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1. 发明申请

US20170120056A1 IMPLANTABLE PULSE GENERATOR HAVING CURRENT STEERING MEANS 审中-公开
公开(公告)号：US20170120056A1
公开(公告)日：2017-05-04
申请号：US15172317
申请日：2016-06-03
申请人： Boston Scientific Neuromodulation Corporation
发明人： Carla Mann Woods , David K.L. Peterson , Paul M. Meadows , Gerald E. Loeb
IPC分类号： A61N1/36 , A61N1/372 , A61N1/05
CPC分类号： A61N1/36185 , A61N1/0551 , A61N1/0553 , A61N1/36071 , A61N1/37235 , A61N1/37247
摘要： An implantable pulse generator includes a current steering capability that allows a clinician or patient to quickly determine a desired electrode stimulation pattern, including which electrodes of a group of electrodes within an electrode array should receive a stimulation current, including the amplitude, width and pulse repetition rate of such current. Movement of the selected group of electrodes is facilitated through the use of remotely generated directional signals, generated by a pointing device, such as a joystick. As movement of the selected group of electrodes occurs, current redistribution amongst the various electrode contacts takes place. The redistribution of stimulus amplitudes utilizes re-normalization of amplitudes so that the perceptual level remains fairly constant. This prevents the resulting paresthesia from falling below the perceptual threshold or above the comfort threshold.

2. 发明申请

US20160136430A1 CLOSED-LOOP FEEDBACK FOR STEERING STIMULATION ENERGY WITHIN TISSUE 审中-公开
标题翻译：闭合反馈在组织中转向刺激能量
公开(公告)号：US20160136430A1
公开(公告)日：2016-05-19
申请号：US15006185
申请日：2016-01-26
申请人： Boston Scientific Neuromodulation Corporation
发明人： Michael A. Moffitt , David K. L. Peterson , Paul M. Meadows
IPC分类号： A61N1/36 , A61N1/372 , A61N1/05
CPC分类号： A61N1/36139 , A61N1/0531 , A61N1/0534 , A61N1/0553 , A61N1/36067 , A61N1/36082 , A61N1/36185 , A61N1/36189 , A61N1/37235
摘要： Methods, systems, and external programmers provide therapy to a patient having a dysfunction. In one aspect, electrical energy is conveyed between electrodes to create a stimulation region in tissue adjacent the electrodes. Physiological information from the patient is acquired and analyzed, and a locus of the stimulation region is electronically displaced relative to the tissue based on the analysis of the acquired physiological information. In another aspect, electrical energy is delivered to tissue of the patient in accordance with one or more stimulation parameters. A cognitive brain signals is sensed and analyzed, and the stimulation parameter(s) are modified based on the analysis of the cognitive brain signal.
摘要翻译：方法，系统和外部程序员为具有功能障碍的患者提供治疗。在一个方面，电能在电极之间传送以在邻近电极的组织中产生刺激区域。获取和分析来自患者的生理信息，并且基于所获取的生理信息的分析，刺激区域的位置相对于组织电子移位。在另一方面，根据一个或多个刺激参数将电能输送到患者的组织。感知和分析认知脑信号，并且基于对认知脑信号的分析来修改刺激参数。

3. 发明授权

US08965529B2 Devices with cannula and electrode lead for brain stimulation and methods of use and manufacture 有权
标题翻译：具有插管和电极引线用于脑刺激的装置以及使用和制造方法
公开(公告)号：US08965529B2
公开(公告)日：2015-02-24
申请号：US14274615
申请日：2014-05-09
申请人： Boston Scientific Neuromodulation Corporation
发明人： Michael Adam Moffitt , Paul M. Meadows
IPC分类号： A61N1/00 , A61B17/34 , A61N1/05 , A61N1/36
CPC分类号： A61B17/3468 , A61N1/0529 , A61N1/0534 , A61N1/36017 , A61N1/36025 , A61N1/36082
摘要： A device for brain stimulation includes a cannula configured and arranged for insertion into a brain of a patient; at least one cannula electrode disposed on the cannula; and an electrode lead for insertion into the cannula, the electrode lead comprising at least one stimulating electrode.
摘要翻译：用于脑刺激的装置包括配置并布置成用于插入患者脑中的插管; 设置在套管上的至少一个套管电极; 以及用于插入插管的电极引线，所述电极引线包括至少一个刺激电极。

4. 发明授权

US08676345B2 Electrodes for stimulation leads and methods of manufacture and use 失效
标题翻译：刺激电极用电极及制造及使用方法
公开(公告)号：US08676345B2
公开(公告)日：2014-03-18
申请号：US14063676
申请日：2013-10-25
申请人： Boston Scientific Neuromodulation Corporation
发明人： Paul M. Meadows , Randall Lee Brase
IPC分类号： A61N1/00
CPC分类号： A61N1/05 , A61N1/0551 , A61N1/3605 , A61N1/37223 , H01R43/00
摘要： An electrode has a unitary ring with an exterior surface, interior surface, and at least two edges. The electrode also includes a seat formed in at least the exterior surface of the unitary ring. The seat is configured and arranged for attachment of a terminal end of a lead wire, disposed in the seat, to the electrode. A lead includes a lead body; a plurality of electrodes disposed at the distal end of the lead body; and a plurality of lead wires. Each electrode includes a unitary ring and a seat in the unitary ring. The unitary ring has an exterior surface and an interior surface and defines a hollow center region. The seat is formed as a depression of a portion of the unitary ring. Each of the lead wires extends along the lead body and is attached to a corresponding electrode at the seat of the corresponding electrode.
摘要翻译：电极具有整体环，其具有外表面，内表面和至少两个边缘。电极还包括形成在整体环的至少外表面中的座。座椅被构造和布置成用于将设置在座椅中的引线的终端连接到电极。铅包括铅体; 设置在所述引线体的前端的多个电极; 和多根引线。每个电极包括单一环和单一环中的座。整体环具有外表面和内表面并且限定中空中心区域。座椅形成为整体环的一部分的凹陷。每个引线沿着引线主体延伸并且附接到相应电极的座处的对应的电极。

5. 发明申请

US20130304171A1 DEVICES AND METHODS FOR BRAIN STIMULATION 有权
标题翻译：脑刺激的装置和方法
公开(公告)号：US20130304171A1
公开(公告)日：2013-11-14
申请号：US13943175
申请日：2013-07-16
申请人： BOSTON SCIENTIFIC NEUROMODULATION CORPORATION
发明人： Paul M. Meadows
IPC分类号： A61N1/05
CPC分类号： A61N1/3606 , A61N1/0529 , A61N1/0534 , A61N1/36003 , A61N1/36017 , A61N1/36021 , A61N1/36025 , A61N1/36071 , A61N1/36082
摘要： A device for brain stimulation that includes a lead having a longitudinal surface; at least one stimulation electrode disposed along the longitudinal surface of the lead; and at least one recording electrode, separate from the at least one stimulation electrode, disposed along the longitudinal surface of the lead.
摘要翻译：一种用于脑刺激的装置，其包括具有纵向表面的引线; 沿着铅的纵向表面布置的至少一个刺激电极; 以及沿着所述引线的纵向表面设置的至少一个与所述至少一个刺激电极分离的记录电极。

6. 发明申请

US20140249598A1 DEVICES AND METHODS FOR BRAIN STIMULATION 审中-公开
标题翻译：脑刺激的装置和方法
公开(公告)号：US20140249598A1
公开(公告)日：2014-09-04
申请号：US14274606
申请日：2014-05-09
申请人： Boston Scientific Neuromodulation Corporation
发明人： Paul M. Meadows
IPC分类号： A61N1/05 , A61N1/36
CPC分类号： A61N1/3606 , A61N1/0529 , A61N1/0534 , A61N1/36003 , A61N1/36017 , A61N1/36021 , A61N1/36025 , A61N1/36071 , A61N1/36082
摘要： A device for brain stimulation that includes n lead having a longitudinal surface; at least one stimulation electrode disposed along the longitudinal surface of the lead; and at least one recording electrode, separate from the at least one stimulation electrode, disposed along she longitudinal surface of the lead.
摘要翻译：一种用于脑刺激的装置，其包括具有纵向表面的n个引线; 沿着铅的纵向表面布置的至少一个刺激电极; 以及沿着所述引线的纵向表面设置的至少一个与所述至少一个刺激电极分离的记录电极。

7. 发明申请

US20140018894A1 DEVICES WITH CANNULA AND ELECTRODE LEAD FOR BRAIN STIMULATION AND METHODS OF USE AND MANUFACTURE 有权
标题翻译：具有腋窝和电极引导用于脑刺激的装置及其使用和制造方法
公开(公告)号：US20140018894A1
公开(公告)日：2014-01-16
申请号：US14023022
申请日：2013-09-10
申请人： Boston Scientific Neuromodulation Corporation
发明人： Michael Adam Moffitt , Paul M. Meadows
IPC分类号： A61N1/05
CPC分类号： A61B17/3468 , A61N1/0529 , A61N1/0534 , A61N1/36017 , A61N1/36025 , A61N1/36082
摘要： A device for brain stimulation includes a cannula configured and arranged for insertion into a brain of a patient; at least one cannula electrode disposed on the cannula; and an electrode lead for insertion into the cannula, the electrode lead comprising at least one stimulating electrode.
摘要翻译：用于脑刺激的装置包括配置并布置成用于插入患者脑中的插管; 设置在套管上的至少一个套管电极; 以及用于插入插管的电极引线，所述电极引线包括至少一个刺激电极。

8. 发明授权

US09050473B2 System for normalizing amplitude programming of a tissue stimulator 有权
标题翻译：用于使组织刺激器的幅度规划正常化的系统
公开(公告)号：US09050473B2
公开(公告)日：2015-06-09
申请号：US14325924
申请日：2014-07-08
申请人： BOSTON SCIENTIFIC NEUROMODULATION CORPORATION
发明人： Carla Mann Woods , David K. L. Peterson , Paul M. Meadows , Gerald E. Loeb
IPC分类号： A61N1/00 , A61N1/36 , A61N1/05 , A61N1/372
CPC分类号： A61N1/36185 , A61N1/0551 , A61N1/0553 , A61N1/36071 , A61N1/37235 , A61N1/37247
摘要： An implantable pulse generator includes a current steering capability that allows a clinician or patient to quickly determine a desired electrode stimulation pattern, including which electrodes of a group of electrodes within an electrode array should receive a stimulation current, including the amplitude, width and pulse repetition rate of such current. Movement of the selected group of electrodes is facilitated through the use of remotely generated directional signals, generated by a pointing device, such as a joystick. As movement of the selected group of electrodes occurs, current redistribution amongst the various electrode contacts takes place. The redistribution of stimulus amplitudes utilizes re-normalization of amplitudes so that the perceptual level remains fairly constant. This prevents the resulting paresthesia from falling below the perceptual threshold or above the comfort threshold.
摘要翻译：可植入脉冲发生器包括电流转向能力，其允许临床医生或患者快速确定期望的电极刺激图案，包括电极阵列内的一组电极中的哪些电极应接收刺激电流，包括振幅，宽度和脉冲重复这样的比率。所选择的电极组的移动通过使用由诸如操纵杆的指示装置产生的远程产生的方向信号来促进。随着所选择的电极组的移动发生，各种电极接触件之间的电流再分配发生。刺激幅度的再分配利用振幅的再归一化，使得感知水平保持相当恒定。这可以防止由此产生的感觉异常降低到感知阈值以下或高于舒适阈值。

9. 发明申请

US20150039048A1 IMPLANTABLE PULSE GENERATOR HAVING CURRENT STEERING MEANS 审中-公开
公开(公告)号：US20150039048A1
公开(公告)日：2015-02-05
申请号：US14489131
申请日：2014-09-17
申请人： BOSTON SCIENTIFIC NEUROMODULATION CORPORATION
发明人： Carla Mann Woods , David K.L. Peterson , Paul M. Meadows , Gerald E. Loeb
IPC分类号： A61N1/36
CPC分类号： A61N1/36185 , A61N1/0551 , A61N1/0553 , A61N1/36071 , A61N1/37235 , A61N1/37247
摘要： An implantable pulse generator includes a current steering capability that allows a clinician or patient to quickly determine a desired electrode stimulation pattern, including which electrodes of a group of electrodes within an electrode array should receive a stimulation current, including the amplitude, width and pulse repetition rate of such current. Movement of the selected group of electrodes is facilitated through the use of remotely generated directional signals, generated by a pointing device, such as a joystick. As movement of the selected group of electrodes occurs, current redistribution amongst the various electrode contacts takes place. The redistribution of stimulus amplitudes utilizes re-normalization of amplitudes so that the perceptual level remains fairly constant. This prevents the resulting paresthesia from falling below the perceptual threshold or above the comfort threshold.

10. 发明授权

US08938308B2 Devices and methods for brain stimulation 有权
标题翻译：脑刺激的装置和方法
公开(公告)号：US08938308B2
公开(公告)日：2015-01-20
申请号：US14274606
申请日：2014-05-09
申请人： Boston Scientific Neuromodulation Corporation
发明人： Paul M. Meadows
IPC分类号： A61N1/05 , A61N1/36
CPC分类号： A61N1/3606 , A61N1/0529 , A61N1/0534 , A61N1/36003 , A61N1/36017 , A61N1/36021 , A61N1/36025 , A61N1/36071 , A61N1/36082
摘要： A device for brain stimulation that includes n lead having a longitudinal surface; at least one stimulation electrode disposed along the longitudinal surface of the lead; and at least one recording electrode, separate from the at least one stimulation electrode, disposed along she longitudinal surface of the lead.
摘要翻译：一种用于脑刺激的装置，其包括具有纵向表面的n个引线; 沿着铅的纵向表面布置的至少一个刺激电极; 以及沿着所述引线的纵向表面设置的至少一个与所述至少一个刺激电极分离的记录电极。

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