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1. 发明申请

US20170166621A1 DUAL FUNCTION PROTEINS FOR TREATING METABOLIC DISORDERS 审中-公开
公开(公告)号：US20170166621A1
公开(公告)日：2017-06-15
申请号：US15248712
申请日：2016-08-26
申请人： Brian R. BOETTCHER , Shari Lynn CAPLAN , Susan E. CELLITTI , Douglas S. DANIELS , Norio HAMAMATSU , Bernhard Hubert GEIERSTANGER , Stuart LICHT , Andreas LOEW , Stephen Craig WELDON
发明人： Brian R. BOETTCHER , Shari Lynn CAPLAN , Susan E. CELLITTI , Douglas S. DANIELS , Norio HAMAMATSU , Bernhard Hubert GEIERSTANGER , Stuart LICHT , Andreas LOEW , Stephen Craig WELDON
IPC分类号： C07K14/605 , C07K14/50
摘要： The present invention relates to the identification of new proteins comprising fibroblast growth factor 21 (FGF21) and other metabolic regulators, including variants thereof, known to improve metabolic profiles in subjects to whom they are administered. Also disclosed are methods for treating FGF21-associated disorders, GLP-1-associated disorders, and Exendin-4-associated disorders, including metabolic conditions.

2. 发明申请

US20130079500A1 FUSION PROTEINS FOR TREATING METABOLIC DISORDERS 有权
公开(公告)号：US20130079500A1
公开(公告)日：2013-03-28
申请号：US13626194
申请日：2012-09-25
申请人： Brian R. Boettcher , Shari L. Caplan , Douglas S. Daniels , Norio Hamamatsu , Stuart Licht , Stephen Craig Weldon
发明人： Brian R. Boettcher , Shari L. Caplan , Douglas S. Daniels , Norio Hamamatsu , Stuart Licht , Stephen Craig Weldon
IPC分类号： C07K19/00
CPC分类号： A61K38/1825 , A61K38/00 , A61K45/06 , C07K14/50 , C07K2319/30
摘要： The invention relates to the identification of fusion proteins comprising polypeptide and protein variants of fibroblast growth factor 21 (FGF21) with improved pharmaceutical properties. Also disclosed are methods for treating FGF21-associated disorders, including metabolic conditions.

3. 发明申请

US20100200418A1 PROCESS FOR ELECTROSYNTHESIS OF ENERGETIC MOLECULES 有权
标题翻译：电化学分子的电化学方法
公开(公告)号：US20100200418A1
公开(公告)日：2010-08-12
申请号：US12704748
申请日：2010-02-12
申请人： Stuart Licht
发明人： Stuart Licht
IPC分类号： C25B1/00 , C25B9/00
CPC分类号： C25B1/00 , B01J19/128 , C25B9/00 , Y02P20/134
摘要： A process for the production of energetically rich compounds comprising: using externally supplied thermal energy to heat an electrolyzable compound to a temperature greater than the ambient temperature; generating electricity from a solar electrical photovoltaic component; subjecting the heated electrolyzable compound to electrolysis with the solar generated electricity to generate an energetically rich electrolytic product.
摘要翻译：一种用于生产富能化合物的方法，包括：使用外部供应的热能将可电解化合物加热到大于环境温度的温度; 从太阳能光伏组件发电; 使加热的可电解化合物用太阳能发电电解，产生富含能量的电解产物。

4. 发明授权

US06387569B1 Conductive iron-based storage battery 失效
标题翻译：导电铁基蓄电池
公开(公告)号：US06387569B1
公开(公告)日：2002-05-14
申请号：US09519996
申请日：2000-03-06
申请人： Stuart Licht
发明人： Stuart Licht
IPC分类号： H01M402
CPC分类号： H01M4/364 , H01M4/5825 , H01M4/625 , H01M6/04 , H01M10/24 , H01M2004/028 , Y02E60/124
摘要： An electric storage battery having a solid phase Fe(VI) salt cathode. The anode may be any of a large variety of conventional anode materials capable of being oxidized. The cathode and anode are located in separate half-cells which are in electrochemical contact through an electrically neutral ionic conductor. Small material additions to the Fe(VI) salt containing half cell can be used to control the conductance and electrochemical characteristics of the battery.
摘要翻译：一种具有固相Fe（VI）盐阴极的蓄电池。阳极可以是能够被氧化的各种常规阳极材料中的任何一种。阴极和阳极位于通过电中性离子导体进行电化学接触的分开的半电池中。可以使用含Fe（VI）盐的半电池的小材料添加物来控制电池的电导率和电化学特性。

5. 发明授权

US09368846B2 Vanadium boride air multiple electron high capacity battery 有权
标题翻译：钒硼化物空气多电子高容量电池
公开(公告)号：US09368846B2
公开(公告)日：2016-06-14
申请号：US13814904
申请日：2011-08-10
申请人： Stuart Licht
发明人： Stuart Licht
IPC分类号： H02J7/00 , H01M12/08 , H01M4/58 , H01M12/06 , B02C17/00 , B02C23/18 , H01M10/44
CPC分类号： H01M12/08 , B02C17/00 , B02C23/18 , H01M4/5825 , H01M10/44 , H01M12/06 , Y02E60/128
摘要： A battery and methods of forming vanadium boride nanoparticles of an anode within a battery, and a method for recharging an air battery. The battery comprises an anode and a cathode in electrochemical contact with each other through an electrically neutral ionic conductor (an electrolyte). The cathode may comprise a catalyst effective for the reduction of dissolved oxygen. An electrical discharge of the anode is performed via multiple electron oxidation of vanadium boride.
摘要翻译：一种电池和形成电池内阳极的硼化钒纳米颗粒的方法，以及一种对空气电池进行再充电的方法。电池包括通过电中性离子导体（电解质）彼此电化学接触的阳极和阴极。阴极可以包含有效降低溶解氧的催化剂。阳极的放电通过钒硼化物的多次电子氧化进行。

6. 发明申请

US20160051628A1 METHODS OF TREATING FGF21-ASSOCIATED DISORDERS 审中-公开
标题翻译：治疗FGF21相关疾病的方法
公开(公告)号：US20160051628A1
公开(公告)日：2016-02-25
申请号：US14676863
申请日：2015-04-02
申请人： Brian R. BOETTCHER , Andreas LOEW , Shari L. CAPLAN , Douglas S. DANIELS , Bernhard H. GEIERSTANGER , Norio HAMAMATSU , Stuart LICHT , Stephen Craig WELDON
发明人： Brian R. BOETTCHER , Andreas LOEW , Shari L. CAPLAN , Douglas S. DANIELS , Bernhard H. GEIERSTANGER , Norio HAMAMATSU , Stuart LICHT , Stephen Craig WELDON
IPC分类号： A61K38/18 , A61K47/48 , C07K14/50
CPC分类号： A61K38/1825 , A61K47/593 , A61K47/60 , C07K14/50 , C07K2319/00 , C07K2319/30 , C07K2319/31
摘要： The invention relates to the identification of new polypeptide and protein variants of fibroblast growth factor 21 (FGF21) that have improved pharmaceutical properties. Also disclosed are methods for treating FGF21-associated disorders, including metabolic conditions.
摘要翻译：本发明涉及具有改善的药物性质的成纤维细胞生长因子21（FGF21）的新多肽和蛋白质变体的鉴定。还公开了治疗FGF21相关疾病（包括代谢病症）的方法。

7. 发明授权

US06033343A Iron-based storage battery 失效
标题翻译：铁基蓄电池
公开(公告)号：US06033343A
公开(公告)日：2000-03-07
申请号：US72448
申请日：1998-05-05
申请人： Stuart Licht
发明人： Stuart Licht
IPC分类号： H01M4/36 , H01M4/58 , H01M8/22 , H01M4/02
CPC分类号： H01M4/521 , H01M4/36 , H01M4/52 , H01M4/58 , H01M4/5825 , H01M8/22 , H01M2300/0002 , H01M2300/0014 , H01M2300/0017 , H01M2300/0048 , H01M2300/0065
摘要： An electric storage battery having a solid phase Fe(VI) salt cathode. The anode may be any of a large variety of conventional anode materials capable of being oxidized. The cathode and anode are located in separate half-cells which are in electrochemcial contact trough an electrically neutral ionic conductor. Optionally means may be provided for impeding the transfer of chemically reactive species between the two half-cells. Also optionally gas separator means may be provided for preventing the build-up of oxygen, hydrogen and other gases.
摘要翻译：一种具有固相Fe（VI）盐阴极的蓄电池。阳极可以是能够被氧化的各种常规阳极材料中的任何一种。阴极和阳极位于通过电中性离子导体电化学接触的分开的半电池中。可选地，可提供用于阻止两个半电池之间的化学反应物质的转移的装置。还可以提供气体分离器装置，以防止氧气，氢气和其它气体的积聚。

8. 发明授权

US4828942A Polysulfide battery 失效
标题翻译：聚硫电池
公开(公告)号：US4828942A
公开(公告)日：1989-05-09
申请号：US90052
申请日：1987-08-27
申请人： Stuart Licht
发明人： Stuart Licht
IPC分类号： H01M4/36 , H01M8/18 , H01M10/36
CPC分类号： H01M4/36 , H01M10/36 , H01M8/188 , Y02E60/528
摘要： A half-cell of an electric storage cell comprises an electrocatalytic electrode immersed in an aqueous salt solution of potassium and/or other polysulfide anions in high concentration so that the sulfur species which may be electrochemically oxidized or reduced form substantial components of the solution (e.g. at least 20% by weight). Na.sup.+ and OH.sup.- salts which limit polysulfide solubility and/or solution stability are not added to the salt solution. Aqueous Ks.sub.x.sup.-2 in the storage cell contains up to 24.5 molal reducible sulfur at 25.degree. C., and up to 34.2 molal reducible sulfur in solution at 70.degree. C. This high faradaic capacity is readily accessible at high current density with minimal polarization losses.
摘要翻译：蓄电池的半电池包括以高浓度浸入钾和/或其它多硫化物阴离子的盐水溶液中的电催化电极，使得可被电化学氧化或还原的硫物质形成溶液的实质组分（例如至少20重量％）。不向盐溶液中加入限制多硫化物溶解度和/或溶液稳定性的Na +和OH-盐。储存池中的Ksx-2水溶液在25℃下含有最多24.5摩尔可还原的硫，在70℃溶液中含有高达34.2摩尔的可还原的硫。这种高法拉第容量容易在高电流密度下获得，极少的极化损失。

9. 发明授权

US09758881B2 Process for electrosynthesis of energetic molecules 有权
公开(公告)号：US09758881B2
公开(公告)日：2017-09-12
申请号：US12704748
申请日：2010-02-12
申请人： Stuart Licht
发明人： Stuart Licht
IPC分类号： B01J19/12 , C25B1/00 , C25B9/00
CPC分类号： C25B1/00 , B01J19/128 , C25B9/00 , Y02P20/134
摘要： A process for the production of energetically rich compounds comprising: using externally supplied thermal energy to heat an electrolyzable compound to a temperature greater than the ambient temperature; generating electricity from a solar electrical photovoltaic component; subjecting the heated electrolyzable compound to electrolysis with the solar generated electricity to generate an energetically rich electrolytic product.

10. 发明授权

US09683297B2 Apparatus for molten salt electrolysis with solar photovoltaic electricity supply and solar thermal heating of molten salt electrolyte 有权
公开(公告)号：US09683297B2
公开(公告)日：2017-06-20
申请号：US13606791
申请日：2012-09-07
申请人： Stuart Licht
发明人： Stuart Licht
IPC分类号： C25B1/00 , C25B9/00
CPC分类号： C25B1/00 , B01J19/128 , C25B9/00 , Y02P20/134
摘要： A process for the production of energetically rich compounds comprising: using externally supplied thermal energy to heat an electrolyzable compound to a temperature greater than the ambient temperature; generating electricity from a solar electrical photovoltaic component; subjecting the heated electrolyzable compound to electrolysis with the solar generated electricity to generate an energetically rich electrolytic product.

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