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1. 发明授权

US09725688B2 Bioreactor for syngas fermentation 有权
公开(公告)号：US09725688B2
公开(公告)日：2017-08-08
申请号：US13471873
申请日：2012-05-15
申请人： Peter Simpson Bell , Ching-Whan Ko
发明人： Peter Simpson Bell , Ching-Whan Ko
IPC分类号： C12M1/00 , C12M1/06 , C12N1/00 , C12P7/06 , C12P7/54
CPC分类号： C12M27/02 , B01F3/04262 , B01F7/00641 , B01F7/1675 , B01F7/18 , B01F2003/04326 , C12M21/04 , C12M21/12 , C12M29/04 , C12M29/06 , C12M29/08 , C12M29/18 , C12M29/26 , C12M47/02 , C12N1/20 , C12P7/06 , C12P7/065 , C12P7/54 , Y02E50/17 , Y02E50/343
摘要： A bioreactor is provided that includes a main reactor having a configuration selected from the group consisting of stirred and unstirred tank reactor, trickle bed reactor (TBR), cocurrent contactor (CCC), moving bed bioreactor (MBBR), and a bubble column reactor. The bioreactor also includes a growth reactor continuous with the main reactor and having a configuration selected from the group consisting of stirred and unstirred tank reactor, trickle bed reactor (TBR), cocurrent contactor (CCC), moving bed bioreactor (MBBR), and a bubble column reactor. A method is also provided where acetogenic bacteria are contacted with syngas in a growth fermentor section of a reactor vessel that is continuous with a main fermentor section of a reactor vessel.

2. 发明授权

US09085449B2 Aseptic dosing system 有权
标题翻译：无菌配药系统
公开(公告)号：US09085449B2
公开(公告)日：2015-07-21
申请号：US12719028
申请日：2010-03-08
申请人： James E. Goldman , Hubertus Ulrich Schubert , Peter Simpson , Marcelo Silvado
发明人： James E. Goldman , Hubertus Ulrich Schubert , Peter Simpson , Marcelo Silvado
IPC分类号： B67C3/20 , B65B3/04 , B65B55/12
CPC分类号： B67C3/208 , B65B3/04 , B65B55/12 , B65B2220/14
摘要： The present application provides an aseptic dosing system for dispensing a micro-ingredient. The aseptic dosing system may include a micro-ingredient source adapted to dispense the micro-ingredient, a sterilizer downstream of the micro-ingredient source configured to sterilize the micro-ingredient, and a nozzle downstream of the sterilizer configured to reconstitute the micro-ingredient in or downstream thereof.
摘要翻译：本申请提供了用于分配微量成分的无菌计量系统。无菌剂量系统可以包括适于分配微量成分的微量成分源，微量成分源下游的消毒剂，其构造成对微量成分灭菌;以及灭菌器下游的喷嘴，其配置成重构微量成分在其中或下游。

3. 发明授权

US08921433B2 Process for the conversion of synthesis gas to oxygenates containing C2+ alcohols 有权
标题翻译：将合成气转化为含C2 +醇的含氧化合物的方法
公开(公告)号：US08921433B2
公开(公告)日：2014-12-30
申请号：US11988211
申请日：2006-06-29
申请人： Peter Simpson Bell , Leslie William Bolton , Benjamin Patrick Gracey , Michael Keith Lee
发明人： Peter Simpson Bell , Leslie William Bolton , Benjamin Patrick Gracey , Michael Keith Lee
IPC分类号： C07C27/00 , C07C27/04 , C07C29/151
CPC分类号： C07C29/1518 , C07C29/1516 , C07C31/04 , C07C31/08 , C07C31/10
摘要： Process for the conversion of carbon oxide(s) and hydrogen containing feedstocks into alcohols in the presence of a particulate catalyst.
摘要翻译：在颗粒催化剂存在下将碳氧化物和含氢原料转化成醇的方法。

4. 发明授权

US08586335B2 Process for the production of ethanol and butanol 有权
标题翻译：生产乙醇和丁醇的方法
公开(公告)号：US08586335B2
公开(公告)日：2013-11-19
申请号：US12736101
申请日：2009-02-19
申请人： Peter Simpson Bell , Stephen John Benstead , Neil Turnbull
发明人： Peter Simpson Bell , Stephen John Benstead , Neil Turnbull
IPC分类号： C12P7/40
CPC分类号： C12P7/14 , C12P7/065 , C12P7/08 , C12P7/16 , Y02E50/10 , Y02E50/17
摘要： The present invention relates to a process for the production of ethanol and butanol from biomass, and in particular to a process for the production of ethanol and butanol using two separate fermentation steps, said process comprising: a) passing a biomass feedstock to a first fermentation step, b) in said first fermentation step subjecting the biomass feedstock to anaerobic fermentation at a pH below 6.0 and at a temperature in the range 20 to 700° C. and so as to convert the biomass to a product predominantly comprising acetic acid and butyric acid with at least a 2:1 ratio by weight of acetic acid to butyric acid, c) treating the product stream of step (b) to separate a solution comprising the acetic acid and butyric acid by: (i) separating a solution comprising the acetic acid and butyric acid from any residual solids and (ii) separating bacteria and/or pasteurising or sterilising the solution from the first fermentation step, and d) in a second fermentation step fermenting the solution comprising the acetic acid and butyric acid from step (c) to form ethanol and butanol.
摘要翻译：本发明涉及从生物质生产乙醇和丁醇的方法，特别涉及使用两个单独的发酵步骤生产乙醇和丁醇的方法，所述方法包括：a）将生物质原料送入第一次发酵步骤，b）在所述第一发酵步骤中，使生物质原料进行厌氧发酵，pH低于6.0，温度范围为20至700℃，以便将生物质转化成主要包含乙酸和丁酸的产物酸与乙酸至丁酸的重量比至少为2:1，c）处理步骤（b）的产物流以通过以下方式分离包含乙酸和丁酸的溶液：（i）将包含任何残留固体的乙酸和丁酸，和（ii）从第一发酵步骤分离细菌和/或将溶液灭菌或灭菌，以及d）在第二发酵步骤中发酵包含来自步骤（c）的乙酸和丁酸以形成乙醇和丁醇。

5. 发明申请

US20130252299A1 PROCESS AND APPARATUS FOR THE PRODUCTION OF ALCOHOLS 审中-公开
标题翻译：用于生产醇的方法和装置
公开(公告)号：US20130252299A1
公开(公告)日：2013-09-26
申请号：US13881101
申请日：2011-11-02
申请人： Peter Simpson Bell , Brian Henry Cooke , Neil Turnbull
发明人： Peter Simpson Bell , Brian Henry Cooke , Neil Turnbull
IPC分类号： C12P7/06
CPC分类号： C12P7/065 , C12M21/12 , C12M43/00 , Y02E50/17 , Y02E50/343
摘要： A process for the production of C2− alcohols from a methane-containing feedstock which process comprises a) optionally reacting in a pre-reformer the methane-containing feedstock in the presence of steam, where the steam plus C02 to methane molar ratio is less than 5:1; b) reforming at least a portion of the methane-containing feedstock in a first reformer optionally in the presence of steam, where the steam plus C02 to methane molar ratio is less than 5:1 to produce a first product stream comprising CO, H2 and C02; c) optionally subjecting at least a portion of the first product stream and/or a portion of the methane containing feedstock to a reforming process in a second reformer in the presence of steam and oxygen to produce a second product stream comprising CO, H2 and C02 d) subjecting the product streams to a bacterial fermentation process in a fermenter to produce a third product stream comprising an aqueous solution of at least one C2− alcohol, nutrients and reaction intermediates and a fourth product stream comprising CO, H2 and C02 at least 60% of the CO being converted; e) recycling at least a portion of the fourth product stream to the methane-containing feedstock; f) recovering at least a part of the at least one C2− alcohols from the third product stream to leave a fifth product stream; and g) recycling at least a part of the fifth product stream to the fermenter.
摘要翻译：一种从含甲烷原料生产C2-醇的方法，该方法包括：a）在蒸汽存在下，任选地在预重整器中反应含甲烷的原料，其中蒸汽加CO 2与甲烷的摩尔比小于 5：1; b）任选地在蒸汽存在下任选地在第一重整器中重整至少一部分含甲烷原料，其中蒸汽加CO 2与甲烷的摩尔比小于5:1，以产生包含CO，H 2和 C02; c）在蒸汽和氧气的存在下，任选地使至少一部分第一产物流和/或含甲烷原料的一部分在第二重整器中进行重整过程，以产生包含CO，H 2和CO 2的第二产物流 d）使产物流在发酵罐中进行细菌发酵过程，以产生包含至少一种C 2醇，营养物和反应中间体的水溶液的第三产物流和包含CO，H 2和CO 2的第四产物流至少60 CO转化率的百分比; e）将第四产物流的至少一部分再循环到含甲烷的原料中; f）从第三产物流中回收至少一部分至少一种C 2醇以留下第五产物流; 和g）将第五产物流的至少一部分再循环到发酵罐中。

6. 发明申请

US20130224808A1 PROCESS AND APPARATUS FOR PRODUCING ETHYLENE VIA PREPARATION OF SYNGAS 审中-公开
标题翻译：通过制备乙烯制备乙烯的方法和装置
公开(公告)号：US20130224808A1
公开(公告)日：2013-08-29
申请号：US13881126
申请日：2011-11-02
申请人： Peter Simpson Bell , Graeme Alexander Parker , Neil Turnbull , Vaughn Clifford Williams
发明人： Peter Simpson Bell , Graeme Alexander Parker , Neil Turnbull , Vaughn Clifford Williams
IPC分类号： C12P5/02
CPC分类号： C12P5/026 , C07C1/24 , C12M21/12 , C12M43/02 , C12P7/065 , Y02E50/17 , Y02E50/343 , C07C11/04
摘要： A process for producing ethylene from a carbonaceous containing feedstock the process comprising the steps of a) reforming the carbonaceous containing feedstock into a first product stream comprising carbon dioxide, carbon monoxide and hydrogen; b) fermenting the first product stream with an acetogenic anaerobic bacteria to produce a second product stream comprising ethanol; c) concentrating ethanol from the second product stream into a third product stream and; d) dehydrating ethanol in the third product stream to produce ethylene.
摘要翻译：一种从含碳原料生产乙烯的方法，该方法包括以下步骤：a）将含碳原料重整成包含二氧化碳，一氧化碳和氢的第一产物流; b）用产乙酸厌氧细菌发酵第一产物流以产生包含乙醇的第二产物流; c）将来自第二产物流的乙醇浓缩成第三产物流; d）使第三产物流中的乙醇脱水以产生乙烯。

7. 发明申请

US20120315822A1 Figure and a Composition for Forming the Figure 审中-公开
标题翻译：图和形成图的组合物
公开(公告)号：US20120315822A1
公开(公告)日：2012-12-13
申请号：US13552997
申请日：2012-07-19
申请人： Jason KROSKRITY , Yuk Ha MO , Peter SIMPSON , Sean P. WHITLEY
发明人： Jason KROSKRITY , Yuk Ha MO , Peter SIMPSON , Sean P. WHITLEY
IPC分类号： A63H3/36
CPC分类号： A63H9/00 , A63H3/00
摘要： A toy figure having at least one solid, molded part with a varying thickness is disclosed. The toy figure is a collector or fashion doll that has particular characteristics or properties. The toy figure is formed using a composition of ABS and barium sulfate, which provides several desired characteristics, including at least the aesthetics, feel, weight, and paintability of the toy figure.
摘要翻译：公开了具有至少一个具有变化厚度的固体模制部件的玩具图形。玩具人物是具有特定特征或特性的收集器或时尚娃娃。玩具图形使用ABS和硫酸钡的组合物形成，其提供几个期望的特征，其至少包括玩具图形的美观性，手感，重量和可涂色性。

8. 发明授权

US07831287B2 Dual electrode system for a continuous analyte sensor 有权
标题翻译：用于连续分析物传感器的双电极系统
公开(公告)号：US07831287B2
公开(公告)日：2010-11-09
申请号：US12111062
申请日：2008-04-28
申请人： Mark Brister , James R. Petisce , Peter Simpson
发明人： Mark Brister , James R. Petisce , Peter Simpson
IPC分类号： A61B5/00
CPC分类号： A61B5/14532 , A61B5/14865 , A61B5/1495 , A61B2560/0223
摘要： Disclosed herein are systems and methods for a continuous analyte sensor, such as a continuous glucose sensor. One such system utilizes first and second working electrodes to measure additional analyte or non-analyte related signal. Such measurements may provide a background and/or sensitivity measurement(s) for use in processing sensor data and may be used to trigger events such as digital filtering of data or suspending display of data.
摘要翻译：本文公开了用于连续分析物传感器（例如连续葡萄糖传感器）的系统和方法。一个这样的系统利用第一和第二工作电极来测量附加分析物或非分析物相关信号。这样的测量可以提供用于处理传感器数据的背景和/或灵敏度测量，并且可以用于触发诸如数据的数字滤波或暂停显示数据的事件。

9. 发明申请

US20090192155A1 Identification of Compounds Suitable for Treating Ad 审中-公开
标题翻译：鉴定适用于治疗广告的化合物
公开(公告)号：US20090192155A1
公开(公告)日：2009-07-30
申请号：US12223360
申请日：2007-01-30
申请人： Ian Churcher , Peter Hunt , Carmel Nanthakumar , Peter Simpson
发明人： Ian Churcher , Peter Hunt , Carmel Nanthakumar , Peter Simpson
IPC分类号： A61K31/5377 , C12Q1/48 , A61K31/496 , A61P25/28
CPC分类号： G01N33/6896 , A61K31/40 , C12Q1/485 , G01N2500/00 , G01N2800/2821
摘要： The invention provides a method of screening for compounds which inhibit the hyperphosphorylation of tau, and hence are suitable for treating AD and related conditions.
摘要翻译：本发明提供一种筛选抑制tau高度磷酸化的化合物的方法，因此适用于治疗AD和相关病症。

10. 发明申请

US20080119706A1 Analyte sensor 有权
公开(公告)号：US20080119706A1
公开(公告)日：2008-05-22
申请号：US11543404
申请日：2006-10-04
申请人： Mark Brister , Peter Simpson
发明人： Mark Brister , Peter Simpson
IPC分类号： A61B5/00
CPC分类号： A61B5/14532 , A61B5/14542 , A61B5/14546 , A61B5/1473 , A61B5/14865 , A61B5/1495 , A61B5/412 , A61B5/6848 , A61B5/6849 , A61B2560/0223 , A61M5/14 , A61M5/16804 , A61M5/1723 , A61M2230/201
摘要： Systems and methods of use for continuous analyte measurement of a host's vascular system are provided. In some embodiments, a continuous glucose measurement system includes a vascular access device, a sensor and sensor electronics, the system being configured for insertion into a host's peripheral vein or artery.

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