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1. 发明申请

US20220339451A1 Multisite Leadless Cardiac Resynchronization 有权
公开(公告)号：US20220339451A1
公开(公告)日：2022-10-27
申请号：US17728611
申请日：2022-04-25
申请人： Yoram PALTI , Rafael BEYAR
发明人： Yoram PALTI , Rafael BEYAR
IPC分类号： A61N1/368 , A61N1/362
摘要： Synchronized stimulation of cardiac tissue can be implemented by implanting two or more rectifier-based AM receivers into different positions within a subject's heart. Each receiver is tuned to a different frequency, and generates an output signal that is capable of stimulating cardiac tissue when a signal at the corresponding tuned frequency arrives at the receiver. An AM transmitter can activate any given one of the receivers by transmitting a signal into the subject's body at the proper frequency. A controller controls the transmitter by commanding the transmitter to transmit pulses of AC at different frequencies at different times, so that when those pulses are received by the correspondingly-tuned receivers, each of the receivers will generate respective output signals that stimulate respective parts of the heart at respective times to promote improved cardiac performance.

2. 发明申请

US20220023630A1 Apparatus for Strengthening Muscle Contraction (e.g., Cardiac Muscle Contraction) Using Electric Fields 有权
公开(公告)号：US20220023630A1
公开(公告)日：2022-01-27
申请号：US17378998
申请日：2021-07-19
申请人： Yoram PALTI , Rafael BEYAR
发明人： Yoram PALTI , Rafael BEYAR
IPC分类号： A61N1/362 , A61N1/365
摘要： An apparatus for improving the cardiac function and cardiac output of a patient comprises a waveform generator that generates alternating voltage pulses, a controller to control the timing of the pulses, and electrodes that deliver the alternating voltage pulses to the patient's body. The alternating voltage pulses induce a field of alternating current pulses within the patient's body. As the pulses pass through a cardiac ventricle (or atrium), they increase the concentration of Ca2+ at the appropriate cardiomyocyte sites, and thereby increase the strength and duration of the ventricular (or atrial) contractions. In alternative embodiments, the electric field may be used to strengthen the contractions of non-cardiac muscle (e.g., skeletal muscle).

3. 发明授权

US11197971B2 Nanotube-based humidification 有权
公开(公告)号：US11197971B2
公开(公告)日：2021-12-14
申请号：US16541436
申请日：2019-08-15
申请人： Yoram Palti
发明人： Yoram Palti
IPC分类号： A61M16/16 , A61M16/10 , F24F11/74 , F24F6/04 , F24F110/20 , F24F110/10
摘要： A humidifier uses a field of hydrophobic, nanotubes (e.g., vertically aligned carbon nanotubes) to humidify a gas. Voids in the field form liquid flow channels that are wide enough for liquid water to pass through. The nanotubes are spaced close enough to each other to prevent the water from escaping the channels. Water in the channels is absorbed by gas that flows and/or diffuses between the nanotubes. Humidity levels in the gas can be measured and controlled to a desired level by controlling the rate of flow of gas through the humidifier, controlling heating of the gas, and/or adjusting the total area of molecular transfer from the water to the gas by providing multiple banks of nanotubes and controlling the number of banks through which the gas flows.

4. 发明授权

US10780287B2 Retrofit to protect implanted devices (e.g., pacemakers) from unauthorized manipulation 有权
公开(公告)号：US10780287B2
公开(公告)日：2020-09-22
申请号：US16499287
申请日：2018-04-05
申请人： Yoram Palti
发明人： Yoram Palti
IPC分类号： A61N1/372 , A61N1/362 , A61N1/39 , A61N1/40 , H04W12/08
摘要： An implantable device that (a) has an analog input configured to detect analog electrical signals and (b) is configured to accept RF commands can be retrofitted to prevent unauthorized access by modifying the software of the implantable device to (1) accept control commands that arrive via the analog input and (2) ignore control commands that arrive via the RF transceiver. Ultrasound communications can then be detected and inductively coupled onto a lead that is connected to the analog input. In some embodiments, the modified implantable device can only be controlled via ultrasound signals at all times to improve security. In other embodiments, the modified implantable device can only be controlled via non-ultrasound signals (e.g., RF signals) for short periods of time after the system has been unlocked in response to receipt of a specific ultrasound signal.

5. 发明申请

US20200055001A1 Extracting/Introducing Molecules from/to Blood or Other Liquids 审中-公开
公开(公告)号：US20200055001A1
公开(公告)日：2020-02-20
申请号：US16543003
申请日：2019-08-16
申请人： Yoram PALTI
发明人： Yoram PALTI
IPC分类号： B01D69/08 , B01D71/02 , A01N1/02 , A61M1/16
摘要： A molecule can be removed from blood by passing the blood through channels that are surrounded by nanotubes with spaces therebetween. Each channel is wide enough for blood to flow through, and the nanotubes are spaced close enough to each other to retain the blood within the channels. Gas passing through the spaces between the nanotubes outside the channels comes into contact with the blood at the outer boundaries of the channels, and the molecule in the blood diffuses into the gas. In other embodiments, a molecule can be introduced into blood by passing the blood through channels that are surrounded by nanotubes with spaces therebetween. Gas that includes the molecule passes through the spaces between the nanotubes outside the channels. The gas comes into contact with the blood at the outer boundaries of the channels, and the molecule in the gas diffuses into the blood.

6. 发明申请

US20200054853A1 Nanotube-Based Humidification 审中-公开
公开(公告)号：US20200054853A1
公开(公告)日：2020-02-20
申请号：US16541436
申请日：2019-08-15
申请人： Yoram PALTI
发明人： Yoram PALTI
IPC分类号： A61M16/10 , F24F6/04 , F24F11/74
摘要： A humidifier uses a field of hydrophobic, nanotubes (e.g., vertically aligned carbon nanotubes) to humidify a gas. Voids in the field form liquid flow channels that are wide enough for liquid water to pass through. The nanotubes are spaced close enough to each other to prevent the water from escaping the channels. Water in the channels is absorbed by gas that flows and/or diffuses between the nanotubes. Humidity levels in the gas can be measured and controlled to a desired level by controlling the rate of flow of gas through the humidifier, controlling heating of the gas, and/or adjusting the total area of molecular transfer from the water to the gas by providing multiple banks of nanotubes and controlling the number of banks through which the gas flows.

7. 发明申请

US20200041486A1 Distributed Fluid-Flow Systems with Equalized Flow Rate 审中-公开
公开(公告)号：US20200041486A1
公开(公告)日：2020-02-06
申请号：US16529262
申请日：2019-08-01
申请人： Yoram PALTI
发明人： Yoram PALTI , Matan DISHON
IPC分类号： G01N33/50 , B01L3/00
摘要： Distributed liquid-flow systems—in which flow spreads out from a system inlet and traverses the system through multiple discrete, smaller flow channels—are constructed to minimize variations in flow-resistance-induced pressure drop from the system inlet to entrances to the flow channels. Because flow-driving pressure will be more uniform at the entrances to the flow channels, flow along the channels will be more uniform. Disclosed embodiments may be particularly suitable or advantageous for use in gas-exchange/artificial lung devices.

8. 发明授权

US09138522B2 Gas exchanger and artificial lung 有权
标题翻译：气体交换器和人造肺
公开(公告)号：US09138522B2
公开(公告)日：2015-09-22
申请号：US14331608
申请日：2014-07-15
申请人： Yoram Palti
发明人： Yoram Palti
IPC分类号： A61M1/16 , B01D69/04
CPC分类号： A61M1/1698 , A61M2202/0208 , A61M2202/0225 , B01D69/04
摘要： Blood or other fluids can be caused to interact with a gas by providing a plurality of fluid flow channels that are surrounded by nanotubes, each of the channels having an inflow end and an outflow end, wherein each of the channels is wide enough for the blood to flow through, and wherein the nanotubes are spaced close enough to each other to retain the fluid within the channels when the blood is flowing through the channels. The fluid is then passed through the through the channels while a gas is passed through the spaces between the nanotubes outside the fluid flow channels. This permits the gas to interact with the fluid in the channels.
摘要翻译：可以通过提供由纳米管围绕的多个流体流动通道使血液或其它流体与气体相互作用，每个通道具有流入端和流出端，其中每个通道足够宽以使血液流过，并且其中，当血液流过通道时，纳米管彼此间隔足够近以将流体保持在通道内。然后使流体通过通道，同时气体通过流体流动通道外的纳米管之间的空间。这允许气体与通道中的流体相互作用。

9. 发明申请

US20140275967A1 Method and Apparatus for Detecting a Dipole Position Marker 审中-公开
标题翻译：用于检测偶极位置标记的方法和装置
公开(公告)号：US20140275967A1
公开(公告)日：2014-09-18
申请号：US14179346
申请日：2014-02-12
申请人： Yoram Palti
发明人： Yoram Palti
IPC分类号： A61B8/08
CPC分类号： A61B8/0841 , A61B5/064 , A61B5/6861 , A61B8/4461 , A61B8/488 , A61B8/5261 , A61B90/39 , A61B2090/3925
摘要： An apparatus, method and system for detecting a position within a body are provided. A dipole that is free to rotate or oscillate within a capsule is inserted at a target location within the body. The dipole can be either electric or magnetic, and the dipole rotates or oscillates within the capsule when an alternating or rotating electric or magnetic field is applied in the vicinity of the dipole. Ultrasound energy is impinged upon the target location and a position of the dipole is determined based on detected ultrasound reflections.
摘要翻译：提供了一种用于检测身体内的位置的装置，方法和系统。在胶囊内自由旋转或振荡的偶极子插入到体内的目标位置。当在偶极子附近施加交替或旋转的电场或磁场时，偶极子可以是电的或磁的，并且偶极子在胶囊内旋转或振荡。超声能量撞击目标位置，并且基于检测到的超声反射来确定偶极子的位置。

10. 发明授权

US08447396B2 Treating bacteria with electric fields 有权
标题翻译：用电场处理细菌
公开(公告)号：US08447396B2
公开(公告)日：2013-05-21
申请号：US13428887
申请日：2012-03-23
申请人： Yoram Palti , Moshe Giladi
发明人： Yoram Palti , Moshe Giladi
IPC分类号： A61N1/18
CPC分类号： A61N1/326 , A61N1/40
摘要： Cells that are in the process division are vulnerable to damage by AC electric fields that have specific frequency and field strength characteristics. The selective destruction of rapidly dividing cells can therefore be accomplished by imposing an AC electric field in a target region for extended periods of time. Some of the cells that divide while the field is applied will be damaged, but the cells that do not divide will not be harmed. This selectively damages rapidly dividing cells like bacteria, but does not harm normal cells that are not dividing. Since the vulnerability of the dividing cells is strongly related to the alignment between the long axis of the dividing cells and the lines of force of the electric field, improved results can be obtained when the field is sequentially imposed in different directions.
摘要翻译：处于过程部分的电池容易受到具有特定频率和场强特性的交流电场的损害。因此，快速分裂细胞的选择性破坏可以通过在目标区域中长时间施加AC电场来实现。一些应用场地分割的细胞将被破坏，但不分裂的细胞不会受到伤害。这有选择地损害快速分裂的细胞，如细菌，但不会伤害不分裂的正常细胞。由于分割单元的脆弱性与分割单元的长轴与电场的力线之间的对准强烈相关，所以当场依次施加在不同的方向时，可以获得改进的结果。

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