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1. 发明授权

US09134431B2 Radiation detector 有权
标题翻译：辐射检测器
公开(公告)号：US09134431B2
公开(公告)日：2015-09-15
申请号：US13813658
申请日：2010-12-09
申请人： Takuto Sakumura , Yuji Tsuji , Pawel Grybos , Piotr Maj , Robert Szczygiel
发明人： Akira Tsukiyama , Takuto Sakumura , Yuji Tsuji , Pawel Grybos , Piotr Maj , Robert Szczygiel
IPC分类号： G01T1/24 , G01T1/16 , H04N5/32 , H04N5/378 , H04N5/335 , H04N5/374
CPC分类号： G01T1/16 , G01T1/247 , H04N5/32 , H04N5/335 , H04N5/374 , H04N5/378
摘要： A radiation detector 100 has a plurality of single-photon-counting imaging cells, including an imaging cell 1 configured to generate a detection signal in accordance with the intensity of radiation, a digitization circuit 5 configured to digitize the detection signal, a data read structure 11 configured to count the digitized detection signal and to keep the result as a data bit, and a send-out register 13 configured to control the input of a predetermined data bit output from the data read structure 11 by a data shift in accordance with a first clock Pck, to keep the input data bit as a result of the control, and to send out the kept data bit by a data shift in accordance with a second clock Sck.
摘要翻译：辐射检测器100具有多个单光子计数成像单元，包括被配置为根据辐射强度产生检测信号的成像单元1，被配置为使检测信号数字化的数字化电路5，数据读取结构 11，被配置为对数字化检测信号进行计数并将结果保持为数据位，发送寄存器13被配置为通过数据移位来控制从数据读取结构11输出的预定数据位的输入第一时钟Pck，以将输入数据位保持为控制的结果，并且根据第二时钟Sck将保持的数据位发送出数据移位。

2. 发明申请

US20140203182A1 RADIATION DETECTOR 有权
标题翻译：辐射探测器
公开(公告)号：US20140203182A1
公开(公告)日：2014-07-24
申请号：US13813711
申请日：2010-12-09
申请人： Akira Tsukiyama , Takuto Sakumura , Yuji Tsuji , Pawel Grybos , Piotr Maj , Robert Szczygiel
发明人： Akira Tsukiyama , Takuto Sakumura , Yuji Tsuji , Pawel Grybos , Piotr Maj , Robert Szczygiel
IPC分类号： G01T1/24
CPC分类号： G01T1/247 , G01T1/17 , H04N5/32
摘要： There is provided a radiation detector that appropriately corrects an offset within a minute read cell without increasing area while achieving high-speed measurement at a high counting rate. A radiation detector 100 having a plurality of single-photon-counting imaging cells includes, for each imaging cell, a photodiode 3 which is applied with a reverse bias voltage and generates a current signal in response to incidence of radiation, a previous-stage DA converter d1 configured to correct an input signal based on the current signal generated by the photodiode 3, an amplifier k2 configured to amplify the signal corrected by the previous-stage DA converter d1, a subsequent-stage DA converter d2 configured to correct a charge signal amplified by the amplifier k2, a wave height discriminator 9 configured to discriminate output signals based on the signal corrected by the subsequent-stage DA converter d2, and a counter 10 configured to count the discriminated signals.
摘要翻译：提供了一种辐射检测器，其在不增加面积的情况下适当地校正分钟读取单元内的偏移量，同时以高计数率实现高速测量。具有多个单光子计数成像单元的放射线检测器100包括针对每个成像单元的光电二极管3，该光电二极管3被施加反向偏置电压并响应于辐射的入射而产生电流信号，前级DA 转换器d1，被配置为基于由光电二极管3产生的电流信号来校正输入信号;放大器k2，被配置为放大由前一级DA转换器d1校正的信号;后级DA转换器d2，被配置为校正电荷信号由放大器k2放大的波形鉴别器9，被配置为基于由后级DA转换器d2校正的信号来鉴别输出信号的波高鉴别器9以及被配置为对鉴别信号进行计数的计数器10。

3. 发明申请

US20140131588A1 RADIATION DETECTOR 有权
标题翻译：辐射探测器
公开(公告)号：US20140131588A1
公开(公告)日：2014-05-15
申请号：US13813658
申请日：2010-12-09
申请人： Akira Tsukiyama , Takuto Sakumura , Yuji Tsuji , Pawel Grybos , Piotr Maj , Robert Szczygiel
发明人： Akira Tsukiyama , Takuto Sakumura , Yuji Tsuji , Pawel Grybos , Piotr Maj , Robert Szczygiel
IPC分类号： G01T1/16
CPC分类号： G01T1/16 , G01T1/247 , H04N5/32 , H04N5/335 , H04N5/374 , H04N5/378
摘要： There is provided a radiation detector which shortens the data read time to outside in accordance with the necessity to increase the frame rate. A radiation detector 100 having a plurality of single-photon-counting imaging cells, including an imaging cell 1 configured to generate a detection signal in accordance with the intensity of radiation, a digitization circuit 5 configured to digitize the detection signal, a data read structure 11 configured to count the digitized detection signal and to keep the result as a data bit, and a send-out register 13 configured to control the input of a predetermined data bit output from the data read structure 11 by a data shift in accordance with a first clock Pck, to keep the input data bit as a result of the control, and to send out the kept data bit by a data shift in accordance with a second clock Sck.
摘要翻译：提供了一种根据增加帧速率的必要性将数据读取时间缩短到外部的辐射检测器。具有多个单光子计数成像单元的放射线检测器100，包括被配置为根据辐射强度生成检测信号的成像单元1，被配置为使检测信号数字化的数字化电路5，数据读取结构 11，被配置为对数字化检测信号进行计数并将结果保持为数据位，发送寄存器13被配置为通过数据移位来控制从数据读取结构11输出的预定数据位的输入第一时钟Pck，以将输入数据位保持为控制的结果，并且根据第二时钟Sck将保持的数据位发送出数据移位。

4. 发明申请

US20120161027A1 X-RAY DETECTOR 审中-公开
标题翻译： X射线探测器
公开(公告)号：US20120161027A1
公开(公告)日：2012-06-28
申请号：US13337959
申请日：2011-12-27
申请人： Akira TSUKIYAMA , Takuto SAKUMURA , Yuji TSUJI
发明人： Akira TSUKIYAMA , Takuto SAKUMURA , Yuji TSUJI
IPC分类号： G01T1/17
CPC分类号： G01T1/2928 , G01T1/243 , G01T1/247 , G01T1/2985 , H04N5/32
摘要： An X-ray detector is connected to a large number of detector modules connected in series. The X-ray detector detects X-ray image data for each detection module, each module synchronously reading X-ray image data detected by itself based on an internal clock φ, each module transferring the read X-ray image data one after another. Each of the detection modules receives the transferred X-ray image data, and resynchronizes the received X-ray image data by using the internal clock, and transfers the same together with the detected X-ray image data. This enables arranging the detection module at an arbitrary position without a change in the method of transferring data for each measurement or without a load on a control device.
摘要翻译： X射线检测器连接到大量串联的检测器模块。 X射线检测器检测每个检测模块的X射线图像数据，每个模块基于内部时钟＆phgr同步地读取其自身检测的X射线图像数据;每个模块一个接一个地传送读取的X射线图像数据。每个检测模块接收所传送的X射线图像数据，并且通过使用内部时钟重新同步所接收的X射线图像数据，并将其与检测到的X射线图像数据一起传送。这使得能够将检测模块布置在任意位置，而不会改变用于每次测量的数据的传送方式或在控制装置上没有负载。

5. 发明申请

US20110317813A1 WAVELENGTH-CLASSIFYING TYPE X-RAY DIFFRACTION DEVICE 有权
标题翻译：波长分类型X射线衍射装置
公开(公告)号：US20110317813A1
公开(公告)日：2011-12-29
申请号：US13170708
申请日：2011-06-28
申请人： Kazuyuki MATSUSHITA , Takuto Sakumura , Yuji Tsuji , Masataka Maeyama , Kimiko Hasegawa
发明人： Kazuyuki MATSUSHITA , Takuto Sakumura , Yuji Tsuji , Masataka Maeyama , Kimiko Hasegawa
IPC分类号： G01N23/207 , G01N23/20
CPC分类号： H01J35/10 , G01N23/207 , H01J2235/081 , H01J2235/086
摘要： A wavelength-classifying type X-ray diffraction device bombards a sample with characteristic X-rays generated from an X-ray generation source, and detects characteristic X-rays diffracted by the sample using an X-ray detector. The X-ray generation source is composed of several metals of different atomic number, respective metals generating several characteristic X-rays of different wavelengths. An X-ray detector is composed of several pixels for receiving X-rays and outputting pulse signals corresponding to X-ray wavelengths. Pixels are respectively furnished with classification circuits. The classification circuits classify and output pixel output signals based on each of characteristic X-ray wavelengths. X-ray intensity is detected on a per-wavelength basis in individual pixels 12. Measurement data based on different wavelength X-rays are acquired simultaneously in just one measurement. Data of diffracted X-rays of different wavelengths are acquired using the entire region of the receiving surface of a two-dimensional detector.
摘要翻译：波长分类型X射线衍射装置用X射线产生源产生的特征X射线轰击样品，并使用X射线检测器检测由样品衍射的特征X射线。 X射线产生源由不同原子数的几种金属组成，各种金属产生不同波长的几种特征X射线。 X射线检测器由用于接收X射线的几个像素组成并且输出对应于X射线波长的脉冲信号。像素分别配有分类电路。分类电路基于每个特征X射线波长对像素输出信号进行分类和输出。在单个像素12中以每个波长为基础检测X射线强度。仅在一个测量中同时获取基于不同波长X射线的测量数据。使用二维检测器的接收表面的整个区域获取不同波长的衍射X射线的数据。

6. 发明申请

US20120161019A1 X-RAY DETECTOR 有权
标题翻译： X射线探测器
公开(公告)号：US20120161019A1
公开(公告)日：2012-06-28
申请号：US13337859
申请日：2011-12-27
申请人： Yuji TSUJI , Takuto SAKUMURA , Shinnichi OHYA , Akira TSUKIYAMA
发明人： Yuji TSUJI , Takuto SAKUMURA , Shinnichi OHYA , Akira TSUKIYAMA
IPC分类号： G01T1/24
CPC分类号： H01L27/14658 , H01L27/14618 , H01L31/0201 , H01L31/0203 , H01L2924/0002 , H01L2924/00
摘要： To provide an X-ray detector facilitating the installing and replacement work of a module while reducing the possibility of breakage. An X-ray detector 50 detecting X-ray image data for each detection module includes: a detection module 7 provided with a protruding frame on aback side of a detection device detecting X-rays; and a guide frame 12 fitting into the protruding frame and removably supporting the detection device, wherein the guide frame 12 fixes the position of the detection device relative to the guide frame 12 by fitting. Therefore, fitting the protruding frame 8 into the guide frame 12 enables precise and easy installation/removal of the detection module. That is a detection module can be newly installed onto the guide frame without interfering each other with adjacent detection modules already installed while minimizing a space therebetween.
摘要翻译：提供X射线检测器，便于模块的安装和更换工作，同时减少破损的可能性。用于检测每个检测模块的X射线图像数据的X射线检测器50包括：检测模块7，其在检测X射线的检测装置的侧面设置有突出框架; 以及引导框架12，其配合到突出框架中并可移除地支撑检测装置，其中引导框架12通过装配固定检测装置相对于引导框架12的位置。因此，将突出框架8装配到引导框架12中能够精确且容易地安装/移除检测模块。这是一种检测模块可以新安装到引导框架上，而不会相互干扰，同时已经安装了相邻的检测模块，同时最小化了它们之间的空间。

7. 发明授权

US08039248B2 Modified flavin adenine dinucleotide dependent glucose dehydrogenase 有权
标题翻译：改良黄素腺嘌呤二核苷酸依赖性葡萄糖脱氢酶
公开(公告)号：US08039248B2
公开(公告)日：2011-10-18
申请号：US12547276
申请日：2009-08-25
申请人： Hiroshi Kawaminami , Yuji Tsuji , Masao Kitabayashi , Yoshiaki Nishiya
发明人： Hiroshi Kawaminami , Yuji Tsuji , Masao Kitabayashi , Yoshiaki Nishiya
IPC分类号： C12M1/34 , C12Q1/54 , C12Q1/52 , C12N9/04 , C12N9/24
CPC分类号： C12N9/0006
摘要： The invention provides a modified flavin adenine dinucleotide dependent glucose dehydrogenase (FADGDH), as well as a glucose sensor comprising the modified FADGDH and a method for measuring glucose comprising using the glucose sensor to measure glucose of a sample.
摘要翻译：本发明提供了修饰的黄素腺嘌呤二核苷酸依赖性葡萄糖脱氢酶（FADGDH），以及包含修饰的FADGDH的葡萄糖传感器和测量葡萄糖的方法，包括使用葡萄糖传感器测量样品的葡萄糖。

8. 发明申请

US20110000312A1 FLOW MEASURING DEVICE 有权
标题翻译：流量测量装置
公开(公告)号：US20110000312A1
公开(公告)日：2011-01-06
申请号：US12712898
申请日：2010-02-25
申请人： Naotsugu Ueda , Katsuyuki Yamamoto , Shuji Maeda , Yuji Tsuji
发明人： Naotsugu Ueda , Katsuyuki Yamamoto , Shuji Maeda , Yuji Tsuji
IPC分类号： G01F1/42
CPC分类号： G01F15/185 , G01F1/42 , G01F1/684 , G01F1/6842 , G01F1/6845 , G01F5/005
摘要： A flow measuring device has a flow channel block including a main flow channel whose both ends are open, and an auxiliary flow channel that branches from the main flow channel, a flow amount measurement element provided for the auxiliary flow channel, and a branch entrance and a collection exit that open in a wall surface of the main flow channel, and that communicate to the auxiliary flow channel, so that a part of a gaseous body that flows through the main flow channel is directed to the auxiliary flow channel through the branch entrance, and the gaseous body that has passed through the auxiliary flow channel is directed back to the main flow channel through the collection exit. A holding member containing portion is provided in a depressed manner for an area excluding an area including the branch entrance and an area including the collection exit in a circumference surface of a space of the flow channel block that configures the main flow channel. An orifice is contained within the main flow channel. An orifice holding member fitted into the holding member containing portion holds the orifice by being brought into contact with the orifice. The wall surface of the main flow channel is configured by a wall surface excluding the area for which the holding member containing portion is formed out of the main flow channel and an inner surface of the orifice holding member.
摘要翻译：流量测量装置具有流路块，其包括两端开放的主流路和从主流路分支的辅流流路，为辅助流路设置的流量测量元件和分支入口，收集出口，其在主流动通道的壁表面中开口，并且与辅助流动通道连通，使得流过主流动通道的气体的一部分通过分支入口被引导到辅助流动通道并且已经通过辅助流动通道的气体通过收集出口返回到主流动通道。在构成主流路的流路块的空间的周面上，以凹陷的方式设置保持构件容纳部，用于除了包括分支入口的区域的区域和包括收集口的区域。主流道内装有孔口。装配到保持构件容纳部分中的孔口保持构件通过与孔口接触而保持孔口。主流路的壁面由除了从主流路形成保持部件容纳部的区域和孔保持部件的内表面以外的壁面构成。

9. 发明申请

US20090317848A1 MODIFIED FLAVIN ADENINE DINUCLEOTIDE DEPENDENT GLUCOSE DEHYDROGENASE 有权
标题翻译：改性FLAVIN ADENINE DINUCLEOTIDE依赖性葡萄糖脱氢酶
公开(公告)号：US20090317848A1
公开(公告)日：2009-12-24
申请号：US12547276
申请日：2009-08-25
申请人： Hiroshi KAWAMINAMI , Yuji TSUJI , Masao KITABAYASHI , Yoshiaki NISHIYA
发明人： Hiroshi KAWAMINAMI , Yuji TSUJI , Masao KITABAYASHI , Yoshiaki NISHIYA
IPC分类号： C12Q1/54 , C12M1/34
CPC分类号： C12N9/0006
摘要： The invention provides a modified flavin adenine dinucleotide dependent glucose dehydrogenase (FADGDH), as well as a glucose sensor comprising the modified FADGDH and a method for measuring glucose comprising using the glucose sensor to measure glucose of a sample
摘要翻译：本发明提供了修饰的黄素腺嘌呤二核苷酸依赖性葡萄糖脱氢酶（FADGDH），以及包含修饰的FADGDH的葡萄糖传感器和测量葡萄糖的方法，包括使用葡萄糖传感器测量样品的葡萄糖

10. 发明申请

US20090259024A1 GLUCOSE DEHYDROGENASE FROM ASPERGILLUS ORYZAE 有权
标题翻译：来自ASPERGILLUS ORYZAE的GLUCOSE DEHYDROGENASE
公开(公告)号：US20090259024A1
公开(公告)日：2009-10-15
申请号：US12467407
申请日：2009-05-18
申请人： Yuji TSUJI , Masao KITABAYASHI , Takahide KISHIMOTO , Yoshiaki NISHIYA
发明人： Yuji TSUJI , Masao KITABAYASHI , Takahide KISHIMOTO , Yoshiaki NISHIYA
IPC分类号： C07K14/38
CPC分类号： C12N9/0006
摘要： The present invention effectively produces glucose dehydrogenase derived from Aspergillus oryzae, and provides more practical glucose dehydrogenase. The invention makes it possible to efficiently produce glucose dehydrogenase and to obtain glucose dehydrogenase in more practical manner by using a glucose dehydrogenase gene isolated from Aspergillus oryzae.
摘要翻译：本发明有效地产生源自米曲霉的葡萄糖脱氢酶，提供更实用的葡萄糖脱氢酶。通过使用从米曲霉分离的葡萄糖脱氢酶基因，本发明能够以更实用的方式有效地产生葡萄糖脱氢酶并获得葡萄糖脱氢酶。

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