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1. 发明授权

US09510764B2 Methods for detecting atrial tachyarrhythmia in implantable devices without dedicated atrial sensing 有权
标题翻译：在没有专门心房感应的植入式装置中检测心房快速性心律失常的方法
公开(公告)号：US09510764B2
公开(公告)日：2016-12-06
申请号：US12754932
申请日：2010-04-06
申请人： Dan Li , David L. Perschbacher , Yanting Dong , Julie Stephenson
发明人： Dan Li , David L. Perschbacher , Yanting Dong , Julie Stephenson
IPC分类号： A61B5/0464 , A61B5/00 , A61B5/04 , A61N1/362 , A61N1/365
CPC分类号： A61B5/0464 , A61B5/0006 , A61B5/0031 , A61B5/04012 , A61B5/686 , A61N1/3624 , A61N1/36592
摘要： An apparatus comprises an implantable cardiac signal sensing circuit configured to provide a sensed depolarization signal from a ventricle and a processor. The processor includes a signal analyzer module and a tachyarrhythmia discrimination module. The signal analyzer module is configured to determine a measure of stability of ventricular (V-V) depolarization intervals using the depolarization signal, and determine a rate of change of the measure of stability. The tachyarrhythmia discrimination module is configured to detect an episode of tachyarrhythmia using the depolarization signal, determine whether the detected tachyarrhythmia is indicative of atrial tachyarrhythmia using the determined rate of change, and provide the determination to a user or process.
摘要翻译：一种装置包括可植入心脏信号感测电路，其被配置为提供来自心室和处理器的感测去极化信号。处理器包括信号分析器模块和快速心律失常辨别模块。信号分析器模块被配置为使用去极化信号来确定心室（V-V）去极化间隔的稳定性的量度，并且确定稳定性测量的变化率。快速心律失常辨别模块被配置为使用去极化信号来检测快速性心律失常发作，使用确定的变化率确定检测到的快速性心律失常是指示心房快速性心律失常，并且向用户或过程提供确定。

2. 发明申请

US20100274149A1 METHODS FOR DETECTING ATRIAL TACHYARRHYTHMIA IN IMPLANTABLE DEVICES WITHOUT DEDICATED ATRIAL SENSING 有权
标题翻译：用于在没有专用ATRIAL感觉的可植入器件中检测ATRY TACHYARRHYTHMIA的方法
公开(公告)号：US20100274149A1
公开(公告)日：2010-10-28
申请号：US12754932
申请日：2010-04-06
申请人： Dan Li , David L. Perschbacher , Yanting Dong , Julie Stephenson
发明人： Dan Li , David L. Perschbacher , Yanting Dong , Julie Stephenson
IPC分类号： A61B5/0464
CPC分类号： A61B5/0464 , A61B5/0006 , A61B5/0031 , A61B5/04012 , A61B5/686 , A61N1/3624 , A61N1/36592
摘要： An apparatus comprises an implantable cardiac signal sensing circuit configured to provide a sensed depolarization signal from a ventricle and a processor. The processor includes a signal analyzer module and a tachyarrhythmia discrimination module. The signal analyzer module is configured to determine a measure of stability of ventricular (V-V) depolarization intervals using the depolarization signal, and determine a rate of change of the measure of stability. The tachyarrhythmia discrimination module is configured to detect an episode of tachyarrhythmia using the depolarization signal, determine whether the detected tachyarrhythmia is indicative of atrial tachyarrhythmia using the determined rate of change, and provide the determination to a user or process.
摘要翻译：一种装置包括可植入心脏信号感测电路，其被配置为提供来自心室和处理器的感测去极化信号。处理器包括信号分析器模块和快速心律失常辨别模块。信号分析器模块被配置为使用去极化信号来确定心室（V-V）去极化间隔的稳定性的量度，并且确定稳定性测量的变化率。快速心律失常辨别模块被配置为使用去极化信号来检测快速性心律失常发作，使用确定的变化率确定检测到的快速性心律失常是指示心房快速性心律失常，并且向用户或过程提供确定。

3. 发明申请

US20110130666A1 ENHANCED REPORTING OF PATHOLOGICAL EPISODES 审中-公开
标题翻译：增强病理学报告
公开(公告)号：US20110130666A1
公开(公告)日：2011-06-02
申请号：US12916843
申请日：2010-11-01
申请人： Yanting Dong , David L. Perschbacher , Dan Li , Deepa Mahajan , F. Roosevelt Gilliam
发明人： Yanting Dong , David L. Perschbacher , Dan Li , Deepa Mahajan , F. Roosevelt Gilliam
IPC分类号： A61B5/0205 , A61B5/00 , A61B5/0402 , A61B5/0464
CPC分类号： A61B5/04525 , A61B5/02028 , A61B5/0215 , A61B5/02438 , A61B5/0464 , A61B5/0816 , A61B5/14503 , A61B7/00 , A61N1/36521 , A61N1/36557 , A61N1/36564 , A61N1/36578
摘要： An apparatus comprises a sensor circuit configured to produce a time-varying physiologic sensor signal of a subject and a pathology detection circuit communicatively coupled to the sensor. The pathology detection circuit is configured to detect a first pathological episode using the sensed physiologic sensor signal, deem that the first pathological episode has ended, detect at least one second pathological episode using the sensed physiologic sensor signal, and indicate the first and second pathological episodes as one pathological episode if the first and second episode are detected within a specified time interval.
摘要翻译：一种装置包括被配置为产生受试者的时变生理传感器信号的传感器电路和通信地耦合到传感器的病理检测电路。病理检测电路被配置为使用感测到的生理传感器信号来检测第一病理发作，认为第一病理发作已经结束，使用感测到的生理传感器信号检测至少一个第二病理发作，并且指示第一和第二病理发作作为一个病理发作，如果在指定的时间间隔内检测到第一和第二集。

4. 发明申请

US20100305642A1 ADAPTIVE EVENT STORAGE IN IMPLANTABLE DEVICE 有权
标题翻译：可插入设备中的自适应事件存储
公开(公告)号：US20100305642A1
公开(公告)日：2010-12-02
申请号：US12781459
申请日：2010-05-17
申请人： Yanting Dong , David L. Perschbacher , Jeffrey E. Stahmann , Dan Li , Deepa Mahajan
发明人： Yanting Dong , David L. Perschbacher , Jeffrey E. Stahmann , Dan Li , Deepa Mahajan
IPC分类号： A61N1/00
CPC分类号： A61N1/37252 , A61B5/02 , A61B5/04 , A61B5/0452 , A61B5/6846 , A61N1/025 , A61N1/3621 , A61N1/3702 , A61N1/372 , A61N1/3925
摘要： Monitoring physiological parameter using an implantable physiological monitor in order to detect a condition predictive of a possible future pathological episode and collecting additional physiological data associated with the condition predictive of a possible future pathological episode. Monitoring another physiological parameter in order to detect a condition indicative of the beginning of a present pathological episode and collecting additional pathological data in response to the condition. Determining that the condition predictive of a future episode and the condition indicative of a present episode are associated and, in response thereto, storing all the collected physiological data.
摘要翻译：使用植入式生理监测器监测生理参数，以便检测预测可能的未来病理发作的状况并收集与预测可能的未来病理发作相关的条件相关的附加生理数据。监测另一个生理参数，以便检测指示本病理发作开始的病症，并根据病情收集额外的病理资料。确定预测未来事件的状况和指示当前情节的状况是相关联的，并且响应于此，存储所有收集的生理数据。

5. 发明授权

US08649860B2 Adaptive event storage in implantable device 有权
标题翻译：可植入装置中的自适应事件存储
公开(公告)号：US08649860B2
公开(公告)日：2014-02-11
申请号：US12781459
申请日：2010-05-17
申请人： Yanting Dong , David L. Perschbacher , Jeffrey E. Stahmann , Dan Li , Deepa Mahajan
发明人： Yanting Dong , David L. Perschbacher , Jeffrey E. Stahmann , Dan Li , Deepa Mahajan
IPC分类号： A61N1/39
CPC分类号： A61N1/37252 , A61B5/02 , A61B5/04 , A61B5/0452 , A61B5/6846 , A61N1/025 , A61N1/3621 , A61N1/3702 , A61N1/372 , A61N1/3925
摘要： Monitoring physiological parameter using an implantable physiological monitor in order to detect a condition predictive of a possible future pathological episode and collecting additional physiological data associated with the condition predictive of a possible future pathological episode. Monitoring another physiological parameter in order to detect a condition indicative of the beginning of a present pathological episode and collecting additional pathological data in response to the condition. Determining that the condition predictive of a future episode and the condition indicative of a present episode are associated and, in response thereto, storing all the collected physiological data.
摘要翻译：使用植入式生理监测器监测生理参数，以便检测预测可能的未来病理发作的状况并收集与预测可能的未来病理发作相关的条件相关的附加生理数据。监测另一个生理参数，以便检测指示本病理发作开始的病症，并根据病情收集额外的病理资料。确定预测未来事件的状况和指示当前情节的状况是相关联的，并且响应于此，存储所有收集的生理数据。

6. 发明申请

US20100280841A1 Adjudication of Arrhythmia Episode Data Systems and Methods 审中-公开
标题翻译：心律失常发作数据系统与方法的判断
公开(公告)号：US20100280841A1
公开(公告)日：2010-11-04
申请号：US12771103
申请日：2010-04-30
申请人： Yanting Dong , David L. Perschbacher , Dan Li , Deepa Mahajan , Shijie Zhang , Arjun Sharma , Abhilash Patangay
发明人： Yanting Dong , David L. Perschbacher , Dan Li , Deepa Mahajan , Shijie Zhang , Arjun Sharma , Abhilash Patangay
IPC分类号： G06Q50/00 , A61N1/36
CPC分类号： A61B5/04012 , A61B5/042 , A61B5/046 , A61B5/0464 , A61B5/7264 , A61B5/7267 , A61B5/7475 , A61N1/37247 , G06F19/324 , G06Q50/22 , G16H15/00 , G16H40/63
摘要： A system and method for automatically adjudicating arrhythmia episode information is described, and includes an episode database having episode data regarding a plurality of different arrhythmia episodes and an adjudication processor configured to output characterization data characterizing the input episode data. The characterization data includes an arrhythmia classification. The system further includes an episode processor configured to process the characterization data and episode data, provide at least one report on the characterization data related to a plurality of the different arrhythmia episodes, and provide at least one programming recommendation or at least one alert.
摘要翻译：描述了用于自动判断心律失常发作信息的系统和方法，并且包括具有关于多个不同心律失常发作的剧集数据的剧集数据库，以及被配置为输出表征输入剧集数据的表征数据的裁定处理器。表征数据包括心律失常分类。该系统还包括配置用于处理表征数据和发作数据的剧集处理器，提供关于与多个不同心律失常发作有关的表征数据的至少一个报告，并提供至少一个节目推荐或至少一个警报。

7. 发明授权

US08639324B2 Respiratory parameters for arrhythmia detection and therapy 有权
标题翻译：心律失常检测和治疗的呼吸参数
公开(公告)号：US08639324B2
公开(公告)日：2014-01-28
申请号：US13353515
申请日：2012-01-19
申请人： Efdal Elferri , Randall L. McPherson , Donald L. Hopper , Gary T. Seim , James O. Gilkerson , Dan Li , David L. Perschbacher
发明人： Efdal Elferri , Randall L. McPherson , Donald L. Hopper , Gary T. Seim , James O. Gilkerson , Dan Li , David L. Perschbacher
IPC分类号： A61B5/0205 , A61N1/365 , A61N1/39
CPC分类号： A61N1/36585 , A61B5/0464 , A61B5/0538 , A61B5/0809 , A61B5/091 , A61B5/686 , A61N1/3962
摘要： An implantable or ambulatory medical device can include a cardiac signal sensing circuit configured to provide a sensed cardiac depolarization signal of a heart of a subject, a respiration sensing circuit configured to provide a signal representative of respiration of the subject, and a control circuit communicatively coupled to the cardiac signal sensing circuit and the respiration circuit. The control circuit includes a tachyarrhythmia detection circuit configured to determine heart rate using the depolarization signal, determine a respiration parameter of the subject using the respiration signal, calculate a ratio using the determined heart rate and the determined respiration parameter, generate an indication of tachyarrhythmia when the calculated ratio satisfies a specified detection ratio threshold value, and provide the indication of tachyarrhythmia to a user or process.
摘要翻译：植入式或动态医疗装置可以包括心脏信号感测电路，该心脏信号感测电路被配置为提供受检者的心脏的感测的心脏去极化信号，被配置为提供代表对象呼吸的信号的呼吸感测电路，以及通信耦合的控制电路到心脏信号感测电路和呼吸电路。控制电路包括快速性心律失常检测电路，其被配置为使用去极化信号来确定心率，使用呼吸信号确定受试者的呼吸参数，使用所确定的心率和确定的呼吸参数来计算比率，产生快速性心律失常的指示，所计算的比率满足规定的检测率阈值，并向用户或过程提供快速性心律失常的指示。

8. 发明授权

US09101773B2 Cross-channel noise detector in implantable medical devices 有权
标题翻译：可植入医疗器械中的跨通道噪声检测器
公开(公告)号：US09101773B2
公开(公告)日：2015-08-11
申请号：US12693512
申请日：2010-01-26
申请人： Dan Li , David L. Perschbacher
发明人： Dan Li , David L. Perschbacher
IPC分类号： A61N1/365 , A61N1/37 , A61N1/39
CPC分类号： A61N1/3704 , A61N1/3718 , A61N1/3925
摘要： An apparatus comprises a primary cardiac signal sensing circuit to sense a first cardiac signal, a secondary cardiac signal sensing to sense a second cardiac signal, and an arrhythmia detection circuit. The primary sensing circuit includes at least first and second implantable electrodes, and the secondary sensing circuit includes a third implantable electrode to deliver high-energy shock therapy. The arrhythmia detection circuit detects tachyarrhythmia using the primary sensing circuit, determines correspondence between events sensed with the primary sensing circuit and events sensed with the secondary sensing circuit, and deems whether a detected rhythm is indicative of noise or is indicative of an arrhythmia according to the determined correspondence.
摘要翻译：一种装置包括用于感测第一心脏信号的主要心脏信号感测电路，感测第二心脏信号的次要心脏信号感测和心律失常检测电路。主感测电路至少包括第一和第二可植入电极，并且次级感测电路包括用于输送高能量休克疗法的第三可植入电极。心律失常检测电路使用主感测电路检测快速性心律失常，确定用主感测电路感测的事件与由次级感测电路感测的事件之间的对应关系，并且考虑检测到的节奏是指示噪声还是指示心律失常根据确定的信件。

9. 发明申请

US20120197323A1 RESPIRATORY PARAMETERS FOR ARRHYTHMIA DETECTION AND THERAPY 有权
标题翻译： ARRHYTHMIA检测和治疗的呼吸参数
公开(公告)号：US20120197323A1
公开(公告)日：2012-08-02
申请号：US13353515
申请日：2012-01-19
申请人： Efdal Elferri , Randall L. McPherson , Donald L. Hopper , Gary T. Seim , James O. Gilkerson , Dan Li , David L. Perschbacher
发明人： Efdal Elferri , Randall L. McPherson , Donald L. Hopper , Gary T. Seim , James O. Gilkerson , Dan Li , David L. Perschbacher
IPC分类号： A61N1/39 , A61N1/365 , A61B5/0205
CPC分类号： A61N1/36585 , A61B5/0464 , A61B5/0538 , A61B5/0809 , A61B5/091 , A61B5/686 , A61N1/3962
摘要： An implantable or ambulatory medical device can include a cardiac signal sensing circuit configured to provide a sensed cardiac depolarization signal of a heart of a subject, a respiration sensing circuit configured to provide a signal representative of respiration of the subject, and a control circuit communicatively coupled to the cardiac signal sensing circuit and the respiration circuit. The control circuit includes a tachyarrhythmia detection circuit configured to determine heart rate using the depolarization signal, determine a respiration parameter of the subject using the respiration signal, calculate a ratio using the determined heart rate and the determined respiration parameter, generate an indication of tachyarrhythmia when the calculated ratio satisfies a specified detection ratio threshold value, and provide the indication of tachyarrhythmia to a user or process.
摘要翻译：植入式或动态医疗装置可以包括心脏信号感测电路，该心脏信号感测电路被配置为提供受检者的心脏的感测的心脏去极化信号，被配置为提供代表对象呼吸的信号的呼吸感测电路，以及通信耦合的控制电路到心脏信号感测电路和呼吸电路。控制电路包括快速性心律失常检测电路，其被配置为使用去极化信号来确定心率，使用呼吸信号确定受试者的呼吸参数，使用所确定的心率和确定的呼吸参数来计算比率，产生快速性心律失常的指示，所计算的比率满足规定的检测率阈值，并向用户或过程提供快速性心律失常的指示。

10. 发明申请

US20100204745A1 CROSS-CHANNEL NOISE DETECTOR IN IMPLANTABLE MEDICAL DEVICES 有权
标题翻译：可移植医疗设备中的通道噪声检测器
公开(公告)号：US20100204745A1
公开(公告)日：2010-08-12
申请号：US12693512
申请日：2010-01-26
申请人： Dan Li , David L. Perschbacher
发明人： Dan Li , David L. Perschbacher
IPC分类号： A61N1/362
CPC分类号： A61N1/3704 , A61N1/3718 , A61N1/3925
摘要： An apparatus comprises a primary cardiac signal sensing circuit to sense a first cardiac signal, a secondary cardiac signal sensing to sense a second cardiac signal, and an arrhythmia detection circuit. The primary sensing circuit includes at least first and second implantable electrodes, and the secondary sensing circuit includes a third implantable electrode to deliver high-energy shock therapy. The arrhythmia detection circuit detects tachyarrhythmia using the primary sensing circuit, determines correspondence between events sensed with the primary sensing circuit and events sensed with the secondary sensing circuit, and deems whether a detected rhythm is indicative of noise or is indicative of an arrhythmia according to the determined correspondence.
摘要翻译：一种装置包括用于感测第一心脏信号的主要心脏信号感测电路，感测第二心脏信号的次要心脏信号感测和心律失常检测电路。主感测电路至少包括第一和第二可植入电极，并且次级感测电路包括用于输送高能量休克疗法的第三可植入电极。心律失常检测电路使用主感测电路检测快速性心律失常，确定用主感测电路感测的事件与由次级感测电路感测的事件之间的对应关系，并且考虑检测到的节奏是指示噪声还是指示心律失常根据确定的信件。

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