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1. 发明授权

US09597029B2 System and method for remotely evaluating patient compliance status 有权
公开(公告)号：US09597029B2
公开(公告)日：2017-03-21
申请号：US11820798
申请日：2007-06-19
申请人： Abhilash Patangay , Shelley Marie Cazares
发明人： Abhilash Patangay , Shelley Marie Cazares
IPC分类号： A61B5/00 , G06F19/00 , A61N1/00 , A61B5/16 , A61N1/372
CPC分类号： A61B5/16 , A61B5/0002 , A61B5/165 , A61B5/4833 , A61B5/686 , A61B5/74 , A61N1/372 , G06F19/00 , G06F19/34 , G06F19/3418 , G06F19/3475
摘要： A system and method for remotely evaluating patient compliance status is presented. Compliance to a course of treatment is periodically checked through qualitative inquiry of a patient under remote management. Physiometry of the patient, that indicates emotional state, is remotely monitored contemporaneously with the qualitative state. Patient status is evaluated, including at least one of corroborating the compliance and identifying an emotional imbalance, based upon the indicated emotional state of the patient.

2. 发明申请

US20080319272A1 System and method for remotely evaluating patient compliance status 有权
标题翻译：用于远程评估患者依从性状态的系统和方法
公开(公告)号：US20080319272A1
公开(公告)日：2008-12-25
申请号：US11820798
申请日：2007-06-19
申请人： Abhilash Patangay , Shelley Marie Cazares
发明人： Abhilash Patangay , Shelley Marie Cazares
IPC分类号： A61B5/00
CPC分类号： A61B5/16 , A61B5/0002 , A61B5/165 , A61B5/4833 , A61B5/686 , A61B5/74 , A61N1/372 , G06F19/00 , G06F19/34 , G06F19/3418 , G06F19/3475
摘要： A system and method for remotely evaluating patient compliance status is presented. Compliance to a course of treatment is periodically checked through qualitative inquiry of a patient under remote management. Physiometry of the patient, that indicates emotional state, is remotely monitored contemporaneously with the qualitative state. Patient status is evaluated, including at least one of corroborating the compliance and identifying an emotional imbalance, based upon the indicated emotional state of the patient.
摘要翻译：提出了一种用于远程评估患者依从性状态的系统和方法。通过对远程管理患者的定性查询，定期检查对治疗过程的依从性。患者的物理测量，指示情绪状态，与定性状态同时进行远程监测。评估患者状态，包括至少一个根据患者指示的情绪状态证实依从性和识别情绪不平衡。

3. 发明授权

US07941208B2 Therapy delivery for identified tachyarrhythmia episode types 有权
标题翻译：治疗确定快速性心律失常发作类型
公开(公告)号：US07941208B2
公开(公告)日：2011-05-10
申请号：US11715128
申请日：2007-03-07
申请人： William H. Sauer , Shelley Marie Cazares , Dan Li
发明人： William H. Sauer , Shelley Marie Cazares , Dan Li
IPC分类号： A61B5/04
CPC分类号： A61N1/3622 , A61N1/3627
摘要： Methods and systems for identifying tachyarrhythmia episode types and delivering therapy to mitigate the identified tachyarrhythmia episode types are described. Electrogram signals of cardiac activity are sensed and stored by an implantable cardiac device. Tachyarrhythmia episodes are detected and tachyarrhythmia episode types are identified based on characteristics of the electrogram signals. In preparation for performing ablation, a tachyarrhythmia episode is induced. The features of the induced tachyarrhythmia episode are compared to characteristics of the identified episode types. A similarity between the induced tachyarrhythmia episode and at least one of the episode types identified from the stored electrogram signals is indicated to facilitate performing the ablation.
摘要翻译：描述了用于鉴定快速性心律失常发作类型并递送治疗以减轻所鉴定的快速性心律失常发作类型的方法和系统。心脏活动的电图信号由可植入的心脏装置感测和储存。检测到快速性心律失常发作，并根据电描记图信号的特征识别快速性心律失常发作类型。为准备进行消融，诱发快速性心律失常发作。将诱发的快速性心律失常发作的特征与鉴定的发作类型的特征进行比较。指示诱导的快速性心律失常发作与从存储的电描记图信号识别的至少一种发作类型之间的相似性，以便于进行消融。

4. 发明申请

US20100211126A1 Cardiac Tachyarrhythmia Therapy Selection Based on Patient Response Information 有权
标题翻译：基于患者反应信息的心脏快速性心律失常治疗选择
公开(公告)号：US20100211126A1
公开(公告)日：2010-08-19
申请号：US12771691
申请日：2010-04-30
申请人： Shelley Marie Cazares
发明人： Shelley Marie Cazares
IPC分类号： A61N1/365 , A61N1/39
CPC分类号： A61N1/3925 , A61B5/04525 , A61B5/046 , A61B5/0464 , A61N1/3622 , A61N1/365 , A61N1/3962
摘要： Cardiac treatment methods and devices providing templates representative of past tachyarrhythmia events, each template associated with a therapy. A cardiac waveform is detected, and if it corresponds to a particular template associated with a previous therapy that was satisfactory in terminating a past event, the previous therapy is delivered again. If unsatisfactory, the previous therapy is eliminated as an option. If, for example, the previous therapy was an antitachycardia pacing therapy unsatisfactory in terminating the past tachyarrhythmia event, delivery of the antitachycardia pacing therapy is eliminated as an option. Instead of ATP therapy, one or more of a cardioversion, defibrillation, or alternate anti-tachycardia pacing therapy may be associated with the particular template. Cardiac waveforms and templates may correspond in terms of one or more of morphology, timing, drug regimen, medication, neural activity, patient activity, hemodynamic status, cardiac tissue impedance, transthoracic impedance, or other information corresponding to the episode.
摘要翻译：提供代表过去快速性心律失常事件的模板的心脏治疗方法和装置，每种模板与治疗相关联。检测到心脏波形，并且如果它对应于与先前疗法相关联的特定模板，其在终止过去事件时令人满意，则再次传送先前的治疗。如果不满意，以前的治疗作为一种选择被消除。例如，如果以前的治疗是抗心动过速起搏治疗在终止过去的快速性心律失常事件中不令人满意，则作为选择消除了抗心动过速起搏疗法的输送。代替ATP治疗，可以将一种或多种心脏复律，除颤或替代的抗心动过速起搏治疗与特定模板相关联。心脏波形和模板可以对应于形态，时间，药物方案，药物，神经活动，患者活动，血液动力学状态，心脏组织阻抗，经胸阻抗或对应于该发作的其他信息中的一种或多种。

5. 发明授权

US07725184B2 Cardiac tachyarrhythmia therapy selection based on patient response information 失效
标题翻译：基于患者反应信息的心脏快速性心律失常治疗选择
公开(公告)号：US07725184B2
公开(公告)日：2010-05-25
申请号：US11807696
申请日：2007-05-30
申请人： Shelley Marie Cazares
发明人： Shelley Marie Cazares
IPC分类号： A61N1/362
CPC分类号： A61N1/3925 , A61B5/04525 , A61B5/046 , A61B5/0464 , A61N1/3622 , A61N1/365 , A61N1/3962
摘要： Cardiac treatment methods and devices providing templates representative of past tachyarrhythmia events, each template associated with a therapy. A cardiac waveform is detected, and if it corresponds to a particular template associated with a previous therapy that was satisfactory in terminating a past event, the previous therapy is delivered again. If unsatisfactory, the previous therapy is eliminated as an option. If, for example, the previous therapy was an antitachycardia pacing therapy unsatisfactory in terminating the past tachyarrhythmia event, delivery of the antitachycardia pacing therapy is eliminated as an option. Instead of ATP therapy, one or more of a cardioversion, defibrillation, or alternate anti-tachycardia pacing therapy may be associated with the particular template. Cardiac waveforms and templates may correspond in terms of one or more of morphology, timing, drug regimen, medication, neural activity, patient activity, hemodynamic status, cardiac tissue impedance, transthoracic impedance, or other information corresponding to the episode.
摘要翻译：提供代表过去快速性心律失常事件的模板的心脏治疗方法和装置，每种模板与治疗相关联。检测到心脏波形，并且如果它对应于与先前疗法相关联的特定模板，其在终止过去事件时令人满意，则再次传送先前的治疗。如果不满意，以前的治疗作为一种选择被消除。例如，如果以前的治疗是抗心动过速起搏治疗在终止过去的快速性心律失常事件中不令人满意，则作为选择消除了抗心动过速起搏疗法的输送。代替ATP治疗，可以将一种或多种心脏复律，除颤或替代的抗心动过速起搏治疗与特定模板相关联。心脏波形和模板可以对应于形态，时间，药物方案，药物，神经活动，患者活动，血液动力学状态，心脏组织阻抗，经胸阻抗或对应于该发作的其他信息中的一种或多种。

6. 发明申请

US20080125824A1 Therapy delivery for identified tachyarrhythmia episode types 有权
标题翻译：治疗确定快速性心律失常发作类型
公开(公告)号：US20080125824A1
公开(公告)日：2008-05-29
申请号：US11715128
申请日：2007-03-07
申请人： William H. Sauer , Shelley Marie Cazares , Dan Li
发明人： William H. Sauer , Shelley Marie Cazares , Dan Li
IPC分类号： A61N1/36
CPC分类号： A61N1/3622 , A61N1/3627
摘要： Methods and systems for identifying tachyarrhythmia episode types and delivering therapy to mitigate the identified tachyarrhythmia episode types are described. Electrogram signals of cardiac activity are sensed and stored by an implantable cardiac device. Tachyarrhythmia episodes are detected and tachyarrhythmia episode types are identified based on characteristics of the electrogram signals. In preparation for performing ablation, a tachyarrhythmia episode is induced. The features of the induced tachyarrhythmia episode are compared to characteristics of the identified episode types. A similarity between the induced tachyarrhythmia episode and at least one of the episode types identified from the stored electrogram signals is indicated to facilitate performing the ablation.
摘要翻译：描述了用于鉴定快速性心律失常发作类型并递送治疗以减轻所鉴定的快速性心律失常发作类型的方法和系统。心脏活动的电图信号由可植入的心脏装置感测和储存。检测到快速性心律失常发作，并根据电描记图信号的特征识别快速性心律失常发作类型。为准备进行消融，诱发快速性心律失常发作。将诱发的快速性心律失常发作的特征与鉴定的发作类型的特征进行比较。指示诱导的快速性心律失常发作与从存储的电描记图信号识别的至少一种发作类型之间的相似性，以便于进行消融。

7. 发明授权

US07933651B2 Cardiac template generation based on patient response information 失效
标题翻译：基于患者应答信息的心脏模板生成
公开(公告)号：US07933651B2
公开(公告)日：2011-04-26
申请号：US10995704
申请日：2004-11-23
申请人： Shelley Marie Cazares , Yayun Lin , Alok S. Sathaye
发明人： Shelley Marie Cazares , Yayun Lin , Alok S. Sathaye
IPC分类号： A61B5/0452
CPC分类号： A61B5/042 , A61N1/3702 , A61N1/3925
摘要： Cardiac treatment methods and devices provide for templates representative of past tachyarrhythmia events, each template associated with a therapy. Methods involve providing a cardiac waveform representative of a patient's cardiac activity and identifying a portion that indicates an arrhythmic event. A cardiac template corresponding to the portion is generated, and a therapy is associated with the template useful for treating a subsequent arrhythmia. The waveform portion may be identified by a physician using a patient-external device to display the cardiac waveform. The template may be generated by a physician selecting the cardiac waveform, and determining if the therapy associated with the template was satisfactory and/or effective in treating the arrhythmia. Identification may involve matching the event to templates generated using cardiac waveforms other than the patient's cardiac waveforms. The template may be generated in a patient-internal or patient-external medical device such as a programmer, and/or an advanced patient management system.
摘要翻译：心脏治疗方法和装置提供代表过去快速性心律失常事件的模板，每个模板与治疗相关联。方法包括提供代表患者心脏活动的心脏波形并识别指示心律失常事件的部分。产生对应于该部分的心脏模板，并且与可用于治疗随后的心律失常的模板相关联的治疗。波形部分可以由医师使用患者外部设备来识别，以显示心脏波形。模板可以由医师选择心脏波形产生，并且确定与模板相关联的治疗是否令人满意和/或有效地治疗心律失常。识别可能涉及将事件与使用除患者心脏波形之外的心脏波形产生的模板进行匹配。模板可以在诸如程序员和/或高级患者管理系统的患者内部或患者外部医疗设备中生成。

8. 发明申请

US20090312813A1 Method and Device for Determination of Arrhythmia Rate Zone Thresholds 有权
标题翻译：用于确定心律失常率区域阈值的方法和装置
公开(公告)号：US20090312813A1
公开(公告)日：2009-12-17
申请号：US12545364
申请日：2009-08-21
申请人： Shelley Marie Cazares , Carlos Alberto Ricci , Jaeho Kim
发明人： Shelley Marie Cazares , Carlos Alberto Ricci , Jaeho Kim
IPC分类号： A61N1/365
CPC分类号： A61B5/0464 , A61N1/3925 , A61N1/3962
摘要： Approaches for determining threshold values for one or more arrhythmia rate zones and/or the number of rate zones are described. A probability function for heart rate is determined using collected and measured heart rate values. One or more heart rate probability values are selected. Thresholds for arrhythmia rate zones are determined from the probability function based on the selected probability values. Determining the rate zone thresholds may involve determining a threshold for a lower rate limit and/or determining one or more tachyarrhythmia rate zone thresholds. The number of rate zones may also be determined based on the probability function.
摘要翻译：描述了用于确定一个或多个心律失常率区域的阈值和/或速率区域的数量的方法。使用收集和测量的心率值来确定心率的概率函数。选择一个或多个心率概率值。基于所选择的概率值，从概率函数确定心律失常率区域的阈值。确定速率区阈值可以包括确定较低速率限制的阈值和/或确定一个或多个快速性心律失常率区域阈值。速率区域的数量也可以基于概率函数来确定。

9. 发明申请

US20110218449A1 Therapy Delivery for Identified Tachyarrhythmia Episode Types 有权
标题翻译：治疗快速性心律失常发作类型
公开(公告)号：US20110218449A1
公开(公告)日：2011-09-08
申请号：US13104439
申请日：2011-05-10
申请人： William H. Sauer , Shelley Marie Cazares , Dan Li
发明人： William H. Sauer , Shelley Marie Cazares , Dan Li
IPC分类号： A61B5/0464
CPC分类号： A61N1/3622 , A61N1/3627
摘要： Methods and systems for identifying tachyarrhythmia episode types and delivering therapy to mitigate the identified tachyarrhythmia episode types are described. Electrogram signals of cardiac activity are sensed and stored by an implantable cardiac device. Tachyarrhythmia episodes are detected and tachyarrhythmia episode types are identified based on characteristics of the electrogram signals. In preparation for performing ablation, a tachyarrhythmia episode is induced. The features of the induced tachyarrhythmia episode are compared to characteristics of the identified episode types. A similarity between the induced tachyarrhythmia episode and at least one of the episode types identified from the stored electrogram signals is indicated to facilitate performing the ablation.
摘要翻译：描述了用于鉴定快速性心律失常发作类型并递送治疗以减轻所鉴定的快速性心律失常发作类型的方法和系统。心脏活动的电图信号由可植入的心脏装置感测和储存。检测到快速性心律失常发作，并根据电描记图信号的特征识别快速性心律失常发作类型。为准备进行消融，诱发快速性心律失常发作。将诱发的快速性心律失常发作的特征与鉴定的发作类型的特征进行比较。指示诱导的快速性心律失常发作与从存储的电描记图信号识别的至少一种发作类型之间的相似性，以便于进行消融。

10. 发明授权

US07580741B2 Method and device for determination of arrhythmia rate zone thresholds using a probability function 有权
标题翻译：使用概率函数确定心律失常率阈值阈值的方法和装置
公开(公告)号：US07580741B2
公开(公告)日：2009-08-25
申请号：US11506253
申请日：2006-08-18
申请人： Shelley Marie Cazares , Carlos Alberto Ricci , Jaeho Kim
发明人： Shelley Marie Cazares , Carlos Alberto Ricci , Jaeho Kim
IPC分类号： A61B5/04
CPC分类号： A61B5/0464 , A61N1/3925 , A61N1/3962
摘要： A probability function for heart rate is determined using collected and measured heart rate values. One or more heart rate probability values are selected. Thresholds for arrhythmia rate zones are determined from the probability function based on the selected probability values. Determining the rate zone thresholds may involve determining a threshold for a lower 15 rate limit and/or determining one or more tachyarrhythmia rate zone thresholds. The number of rate zones may also be determined based on the probability function.
摘要翻译：使用收集和测量的心率值来确定心率的概率函数。选择一个或多个心率概率值。基于所选择的概率值，从概率函数确定心律失常率区域的阈值。确定速率区域阈值可以包括确定较低的15个速率限制的阈值和/或确定一个或多个快速性心律失常率区域阈值。速率区域的数量也可以基于概率函数来确定。

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