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    • 2. 发明授权
    • Device, method, and system for separation and detection of biomolecules and cells
    • 用于分离和检测生物分子和细胞的装置,方法和系统
    • US08512559B2
    • 2013-08-20
    • US11281891
    • 2005-11-18
    • Shriram RamanathanChang-Min Park
    • Shriram RamanathanChang-Min Park
    • G01N33/553C02F1/48
    • G01N33/553B82Y15/00B82Y25/00B82Y30/00C02F2209/36G01N33/54326G01N33/5438G01N33/569
    • Embodiments of the invention relate to device, method, and system for separation and/or detection of biological cells and biomolecules using micro-channels, magnetic interactions, and magnetic tunnel junctions. The micro-channels can be integrated into a microfluidic device that may be part of an integrated circuit. Magnetic interactions used for the separation are created, in part, by magnetic stripes associated with the micro-channels. Detection of biological cells and biomolecules is effectuated by a magnetic tunnel junction sensor that comprises two ferromagnetic layers separated by a thin insulating layer. The magnetic tunnel junction sensor can be integrated into a silicon based device, such a microfluidic device, an integrated circuit, or a microarray to achieve rapid and specific separation and/or detection of biomolecules and cells.
    • 本发明的实施方案涉及使用微通道,磁相互作用和磁性隧道结分离和/或检测生物细胞和生物分子的装置,方法和系统。 微通道可以集成到可以是集成电路的一部分的微流体装置中。 用于分离的磁相互作用部分地由与微通道相关联的磁条产生。 生物细胞和生物分子的检测由磁隧道结传感器实现,磁传感器包括由薄绝缘层分隔的两个铁磁层。 磁性隧道结传感器可以集成到基于硅的装置,如微流体装置,集成电路或微阵列中,以实现生物分子和细胞的快速和特异性分离和/或检测。
    • 7. 发明申请
    • Nanoscale Oxide Coatings
    • 纳米氧化物涂料
    • US20100227083A1
    • 2010-09-09
    • US12519168
    • 2007-12-18
    • Shriram RamanathanChia-Lin Chang
    • Shriram RamanathanChia-Lin Chang
    • C23C8/10C23C14/08
    • C23C8/10B82Y30/00C23C14/5853C23C18/14
    • In various aspects, the present inventions provide methods for forming corrosion resistant oxide coatings on metals and/or improving the corrosion resistance of existing native oxide coatings. In various aspects, provided are methods for forming corrosion resistant oxide coatings on metals surfaces that are immersed in an aqueous solution. Various embodiments of various aspects of the present inventions can provide a scalable process for the formation of corrosion resistant coatings on metals in a manner that does not require high-vacuum technology, can be adapted to large structures, such as ships or aircraft, and in various aspects and embodiments can improve quality of existing oxide films on a metal or alloy surface.
    • 在各个方面,本发明提供了在金属上形成耐腐蚀氧化物涂层和/或提高现有氧化物涂层的耐腐蚀性的方法。 在各个方面,提供了在金属表面上形成浸渍在水溶液中的耐腐蚀氧化物涂层的方法。 本发明的各个方面的各种实施方案可以提供用于以不需要高真空技术的方式在金属上形成耐腐蚀涂层的可伸缩工艺,可适用于诸如船舶或航空器的大型结构,以及 各个方面和实施例可以提高金属或合金表面上现有氧化膜的质量。