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1. 发明申请

US20070060948A1 Portable hand-operable device for applying pneumatic pressure pulses to an ear canal 有权
标题翻译：用于向耳道施加气动压力脉冲的便携式手动操作装置
公开(公告)号：US20070060948A1
公开(公告)日：2007-03-15
申请号：US10557167
申请日：2004-05-19
申请人： Burkhard Franz , Richard Stephens , Christopher Peters
发明人： Burkhard Franz , Richard Stephens , Christopher Peters
IPC分类号： A61B17/00
CPC分类号： A61F11/00 , A61M39/22 , F16K15/021 , F16K15/18
摘要： A hand-held device (10) for creating a pressure change in a person's ear canal. It has an interior space forming an air chamber (50), a plunger (58) and a valve means (52) frictionally engaged with said plunger (58), a tube (14) with an earpiece (48), and a finger-actuated diaphragm (60) in an external wall of the air chamber (50). The diaphragm (60) moves the plunger (58) from a resting position, and in a first direction. A spring (56) returns the diaphragm (60) to its undepressed position. Initial movement of the plunger (58) in said first direction from said resting position displaces the valve (52) from a first position to a second position at which the valve means (52) is stopped from further movement in said first direction. Further movement of the plunger (58) in said first direction causes the plunger (58) to slide relative to the valve (52). The device (10) is intended for treatment of Mënière's disease and ear pain from other causes.
摘要翻译：一种用于在人的耳道中产生压力变化的手持装置（10）。它具有形成空气室（50），柱塞（58）和与所述柱塞（58）摩擦接合的阀装置（52）的内部空间，具有耳塞（48）的手指管（14）在空气室（50）的外壁中的致动隔膜（60）。隔膜（60）使活塞（58）从静止位置和第一方向移动。弹簧（56）将隔膜（60）返回到其未受压位置。柱塞（58）沿着所述第一方向从所述静止位置的初始移动将阀（52）从第一位置移位到第二位置，在该位置处，阀装置（52）停止在所述第一方向上的进一步移动。柱塞（58）沿所述第一方向的进一步运动使得柱塞（58）相对于阀（52）滑动。设备（10）旨在用于治疗梅内尔氏病和其他原因引起的耳痛。

2. 发明授权

US5821055A Chlamydia major outer membrane protein 失效
公开(公告)号：US5821055A
公开(公告)日：1998-10-13
申请号：US468451
申请日：1995-06-06
申请人： Nina Agabian , Richard Stephens , Cho-Chou Kuo , Guy Mullenbach
发明人： Nina Agabian , Richard Stephens , Cho-Chou Kuo , Guy Mullenbach
IPC分类号： C07K14/295 , C12Q1/68 , G01N33/569 , C07H21/02 , C07H21/04 , C12P19/34
CPC分类号： C07K14/295 , C12Q1/689 , G01N33/56927 , C07K2319/00 , C07K2319/035 , C07K2319/40 , C07K2319/61 , G01N2333/295 , G01N2469/20
摘要： Methods and compositions are provided for the production of a polypeptide which is immunologically cross-reactive with a naturally-occurring major outer membrane protein (MOMP) of Chlamydia trachomatis. A DNA construct including a replication system recognized by E. coli, and an MOMP gene under the transcriptional control of a .beta.-galactosidase promoter and terminator is provided. Recombinant phage .lambda.gt11/L2/33 was deposited at the American Type Culture Collection, 12301 Parklawn Drive, Rockville, Md. 20852, on Jan. 10, 1985 and granted accession no. 40157. L2 B9-F DNA was deposited at the American Type Culture Collection on Dec. 31, 1985, and granted accession No. 40217.

3. 发明授权

US5770714A Chlamydia major outer membrane protein 失效
标题翻译：衣原体主要外膜蛋白
公开(公告)号：US5770714A
公开(公告)日：1998-06-23
申请号：US466814
申请日：1995-06-06
申请人： Nina Agabian , Richard Stephens , Cho-Chou Kuo , Guy Mullenbach
发明人： Nina Agabian , Richard Stephens , Cho-Chou Kuo , Guy Mullenbach
IPC分类号： C07K14/295 , C12Q1/68 , G01N33/569 , C07H21/02 , C07H21/04 , C07K5/00 , C07K13/00
CPC分类号： C07K14/295 , C12Q1/689 , G01N33/56927 , C07K2319/00 , C07K2319/035 , C07K2319/40 , C07K2319/61 , G01N2333/295 , G01N2469/20
摘要： Methods and compositions are provided for the production of a polypeptide which is immunologically cross-reactive with a naturally-occurring major outer membrane protein (MOMP) of Chlamydia trachomatis. A DNA construct including a replication system recognized by E. coli, and an MOMP gene under the transcriptional control of a .beta.-galactosidase promoter and terminator is provided. Recombinant phage .lambda.gt11/L2/33 was deposited at the American Type Culture Collection, 12301 Parklawn Drive, Rockville, Md. 20852, on Jan. 10, 1985 and granted accession no. 40157. L2 B9-F DNA was deposited at the American Type Culture Collection on Dec. 31, 1985, and granted accession No. 40217.
摘要翻译：提供了用于产生与沙眼衣原体的天然存在的主要外膜蛋白（MOMP）具有免疫交叉反应性的多肽的方法和组合物。提供了包括大肠杆菌识别的复制系统的DNA构建体和在β-半乳糖苷酶启动子和终止子的转录控制下的MOMP基因。重组噬菌体λgt11/ L2 / 33于1985年1月10日保藏于美国典型培养物保藏中心（American Type Culture Collection），12301 Parklawn Drive，Rockville，Md。20852。 L15B9-F DNA于1985年12月31日在美国典型培养物保藏中心保藏，授予第40217号。

4. 发明授权

US09422099B2 Insulated container with work surface 有权
标题翻译：绝缘容器带工作面
公开(公告)号：US09422099B2
公开(公告)日：2016-08-23
申请号：US14312108
申请日：2014-06-23
申请人： Elizabeth Mitchell , Mike Baatz , William Kearns , Christopher Edwards , Melvin Mogil , Richard Stephens
发明人： Elizabeth Mitchell , Mike Baatz , William Kearns , Christopher Edwards , Melvin Mogil , Richard Stephens
IPC分类号： B65D81/38 , A45C11/20 , A45F3/02 , A45C7/00 , A45C9/00 , B65D25/14 , B65D25/28 , B65D45/00
CPC分类号： B65D81/3888 , A45C7/0077 , A45C9/00 , A45C11/20 , A45C13/005 , A45C13/103 , A45C13/30 , A45F3/02 , B65D25/14 , B65D25/28 , B65D43/16 , B65D45/00 , B65D81/38
摘要： A soft sided insulated container assembly includes a first portion having an insulated, soft sided external wall structure, and a second portion that defined a lid co-operable with the first portion. The lid includes an auxiliary access opening and closure member that are smaller than the main opening, and that can be operated one-handed. A rigid work surface is provided, typically immediately adjacent to the secondary closure member, the work surface providing a place for holding or mixing a drink or for preparing a snack. In some embodiments the work surface may be movable relative to the container, whether slidable in a co-planar or parallel planar manner in translation, or folding as in a foldable shelf. The entire container assembly may be foldable or collapsible to a storage condition, and the rigid member, whether fixed or movable, does not impede that folding or collapsing.
摘要翻译：软侧绝缘容器组件包括具有绝缘的，柔软的侧壁外壁结构的第一部分和限定与第一部分可协作的盖的第二部分。盖子包括一个小于主开口的辅助通道开口和闭合件，可以单手操作。提供刚性工作表面，通常紧邻次级封闭构件，工作表面提供用于保持或混合饮料或用于制备小吃的地方。在一些实施例中，工作表面可以相对于容器是可移动的，无论是如何以平面或平行的平面方式在平移中可滑动，或者如可折叠货架那样折叠。整个容器组件可以是可折叠的或可折叠的存储状态，并且刚性构件（无论是固定的或可移动的）不会妨碍折叠或折叠。

5. 发明申请

US20070195487A1 Energy storage device 有权
公开(公告)号：US20070195487A1
公开(公告)日：2007-08-23
申请号：US11790374
申请日：2007-04-25
申请人： David James , Stephen Wilson , Alina Sloan , Richard Stephens
发明人： David James , Stephen Wilson , Alina Sloan , Richard Stephens
IPC分类号： H01G9/00
CPC分类号： H01G9/155 , H01G2/06 , H01G9/016 , H01G9/10 , H01G11/52 , H01G11/74 , H01G11/82 , H01M2/0207 , H01M2/30 , H01M6/10 , H01M6/42 , H01M10/04 , H01M10/0436 , Y02E60/13 , Y10T29/41 , Y10T29/417
摘要： A surface mount energy storage device in the form of a supercapacitor (1) includes a generally rectangular folded prismatic housing (2) and two energy storage elements (not shown) that are sealingly contained within the housing (2) and which are connected in series. A mount, in the form of an integrally formed tinned metal frame (3), extends about and captively retains housing (2) in the folded configuration shown. Two terminals, in the form of elongate contacts (4, 5) extend from the energy storage elements and terminate outside housing (2) for allowing external electrical connection to the elements.

6. 发明申请

US20060233826A1 Porin B (PorB) as a therapeutic target for prevention and treatment of infection by Chlamydia 有权
公开(公告)号：US20060233826A1
公开(公告)日：2006-10-19
申请号：US11414278
申请日：2006-04-27
申请人： Richard Stephens , Diane Kawa
发明人： Richard Stephens , Diane Kawa
IPC分类号： A61K39/02 , C07H21/04 , C12P21/04 , C07K16/12 , C07K14/295
CPC分类号： A61K39/118 , A61K39/00 , A61K2039/53 , C07K14/295 , G01N33/56927 , Y10S530/806 , Y10S530/825
摘要： The present invention features peptides of a PorB polypeptide, which PorB peptides are useful in production of antibodies that bind the full-length PorB polypeptide and as a therapeutic agent. In specific embodiments the invention features a composition comprising one or more PorB peptides (other than a full-length PorB polypeptide), which peptides contain at least one epitope that can elicit Chlamydia-neutralizing antibodies. The invention also features methods for induction of a protective immune response against infection by Chlamydia and Chlamydiophila.

7. 发明授权

US6030799A Immunoassays for detecting chlamydial antigens or antibodies thereto using recombinant or synthetic major outer membrane protein polypeptides as substitute antigens 失效
标题翻译：使用重组或合成的主要外膜蛋白多肽作为替代抗原来检测衣原体抗原或其抗体的免疫测定
公开(公告)号：US6030799A
公开(公告)日：2000-02-29
申请号：US466152
申请日：1995-06-06
申请人： Nina Agabian , Richard Stephens , Cho-Chou Kuo , Guy Mullenbach
发明人： Nina Agabian , Richard Stephens , Cho-Chou Kuo , Guy Mullenbach
IPC分类号： C07K14/295 , C12Q1/68 , G01N33/569 , G01N33/571 , A61K38/00 , C12N15/00 , C12P21/04
CPC分类号： C07K14/295 , C12Q1/689 , G01N33/56927 , C07K2319/00 , C07K2319/035 , C07K2319/40 , C07K2319/61 , G01N2333/295 , G01N2469/20
摘要： Methods and compositions are provided for the production of a polypeptide which is immunologically cross-reactive with a naturally-occurring major outer membrane protein (MOMP) of Chlamydia trachomatis. A DNA construct including a replication system recognized by E. coli, and an MOMP gene under the transcriptional control of a .beta.-glactosidase promoter and terminator is provided. Recombinant phage .lambda.gtll/L2/33 was deposited at the American Type Culture Collection, 12301 Parklawn Drive, Rockville, Md. 20852, on Jan. 10, 1985 and granted accession no. 40157. L2 B9-F DNA was deposited at the American Type Culture Collection on Dec. 31, 1985, and granted accession No. 40217.
摘要翻译：提供了用于产生与沙眼衣原体的天然存在的主要外膜蛋白（MOMP）具有免疫交叉反应性的多肽的方法和组合物。提供了包含由大肠杆菌识别的复制系统的DNA构建体和在β-谷氨酸酶启动子和终止子的转录控制下的MOMP基因。 1985年1月10日，重组噬菌体λgtll/ L2 / 33保藏于美国典型培养物保藏中心（American Type Culture Collection），12301 Parklawn Drive，Rockville，Md。20852，并授予登录号。 L15B9-F DNA于1985年12月31日在美国典型培养物保藏中心保藏，授予第40217号。

8. 发明授权

US08777045B2 Insulated container with work surface 有权
标题翻译：绝缘容器带工作面
公开(公告)号：US08777045B2
公开(公告)日：2014-07-15
申请号：US13532182
申请日：2012-06-25
申请人： Elizabeth Mitchell , Mike Baatz , William Kearns , Christopher Edwards , Melvin Mogil , Richard Stephens
发明人： Elizabeth Mitchell , Mike Baatz , William Kearns , Christopher Edwards , Melvin Mogil , Richard Stephens
IPC分类号： B65D81/38 , B65D25/14 , B65D25/28 , B65D45/00
CPC分类号： B65D81/3888 , A45C7/0077 , A45C9/00 , A45C11/20 , A45C13/005 , A45C13/103 , A45C13/30 , A45F3/02 , B65D25/14 , B65D25/28 , B65D43/16 , B65D45/00 , B65D81/38
摘要： A soft sided insulated container assembly includes a first portion having an insulated, soft sided external wall structure, and a second portion that defined a lid co-operable with the first portion. The lid includes an auxiliary access opening and closure member that are smaller than the main opening, and that can be operated one-handed. A rigid work surface is provided, typically immediately adjacent to the secondary closure member, the work surface providing a place for holding or mixing a drink or for preparing a snack. In some embodiments the work surface may be movable relative to the container, whether slidable in a co-planar or parallel planar manner in translation, or folding as in a foldable shelf. The entire container assembly may be foldable or collapsible to a storage condition, and the rigid member, whether fixed or movable, does not impede that folding or collapsing.
摘要翻译：软侧绝缘容器组件包括具有绝缘的，柔软的侧壁外壁结构的第一部分和限定与第一部分可协作的盖的第二部分。盖子包括一个小于主开口的辅助通道开口和闭合件，可以单手操作。提供刚性工作表面，通常紧邻次级封闭构件，工作表面提供用于保持或混合饮料或用于制备小吃的地方。在一些实施例中，工作表面可以相对于容器是可移动的，无论是如何以平面或平行的平面方式在平移中可滑动，或者如可折叠货架那样折叠。整个容器组件可以是可折叠的或可折叠的存储状态，并且刚性构件（无论是固定的或可移动的）不会妨碍折叠或折叠。

9. 发明申请

US20130341338A1 INSULATED CONTAINER WITH WORK SURFACE 有权
公开(公告)号：US20130341338A1
公开(公告)日：2013-12-26
申请号：US13532182
申请日：2012-06-25
申请人： Elizabeth Mitchell , Mike Baatz , William Kearns , Christopher Edwards , Melvin Mogil , Richard Stephens
发明人： Elizabeth Mitchell , Mike Baatz , William Kearns , Christopher Edwards , Melvin Mogil , Richard Stephens
IPC分类号： B65D81/38
CPC分类号： B65D81/3888 , A45C7/0077 , A45C9/00 , A45C11/20 , A45C13/005 , A45C13/103 , A45C13/30 , A45F3/02 , B65D25/14 , B65D25/28 , B65D43/16 , B65D45/00 , B65D81/38
摘要： A soft sided insulated container assembly includes a first portion having an insulated, soft sided external wall structure, and a second portion that defined a lid co-operable with the first portion. The lid includes an auxiliary access opening and closure member that are smaller than the main opening, and that can be operated one-handed. A rigid work surface is provided, typically immediately adjacent to the secondary closure member, the work surface providing a place for holding or mixing a drink or for preparing a snack. In some embodiments the work surface may be movable relative to the container, whether slidable in a co-planar or parallel planar manner in translation, or folding as in a foldable shelf. The entire container assembly may be foldable or collapsible to a storage condition, and the rigid member, whether fixed or movable, does not impede that folding or collapsing.

10. 发明授权

US07180866B1 Rerouting in connection-oriented communication networks and communication systems 有权
标题翻译：在面向连接的通信网络和通信系统中重新路由
公开(公告)号：US07180866B1
公开(公告)日：2007-02-20
申请号：US10192498
申请日：2002-07-11
申请人： Denis Chartre , Jack Zgierski , Darren Newell , Richard Stephens
发明人： Denis Chartre , Jack Zgierski , Darren Newell , Richard Stephens
IPC分类号： G01R31/08
CPC分类号： H04L45/10 , H04L43/0811 , H04L45/04 , H04L45/22 , H04L45/28 , H04Q2213/13141 , H04Q2213/13145 , H04Q2213/13204 , H04Q2213/1329 , H04Q2213/13292 , H04Q2213/13348 , H04Q2213/13389
摘要： A Private Network-Network Interface (PNNI) network including interconnected nodes is defined as a single rerouting domain (“global domain”) and the global domain is further defined by multiple divided domains (“local domains”). Each of the local domains is defined to include multiple nodes that are included in the network. Connection recovery and path optimization in the global domain (the entire PNNI network) are performed in accordance with a global rerouting protocol. The global rerouting protocol is a modification of the standard Domain-Based Rerouting (DBR) protocol, by adding information elements of domain identifier, rerouting for the global domain. The DBR protocol does not support the connection recovery from a link failure between local domains (“inter-domains”) and the global path optimization. The global rerouting method is capable of connection recovery and path optimization outside of any rerouting local domains. The global rerouting provides double fault recovery within the rerouting domain (“intra-domain”) as covered by the DBR and outside of the domains (“inter-domain”) or when the initial fault recovery within the domain has failed. Also, the global rerouting method provides maximum path optimization across all domains and within the rerouting local domain.
摘要翻译：包括互连节点的私有网络 - 网络接口（PNNI）网络被定义为单个重路由域（“全局域”），并且全局域由多个分割域（“本地域”）进一步定义。每个本地域被定义为包括在网络中的多个节点。根据全局重路由协议执行全局域（整个PNNI网络）中的连接恢复和路径优化。全局重路由协议是通过添加域标识符的信息元素，重新路由到全局域，来修改标准的基于域的重路由（DBR）协议。 DBR协议不支持本地域（“域间”）与全局路径优化之间的链路故障的连接恢复。全局重路由方法能够在任何重新路由的本地域之外进行连接恢复和路径优化。全局重新路由在由DBR和域外（“域间”）覆盖的重路由域（“域内”）内或域内的初始故障恢复失败时提供双重故障恢复。此外，全局重路由方法提供跨所有域和重路由本地域中的最大路径优化。

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