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1. 发明授权

US07946992B2 Velocity measuring method and velocity measuring device using the same 失效
标题翻译：速度测量方法和使用其的速度测量装置
公开(公告)号：US07946992B2
公开(公告)日：2011-05-24
申请号：US11915625
申请日：2006-01-06
申请人： Shinichiro Umemura , Takashi Azuma , Tetsuya Hayashi , Naoyuki Murayama
发明人： Shinichiro Umemura , Takashi Azuma , Tetsuya Hayashi , Naoyuki Murayama
IPC分类号： A61B8/00
CPC分类号： G01S15/8981 , A61B8/06 , A61B8/488 , G01S15/8977
摘要： The present invention is to provide a velocity measuring method and a velocity measuring device for carrying out the method. The velocity measuring method includes: a step (S4) for expanding N time series signals by using 0-th to (N−1)-th degree discrete Legendre function as a base; a step (S5) for calculating 2n-th degree complex expansion coefficient by multiplying a linear combination of a (2n−1)-th degree expansion coefficient and a ( 2n+1)-th degree expansion coefficient by an imaginary unit and then linearly combining the result and a 2n-th degree expansion coefficient, and calculating a (2n+1)-th degree complex expansion coefficient by multiplying the (2n+1)-th degree expansion coefficient by an imaginary unit and then linearly combining the result, the 2n-th degree expansion coefficient and a (2n+2)-th degree expansion coefficient; a degree decision step (S4) for determining the degree m of a coefficient having the maximum absolute value among the complex expansion coefficients; and a step (S8) for calculating a signed velocity signal concerning a moving reflection object from a ratio of square sums of the expansion coefficients or complex expansion coefficients corresponding to the degree m.
摘要翻译：本发明提供一种用于实施该方法的速度测量方法和速度测量装置。速度测量方法包括：通过使用第0到第（N-1）度离散勒让德函数作为基础来扩展N个时间序列信号的步骤（S4）通过将第（2n-1）个膨胀系数和第（2n + 1）次膨胀系数的线性组合乘以虚数单位然后线性地计算2n倍复数膨胀系数的步骤（S5）组合结果和2n度膨胀系数，并且通过将第（2n + 1）度膨胀系数乘以虚数单位然后将结果线性组合来计算第（2n + 1）度复数膨胀系数，第2n度膨胀系数和第（2n + 2）膨胀系数; 用于确定复数展开系数中具有最大绝对值的系数的程度m的度决定步骤（S4）以及用于根据与度数m对应的展开系数或复扩展系数的平方和的比率来计算关于移动反射物体的有符号速度信号的步骤（S8）。

2. 发明授权

US07616981B2 Inspection apparatus using nuclear magnetic resonance 失效
标题翻译：使用核磁共振的检查装置
公开(公告)号：US07616981B2
公开(公告)日：2009-11-10
申请号：US10614019
申请日：2003-07-08
申请人： Yo Taniguchi , Hisaaki Ochi , Shinichiro Umemura
发明人： Yo Taniguchi , Hisaaki Ochi , Shinichiro Umemura
IPC分类号： A61B5/05
CPC分类号： G01R33/5676 , G01R33/56509
摘要： There is provided an inspection apparatus using nuclear magnetic resonance which can execute multi-slice and multi-frame cardiac imaging of a heart without giving any load on a subject. An inspection apparatus using nuclear magnetic resonance has static magnetic field generation means generating a static magnetic field; magnetic field gradient generation means generating a magnetic field gradient in a first, a second and a third directions orthogonal to each other; radiofrequency magnetic field generation means generating a radiofrequency magnetic field; signal detection means detecting a nuclear magnetic resonance signal (echo) produced from a subject; arithmetic processing means performing arithmetic processing of the detected nuclear magnetic resonance signal; and control means controlling the magnetic field gradient generation means and the radiofrequency magnetic field generation means, wherein the control means executes a pulse sequence acquiring a projection to determine a similarity coefficient between the projection and a reference projection, thereby detecting respiratory motion of the subject.
摘要翻译：提供了使用核磁共振的检查装置，其可以执行心脏的多层和多帧心脏成像，而不对受试者施加任何负担。使用核磁共振的检查装置具有产生静磁场的静磁场产生装置; 磁场梯度产生装置，在彼此正交的第一，第二和第三方向上产生磁场梯度; 产生射频磁场的射频磁场产生装置; 信号检测装置，用于检测从受检者产生的核磁共振信号（回波）; 算术处理装置执行所检测的核磁共振信号的运算处理; 以及控制装置，其控制磁场梯度产生装置和射频磁场产生装置，其中控制装置执行获取投影的脉冲序列，以确定投影和参考投影之间的相似系数，从而检测被摄体的呼吸运动。

3. 发明授权

US06383140B1 Ultrasonic diagnosis device 有权
标题翻译：超声诊断装置
公开(公告)号：US06383140B1
公开(公告)日：2002-05-07
申请号：US09555044
申请日：2000-05-24
申请人： Yuichi Miwa , Ryuichi Shinomura , Shinichiro Umemura
发明人： Yuichi Miwa , Ryuichi Shinomura , Shinichiro Umemura
IPC分类号： A61B800
CPC分类号： G01S7/52092 , G01S7/52026 , G01S7/52034 , G01S7/52046
摘要： This invention provides a technology that freely changes the frequency of a reference signal in a digital ultrasonic diagnosis device and makes it possible to conduct various high-quality or high-speed imaging. Reception signals obtained by an ultrasonic element group disposed in an array are digitized in a sampling cycle higher than a Nyquist frequency of the reception signals, and are mixed with reference signal. The mixed signals are then accumulated in a sampling direction, a number of the mixed signals accumulated being equal to a number of a plurality of samples, and are delayed and added by wave reception focusing means. The reference signal serially read out and used from memory means in such a manner as to correspond to the sampling number of the reception signals. A reference signal train acquired from signals, the frequency of which decreases gradually with a lapse of time, from wave transmission, or a reference signal train obtained alternately from two signals having different frequencies, may be stored in advance in memory means.
摘要翻译：本发明提供了一种在数字超声波诊断装置中自由地改变参考信号的频率的技术，并且可以进行各种高质量或高速成像。由阵列中布置的超声波元件组获得的接收信号被数字化在比接收信号的奈奎斯特频率高的采样周期中，与参考信号混合。然后，混合信号以采样方向累积，累积的混合信号的数量等于多个采样的数量，并被波接收聚焦装置延迟和相加。参考信号以与接收信号的采样数对应的方式从存储器装置串行读出并使用。可以从存储装置中预先存储从频率从具有不同频率的两个信号交替地从波发送或参考信号序列中逐渐减小的频率的信号获取的参考信号序列。

4. 发明授权

US5458761A Method for analyzing nucleic acid or protein and apparatus therefor 失效
标题翻译：分析核酸或蛋白质的方法及其设备
公开(公告)号：US5458761A
公开(公告)日：1995-10-17
申请号：US378973
申请日：1995-01-27
申请人： Masao Kamahori , Takeshi Fujita , Shinichiro Umemura , Takashi Yamada
发明人： Masao Kamahori , Takeshi Fujita , Shinichiro Umemura , Takashi Yamada
IPC分类号： G01N27/447 , G01N27/26
CPC分类号： G01N27/44704 , G01N27/44721 , G01N27/44743
摘要： Analysis of a nucleic acid samples having thousands of bases is conducted by capillary electrophoresis. The electrophoretic section is provided with a first capillary filled with an agarose gel and a second capillary filled with a polyacrylamide gel. An on-column detector is incorporated with the second capillary for optical detection. To fill a capillary with a gel, a solution is fed under high pressure from a first flow channel through a switching valve into a second flow channel connected to the capillary. To inject a sample in the capillary, a sample injector is connected to a switching valve passage, and a buffer solution is connected to the capillary through a flow channel and the switching valve. After switching the valve, the first passage is incorporated into the flow channel between the buffer solution and the capillary being filled. Then, the sample is electro-kinetically injected into the capillary. When conducting genetic polymorphism by electrophoresis, temperature control elements are provided to maintain the capillary at a predetermined temperature and a DNA sample device is provided to heat the sample to a temperature higher than a disassociation temperature thereof for directly injecting the heated sample into the capillary.
摘要翻译：通过毛细管电泳分析具有数千个碱基的核酸样品。电泳部分设置有填充有琼脂糖凝胶的第一毛细管和填充有聚丙烯酰胺凝胶的第二毛细管。柱内检测器与第二毛细管并入，用于光学检测。为了用凝胶填充毛细管，将溶液在高压下从第一流动通道通过切换阀进入连接到毛细管的第二流动通道。为了在毛细管中注入样品，将样品注射器连接到切换阀通道，并且缓冲溶液通过流动通道和切换阀连接到毛细管。在切换阀之后，第一通道被并入缓冲溶液和被填充的毛细管之间的流动通道中。然后，将样品电动注射到毛细管中。当通过电泳进行遗传多态性时，提供温度控制元件以将毛细管保持在预定温度，并且提供DNA样品装置以将样品加热到高于其解离温度的温度，以将加热的样品直接喷射到毛细管中。

5. 发明授权

US4604543A Multi-element ultrasonic transducer 失效
标题翻译：多元超声波换能器
公开(公告)号：US4604543A
公开(公告)日：1986-08-05
申请号：US676314
申请日：1984-11-29
申请人： Shinichiro Umemura , Hiroshi Takeuchi , Kageyoshi Katakura , Ryuichi Shinomura
发明人： Shinichiro Umemura , Hiroshi Takeuchi , Kageyoshi Katakura , Ryuichi Shinomura
IPC分类号： B06B1/06 , H01L41/08
CPC分类号： B06B1/0622
摘要： A multi-element ultrasonic transducer in which elements are arrayed and in which a plate-shaped piezoelectric material has its one face formed with a uniform electrode and its other face formed alternately with electrodes corresponding to the respective elements and electrodes for separating the elements. These electrodes for the element separation are connected the uniform electrode opposed thereto and is fed with a ground potential. On the other hand, the electrodes corresponding to the respective elements are fed individually with transmitting and receiving signals independently of the elements so that the electronic scanning or focusing operations can be achieved.
摘要翻译：一种多元件超声波换能器，其中排列有元件，其中板形压电材料的一面形成有均匀的电极，其另一面与电极对应地形成，电极对应于各元件和用于分离元件的电极。用于元件分离的这些电极与与其相对的均匀电极连接并且被馈送有接地电位。另一方面，对应于各个元件的电极单独地馈送发送和接收信号，独立于元件，使得可以实现电子扫描或聚焦操作。

6. 发明授权

US08460191B2 Ultrasonic medical diagnostic device for imaging changes with time 有权
标题翻译：超声波医疗诊断装置随时间变化
公开(公告)号：US08460191B2
公开(公告)日：2013-06-11
申请号：US11914962
申请日：2006-05-18
申请人： Hideki Yoshikawa , Takashi Azuma , Kenichi Kawabata , Kazuaki Sasaki , Shinichiro Umemura
发明人： Hideki Yoshikawa , Takashi Azuma , Kenichi Kawabata , Kazuaki Sasaki , Shinichiro Umemura
IPC分类号： A61B8/00
CPC分类号： A61B8/5207 , A61B5/11 , A61B8/08 , A61B8/461 , A61B8/463 , G06T5/50 , G06T7/223 , G06T2207/10132 , G06T2207/30101
摘要： An diagnostic imaging apparatus for imaging information changing with time and displaying it in real time, composed of an ultrasonic probe (2), having piezoelectric elements arranged in an array form that transmit ultrasonic waves to a target object (1) and acquires a reflection signal from the target object; a body movement measuring unit (12) that constitutes a two-dimensional ultrasonic image using the reflection signal acquired by the ultrasonic probe, sets, in the image plane, a plurality of measuring areas used for measuring the body movement of the target object, and measures the body movement and deformation amounts in the measuring areas; and an image accumulating (subtracting) unit for accumulating or subtracting images using body movement measured by the body movement measurement unit.
摘要翻译：一种诊断成像装置，用于对随时间变化的图像信息随时间变化并实时显示，该超声波探头由超声波探头（2）组成，该超声波探头具有排列成阵列形式的压电元件，以将超声波传送到目标物体（1）并获取反射信号从目标对象; 使用由超声波探头取得的反射信号构成二维超声波图像的身体运动测量单元（12）在图像平面中设置用于测量目标物体的身体运动的多个测量区域，以及测量测量区域的身体运动和变形量; 以及用于通过由身体运动测量单元测量的身体运动来累积或减去图像的图像累积（减去）单元。

7. 发明授权

US08388536B2 Ultrasonic imaging apparatus 有权
标题翻译：超声波成像装置
公开(公告)号：US08388536B2
公开(公告)日：2013-03-05
申请号：US12545975
申请日：2009-08-24
申请人： Takashi Azuma , Shinichiro Umemura
发明人： Takashi Azuma , Shinichiro Umemura
IPC分类号： A61B8/00
CPC分类号： G01S15/8954 , G01S7/52022 , G01S7/52046 , G01S15/104 , G01S15/8959 , G01S15/8961
摘要： In an ultrasonic contrast imaging method in which signals specific to a contrast agent are extracted to form an image, imaging is performed with the following three well-balanced properties: frame rate, spatial resolution, and contrast-agent selectivity. A first chirp signal whose frequency increases with time and a second chirp signal obtained by inverting the first chirp signal about the time axis are used, and they are individually transmitted and received. A decoder having decode filters each adapted for a coded sequence, which is obtained when the chirp signal is decomposed into a pulse signal and a coded sequence, is provided. The decode filters are adapted for echo signals received in response to two chirp signals, respectively, and outputs of the two decode filters are input to a subtractor, whereby the difference therebetween is determined. Thus, contrast-agent selectivity is balanced with spatial resolution.
摘要翻译：在提取特定于造影剂的信号以形成图像的超声波对比度成像方法中，使用以下三个良好平衡的特性进行成像：帧速率，空间分辨率和造影剂选择性。使用其频率随时间增加的第一啁啾信号和通过使关于时间轴的第一啁啾信号反相而获得的第二啁啾信号，并且它们被单独发送和接收。一种具有解码滤波器的解码器，每个解码滤波器适用于当线性调频信号被分解为脉冲信号和编码序列时获得的编码序列。解码滤波器适用于响应于两个啁啾信号而接收的回波信号，并且两个解码滤波器的输出被输入到减法器，从而确定它们之间的差异。因此，造影剂选择性与空间分辨率平衡。

8. 发明申请

US20120050721A1 Finger identification apparatus 有权
标题翻译：手指识别装置
公开(公告)号：US20120050721A1
公开(公告)日：2012-03-01
申请号：US13200857
申请日：2011-10-04
申请人： Akio Nagasaka , Takafumi Miyatake , Naoto Miura , Yoshiaki Amano , Yoshimi Kasai , Shinichiro Umemura , Miyuki Kono
发明人： Akio Nagasaka , Takafumi Miyatake , Naoto Miura , Yoshiaki Amano , Yoshimi Kasai , Shinichiro Umemura , Miyuki Kono
IPC分类号： G06K9/74
CPC分类号： G06K9/00067 , G06K9/00013 , G06K9/00362 , G06K9/00919 , G06K2009/00932
摘要： An identification apparatus keeps the conditions for imaging uniform among successive identifications, and requires a user to perform only a series of simple maneuvers. The apparatus comprises a guide member, a light source, and an imaging unit. The guide member includes a pattern or structure for a user to position his/her finger thereon or to approach his/her specific finger region thereto. A contact member is located in the guide member where a fingertip is positioned. An optical opening is formed at a position coincident with where a finger to be imaged should be placed. The light source radiates near-infrared light through the portion of the finger to be imaged. The imaging means acquires an image of the finger, and the apparatus compares the image to previously registered images. The apparatus may also include dual light sources power saving functionality, and means for limiting the interference of external light sources.
摘要翻译：识别装置在连续标识之间保持成像均匀的条件，并且要求用户仅执行一系列简单的操作。该装置包括导向件，光源和成像单元。引导构件包括用于使用者将他/她的手指放置在其上或者使其/特定手指区域接近的图案或结构。接触构件位于引导构件中，其中指尖被定位。在与要成像的手指放置的位置重合的位置处形成光学开口。光源通过要被成像的手指的部分辐射近红外光。成像装置获取手指的图像，并且该装置将图像与先前登记的图像进行比较。该装置还可以包括双光源节电功能，以及用于限制外部光源的干扰的装置。

9. 发明申请

US20100280376A1 ULTRASONIC IMAGING APPARATUS 有权
标题翻译：超声波成像设备
公开(公告)号：US20100280376A1
公开(公告)日：2010-11-04
申请号：US12810327
申请日：2008-08-28
申请人： Shinichiro Umemura , Takashi Azuma
发明人： Shinichiro Umemura , Takashi Azuma
IPC分类号： A61B8/14
CPC分类号： A61B8/481
摘要： An echo signal reflected from a microbubble contrast agent is discriminated from an echo signal generated upon reflection of a nonlinearly propagated transmission pulse from the body tissues without degradation of the axial resolution, by performing transmission/reception twice or less which would hardly decrease the imaging speed. By detecting a difference in phase of the second harmonic component based on the fundamental component included in the echo signal, an echo signal generated upon nonlinear reflection from a microbubble contrast agent is discriminated from an echo signal generated upon linear reflection of a nonlinearly propagated transmission pulse from the body tissues. The phase of the second harmonic component is detected through phase sensitive detection in which the square of the fundamental component is used as a reference wave. Concurrently, a pulse inversion method is used to extract the second harmonic component included in the original echo signal, whereby degradation of the axial resolution is prevented.
摘要翻译：从微泡造影剂反射的回波信号与通过非线性传播的来自身体组织的传播脉冲反射而产生的回波信号进行区分，而不会降低轴向分辨率，通过执行两次或更少的几乎不降低成像速度的发送/接收。通过基于包含在回波信号中的基波分量来检测二次谐波分量的相位差，从微泡造影剂的非线性反射产生的回波信号与在非线性传播的传输脉冲的线性反射时产生的回波信号从身体组织。通过使用基波分量的平方作为基准波的相位检测来检测二次谐波分量的相位。同时，使用脉冲反转方法来提取包括在原始回波信号中的二次谐波分量，由此防止轴向分辨率的劣化。

10. 发明授权

US07824336B2 Ultrasonic apparatus for diagnosis and therapy 有权
标题翻译：超声波诊断和治疗设备
公开(公告)号：US07824336B2
公开(公告)日：2010-11-02
申请号：US11336849
申请日：2006-01-23
申请人： Kenichi Kawabata , Nami Sugita , Shinichiro Umemura
发明人： Kenichi Kawabata , Nami Sugita , Shinichiro Umemura
IPC分类号： A61B8/00
CPC分类号： A61B8/08 , A61B8/481 , A61B2090/378 , A61N7/02
摘要： An ultrasonic apparatus for diagnosis and therapy is provided with plural ultrasound probes for generating ultrasound waves for phase shift, diagnosis, and therapy. A first control part causes phase shift in a nano droplet ultrasound contrast agent, while a second control part detects the phase shift of the nano droplet ultrasound contrast agent using ultrasound echo detected by an echo detection device. A difference calculation device calculates a difference of the detected phase shift over time, and a positioning device determines a target position where the difference is produced. A third control part is also provided for exposing a decided target area to the ultrasound waves for therapy.
摘要翻译：用于诊断和治疗的超声波装置设置有用于产生用于相移，诊断和治疗的超声波的多个超声波探头。第一控制部分引起纳米液滴超声造影剂中的相移，而第二控制部分使用由回波检测装置检测的超声回波来检测纳米液滴超声造影剂的相移。差分计算装置计算检测到的相移随时间的差异，并且定位装置确定产生差异的目标位置。还提供了第三控制部件，用于将决定的目标区域暴露于用于治疗的超声波。

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