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1. 发明授权

US09526457B2 Predictive intervertebral disc degeneration detection engine 有权
标题翻译：预测椎间盘变性检测引擎
公开(公告)号：US09526457B2
公开(公告)日：2016-12-27
申请号：US14591017
申请日：2015-01-07
申请人： Shuo Li , Sudhakar Tummala , Kengyeow Tay , Walter Romano , Derek Ho , Said Osman
发明人： Shuo Li , Sudhakar Tummala , Kengyeow Tay , Walter Romano , Derek Ho , Said Osman
IPC分类号： G06K9/00 , A61B5/00 , A61B6/03 , G06F19/00 , A61B5/055
CPC分类号： A61B5/7275 , A61B5/055 , A61B5/4514 , A61B5/4566 , A61B6/032 , A61B2576/02 , G06F19/00 , G06F19/321 , G16H40/63 , G16H50/20
摘要： Systems, methods and computer program products for facilitating the prognosis of degenerative disc disorder (DDD) are provided. In one aspect, intervertebral disc loss is predicted based on receiving image data comprising one or more images of the human spine; segmenting, using a processor, disc regions of said one or more images; generating, using the processor, individual biomarkers based on texture features of said segmented disc regions; generating, using the processor, a predicting intervertebral disc loss based in part on the prognostic marker generated from the individual biomarkers.
摘要翻译：提供了用于促进退行性椎间盘疾病（DDD）预后的系统，方法和计算机程序产品。在一个方面，基于接收包括人脊柱的一个或多个图像的图像数据来预测椎间盘丢失; 使用处理器分割所述一个或多个图像的光盘区域; 基于所述分段的盘区域的纹理特征生成使用所述处理器的各个生物标志物; 使用处理器产生部分地基于从各个生物标志物产生的预后标记物的预测性椎间盘丢失。

2. 发明授权

US08478012B2 Methods, apparatus and articles of manufacture to process cardiac images to detect heart motion abnormalities 有权
标题翻译：用于处理心脏图像以检测心脏运动异常的方法，装置和制品
公开(公告)号：US08478012B2
公开(公告)日：2013-07-02
申请号：US12633519
申请日：2009-12-08
申请人： Kumaradevan Punithakumar , Shuo Li , Ismail Ben Ayed , Ian Ross , Ali Islam , Richard Rankin
发明人： Kumaradevan Punithakumar , Shuo Li , Ismail Ben Ayed , Ian Ross , Ali Islam , Richard Rankin
IPC分类号： G06K9/36
CPC分类号： G06T7/0012 , G06K9/6207 , G06K9/6215 , G06K2209/05 , G06T7/0016 , G06T7/277 , G06T2207/10081 , G06T2207/10088 , G06T2207/30048
摘要： Example methods, apparatus and articles of manufacture to process cardiac images to detect heart motion abnormalities are disclosed. A disclosed example method includes adapting a state of a state-space model based on a plurality of cardiac images to characterize motion of a heart, computing an information-theoretic metric from the state of the state-space model, and comparing the information-theoretic metric to a threshold to determine whether the motion of the heart is abnormal.
摘要翻译：公开了用于处理心脏图像以检测心脏运动异常的示例性方法，装置和制品。公开的示例性方法包括基于多个心脏图像来适应状态空间模型的状态以表征心脏的运动，从状态 - 空间模型的状态计算信息理论度量，以及将信息理论度量到阈值，以确定心脏的运动是否异常。

3. 发明申请

US20120157626A1 Hybrid Superparamagnetic Iron Oxide Nanoparticles And Polyethylenimine As A Magnetoplex For Gene Transfection 有权
标题翻译：混合超顺磁性氧化铁纳米颗粒和聚乙烯亚胺作为基因转染的磁复合体
公开(公告)号：US20120157626A1
公开(公告)日：2012-06-21
申请号：US13074491
申请日：2011-03-29
申请人： Li-Fang Wang , Shuo-Li Sun , Yu-Lun Lo
发明人： Li-Fang Wang , Shuo-Li Sun , Yu-Lun Lo
IPC分类号： C08G63/91 , B82Y30/00
CPC分类号： A61K48/0025 , A61K48/0033 , A61K48/0041 , B82Y5/00 , B82Y30/00 , C08K9/04 , C08K9/08 , C08K2201/005 , C08K2201/01 , C08K2201/013 , C12N15/85
摘要： Disclosed are the nanoparticle and the method for the same, and the preparing method includes steps of mixing polyethylenimine (PEI) with the poly(acrylic acid)-bound iron oxide (PAAIO) to form a PEI-PAAIO polyelectrolyte complex (PEC) and mixing the PEI-PAAIO PEC with genetic material such as plasmid DNA to form the PEI-PAAIO/pDNA magnetic nanoparticle. The PEI-PAAIO/pDNA magnetoplex is highly water dispersible and suitable for long term storage, shows superparamagnetism, low cytotoxicity, high stability and nice transfection efficiency, and thus the PEI-PAAIO PEC can replace PEI as a non-viral gene vector.
摘要翻译：公开了纳米颗粒及其制备方法，其制备方法包括将聚乙烯亚胺（PEI）与聚（丙烯酸）键合的氧化铁（PAAIO）混合以形成PEI-PAAIO聚电解质络合物（PEC）和混合 PEI-PAAIO PEC与遗传物质如质粒DNA形成PEI-PAAIO / pDNA磁性纳米颗粒。 PEI-PAAIO / pDNA磁复合物具有高水分散性，适合长期保存，显示出超顺磁性，低细胞毒性，高稳定性和良好的转染效率，因此PEI-PAAIO PEC可代替PEI作为非病毒基因载体。

4. 发明申请

US20120106823A1 Systems and Methods for Computer Aided Analysis of Images 有权
标题翻译：图像计算机辅助分析系统与方法
公开(公告)号：US20120106823A1
公开(公告)日：2012-05-03
申请号：US13348379
申请日：2012-01-11
申请人： Prakash Mahesh , Shuo Li , Dave Roeder , Ian Ross
发明人： Prakash Mahesh , Shuo Li , Dave Roeder , Ian Ross
IPC分类号： G06K9/34
CPC分类号： G06K9/3233 , G06K2209/051 , G06T7/11 , G06T7/162 , G06T7/215 , G06T2207/10072 , G06T2207/30048
摘要： Certain embodiments of the present technology provide systems, methods and computer instructions for computer aided analysis of images. In certain embodiments, for example, such a method includes: isolating a motion area in an image; segmenting the image; utilizing a support vector machine to identify a region of interest in the image; utilizing a graph-cut algorithm to refine the region of interest; and verifying the region of interest. In certain embodiments, for example, such a method further includes: aligning a set of images and/or outputting a set of aligned images sequentially. In certain embodiments, the systems, methods and computer instructions disclosed herein can be used to aid analysis of cardiac images, for example. In certain embodiments, the systems, methods and computer instructions disclosed herein can be used to aid analysis of four dimensional images, for example.
摘要翻译：本技术的某些实施例提供了用于计算机辅助分析图像的系统，方法和计算机指令。在某些实施例中，例如，这种方法包括：隔离图像中的运动区域; 分割图像; 利用支持向量机来识别图像中的感兴趣区域; 利用图形剪切算法来细化感兴趣的区域; 并验证感兴趣的区域。在某些实施例中，例如，这种方法还包括：对齐一组图像和/或顺序地输出一组对准的图像。在某些实施例中，本文公开的系统，方法和计算机指令可用于帮助例如心脏图像的分析。在某些实施例中，本文公开的系统，方法和计算机指令可用于辅助例如四维图像的分析。

5. 发明申请

US20060020953A1 External optical disk drive assembly 有权
标题翻译：外部光盘驱动器总成
公开(公告)号：US20060020953A1
公开(公告)日：2006-01-26
申请号：US11008322
申请日：2004-12-10
申请人： Chien Huang , Yu-Shuo Li
发明人： Chien Huang , Yu-Shuo Li
IPC分类号： G11B33/02
CPC分类号： G11B33/121 , G11B33/122
摘要： The present invention discloses an external optical disk drive assembly, which comprises a slim internal optical disk drive including a first transmission port; and an external module being disposed outside the slim internal optical disk drive and electrically coupled to the first transmission port, so that the slim internal optical disk drive is converted into the external optical disk drive, characterized in that the external module is disposed within the area covered by the slim internal optical disk drive.
摘要翻译：本发明公开了一种外部光盘驱动器组件，其包括具有第一传输端口的细长内部光盘驱动器; 外部模块设置在薄型内部光盘驱动器的外部并电耦合到第一传输端口，使得细长的内部光盘驱动器被转换为外部光盘驱动器，其特征在于，外部模块设置在该区域内被细长的内部光盘驱动器覆盖。

6. 发明授权

US08639060B2 System and method for image based multiple-modality cardiac image alignment 有权
标题翻译：用于基于图像的多模态心脏图像对准的系统和方法
公开(公告)号：US08639060B2
公开(公告)日：2014-01-28
申请号：US13421629
申请日：2012-03-15
申请人： Shuo Li , Prakash Mahesh , Dave Roeder , Richard Rankin
发明人： Shuo Li , Prakash Mahesh , Dave Roeder , Richard Rankin
IPC分类号： G06T7/00 , G06F3/04845
CPC分类号： G06T7/20 , G06K9/32 , G06T7/33 , G06T7/38 , G06T2207/10076 , G06T2207/10081 , G06T2207/10088 , G06T2207/30048
摘要： Certain embodiments of the present invention provide a system and method for temporally aligning a plurality of cardiac image sequences. The method includes performing a locally linear embedding algorithm on a first set of cardiac image sequences and on a second set of cardiac image sequences. A graphical representation is created for the first set of cardiac image sequences and the second set of cardiac image sequences. A determination is made whether the first set of cardiac image sequences and the second set of cardiac image sequences were generated from a similar point of view. If a similar point of view is found, the first graphical representation and the second graphical representation are aligned using a minimization function. If a similar point of view is not found, the graphs are aligned with a template and then aligned with each other using the minimization function.
摘要翻译：本发明的某些实施例提供了一种用于在时间上对准多个心脏图像序列的系统和方法。该方法包括对第一组心脏图像序列和第二组心脏图像序列执行局部线性嵌入算法。为第一组心脏图像序列和第二组心脏图像序列创建图形表示。确定第一组心脏图像序列和第二组心脏图像序列是否从类似的观点生成。如果找到类似的观点，则使用最小化函数来对齐第一图形表示和第二图形表示。如果没有找到类似的观点，图形将与模板对齐，然后使用最小化函数对齐。

7. 发明授权

US08144930B2 Systems and methods for tracking images 有权
标题翻译：用于跟踪图像的系统和方法
公开(公告)号：US08144930B2
公开(公告)日：2012-03-27
申请号：US12325226
申请日：2008-11-30
申请人： Shuo Li , Ismail Ben Ayed , Ian Ross , Richard Rankin
发明人： Shuo Li , Ismail Ben Ayed , Ian Ross , Richard Rankin
IPC分类号： G06K9/00
CPC分类号： G06K9/4642 , G06T7/11 , G06T2207/20104 , G06T2207/30048
摘要： Image tracking as described herein can include: segmenting a first image into regions; determining an overlap of intensity distributions in the regions of the first image; and segmenting a second image into regions such that an overlap of intensity distributions in the regions of the second image is substantially similar to the overlap of intensity distributions in the regions of the first image. In certain embodiments, images can depict a heart at different points in time and the tracked regions can be the left ventricle cavity and the myocardium. In such embodiments, segmenting the second image can include generating first and second curves that track the endocardium and epicardium boundaries, and the curves can be generated by minimizing functions containing a coefficient based on the determined overlap of intensity distributions in the regions of the first image.
摘要翻译：如本文所述的图像跟踪可以包括：将第一图像分割成区域; 确定所述第一图像的区域中的强度分布的重叠; 以及将第二图像分割成区域，使得所述第二图像的区域中的强度分布的重叠基本上类似于所述第一图像的区域中的强度分布的重叠。在某些实施例中，图像可以在不同的时间点描绘心脏，并且所跟踪的区域可以是左心室和心肌。在这样的实施例中，分割第二图像可以包括产生跟踪心内膜和心外膜边界的第一曲线和第二曲线，并且可以通过基于所确定的第一图像的区域中的强度分布的重叠来最小化包含系数的函数来生成曲线。

8. 发明申请

US20110064290A1 METHODS, APPARATUS AND ARTICLES OF MANUFACTURE TO TRACK ENDOCARDIAL MOTION 有权
标题翻译：方法，装置和制造物品跟踪内部运动
公开(公告)号：US20110064290A1
公开(公告)日：2011-03-17
申请号：US12636470
申请日：2009-12-11
申请人： Kumaradevan Punithakumar , Shuo Li , Ismail Ben Ayed , Ian Ross , Ali Islam , Richard Rankin
发明人： Kumaradevan Punithakumar , Shuo Li , Ismail Ben Ayed , Ian Ross , Ali Islam , Richard Rankin
IPC分类号： G06K9/62
CPC分类号： G06T7/0012 , G06K9/6207 , G06K9/6215 , G06K2209/05 , G06T7/0016 , G06T7/277 , G06T2207/10081 , G06T2207/10088 , G06T2207/30048
摘要： Example methods, apparatus and articles of manufacture to track endocardial motion are disclosed. A disclosed example method includes segmenting a plurality of cardiac images of a left ventricle to form respective ones of a plurality of segmented images, updating a plurality of models based on the plurality of segmented images to form respective ones of a plurality of motion estimates for the left ventricle, computing a plurality of probabilities for respective ones of the plurality of models, and computing a weighted sum of the plurality of motion estimates based on the plurality of probabilities, the weighted sum representing a predicted motion of the left ventricle.
摘要翻译：公开了用于跟踪心内膜运动的示例性方法，装置和制品。所公开的示例性方法包括分割左心室的多个心脏图像以形成多个分割图像中的相应图像，基于多个分割图像来更新多个模型，以形成多个分割图像的多个运动估计计算多个模型中的各个模型的多个概率，以及基于所述多个概率来计算所述多个运动估计的加权和，所述加权和代表所述左心室的预测运动。

9. 发明申请

US20110052175A1 METHOD AND DEVICE FOR ADJUSTING WEIGHTING VALUES IN LIGHT METERING 有权
标题翻译：用于调整光度计中的称重值的方法和装置
公开(公告)号：US20110052175A1
公开(公告)日：2011-03-03
申请号：US12814475
申请日：2010-06-13
申请人： Shuo-Li Shih , Hsin-Yu Chen
发明人： Shuo-Li Shih , Hsin-Yu Chen
IPC分类号： G03B7/08
CPC分类号： G03B7/09979 , G03B7/08
摘要： A method for adjusting weighting values in light metering is provided. An input image is divided into multiple metering zones. The input image includes a number of pixel data, and the metering zones correspond to a number of exposure weighting values. It is determined whether the color of each pixel datum of the input image is skin color. For each metering zone, an amount of the pixel data determined as the skin color is calculated. The corresponding exposure weighting values of the metering zones are adjusted according to the calculated results.
摘要翻译：提供了一种用于调节光计量中的加权值的方法。输入图像被分成多个测光区域。输入图像包括多个像素数据，并且计量区域对应于多个曝光加权值。确定输入图像的每个像素基准的颜色是皮肤颜色。对于每个测光区域，计算确定为肤色的像素数据量。计量区域的相应曝光加权值根据计算结果进行调整。

10. 发明申请

US20090180675A1 SYSTEM AND METHOD FOR IMAGE BASED MULTIPLE-MODALITY CARDIAC IMAGE ALIGNMENT 有权
标题翻译：基于图像的多模态心脏图像对齐的系统与方法
公开(公告)号：US20090180675A1
公开(公告)日：2009-07-16
申请号：US12013939
申请日：2008-01-14
申请人： Shuo Li , Prakash Mahesh , Dave Roeder , Richard Rankin
发明人： Shuo Li , Prakash Mahesh , Dave Roeder , Richard Rankin
IPC分类号： A61B5/02
CPC分类号： G06T7/20 , G06K9/32 , G06T7/33 , G06T7/38 , G06T2207/10076 , G06T2207/10081 , G06T2207/10088 , G06T2207/30048
摘要： Certain embodiments of the present invention provide a system and method for temporally aligning a plurality of cardiac image sequences. The method includes performing a locally linear embedding algorithm on a first set of cardiac image sequences and on a second set of cardiac image sequences. A graphical representation is created for the first set of cardiac image sequences and the second set of cardiac image sequences. A determination is made whether the first set of cardiac image sequences and the second set of cardiac image sequences were generated from a similar point of view. If a similar point of view is found, the first graphical representation and the second graphical representation are aligned using a minimization function. If a similar point of view is not found, the graphs are aligned with a template and then aligned with each other using the minimization function.
摘要翻译：本发明的某些实施例提供了一种用于在时间上对准多个心脏图像序列的系统和方法。该方法包括对第一组心脏图像序列和第二组心脏图像序列执行局部线性嵌入算法。为第一组心脏图像序列和第二组心脏图像序列创建图形表示。确定第一组心脏图像序列和第二组心脏图像序列是否从类似的观点生成。如果找到类似的观点，则使用最小化函数来对齐第一图形表示和第二图形表示。如果没有找到类似的观点，图形将与模板对齐，然后使用最小化函数对齐。

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