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    • 4. 发明申请
    • Anti-Reflux Devices and Methods for Treating Gastro-Esophageal Reflux Disease (GERD)
    • 抗反流装置及治疗胃食管反流病的方法(GERD)
    • US20120089236A1
    • 2012-04-12
    • US12900569
    • 2010-10-08
    • Joseph P. ErricoJohn T. RaffleMichael W. Dudasik
    • Joseph P. ErricoJohn T. RaffleMichael W. Dudasik
    • A61F2/04
    • A61F2/04A61F5/0079A61F2002/044A61F2230/0006A61F2230/0065A61F2230/0067A61F2250/0003A61F2250/0013
    • Devices, systems, and methods for treating gastro-esophageal reflux disease (GERD) include anti-reflux valves and retainers for securing them within the lumen of the esophagus, stomach, or a hiatal hernia. The retainers contain inflatable balloons, some of which may be enveloped by a flexible shell that is used to secure the balloon to tissue. Devices with more than one balloon, a low-profile leaf valve, and a sleeve valve are used to treat reflux in patients with a hiatal hernia. The leaf valve may also be configured for its control by constriction by gastrointestinal lumen muscle, through radial compression of the valve's flange. Bi-directional combination valves are used to treat or diagnose patients with reflux due to transient lower esophageal sphincter relaxations (TLESR). Those valves pass reflux through a channel in which gas and liquid reflux are separated. Methods are described for treating GERD patients who (1) have no hiatal hernia, (2) have a hiatal hernia that is fixed in place, or (3) have a hiatal hernia that slides above and below the diaphragm. Methods are also described for delivering GERD-treatment devices to their target locations within the patient's gastrointestinal tract.
    • 用于治疗胃食管反流病(GERD)的装置,系统和方法包括用于将它们固定在食道,胃或疝气腔内的止回阀和保持器。 保持器包含可充气气囊,其中一些可以被用于将球囊固定到组织的柔性壳包围。 具有多于一个气囊,低角度瓣膜和套管阀的装置用于治疗患有疝气的患者的回流。 瓣膜还可以通过阀的凸缘的径向压缩来配置为通过胃肠腔肌肉的收缩来控制。 双向组合阀用于治疗或诊断由于短暂的食管下括约肌松弛(TLESR)引起的反流患者。 这些阀将回流通过气体和液体回流分离的通道。 描述了治疗GERD患者的方法(1)没有疝气疝,(2)具有固定就位的疝气疝,或(3)在隔膜上方和下方滑动的疝气疝。 还描述了将GERD治疗装置递送到患者胃肠道内的目标位置的方法。