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1. 发明授权

US08046062B2 Post-shock management of implantable cardiac device features 失效
标题翻译：可植入心脏装置功能的后冲击管理
公开(公告)号：US08046062B2
公开(公告)日：2011-10-25
申请号：US12545643
申请日：2009-08-21
申请人： David J. Yonce , Scott Meyer , David J. Ternes
发明人： David J. Yonce , Scott Meyer , David J. Ternes
IPC分类号： A61N1/00
CPC分类号： A61N1/3962 , A61B5/04525 , A61N1/3712 , A61N1/3943
摘要： Systems and methods of managing features or functions of an implantable cardiac device involve forming a baseline evoked response template prior to delivery of defibrillation therapy to a patient's heart, and acquiring a post-shock evoked response signal subsequent to defibrillation therapy delivery. The baseline evoked response template is compared to the post-shock evoked response signal. A determination is made whether to enable, disable or adjust a cardiac device feature based on the comparison. The cardiac device feature may be a therapy feature, a monitoring feature, or a diagnostic feature.
摘要翻译：管理可植入心脏装置的特征或功能的系统和方法包括在将除颤疗法递送到患者心脏之前形成基线诱发反应模板，以及在除颤治疗递送之后获得后休克诱发反应信号。将基线诱发反应模板与震后诱发反应信号进行比较。基于比较确定是否启用，禁用或调整心脏设备特征。心脏装置特征可以是治疗特征，监测特征或诊断特征。

2. 发明申请

US20090312810A1 Post-Shock Management of Implantable Cardiac Device Features 失效
标题翻译：可植入心脏装置功能的冲击后管理
公开(公告)号：US20090312810A1
公开(公告)日：2009-12-17
申请号：US12545643
申请日：2009-08-21
申请人： David J. Yonce , Scott A. Meyer , David J. Ternes
发明人： David J. Yonce , Scott A. Meyer , David J. Ternes
IPC分类号： A61N1/39 , A61N1/37
CPC分类号： A61N1/3962 , A61B5/04525 , A61N1/3712 , A61N1/3943
摘要： Systems and methods of managing features or functions of an implantable cardiac device involve forming a baseline evoked response template prior to delivery of defibrillation therapy to a patient's heart, and acquiring a post-shock evoked response signal subsequent to defibrillation therapy delivery. The baseline evoked response template is compared to the post-shock evoked response signal. A determination is made whether to enable, disable or adjust a cardiac device feature based on the comparison. The cardiac device feature may be a therapy feature, a monitoring feature, or a diagnostic feature.
摘要翻译：管理可植入心脏装置的特征或功能的系统和方法包括在将除颤疗法递送到患者心脏之前形成基线诱发反应模板，以及在除颤治疗递送之后获得后休克诱发反应信号。将基线诱发反应模板与震后诱发反应信号进行比较。基于比较确定是否启用，禁用或调整心脏设备特征。心脏装置特征可以是治疗特征，监测特征或诊断特征。

3. 发明授权

US07593771B2 Post-shock management of implantable cardiac device features 有权
标题翻译：可植入心脏装置功能的后冲击管理
公开(公告)号：US07593771B2
公开(公告)日：2009-09-22
申请号：US11157244
申请日：2005-06-21
申请人： David J. Yonce , Scott A. Meyer , David J. Ternes
发明人： David J. Yonce , Scott A. Meyer , David J. Ternes
IPC分类号： A61N1/00
CPC分类号： A61N1/3962 , A61B5/04525 , A61N1/3712 , A61N1/3943
摘要： Systems and methods of managing features or functions of an implantable cardiac device involve forming a baseline evoked response template prior to delivery of defibrillation therapy to a patient's heart, and acquiring a post-shock evoked response signal subsequent to defibrillation therapy delivery. The baseline evoked response template is compared to the post-shock evoked response signal. A determination is made whether to enable, disable or adjust a cardiac device feature based on the comparison. The cardiac device feature may be a therapy feature, a monitoring feature, or a diagnostic feature.
摘要翻译：管理可植入心脏装置的特征或功能的系统和方法包括在将除颤疗法递送到患者心脏之前形成基线诱发反应模板，以及在除颤治疗递送之后获得后休克诱发反应信号。将基线诱发反应模板与震后诱发反应信号进行比较。基于比较确定是否启用，禁用或调整心脏设备特征。心脏装置特征可以是治疗特征，监测特征或诊断特征。

4. 发明授权

US07583998B2 Multi-chamber cardiac capture detection using cross chamber sensing 有权
标题翻译：使用交叉腔感测的多室心脏捕获检测
公开(公告)号：US07583998B2
公开(公告)日：2009-09-01
申请号：US11157426
申请日：2005-06-21
申请人： Scott A. Meyer , David J. Yonce , David J. Ternes
发明人： Scott A. Meyer , David J. Yonce , David J. Ternes
IPC分类号： A61N1/37
CPC分类号： A61N1/368 , A61N1/3684 , A61N1/3712
摘要： Methods and systems involve multi-chamber cardiac capture detection utilizing sensing during a cross-chamber refractory period. First and second pacing pulses are delivered to first and second heart chamber. Capture or non-capture of the second heart chamber is determined. Sensing in the first heart chamber is performed to sense for cross-chamber propagation initiated by the second pacing pulse. Capture of the first chamber is detected if capture of the second heart chamber is detected and if the cross-chamber propagation is not detected.
摘要翻译：方法和系统涉及在跨室不应期期间利用感测的多室心脏捕获检测。第一和第二起搏脉冲被输送到第一和第二心室。确定第二心室的捕获或非捕获。执行在第一心室中的感测以感测由第二起搏脉冲发起的交叉腔传播。如果检测到第二心室的捕获并且未检测到横隔室传播，则检测到第一腔室的捕获。

5. 发明授权

US09138590B2 Implantable medical device sensing and selecting wireless ECG and intracardiac electrogram 有权
标题翻译：植入式医疗器械感测和选择无线心电图和心内电图
公开(公告)号：US09138590B2
公开(公告)日：2015-09-22
申请号：US13535104
申请日：2012-06-27
申请人： Yi Zhang , Aaron McCabe , David J. Yonce , Julie Thompson
发明人： Yi Zhang , Aaron McCabe , David J. Yonce , Julie Thompson
IPC分类号： A61N1/372 , A61N1/39 , A61N1/362 , A61N1/37 , A61N1/375 , A61N1/08
CPC分类号： A61N1/3956 , A61B5/0422 , A61B5/0452 , A61B5/686 , A61N1/3622 , A61N1/3706 , A61N1/3712 , A61N1/3756 , A61N1/3925 , A61N2001/083
摘要： A CRM system enhances intracardiac electrogram-based arrhythmia detection using a wireless electrocardiogram (ECG), which is a signal sensed with implantable electrodes and approximating a surface ECG. In one embodiment, an intracardiac electrogram allows for detection of an arrhythmia, and the wireless ECG allows for classification of the detected arrhythmia by locating its origin. In another embodiment, the wireless ECG is sensed as a substitute signal for the intracardiac electrogram when the sensing of the intracardiac electrogram becomes unreliable. In another embodiment, a cardiac signal needed for a particular purpose is selected from one or more intracardiac electrograms and one or more wireless ECGs based on a desirable signal quality. In another embodiment, intracardiac electrogram-based arrhythmia detection and wireless ECG-based arrhythmia detection confirm with each other before indicating a detection of arrhythmia of a certain type.
摘要翻译： CRM系统使用无线心电图（ECG）来增强基于心脏电图的心律失常检测，无线心电图（ECG）是用可植入电极感测并近似表面ECG的信号。在一个实施例中，心内电描记图允许检测心律失常，并且无线ECG允许通过定位其起点来分类检测到的心律失常。在另一个实施例中，当心脏电图的感测变得不可靠时，无线ECG被感测为心内电描记图的替代信号。在另一个实施例中，基于期望的信号质量，从一个或多个心内电描记图和一个或多个无线ECG选择特定目的所需的心脏信号。在另一个实施例中，基于心脏电图的心律失常检测和基于无线ECG的心律失常检测在指示某种类型的心律失常的检测之前相互确认。

6. 发明授权

US07277754B2 Method and system for removing pacing artifacts from subcutaneous electrocardiograms 有权
标题翻译：用于从皮下心电图中去除起搏假象的方法和系统
公开(公告)号：US07277754B2
公开(公告)日：2007-10-02
申请号：US10746855
申请日：2003-12-24
申请人： Aaron McCabe , David J. Yonce
发明人： Aaron McCabe , David J. Yonce
IPC分类号： A61N1/36
CPC分类号： A61N1/3704 , Y10S128/923
摘要： An implantable cardiac rhythm management device is configured to remove pacing artifacts from recorded electrograms by a subtraction method. A template waveform representing a recorded pace without accompanying cardiac electrical activity is generated. Such a pacing pulse template is then aligned with the instant at which a pace is delivered and subtracted from the recorded electrogram in order to remove the pacing artifact.
摘要翻译：植入式心律管理装置被配置为通过减法方法从记录的电描记图中去除起搏伪影。产生表示没有伴随心脏电活动的记录速度的模板波形。然后将这样的起搏脉冲模板与速度被传送的时刻对准，并从所记录的电描记图中减去，以便去除起搏假象。

7. 发明授权

US07113823B2 Morphology-based optimization of cardiac resynchronization therapy 有权
公开(公告)号：US07113823B2
公开(公告)日：2006-09-26
申请号：US10723255
申请日：2003-11-26
申请人： David J. Yonce , David Ternes
发明人： David J. Yonce , David Ternes
IPC分类号： A61N1/18
CPC分类号： A61N1/3712 , A61B5/04525 , A61B5/7264 , A61N1/3627 , A61N1/3682 , A61N1/3684
摘要： A method and apparatus for delivering cardiac resynchronization therapy (CRT) in which an evoked response electrogram is recorded during one or more cardiac cycles and used to aid in the selection of resynchronization pacing parameters and/or to monitor the effectiveness of resynchronization therapy. The morphology of an evoked response electrogram may be recorded and analyzed to determine if and when intrinsic activation of one ventricle is occurring in order to optimally adjust the programmed atrio-ventricular (AV) delay interval for ventricular resynchronization pacing of a patient with intact AV node conduction.

8. 发明授权

US06741886B2 ECG system with minute ventilation detector 有权
标题翻译：心电图系统与分钟通气检测器
公开(公告)号：US06741886B2
公开(公告)日：2004-05-25
申请号：US10037773
申请日：2001-10-25
申请人： David J. Yonce
发明人： David J. Yonce
IPC分类号： A61B504
CPC分类号： A61B5/0424 , A61B5/0031 , A61B5/0535 , A61B5/7203 , A61N1/36521
摘要： The ability of an ecg apparatus to detect and display pacing pulses from the surface electrodes on a patient in whom a minute ventilation-based rate adaptive pacemaker is implanted is improved by providing the ecg apparatus with a minute ventilation detection circuit capable of indicating the time of occurrence and repetition rate of bursts of AC carrier signals which the implanted pacemaker generates in deriving a minute ventilation related control signal for the implanted pacemaker. In addition to improving the ability of the ecg system to detect and record paced events, the incorporation of the MV detection into the ecg system accommodates leads-off detection by coordinating the generation of the leads-off drive signal with the MV carrier signal generated by the implanted pacer.
摘要翻译：通过向ecg装置提供能够指示时间的微小通气检测电路，从而改善ecg装置检测和显示起搏脉冲从患者体内的微小通气率适应性心脏起搏器植入的患者的起搏脉冲的能力植入起搏器产生的AC载波信号突发的发生和重复率导出用于植入的起搏器的每分钟通气相关的控制信号。除了提高ecg系统检测和记录节奏事件的能力之外，将MV检测结合到心电图系统中还可以通过协调引导关闭驱动信号的产生与由MV载波信号产生的MV载波信号来适应通断检测植入起搏器。

9. 发明授权

US06438406B2 Voltage sensing system with input impedance balancing for electrocardiogram (ECG) sensing applications 有权
公开(公告)号：US06438406B2
公开(公告)日：2002-08-20
申请号：US09765722
申请日：2001-01-18
申请人： David J. Yonce
发明人： David J. Yonce
IPC分类号： A61B50428
CPC分类号： H03F3/45475 , A61B5/0428 , H03F3/45932 , H03F2200/261 , Y10S128/901 , Y10S128/902
摘要： A voltage sensing system includes input impedance balancing for electrocardiogram (ECG) sensing or other applications, providing immunity to common-mode noise signals while capable of use with two electrodes. Signals are received at first and second electrodes having associated impedances. An impedance circuit includes a feedback controller that adjusts an effective impedance associated with the second electrode based on a difference signal, a common mode signal, a phase-shifted (e.g., quadrature common mode) signal, and an impedance associated with the first electrode. As a result, signals associated with each electrode undergo a similar degree of gain/attenuation and/or phase-shift. This reduces common mode noise and enhances the signal-to-noise characteristics of a desired ECG or other output signal, without requiring the use of more than two electrodes.

10. 发明授权

US06407931B1 DC to DC converter 失效
标题翻译：直流到直流转换器
公开(公告)号：US06407931B1
公开(公告)日：2002-06-18
申请号：US09614467
申请日：2000-07-11
申请人： David J. Yonce , Scott T. Mazar , Scott R. Vanderlinde
发明人： David J. Yonce , Scott T. Mazar , Scott R. Vanderlinde
IPC分类号： H05K900
CPC分类号： H05K1/0256 , H05K1/0262 , H05K3/306 , H05K2201/1003 , H05K2201/10568 , H05K2201/2036
摘要： A DC to DC converter having a flange attached to the housing. The flange configured to electrically isolate, insulate and shield the DC to DC converter from an underlying circuit board. The flange may be further configured to meet creepage distances and air clearances required by various regulatory and certification agencies.
摘要翻译：一种具有附接到壳体的凸缘的DC至DC转换器。该凸缘被配置为将DC-DC转换器与底层电路板电隔离，绝缘和屏蔽。该凸缘可进一步构造成满足各种监管和认证机构所要求的爬电距离和空气间隙。

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