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1. 发明授权

US08805546B2 Cochlear electrode with precurved and straight sections 有权
标题翻译：耳蜗电极具有预先和直的部分
公开(公告)号：US08805546B2
公开(公告)日：2014-08-12
申请号：US11219824
申请日：2005-09-07
申请人： Fysh Dadd , Robert Briggs , Robert Cowan , Peter Gibson , Sharam Manouchehri , Claudia Tasche
发明人： Fysh Dadd , Robert Briggs , Robert Cowan , Peter Gibson , Sharam Manouchehri , Claudia Tasche
IPC分类号： A61N1/05
CPC分类号： A61N1/0541
摘要： An implantable electrode array for insertion into an implantee's body. The array comprises an elongate carrier having a proximal end and a distal end. A plurality of electrodes are supported by the carrier at respective longitudinally spaced locations thereon between the proximal end and the distal end. The carrier is comprised of at least a first portion that preferentially adopts a first at least partially curved configuration and at least a second portion that preferentially adopts a second different configuration to that of the first portion. The second portion is closer to the distal end than the first portion and both the first and second portions each have at least one electrode supported thereon.
摘要翻译：用于插入植入体的可植入电极阵列。阵列包括具有近端和远端的细长载体。多个电极由载体在近端和远端之间的相应的纵向间隔的位置处支撑。载体至少包括优先采用第一至少部分弯曲构型的第一部分和至少第二部分，该第二部分优先采用与第一部分不同的构型。第二部分比第一部分更靠近远端，并且第一部分和第二部分都具有支撑在其上的至少一个电极。

2. 发明申请

US20060085055A1 Cochlear electrode with precurved and straight sections 有权
标题翻译：耳蜗电极具有预先和直的部分
公开(公告)号：US20060085055A1
公开(公告)日：2006-04-20
申请号：US11219824
申请日：2005-09-07
申请人： Fysh Dadd , Robert Briggs , Robert Cowan , Peter Gibson , Shahram Manouchehri , Claudia Tasche
发明人： Fysh Dadd , Robert Briggs , Robert Cowan , Peter Gibson , Shahram Manouchehri , Claudia Tasche
IPC分类号： A61N1/05
CPC分类号： A61N1/0541
摘要： An implantable electrode array for insertion into an implantee's body. The array comprises an elongate carrier having a proximal end and a distal end. A plurality of electrodes are supported by the carrier at respective longitudinally spaced locations thereon between the proximal end and the distal end. The carrier is comprised of at least a first portion that preferentially adopts a first at least partially curved configuration and at least a second portion that preferentially adopts a second different configuration to that of the first portion. The second portion is closer to the distal end than the first portion and both the first and second portions each have at least one electrode supported thereon.
摘要翻译：用于插入植入体的可植入电极阵列。阵列包括具有近端和远端的细长载体。多个电极由载体在近端和远端之间的相应的纵向间隔的位置处支撑。载体至少包括优先采用第一至少部分弯曲构型的第一部分和至少第二部分，该第二部分优先采用与第一部分不同的构型。第二部分比第一部分更靠近远端，并且第一部分和第二部分都具有支撑在其上的至少一个电极。

3. 发明申请

US20130268043A1 Stimulating Device 审中-公开
标题翻译：刺激装置
公开(公告)号：US20130268043A1
公开(公告)日：2013-10-10
申请号：US13659531
申请日：2012-10-24
申请人： Claudia Tasche , John Parker , Dusan Milojevic , Colin Irwin
发明人： Claudia Tasche , John Parker , Dusan Milojevic , Colin Irwin
IPC分类号： A61N1/05
CPC分类号： A61N1/0551 , A61M5/14276 , A61M2205/05 , A61M2210/0662 , A61N1/0541 , A61N1/36036
摘要： An implantable apparatus, such as a inner ear prosthetic hearing implant, and a method for delivering neuron firing threshold-reducing stimuli to a neural network of an implantee are provided. The apparatus comprises a stimulator device that generates stimulation signals, and an electrode array that receives the stimulation signals and delivers the stimuli to the neural network of the implantee in response to the signals. The stimuli delivered to the implantee facilitates and/or controls the production and/or release of naturally occurring agents into the neural network to reduce the firing thresholds of neurons.
摘要翻译：提供了可植入装置，例如内耳假体听力植入物，以及用于将神经元激发阈值降低刺激递送到植入物的神经网络的方法。该装置包括产生刺激信号的刺激器装置和接收刺激信号的电极阵列，并响应于该信号将刺激递送给植入者的神经网络。传递给植入者的刺激物有助于和/或控制将天然存在的药剂产生和/或释放到神经网络中以降低神经元的触发阈值。

4. 发明申请

US20100030130A1 PHARMACEUTICAL INTERVENTION FOR MODULATION OF NEURAL PLASTICITY 审中-公开
标题翻译：神经胶质调节药物干预
公开(公告)号：US20100030130A1
公开(公告)日：2010-02-04
申请号：US12415812
申请日：2009-03-31
申请人： John L. Parker , Dusan Milojevic , Claudia Tasche
发明人： John L. Parker , Dusan Milojevic , Claudia Tasche
IPC分类号： A61F11/04 , A61N1/36 , A61M37/00
CPC分类号： A61N1/36036 , A61F11/00 , A61M5/14276 , A61M2205/05 , A61M2210/0662 , A61N1/0541
摘要： A stimulating medical device. The stimulating medical device comprises: a stimulating assembly implantable proximate to a recipient's neural system, the assembly having at least one agent delivery port and a plurality of electrical contacts; an electrical stimulation controller configured to generate electrical stimulation signals for application the neural system via one or more of the plurality of electrical contacts; a pharmaceutical agent source configured to provide a plasticity modulating agent to the at least one delivery port for application to the neural system; and a pharmaceutical agent controller configured to control one or more of the pharmaceutical agent source and the at least one delivery port to cause selective application of the plasticity modulating agent to the neural system to at least one of reinforce and activate one or more neural pathways within the system.
摘要翻译：刺激性医疗器械。刺激性医疗装置包括：可接近接收者的神经系统植入的刺激组件，所述组件具有至少一个药剂输送口和多个电触头; 电刺激控制器，被配置为产生电刺激信号，用于经由所述多个电触点中的一个或多个施加所述神经系统; 药剂源，被配置为向所述至少一个递送端口提供可塑性调节剂以供应用于所述神经系统; 以及药剂控制器，其被配置为控制所述药剂源和所述至少一个递送端口中的一个或多个，以引起对所述神经系统的所述可塑性调节剂的选择性应用至少一种以增强和激活所述神经系统内的一个或多个神经通路系统。

5. 发明申请

US20160015975A1 Cochlear Implant Stimulation 有权
标题翻译：人工耳蜗刺激
公开(公告)号：US20160015975A1
公开(公告)日：2016-01-21
申请号：US14799764
申请日：2015-07-15
申请人： Wolfram Frederik Dueck , Nicholas Charles Kendall Pawsey , Peter Raymond Sibary , Claudia Tasche
发明人： Wolfram Frederik Dueck , Nicholas Charles Kendall Pawsey , Peter Raymond Sibary , Claudia Tasche
IPC分类号： A61N1/36 , A61N1/05
CPC分类号： A61N1/36032 , A61N1/0541 , A61N1/36036
摘要： Presented herein are trans-modiolar stimulation techniques in which stimulation current is sourced (delivered) by at least one intra-cochlear stimulating contact and is sunk at a group of other intra-cochlear stimulating contacts. The group of other infra-cochlear stimulating contacts is positioned (located) across a section of the recipient's modiolus from the intra-cochlear stimulating contact that sources the stimulation. As such, stimulation current generally passes through the modiolus to stimulate spiral ganglion cells and evoke a hearing percept.
摘要翻译：这里提出的是反式模式刺激技术，其中通过至少一个耳蜗内刺激接触来源（递送）刺激电流并且沉没在一组其他耳蜗内刺激接触处。其他耳蜗刺激接触的组被定位（定位）穿过来自刺激的耳蜗内刺激接触的接受者的一部分。因此，刺激电流通常通过脉络膜刺激螺旋神经节细胞并引起听觉感知。

6. 发明申请

US20100030301A1 ELECTRICAL STIMULATION FOR MODULATION OF NEURAL PLASTICITY 审中-公开
标题翻译：用于调节神经塑性的电刺激
公开(公告)号：US20100030301A1
公开(公告)日：2010-02-04
申请号：US12415769
申请日：2009-03-31
申请人： John L. Parker , Dusan Milojevic , Claudia Tasche
发明人： John L. Parker , Dusan Milojevic , Claudia Tasche
IPC分类号： A61F11/04 , A61N1/36
CPC分类号： A61N1/36036 , A61N1/0541
摘要： A stimulating medical device. The stimulating medical device comprises a plurality of electrical contacts implantable proximate to a recipient's neural system; and an electrical stimulation controller configured to generate and apply plasticity modulating electrical stimulation signals to the recipient's neural system via one or more of the plurality of electrical contacts, the plasticity modulating signals configured to facilitate one or more of the production and release of naturally occurring neurotrophic agents within the recipient's neural system.
摘要翻译：刺激性医疗器械。刺激性医疗装置包括可接近接受者的神经系统植入的多个电触点; 以及电刺激控制器，其被配置为通过所述多个电触点中的一个或多个生成并将可塑性调制电刺激信号应用于所述受体的神经系统，所述可塑性调节信号被配置为促进天然存在的神经营养的一种或多种生产和释放接受者神经系统内的代理。

7. 发明申请

US20050171579A1 Stimulating device 审中-公开
标题翻译：刺激装置
公开(公告)号：US20050171579A1
公开(公告)日：2005-08-04
申请号：US11045624
申请日：2005-01-28
申请人： Claudia Tasche , John Parker , Dusan Milojevic , Colin Irwin
发明人： Claudia Tasche , John Parker , Dusan Milojevic , Colin Irwin
IPC分类号： A61N1/36 , A61N1/18
CPC分类号： A61N1/0551 , A61M5/14276 , A61M2205/05 , A61M2210/0662 , A61N1/0541 , A61N1/36036
摘要： An implantable apparatus, such as a inner ear prosthetic hearing implant, and a method for delivering neuron firing threshold-reducing stimuli to a neural network of an implantee are provided. The apparatus comprises a stimulator device that generates stimulation signals, and an electrode array that receives the stimulation signals and delivers the stimuli to the neural network of the implantee in response to the signals. The stimuli delivered to the implantee facilitates and/or controls the production and/or release of naturally occurring agents into the neural network to reduce the firing thresholds of neurons.
摘要翻译：提供了可植入装置，例如内耳假体听力植入物，以及用于将神经元激发阈值降低刺激递送到植入物的神经网络的方法。该装置包括产生刺激信号的刺激器装置和接收刺激信号的电极阵列，并响应于该信号将刺激递送给植入者的神经网络。传递给植入者的刺激物有助于和/或控制将天然存在的药剂产生和/或释放到神经网络中以降低神经元的触发阈值。

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