern formation 有权
标题翻译：用于精细图案形成的分层产品和用于精细图案形成的分层产品的制造方法
公开(公告)号：US09263649B2
公开(公告)日：2016-02-16
申请号：US14004305
申请日：2012-06-18
申请人： Jun Koike , Fujito Yamaguchi , Masatoshi Maeda , Shinji Arihisa , Masayoshi Arihisa
发明人： Jun Koike , Fujito Yamaguchi , Masatoshi Maeda , Shinji Arihisa
IPC分类号： H01L33/20 , H01L33/58 , H01L21/469 , G03F7/00 , B29C33/38 , B29C33/42 , H01L33/00 , B29C33/40 , B82Y10/00 , B82Y40/00
CPC分类号： H01L33/58 , B29C33/3842 , B29C33/40 , B29C33/424 , B82Y10/00 , B82Y40/00 , G03F7/0002 , H01L21/469 , H01L33/005 , H01L33/20 , H01L2924/0002 , H01L2933/0083 , H01L2924/00
摘要： Disclosed is a layered product for fine pattern formation and a method of manufacturing the layered product for fine pattern formation, capable of easily forming a fine pattern having a thin or no remaining film in order to form a fine pattern having a high aspect ratio on a processing object. The layered product for fine pattern formation (1) of the present invention used to form a fine pattern (220) in a processing object (200) using a first mask layer (103) includes: a mold (101) having a concavo-convex structure (101a) on a surface; and a second mask layer (102) provided on the concavo-convex structure (101a), wherein in the second mask layer (102), a distance (lcc) and a height (h) of the concavo-convex structure (101a) satisfy Formula (1) 0
摘要翻译：公开了用于精细图案形成的层叠产品和用于精细图案形成的层叠产品的制造方法，能够容易地形成具有薄或不残留的薄膜的精细图案，以形成具有高纵横比的精细图案处理对象。用于在使用第一掩模层（103）的处理对象（200）中形成精细图案（220）的本发明的精细图案形成层叠体（1）包括：模具（101），具有凹凸结构（101a）; 以及设置在所述凹凸结构（101a）上的第二掩模层（102），其中在所述第二掩模层（102）中，所述凹凸结构（101a）的距离（lcc）和高度（h）满足式（1）0

10. 发明授权

US09257142B2 Heat-reactive resist material, layered product for thermal lithography using the material, and method of manufacturing a mold using the material and layered product 有权
标题翻译：热反应型抗蚀剂材料，使用该材料的热平版印刷用层压体，以及使用该材料和层叠体制造模具的方法
公开(公告)号：US09257142B2
公开(公告)日：2016-02-09
申请号：US13123854
申请日：2009-10-13
申请人： Yoshimichi Mitamura , Kazuyuki Furuya , Norikiyo Nakagawa , Masatoshi Maeda
发明人： Yoshimichi Mitamura , Kazuyuki Furuya , Norikiyo Nakagawa , Masatoshi Maeda
IPC分类号： G11B7/243 , G11B7/26 , B82Y10/00 , B82Y40/00 , G03F7/00
CPC分类号： G11B7/261 , B82Y10/00 , B82Y40/00 , G03F7/0002 , Y10T428/31504 , Y10T428/31678
摘要： A heat-reactive resist material of the invention is characterized in that the boiling point of the fluoride of the element is 200° C. or more. By this means, it is possible to achieve the heat-reactive resist material having high resistance to dry etching using fluorocarbons to form a pattern with the deep groove depth.
摘要翻译：本发明的热反应型抗蚀剂材料的特征在于，元素的氟化物的沸点为200℃以上。通过这种方式，可以实现使用碳氟化合物具有高抗干蚀刻性的热反应型抗蚀材料，以形成具有深槽深度的图案。

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