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1. 发明申请

US20100268310A1 IMPLANTABLE MEDICAL ELECTRICAL STIMULATION LEAD, SUCH AS PNE LEAD, AND METHOD OF USE 审中-公开
标题翻译：可植入医用电刺激引线，如PNE引线和使用方法
公开(公告)号：US20100268310A1
公开(公告)日：2010-10-21
申请号：US12827435
申请日：2010-06-30
申请人： Eric H. Bonde , Eric M. Stetz , Carole A. Tronnes
发明人： Eric H. Bonde , Eric M. Stetz , Carole A. Tronnes
IPC分类号： A61N1/05
CPC分类号： A61N1/0558
摘要： An implantable medical electrode lead for stimulation of bodily tissue. The lead is adapted for use with a needle lumen diameter of not greater than 0.05 inch, and includes a lead body and a tine assembly. The lead body has a distal section forming at least one exposed electrode surface. The tine assembly includes a plurality of tines each having a base end coupled to an exterior of the lead body immediately adjacent the exposed electrode surface and a free end that is movable relative to the lead body to inhibit axial migration of the lead body upon implantation into a patient. In one embodiment, the lead body is a PNE lead and provides two electrode surfaces for bipolar operation.
摘要翻译：用于刺激身体组织的可植入医用电极引线。引线适用于针腔直径不大于0.05英寸，并且包括引线体和齿组件。引线体具有形成至少一个暴露的电极表面的远端部分。齿组件包括多个尖齿，每个尖头具有紧邻暴露的电极表面的引线体的外部的基端，以及相对于引线本体可移动的自由端，以阻止引线体在植入时的轴向迁移病人。在一个实施例中，引线体是PNE引线，并提供用于双极性操作的两个电极表面。

2. 发明授权

US08892214B2 Multi-electrode peripheral nerve evaluation lead and related system and method of use 有权
标题翻译：多电极周围神经评估线及相关系统及使用方法
公开(公告)号：US08892214B2
公开(公告)日：2014-11-18
申请号：US11413432
申请日：2006-04-28
申请人： Eric H. Bonde , Eric M. Stetz , Carole A. Tronnes , James T. Henry
发明人： Eric H. Bonde , Eric M. Stetz , Carole A. Tronnes , James T. Henry
IPC分类号： A61N1/06 , A61N1/05
CPC分类号： A61B5/04001 , A61B5/6848 , A61N1/0551 , A61N1/0558
摘要： An implantable electrical lead for applying stimulation energy to bodily tissue, such as a patient's nervous system, from an external power source. The lead is defined by a distal section, an intermediate section and a proximal section, and includes a lead body, a plurality of insulated wires, and a plurality of connector elements. The lead body includes a plurality of electrodes and an anchoring device. The insulated wires are electrically coupled to the electrodes, respectively. A wire intermediate segment extends proximal the lead body and is characterized as having a non-coiled configuration, terminating at a respective connector element for coupling to an external power source. The wire intermediate segments are extendible through a patient's skin and are sealable relative to the skin. The lead is adapted for providing temporary electrical stimulation to a sacral nerve in a bipolar mode, with the anchoring device inhibiting electrode migration.
摘要翻译：用于从外部电源向身体组织（例如患者神经系统）施加刺激能量的可植入电线。引线由远端部分，中间部分和近端部分限定，并且包括引线主体，多个绝缘电线和多个连接器元件。引线体包括多个电极和锚定装置。绝缘电线分别电耦合到电极。导线中间段在引线体的近侧延伸，并且其特征在于具有非卷绕构型，终止于相应的连接器元件，用于耦合到外部电源。线中间段可通过患者的皮肤延伸并且相对于皮肤可密封。引线适于在双极模式下向骶神经提供临时电刺激，锚定装置抑制电极迁移。

3. 发明申请

US20110202097A1 SYSTEM AND METHOD FOR ELECTRICALLY PROBING AND PROVIDING MEDICAL ELECTRICAL STIMULATION 审中-公开
标题翻译：用于电气探测和提供医疗电刺激的系统和方法
公开(公告)号：US20110202097A1
公开(公告)日：2011-08-18
申请号：US13095488
申请日：2011-04-27
申请人： Eric H. Bonde , Eric M. Stetz , Carole A. Tronnes
发明人： Eric H. Bonde , Eric M. Stetz , Carole A. Tronnes
IPC分类号： A61N1/36
CPC分类号： A61N1/0551
摘要： A system for providing medical electrical stimulation including a lead assembly and a cannula. The lead assembly includes a lead body and a needle tip. The lead body has a distal section and a proximal section. The needle tip is formed of an electrically conductive material and is connected to the distal section of the lead body. The lead body is slidably disposed within a cannula lumen, with a distal end of the cannula being selectively connected to an abutment surface of the needle tip such that the needle tip extends distal the cannula to define a needle probe. With this construction, the lead assembly can be delivered to a desired implantation site via manipulation of the cannula and/or energization of the needle tip, and the cannula can be removed from the lead body without requiring movement of the needle tip.
摘要翻译：一种用于提供医疗电刺激的系统，包括引线组件和套管。引线组件包括引线体和针尖。引线体具有远侧部分和近端部分。针尖由导电材料形成并且连接到引线主体的远端部分。引导体可滑动地设置在套管腔内，套管的远端选择性地连接到针尖的邻接表面，使得针尖延伸到套管的远端以限定针头探针。利用这种结构，引导组件可以通过插管的操作和/或针尖的通电而被输送到期望的植入位置，并且可以不用移动针尖从导线主体移除套管。

4. 发明授权

US07949408B2 System and method for electrically probing and providing medical electrical stimulation 有权
标题翻译：电探测和提供医疗电刺激的系统和方法
公开(公告)号：US07949408B2
公开(公告)日：2011-05-24
申请号：US11413310
申请日：2006-04-28
申请人： Eric H. Bonde , Eric M. Stetz , Carole A. Tronnes
发明人： Eric H. Bonde , Eric M. Stetz , Carole A. Tronnes
IPC分类号： A61N1/05
CPC分类号： A61N1/0551
摘要： A system for providing medical electrical stimulation including a lead assembly and a cannula. The lead assembly includes a lead body and a needle tip. The lead body has a distal section and a proximal section. The needle tip is formed of an electrically conductive material and is connected to the distal section of the lead body. The lead body is slidably disposed within a cannula lumen, with a distal end of the cannula being selectively connected to an abutment surface of the needle tip such that the needle tip extends distal the cannula to define a needle probe. With this construction, the lead assembly can be delivered to a desired implantation site via manipulation of the cannula and/or energization of the needle tip, and the cannula can be removed from the lead body without requiring movement of the needle tip.
摘要翻译：一种用于提供医疗电刺激的系统，包括引线组件和套管。引线组件包括引线体和针尖。引线体具有远侧部分和近端部分。针尖由导电材料形成并且连接到引线主体的远端部分。引导体可滑动地设置在套管腔内，套管的远端选择性地连接到针尖的邻接表面，使得针尖延伸到套管的远端以限定针头探针。利用这种结构，引导组件可以通过插管的操作和/或针尖的通电而被输送到期望的植入位置，并且可以不用移动针尖从导线主体移除套管。

5. 发明授权

US07881783B2 Implantable medical electrical stimulation lead, such as a PNE lead, and method of use 有权
标题翻译：植入式医疗电刺激引线，如PNE引线，以及使用方法
公开(公告)号：US07881783B2
公开(公告)日：2011-02-01
申请号：US11413301
申请日：2006-04-28
申请人： Eric H. Bonde , Eric M. Stetz , Carole A. Tronnes
发明人： Eric H. Bonde , Eric M. Stetz , Carole A. Tronnes
IPC分类号： A61N1/05
CPC分类号： A61N1/0558
摘要： An implantable medical electrode lead for stimulation of bodily tissue. The lead is adapted for use with a needle lumen diameter of not greater than 0.05 inch, and includes a lead body and a tine assembly. The lead body has a distal section forming at least one exposed electrode surface. The tine assembly includes a plurality of tines each having a base end coupled to an exterior of the lead body immediately adjacent the exposed electrode surface and a free end that is movable relative to the lead body to inhibit axial migration of the lead body upon implantation into a patient. In one embodiment, the lead body is a PNE lead and provides two electrode surfaces for bipolar operation.
摘要翻译：用于刺激身体组织的可植入医用电极引线。引线适用于针腔直径不大于0.05英寸，并且包括引线体和齿组件。引线体具有形成至少一个暴露的电极表面的远端部分。齿组件包括多个尖齿，每个尖头具有紧邻暴露的电极表面的引线体的外部的基端，以及相对于引线本体可移动的自由端，以阻止引线体在植入时的轴向迁移病人。在一个实施例中，引线体是PNE引线，并提供用于双极性操作的两个电极表面。

6. 发明授权

US08204575B2 Locating guide 失效
标题翻译：定位指南
公开(公告)号：US08204575B2
公开(公告)日：2012-06-19
申请号：US11835296
申请日：2007-08-07
申请人： Eric M. Stetz , Eric H. Bonde , Yelena G. Tropsha , Thomas Chun
发明人： Eric M. Stetz , Eric H. Bonde , Yelena G. Tropsha , Thomas Chun
IPC分类号： A61B5/05
CPC分类号： A61B90/39 , A61B90/11 , A61B2090/376 , A61B2090/3916 , A61B2090/3983 , A61N1/0551 , A61N1/08
摘要： A locating guide for locating a target tissue site within a patient includes a body, a first substantially radiopaque reference marker on the body, and a second substantially radiopaque reference marker extending from a major surface of the body. The reference markers provide reference points that extend in at least two dimensions, and may be useful for registering a medical image of tissue with an actual location on or within the patient in order to more accurately and precisely locate a target tissue site within the patient. In some embodiments, the second reference marker is oriented at a predetermined angle relative to the major surface of the body, and provides a guide that a clinician may reference in order to orient a medical element introducer when introducing the introducer into the patient to access a particular target tissue site.
摘要翻译：用于定位患者内的目标组织部位的定位引导件包括主体，身体上的第一基本上不透射线的参考标记以及从主体的主表面延伸的第二基本不透射线的参考标记。参考标记提供在至少两个维度上延伸的参考点，并且可用于将具有实际位置的组织的医学图像登记在患者身上或内部，以便更精确地和精确地定位患者内的目标组织部位。在一些实施例中，第二参考标记物相对于主体的主表面以预定角度定向，并且提供临床医生可引用的引导件，以便在将导引器引入患者时进行定位以导向医疗元件导入器特定目标组织部位。

7. 发明授权

US6144866A Multiple sensor assembly for medical electric lead 有权
标题翻译：多用于医疗电源的传感器组件
公开(公告)号：US6144866A
公开(公告)日：2000-11-07
申请号：US182970
申请日：1998-10-30
申请人： Keith A. Miesel , Jonathan P. Roberts , John C. Olson , Roger LaFond , Brenda Chatelle , Eric M. Stetz
发明人： Keith A. Miesel , Jonathan P. Roberts , John C. Olson , Roger LaFond , Brenda Chatelle , Eric M. Stetz
IPC分类号： A61B5/00 , A61B5/0215 , A61B5/03 , A61N1/05 , A61N1/365
CPC分类号： A61B5/6864 , A61B5/02154 , A61B5/031 , A61B5/14539 , A61B5/1459 , A61N1/056 , A61N1/36585
摘要： An implantable sensor assembly for use with an implantable medical device are disclosed. The sensor assembly preferably includes two or more physiologic sensors coupled to the medical device via a pair of lead conductors, or alternatively an oxygen sensor having certain features. The oxygen sensor permits more accurate and reliable measurement of oxygen saturation in blood masses flowing within the human body.
摘要翻译：公开了一种用于可植入医疗装置的植入式传感器组件。传感器组件优选地包括经由一对引线导体或具有某些特征的氧传感器耦合到医疗装置的两个或更多个生理传感器。氧气传感器可以更精确和可靠地测量人体内血液中的血氧饱和度。

8. 发明申请

US20080120836A1 MODULAR ASSEMBLY OF MEDICAL ELECTRICAL LEADS 有权
标题翻译：医用电源模块化组件
公开(公告)号：US20080120836A1
公开(公告)日：2008-05-29
申请号：US12025403
申请日：2008-02-04
申请人： BRUCE R. MEHDIZADEH , Thomas C. Bischoff , Scott J. Robinson , Eric M. Stetz , James W. Millin
发明人： BRUCE R. MEHDIZADEH , Thomas C. Bischoff , Scott J. Robinson , Eric M. Stetz , James W. Millin
IPC分类号： H01R43/00 , H01R43/20
CPC分类号： H01R24/58 , H01R2105/00 , H01R2201/12 , Y10S439/909 , Y10T29/49169 , Y10T29/49176 , Y10T29/49208 , Y10T29/4922 , Y10T29/49222
摘要： A modular terminal assembly, which may be a connector assembly, for a medical electrical lead includes at least one contact conductor extending therefrom that may or may not be coupled to a lead body conductor. A lead body assembly, for the medical electrical lead that includes the lead body conductor may be selected from a group of different lead body assemblies.
摘要翻译：可以是用于医疗电引线的连接器组件的模块化端子组件包括从其延伸的至少一个接触导体，其可以或可以不联接到引线体导体。用于包括引线体导体的医用电引线的引线体组件可以选自一组不同的引线体组件。

9. 发明授权

US6125291A Light barrier for medical electrical lead oxygen sensor 有权
标题翻译：医用电导线氧传感器的光栅
公开(公告)号：US6125291A
公开(公告)日：2000-09-26
申请号：US182764
申请日：1998-10-30
申请人： Keith A. Miesel , Eric M. Stetz
发明人： Keith A. Miesel , Eric M. Stetz
IPC分类号： A61B5/00 , A61B5/0215 , A61B5/03 , A61N1/365 , A61N5/08
CPC分类号： A61B5/6864 , A61B5/0215 , A61B5/031 , A61B5/14539 , A61B5/1459 , A61B5/0031 , A61N1/36557
摘要： An implantable sensor assembly for use with an implantable medical device are disclosed. The sensor assembly preferably includes two or more physiologic sensors coupled to the medical device via a pair of lead conductors, or alternatively an oxygen sensor having certain features. The oxygen sensor permits more accurate and reliable measurement of oxygen saturation in blood masses flowing within the human body.
摘要翻译：公开了一种用于可植入医疗装置的植入式传感器组件。传感器组件优选地包括经由一对引线导体或具有某些特征的氧传感器耦合到医疗装置的两个或更多个生理传感器。氧气传感器可以更精确和可靠地测量人体内血液中的血氧饱和度。

10. 发明授权

US09027241B2 Method of assembling a medical electrical lead 有权
标题翻译：组装医用电线的方法
公开(公告)号：US09027241B2
公开(公告)日：2015-05-12
申请号：US12025403
申请日：2008-02-04
申请人： Bruce R. Mehdizadeh , Thomas C. Bischoff , Scott J. Robinson , Eric M. Stetz , James W. Millin
发明人： Bruce R. Mehdizadeh , Thomas C. Bischoff , Scott J. Robinson , Eric M. Stetz , James W. Millin
IPC分类号： H01R43/00 , H05K13/00 , H01R24/58 , H01R105/00
CPC分类号： H01R24/58 , H01R2105/00 , H01R2201/12 , Y10S439/909 , Y10T29/49169 , Y10T29/49176 , Y10T29/49208 , Y10T29/4922 , Y10T29/49222
摘要： A method of assembling a medical electrical lead. The method comprises providing a modular connector assembly including three contacts coupled to three contact conductors, selecting a lead body assembly from a group of different lead body assemblies which includes a first lead body assembly having only two conductors for and a second lead body assembly having three conductors; and coupling each of the conductors of the selected lead body assembly with a corresponding contact conductor of the modular connector assembly.
摘要翻译：一种组装医用电线的方法。该方法包括提供包括耦合到三个接触导体的三个触点的模块化连接器组件，从一组不同的引线主体组件中选择引线主体组件，所述引线主体组件包括仅具有两个导体的第一引线主体组件和具有三个导体以及将所选择的引线本体组件的每个导体与模块化连接器组件的对应的接触导体耦合。

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