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1. 发明授权

US08392353B2 Computerized knowledge representation system with flexible user entry fields 有权
标题翻译：具有灵活用户输入字段的计算机化知识表示系统
公开(公告)号：US08392353B2
公开(公告)日：2013-03-05
申请号：US12499761
申请日：2009-07-08
申请人： Raymond J. Cho , Richard O. Chen , Ramon M. Felciano , Daniel R. Richards
发明人： Raymond J. Cho , Richard O. Chen , Ramon M. Felciano , Daniel R. Richards
IPC分类号： G06F17/00 , G06N5/04
CPC分类号： G06N5/022 , G06F17/30734 , Y10S707/99945 , Y10S707/99948
摘要： Methods for constructing and maintaining knowledge representation systems (KRS) are disclosed. The KRS is initially organized and populated using knowledge engineers. After initial organization, scientific domain experts digest and structure source texts for direct entry into the KRS using templates. These templates constrain both the form and content of the digested information, allowing it to be entered directly into the KRS. The methods disclosed herein permit the construction and maintenance of a much larger KRS than could be constructed and maintained using known methods. Fact type specific fact templates are completed, accepting predefined fact types found in predetermined information sources. Fact template may comprise a user interface that constrains user entry to one of a predetermined set of valid entries. The user interface may include a user field that permits entry of new information not included in the predetermined set of valid user entries.
摘要翻译：披露了构建和维护知识表示系统（KRS）的方法。 KRS最初是使用知识工程师组织和填充的。初步组织后，科学领域专家将使用模板简化和构建源文本，直接进入KRS。这些模板限制了消化信息的形式和内容，允许将其直接输入KRS。本文公开的方法允许构建和维护比使用已知方法构建和维护的更大的KRS。事实类型特定事实模板已完成，接受在预定信息源中发现的预定义事实类型。事实模板可以包括限制用户输入到预定的一组有效条目之一的用户界面。用户界面可以包括允许输入未包括在预定的有效用户条目集合中的新信息的用户字段。

2. 发明授权

US06741986B2 Method and system for performing information extraction and quality control for a knowledgebase 有权
标题翻译：为知识库执行信息提取和质量控制的方法和系统
公开(公告)号：US06741986B2
公开(公告)日：2004-05-25
申请号：US10038197
申请日：2001-11-09
申请人： Raymond J. Cho , Richard O. Chen , Ramon M. Felciano , Daniel R. Richards , Philippa Norman
发明人： Raymond J. Cho , Richard O. Chen , Ramon M. Felciano , Daniel R. Richards , Philippa Norman
IPC分类号： G06F1730
CPC分类号： G06F17/30734 , G06F17/30705 , Y10S707/918 , Y10S707/99933 , Y10S707/99935 , Y10S707/99936 , Y10S707/99942
摘要： A system and method of information extraction and storage extracts information from a plurality of articles in a distributed manner and stores the extracted information in an information store. In one embodiment, the system includes identification of a plurality of articles from which information is to be extracted and a plurality of information extractors for extracting the information from the articles. A database is provided for storing information related to the plurality of articles and the plurality of information extractors. The plurality of articles are assigned to the plurality of information extractors for information extraction and the extracted information is then stored in the information store.
摘要翻译：信息提取和存储的系统和方法以分布式方式从多个物品中提取信息，并将提取的信息存储在信息存储器中。在一个实施例中，系统包括要从中提取信息的多个物品的标识和用于从物品中提取信息的多个信息提取器。提供了一种用于存储与多个文章和多个信息提取器有关的信息的数据库。将多个物品分配给多个用于信息提取的信息提取器，然后将所提取的信息存储在信息存储器中。

3. 发明授权

US08793073B2 Drug discovery methods 有权
标题翻译：药物发现方法
公开(公告)号：US08793073B2
公开(公告)日：2014-07-29
申请号：US10632099
申请日：2003-08-01
申请人： Richard O. Chen , Raymond J. Cho , Ramon M. Felciano , Brett Holley , Viresh Patel , Daniel R. Richards , Sushma Selvarajan , Keith Steward , Sara Tanenbaum Schneider
发明人： Richard O. Chen , Raymond J. Cho , Ramon M. Felciano , Brett Holley , Viresh Patel , Daniel R. Richards , Sushma Selvarajan , Keith Steward , Sara Tanenbaum Schneider
IPC分类号： G06F19/10 , G06F19/00 , C12Q1/68
CPC分类号： C40B30/02 , G06F19/12 , G06F19/20 , G06F19/22
摘要： Methods for identifying disease-related pathways that can be used to identify drug discovery targets, to identify new uses for known drugs, to identify markers for drug response, and related purposes.
摘要翻译：用于鉴定可用于鉴定药物发现靶标的疾病相关途径的方法，鉴定已知药物的新用途，鉴定药物反应的标志物和相关目的。

4. 发明授权

US08489334B2 Drug discovery methods 有权
标题翻译：药物发现方法
公开(公告)号：US08489334B2
公开(公告)日：2013-07-16
申请号：US10502420
申请日：2003-02-03
申请人： Richard O. Chen , Raymond J. Cho , Ramon M. Felciano , Bret Holley , Viresh Patel , Daniel R. Richards , Sushma Selvarajan , Keith Steward , Sara Schneider
发明人： Richard O. Chen , Raymond J. Cho , Ramon M. Felciano , Bret Holley , Viresh Patel , Daniel R. Richards , Sushma Selvarajan , Keith Steward , Sara Schneider
IPC分类号： G06F19/10 , G06F19/00
CPC分类号： G06F19/18 , G06F19/12 , G06F19/20 , G06F19/24 , G06F19/26 , G06F19/28
摘要： Method for identifying disease-related pathways that can used to identify discovery targets, to identify new uses for known drugs, to identify markers for drug response, and related purposes.
摘要翻译：用于鉴定可用于鉴定发现靶标的疾病相关途径的方法，识别已知药物的新用途，鉴定药物反应的标志物和相关目的。

5. 发明授权

US07650339B2 Techniques for facilitating information acquisition and storage 有权
标题翻译：促进信息采集和存储的技术
公开(公告)号：US07650339B2
公开(公告)日：2010-01-19
申请号：US10864163
申请日：2004-06-08
申请人： Raymond J. Cho , Richard O. Chen , Ramon M. Felciano , Daniel R. Richards , Philippa Norman
发明人： Raymond J. Cho , Richard O. Chen , Ramon M. Felciano , Daniel R. Richards , Philippa Norman
IPC分类号： G06F17/30
CPC分类号： G06F17/30616 , Y10S707/959 , Y10S707/99933 , Y10S707/99936 , Y10S707/99943
摘要： A method, system, and computer program product are provided for extracting information from a plurality of articles in a distributed manner and for storing the extracted information in an information store. The invention identifies a plurality of articles from which information is to be extracted and a plurality of information extractors for extracting the information from the articles. Each article is assigned a priority score and ranking the articles from highest to lowest priority, thereby generating a queue; wherein the priority score for each article is calculated using a user-configurable priority calculation algorithm. The plurality of articles is assigned to the plurality of information extractors based on order in the queue, wherein an article with a higher rank is presented for information extraction before an article with a lower rank. Information extracted by information extractors from the articles is stored in the information store.
摘要翻译：提供了一种方法，系统和计算机程序产品，用于以分布式方式从多个物品中提取信息，并将所提取的信息存储在信息存储区中。本发明识别要提取信息的多个物品和用于从物品中提取信息的多个信息提取器。每篇文章都被分配一个优先级分数，并将文章从最高优先级排列到最低优先级，从而生成队列; 其中使用用户可配置的优先级计算算法来计算每个物品的优先级得分。基于队列中的顺序将多个物品分配给多个信息提取器，其中在具有较低等级的物品之前呈现具有较高等级的物品用于信息提取。由信息提取器从物品中提取的信息存储在信息存储器中。

6. 发明授权

US07577683B2 Methods for the construction and maintenance of a knowledge representation system 有权
标题翻译：建立和维护计算机化知识表现系统的方法
公开(公告)号：US07577683B2
公开(公告)日：2009-08-18
申请号：US10770864
申请日：2004-02-02
申请人： Raymond J. Cho , Richard O. Chen , Ramon M. Felciano , Daniel R. Richards
发明人： Raymond J. Cho , Richard O. Chen , Ramon M. Felciano , Daniel R. Richards
IPC分类号： G06F17/30
CPC分类号： G06N5/022 , G06F17/30734 , Y10S707/99945 , Y10S707/99948
摘要： Methods for constructing and maintaining knowledge representation systems are disclosed herein. The knowledge representation system is initially organized and populated using knowledge engineers. After the initial organization, scientific domain experts digest and structure source texts for direct entry into the knowledge representation system using templates created by the knowledge engineers. These templates constrain both the form and content of the digested information, allowing it to be entered directly into the knowledge representation system. Although knowledge engineers are available to evaluate and dispose of those instances when the digested information cannot be entered in the form required by the templates, their role is much reduced from conventional knowledge representation system construction methods. The methods disclosed herein permit the construction and maintenance of a much larger knowledge representation system than could be constructed and maintained using known methods.
摘要翻译：本文公开了构建和维护知识表示系统的方法。知识表达系统最初是使用知识工程师组织和填充的。在初始组织之后，科学领域专家消化和构建源文本，以便使用由知识工程师创建的模板直接进入知识表示系统。这些模板限制了消化信息的形式和内容，使其能够直接输入到知识表示系统中。虽然知识工程师可以评估和处理这些实例，当消化的信息不能以模板所需的形式输入时，它们的作用从传统知识表示系统构建方法中大大减少。这里公开的方法允许构建和维护比可以使用已知方法构建和维护的更大的知识表示系统。

7. 发明申请

US20110191286A1 Method And System For Performing Information Extraction And Quality Control For A Knowledge Base 审中-公开
标题翻译：知识库执行信息提取和质量控制的方法与系统
公开(公告)号：US20110191286A1
公开(公告)日：2011-08-04
申请号：US13029089
申请日：2011-02-16
申请人： Raymond J. Cho , Richard O. Chen , Ramon M. Felciano , Daniel R. Richards , Philippa Norman
发明人： Raymond J. Cho , Richard O. Chen , Ramon M. Felciano , Daniel R. Richards , Philippa Norman
IPC分类号： G06F17/30
CPC分类号： G06F16/367 , G06F16/35 , Y10S707/918 , Y10S707/99933 , Y10S707/99935 , Y10S707/99936 , Y10S707/99942
摘要： The present invention relates to the field of information extraction and storage id more specifically to techniques for extracting information from a plurality of articles in a distributed manner and for storing the extracted information in an information store an embodiment of the present invention identifies a plurality of articles from which information to be extracted and a plurality of information extractors for extracting the information from e articles. A database is provided for storing information related to the plurality of articles and the plurality of information extractors. The plurality of articles are assigned to the plurality of information extractors for information extraction. Information extracted by formation extractors from the articles is stored in the information store.
摘要翻译：本发明涉及信息提取和存储领域，更具体地涉及以分布式方式从多个商品中提取信息并将所提取的信息存储在信息存储器中的技术，本发明的一个实施例识别出多个商品从其中提取的信息和用于从e文件中提取信息的多个信息提取器。提供了一种用于存储与多个文章和多个信息提取器有关的信息的数据库。多个物品被分配给多个用于信息提取的信息提取器。由物品提取器提取的信息存储在信息存储区中。

8. 发明申请

US20100010957A1 Methods for the Construction and Maintenance of a Computerized Knowledge Representation System 有权
标题翻译：计算机知识表征系统的构建与维护方法
公开(公告)号：US20100010957A1
公开(公告)日：2010-01-14
申请号：US12499761
申请日：2009-07-08
申请人： Raymond J. Cho , Richard O. Chen , Ramon M. Felciano , Daniel R. Richards
发明人： Raymond J. Cho , Richard O. Chen , Ramon M. Felciano , Daniel R. Richards
IPC分类号： G06N5/02
CPC分类号： G06N5/022 , G06F17/30734 , Y10S707/99945 , Y10S707/99948
摘要： Methods for constructing and maintaining knowledge representation systems are disclosed herein. The knowledge representation system is initially organized and populated using knowledge engineers. After the initial organization, scientific domain experts digest and structure source texts for direct entry into the knowledge representation system using templates created by the knowledge engineers. These templates constrain both the form and content of the digested information, allowing it to be entered directly into the knowledge representation system. Although knowledge engineers are available to evaluate and dispose of those instances when the digested information cannot be entered in the form required by the templates, their role is much reduced from conventional knowledge representation system construction methods. The methods disclosed herein permit the construction and maintenance of a much larger knowledge representation system than could be constructed and maintained using known methods.
摘要翻译：本文公开了构建和维护知识表示系统的方法。知识表达系统最初是使用知识工程师组织和填充的。在初始组织之后，科学领域专家消化和构建源文本，以便使用由知识工程师创建的模板直接进入知识表示系统。这些模板限制了消化信息的形式和内容，使其能够直接输入到知识表示系统中。虽然知识工程师可以评估和处理这些实例，当消化的信息不能以模板所需的形式输入时，它们的作用从传统知识表示系统构建方法中大大减少。这里公开的方法允许构建和维护比可以使用已知方法构建和维护的更大的知识表示系统。

9. 发明授权

US06772160B2 Techniques for facilitating information acquisition and storage 有权
标题翻译：促进信息采集和存储的技术
公开(公告)号：US06772160B2
公开(公告)日：2004-08-03
申请号：US09733495
申请日：2000-12-08
申请人： Raymond J. Cho , Richard O. Chen , Ramon M. Felciano , Daniel R. Richards , Philippa Norman
发明人： Raymond J. Cho , Richard O. Chen , Ramon M. Felciano , Daniel R. Richards , Philippa Norman
IPC分类号： G06F1730
CPC分类号： G06F17/30616 , Y10S707/959 , Y10S707/99933 , Y10S707/99936 , Y10S707/99943
摘要： The method and system for extracting information from a plurality of articles and for storing the extracted information in a knowledge-based information store. The method and system identify a plurality of articles from which information is to be extracted. The method and system identify and assign a plurality of information extractors for extracting information from the plurality of articles. The method and system receive information extracted by an information extractor from an article assigned to the information extractor. The method and system enable a content reviewer to review the extracted information received from the information extractor and the content reviewer identifies errors associated with the extracted information. If the error count is above the threshold level, the article may be reassigned for information extraction. If the error count is equal to or below the threshold level, the content reviewer may change the extracted information to correct the errors.
摘要翻译：用于从多个物品中提取信息并将提取的信息存储在基于知识的信息存储中的方法和系统。该方法和系统识别要从中提取信息的多个物品。所述方法和系统识别并分配用于从所述多个物品中提取信息的多个信息提取器。方法和系统从分配给信息提取器的文章中接收由信息提取器提取的信息。所述方法和系统使得内容审阅者能够检查从所述信息提取器接收到的所提取的信息，并且所述内容审阅者识别与所提取的信息相关联的错误。如果错误计数高于阈值级别，则可以重新分配文章以进行信息提取。如果错误计数等于或低于阈值水平，则内容审阅者可以改变所提取的信息以校正错误。

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