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1. 发明授权

US08417343B2 Obstructive sleep apnea treatment devices, systems and methods 有权
标题翻译：阻塞性睡眠呼吸暂停治疗装置，系统和方法
公开(公告)号：US08417343B2
公开(公告)日：2013-04-09
申请号：US11907533
申请日：2007-10-12
申请人： Stephen L. Bolea , Thomas B. Hoegh , Bruce J. Persson , Robert E. Atkinson , Sidney F. Hauschild , Paula M. Kaplan , Brian D. Kuhnley , Keith E. Jasperson , Wondimeneh Tesfayesus , Christopher K. Thorp
发明人： Stephen L. Bolea , Thomas B. Hoegh , Bruce J. Persson , Robert E. Atkinson , Sidney F. Hauschild , Paula M. Kaplan , Brian D. Kuhnley , Keith E. Jasperson , Wondimeneh Tesfayesus , Christopher K. Thorp
IPC分类号： A61N1/36
CPC分类号： A61N1/3606 , A61B5/0809 , A61B5/4818 , A61B5/7239 , A61N1/0556 , A61N1/0558 , A61N1/3601 , A61N1/37229
摘要： Devices, systems and methods for nerve stimulation for OSA therapy.
摘要翻译：用于OSA治疗的神经刺激的装置，系统和方法。

2. 发明授权

US08326434B2 Medical electrode mounting 有权
标题翻译：医用电极安装
公开(公告)号：US08326434B2
公开(公告)日：2012-12-04
申请号：US12783107
申请日：2010-05-19
申请人： Sean Patrick Skubitz , Mary Boatwright , Stephen L. Bolea , Jessica L. Tower , Michael E. Metzler
发明人： Sean Patrick Skubitz , Mary Boatwright , Stephen L. Bolea , Jessica L. Tower , Michael E. Metzler
IPC分类号： A61N1/365
CPC分类号： A61N1/0553
摘要： A medical electrical lead electrode assembly includes an insulative carrier and at least one conductive component. The at least one conductive component includes an electrode portion disposed on a first side of the carrier and at least one tab extending away from the electrode portion, through the carrier to a second side of the carrier. The electrode portion of the at least one component includes an outward facing contact surface and an inward facing surface, the inward facing surface being disposed opposite the contact surface and against a surface of the first side of the carrier. The electrode assembly further includes a joint coupling a flexible elongate conductor to the tab of the at least one component on the second side of the carrier, and an insulative layer extending over the joint and the tab and the conductor, the insulative layer being bonded to the second side of the carrier.
摘要翻译：医疗电引线电极组件包括绝缘载体和至少一个导电组件。所述至少一个导电部件包括设置在所述载体的第一侧上的电极部分和至少一个突出部，所述突出部从所述电极部分延伸穿过所述载体延伸到所述载体的第二侧。所述至少一个部件的电极部分包括面向外的接触表面和面向内的表面，所述向内的表面设置成与所述接触表面相对并且抵靠所述载体的第一面的表面。电极组件还包括将柔性细长导体连接到载体第二侧上的至少一个部件的突出部的接头，以及在接头和突片和导体上延伸的绝缘层，绝缘层与承运人的第二面。

3. 发明授权

US08014874B2 Connection structures for extra-vascular electrode lead body 有权
标题翻译：超血管电极引线体的连接结构
公开(公告)号：US08014874B2
公开(公告)日：2011-09-06
申请号：US11836047
申请日：2007-08-08
申请人： Martin A. Rossing , Stephen L. Bolea , David W. Mayer , Aaron Hjelle , Thomas P. Crowley , Eric D. Irwin
发明人： Martin A. Rossing , Stephen L. Bolea , David W. Mayer , Aaron Hjelle , Thomas P. Crowley , Eric D. Irwin
IPC分类号： A61N1/05
CPC分类号： A61N1/3752 , A61N1/05 , A61N1/0551 , A61N1/0558 , H01R4/14 , H01R4/4863 , H01R13/5224 , H01R13/5804 , H01R2201/12
摘要： Connection structures on an extra-vascular electrode lead body improve strain relief and strengthen the transition region where electrical conductors carried by the lead body are joined to individual electrodes at the distal end of the lead. The electrodes include structure or mechanisms for externally securing the electrode assembly to a body part. A first connection structure is located on the lead body proximal the electrodes to anchor the lead body to a first anchor location in the body that generally moves in concert with the body part. A second connection structure is located on the lead body proximal to the first connection structure to anchor the lead body to a second anchor location that is at least partially independent of movement of the body part. The first and second anchor location are offset by a distance that is less than a distance between the first and second connection structures to provide strain relief for the electrodes.
摘要翻译：超血管电极引线体上的连接结构改善了应变消除，并且加强了由引线体承载的电导体连接到引线远端处的各个电极的过渡区域。电极包括用于将电极组件外部固定到主体部分的结构或机构。第一连接结构位于靠近电极的引线体上，以将引线主体锚固到主体中与身体部分一致移动的第一锚定位置。第二连接结构位于靠近第一连接结构的引线体上，以将引线主体锚固到至少部分地与主体部分的运动无关的第二锚定位置。第一和第二锚定位置偏移小于第一和第二连接结构之间的距离的距离，以为电极提供应变消除。

4. 发明申请

US20110196445A1 OBSTRUCTIVE SLEEP APNEA TREATMENT DEVICES, SYSTEMS AND METHODS 有权
公开(公告)号：US20110196445A1
公开(公告)日：2011-08-11
申请号：US13094371
申请日：2011-04-26
申请人： Stephen L Bolea , Thomas B. Hoegh , Bruce J. Persson , Robert E. Atkinson , Scott T. Mazar
发明人： Stephen L Bolea , Thomas B. Hoegh , Bruce J. Persson , Robert E. Atkinson , Scott T. Mazar
IPC分类号： A61N1/05 , A61N1/36 , A61F5/56
CPC分类号： A61N1/3606 , A61B5/0809 , A61B5/4818 , A61B5/7239 , A61N1/0556 , A61N1/0558 , A61N1/3601 , A61N1/37229
摘要： Devices, systems and methods for nerve stimulation for OSA therapy.

5. 发明申请

US20110160794A1 Obstructive Sleep Apnea Treatment Devices, Systems and Methods 审中-公开
标题翻译：阻塞性睡眠呼吸暂停治疗装置，系统和方法
公开(公告)号：US20110160794A1
公开(公告)日：2011-06-30
申请号：US12980840
申请日：2010-12-29
申请人： Stephen L. Bolea , Thomas B. Hoegh , Brian D. Kuhnley , Dale G. Suilmann , Bruce J. Persson , John P. Beck , Sidney F. Hauschild , Paula M. Kaplan , Adam K. Hoyhtya , Wondimeneh Tesfayesus , Robert E. Atkinson
发明人： Stephen L. Bolea , Thomas B. Hoegh , Brian D. Kuhnley , Dale G. Suilmann , Bruce J. Persson , John P. Beck , Sidney F. Hauschild , Paula M. Kaplan , Adam K. Hoyhtya , Wondimeneh Tesfayesus , Robert E. Atkinson
IPC分类号： A61N1/36
CPC分类号： A61N1/3601 , A61B5/0538 , A61B5/4818 , A61N1/0556 , A61N1/3611 , A61N1/36139
摘要： Devices, systems and methods of neurostimulation for treating obstructive sleep apnea.
摘要翻译：用于治疗阻塞性睡眠呼吸暂停的神经刺激的装置，系统和方法。

6. 发明申请

US20110029056A1 EXPANDABLE SYSTEMS FOR MEDICAL ELECTRICAL STIMULATION 有权
标题翻译：用于医疗电刺激的可扩展系统
公开(公告)号：US20110029056A1
公开(公告)日：2011-02-03
申请号：US12846547
申请日：2010-07-29
申请人： Sean P. Skubitz , Stephen L. Bolea , Paula M. Kaplan , Mary M. Morris
发明人： Sean P. Skubitz , Stephen L. Bolea , Paula M. Kaplan , Mary M. Morris
IPC分类号： A61N1/05
CPC分类号： A61N1/0553 , A61N1/0558
摘要： A medical system for electrical stimulation includes a first column of electrodes, a second column of electrodes, an expandable member disposed between first and second columns, and an expansion mechanism adapted to transmit an externally applied pressure to the expandable member. The pressure expands the expandable member in order to force the first column of electrodes apart from the second column of electrodes. The first and second columns, disposed side-by-side, may be inserted through a percutaneous needle and into a epidural space, alongside a spinal cord; after insertion, the first column may be forced apart from the second column by applying the pressure to the expandable member.
摘要翻译：用于电刺激的医疗系统包括第一列电极，第二电极列，设置在第一和第二列之间的可扩张构件以及适于将外部施加的压力传递到可扩张构件的膨胀机构。压力使可膨胀构件膨胀，以迫使第一列电极与第二列电极分开。并排设置的第一和第二列可以穿过经皮针插入到与脊髓一起的硬膜外腔中; 在插入之后，通过向可膨胀构件施加压力，第一柱可以被迫离开第二柱。

7. 发明授权

US07831311B2 Reduced axial stiffness implantable medical lead 有权
标题翻译：降低轴向刚度可植入医用铅
公开(公告)号：US07831311B2
公开(公告)日：2010-11-09
申请号：US11119416
申请日：2005-04-29
申请人： Thomas E. Cross, Jr. , James M. Olsen , Stephen L. Bolea
发明人： Thomas E. Cross, Jr. , James M. Olsen , Stephen L. Bolea
IPC分类号： A61N1/05
CPC分类号： A61N1/056
摘要： An implantable lead has a lead body construction designed to accommodate loading forces exerted on the lead body during patient movement. The lead body is sufficiently stretchable to resist forces that could otherwise cause lead failure, axial migration of the electrodes, anchor damage, or tissue damage. The lead body may include a variety of features that reduce the axial stiffness of the lead without significantly impacting the operation and structural integrity of lead components, such as electrodes, conductors and insulators.
摘要翻译：可植入引线具有引线本体结构，其设计用于在患者移动期间适应施加在引线本体上的负载力。引线体具有足够的拉伸能力以抵抗否则会导致引线故障，电极的轴向迁移，锚固损坏或组织损伤的力。引线体可以包括减少引线的轴向刚度的各种特征，而不会显着地影响诸如电极，导体和绝缘体的引线部件的操作和结构完整性。

8. 发明授权

US07519432B2 Implantable medical lead with helical reinforcement 有权
标题翻译：可植入医用铅带螺旋加固
公开(公告)号：US07519432B2
公开(公告)日：2009-04-14
申请号：US11119389
申请日：2005-04-29
申请人： Stephen L. Bolea , Thomas C. Bischoff , Thomas E. Cross, Jr. , James M. Olsen
发明人： Stephen L. Bolea , Thomas C. Bischoff , Thomas E. Cross, Jr. , James M. Olsen
IPC分类号： A61N1/05
CPC分类号： A61N1/056
摘要： An implantable lead has a lead body construction designed to accommodate loading forces exerted on the lead body during patient movement. The lead body may be sufficiently stretchable to resist forces that could otherwise cause lead failure, axial migration of the electrodes, anchor damage, or tissue damage. Increasing stretchability of a lead body can also increase the vulnerability of the lead body to flex fatigue, buckling fatigue, kinking, and crush. Therefore, the lead described herein includes a reinforcement to create a lead body that is resistant to flex fatigue, buckling fatigue, kinking and crush.
摘要翻译：可植入引线具有引线本体结构，其设计用于在患者移动期间适应施加在引线本体上的负载力。引线体可以是足够的可拉伸的以抵抗否则会导致引线故障，电极的轴向迁移，锚固损伤或组织损伤的力。引线体的增加拉伸性也可以增加引线体疲劳疲劳，弯曲疲劳，扭结和挤压的脆弱性。因此，本文所述的导线包括增强以产生耐挠曲疲劳，弯曲疲劳，扭结和挤压的引线体。

9. 发明申请

US20080177348A1 ELECTRODE CONTACT CONFIGURATIONS FOR AN IMPLANTABLE STIMULATOR 审中-公开
标题翻译：电极接触配置用于可植入刺激物
公开(公告)号：US20080177348A1
公开(公告)日：2008-07-24
申请号：US11933221
申请日：2007-10-31
申请人： Stephen L. Bolea , Robert S. Kieval , Bruce J. Persson , David J. Serdar , Peter T. Keith , Eric D. Irwin , Martin A. Rossing
发明人： Stephen L. Bolea , Robert S. Kieval , Bruce J. Persson , David J. Serdar , Peter T. Keith , Eric D. Irwin , Martin A. Rossing
IPC分类号： A61N1/05
CPC分类号： A61N1/05 , A61N1/08 , A61N1/36117 , A61N1/36185
摘要： An implantable stimulator, having at least one electrode contact array comprising multiple electrode contacts disposed on an external surface of said stimulator. The electrode contacts are configured to have a first polarity. At least one additional electrode contact is disposed on the external surface, the at least one additional electrode contact is configured to have a second polarity. One or more of the electrode contacts disposed on the stimulator are configured to deliver at least one or more of a monopolar stimulation and a multipolar stimulation.
摘要翻译：一种可植入刺激器，具有至少一个电极接触阵列，其包括设置在所述刺激器的外表面上的多个电极触点。电极触点被配置为具有第一极性。至少一个附加电极接触件设置在外表面上，所述至少一个附加电极接触件构造成具有第二极性。设置在刺激器上的一个或多个电极接触件被配置成输送单极刺激和多极刺激中的至少一个或多个。

10. 发明申请

US20080046049A1 NOVEL ASSEMBLY METHODS FOR MEDICAL ELECTRICAL LEADS 有权
标题翻译：医疗电气领域的新型组装方法
公开(公告)号：US20080046049A1
公开(公告)日：2008-02-21
申请号：US11465879
申请日：2006-08-21
申请人： Sean P. Skubitz , Mary L. Boatwright , Stephen L. Bolea , Jessica L. Tower , Michael E. Metzler
发明人： Sean P. Skubitz , Mary L. Boatwright , Stephen L. Bolea , Jessica L. Tower , Michael E. Metzler
IPC分类号： A61N1/04
CPC分类号： A61N1/05 , A61N1/0553 , Y10T29/49002 , Y10T29/4913
摘要： A method for making a medical electrical lead electrode assembly includes the steps of: forming an insulative carrier from an insulative material; coupling at least one conductive component to the carrier by inserting at least one tab of the at least one conductive component through the carrier, the tab extending away from an electrode portion of the component such that, after the tab is inserted, the electrode portion is disposed on a first side of the carrier and the tab is disposed on a second side of the carrier; coupling an elongate flexible conductor to the tab of the at least one component; and forming an insulative layer over the tab and the conductor on the second side of the carrier.
摘要翻译：制造医用电极电极组件的方法包括以下步骤：从绝缘材料形成绝缘载体; 通过将所述至少一个导电部件的至少一个突片插入所述载体，将所述至少一个导电部件耦合到所述载体，所述突片远离所述部件的电极部分延伸，使得在所述突片被插入之后，所述电极部分设置在所述载体的第一侧上，并且所述突片设置在所述载体的第二侧上; 将细长的柔性导体耦合到所述至少一个部件的突出部; 以及在所述突片和所述载体的第二侧上的导体上形成绝缘层。

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