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1. 发明申请

US20130065051A1 Styrenic Block Copolymer-Based Composition with Enhanced Flame-Retardant Properties 审中-公开
标题翻译：具有增强阻燃性能的苯乙烯嵌段共聚物基组合物
公开(公告)号：US20130065051A1
公开(公告)日：2013-03-14
申请号：US13640687
申请日：2010-04-14
申请人： Given Jing Chen , Bin Li , Geoffrey D. Brown , Xiangyang Tai , Tong Wu , Kawai Peter Pang , Yongyong Yang , Robert F. Eaton , Manish Mundra
发明人： Given Jing Chen , Bin Li , Geoffrey D. Brown , Xiangyang Tai , Tong Wu , Kawai Peter Pang , Yongyong Yang , Robert F. Eaton , Manish Mundra
IPC分类号： C09K21/14 , D02G3/36
CPC分类号： C08K5/52 , C08K5/34928 , C08K5/5205 , C08K5/523 , C08L53/00 , Y10T428/2933 , C08L53/025
摘要： Halogen-free, flame-retardant thermoplastic compositions that include a styrenic block copolymer, a low-melting, phosphorus-based flame retardant having a melting temperature no higher than 170° C., and a blend of solid intumescent phosphorus and nitrogen-containing flame retardants. The blend of solid intumescent flame retardants include at least two phosphorous and nitrogen-containing phosphoric acid salts that synergistically enhance the flame-retardant properties of the compositions relative to compositions that include other flame-retardant packages.
摘要翻译：不含卤素的阻燃热塑性组合物，其包括苯乙烯嵌段共聚物，熔融温度不高于170℃的低熔点磷系阻燃剂，以及固体膨胀型磷和含氮火焰的共混物阻滞剂。固体膨胀型阻燃剂的混合物包括至少两种含磷和含氮磷酸盐，其相对于包括其它阻燃包装的组合物协同增强组合物的阻燃性能。

2. 发明申请

US20120238664A1 Thermoplastic Polymer Blends Comprising Crosslinked Polar Olefin Polymers in a Thermoplastic Polyurethane Matrix 审中-公开
标题翻译：热塑性聚氨酯基质中包含交联极性烯烃聚合物的热塑性聚合物共混物
公开(公告)号：US20120238664A1
公开(公告)日：2012-09-20
申请号：US13512718
申请日：2009-12-11
申请人： Wilson Xiao Wei Yan , Given Jing Chen , Tong Wu , Lotus Hua Huang , David Hong Fei Guo , Jeffrey M. Cogen , Will Wei Chao Gu
发明人： Wilson Xiao Wei Yan , Given Jing Chen , Tong Wu , Lotus Hua Huang , David Hong Fei Guo , Jeffrey M. Cogen , Will Wei Chao Gu
IPC分类号： C08L75/04 , C08K5/524
CPC分类号： C08L75/04 , C08K3/22 , C08K5/523 , C08K5/54 , C08L23/02 , C08L23/0853 , C08L31/04 , C08L63/04 , C08L2201/02 , C08L2666/20 , C08L2666/22 , C08L2666/04
摘要： Polymer blends comprising a first phase comprising a thermoplastic polyurethane matrix and a second phase comprising a crosslinked polar olefin polymer are provided. The first phase is a continuous phase and the second phase can be co-continuous with the first phase, or dispersed as a non-continuous phase in the first phase. The first phase further comprises a metal hydroxide flame retardant and an organic flame retardant. The second phase further includes a metal hydroxide which is coupled to the olefin polymer via a silane coupling agent.
摘要翻译：提供包含包含热塑性聚氨酯基质的第一相和包含交联的极性烯烃聚合物的第二相的聚合物共混物。第一相是连续相，第二相可以与第一相共同连续，或者在第一相中作为非连续相分散。第一阶段还包括金属氢氧化物阻燃剂和有机阻燃剂。第二相还包括通过硅烷偶联剂与烯烃聚合物偶联的金属氢氧化物。

3. 发明申请

US20100331413A1 Therapeutic Formulations Based on Asiatic Acid and Selected Salts Thereof 有权
标题翻译：基于亚洲酸及其选择盐的治疗配方
公开(公告)号：US20100331413A1
公开(公告)日：2010-12-30
申请号：US12811477
申请日：2009-01-08
申请人： Ying Liu , Quanhai Liu , Yan Qin , Tong Wu , Zhiru Xu , Min-yu Liu , Fei Li , Yan Li , Michael J. Newman
发明人： Ying Liu , Quanhai Liu , Yan Qin , Tong Wu , Zhiru Xu , Min-yu Liu , Fei Li , Yan Li , Michael J. Newman
IPC分类号： A61K31/19 , C07C62/32 , C07C233/00 , C07C69/74 , C07H13/02 , A61P11/00 , A61P3/10 , A61P1/00 , A61P17/06 , A61P19/02
CPC分类号： C07J63/008
摘要： A highly pure asiaticoside and a pharmaceutical grade asiatic acid can be prepared, along with salts of asiatic acid, for use in formulating therapeutic compositions that are suitable for treating arthritis, psoriasis and other inflammatory diseases, as well as pulmonary fibrosis, diabetic nephropathy, and other fibrotic diseases.
摘要翻译：可以制备高纯度积雪草苷和药物级积雪草酸以及积雪草酸盐，用于配制适合于治疗关节炎，牛皮癣和其它炎性疾病以及肺纤维化，糖尿病性肾病和其他纤维化疾病。

4. 发明授权

US07598385B2 Asymmetric cyanine fluorescent dyes 有权
标题翻译：不对称花青荧光染料
公开(公告)号：US07598385B2
公开(公告)日：2009-10-06
申请号：US11967991
申请日：2007-12-31
申请人： Xiaojun Peng , Tong Wu , Jiangli Fan , Shiguo Sun , Bingshuai Wang , Bing Xu , Jianhui Shao
发明人： Xiaojun Peng , Tong Wu , Jiangli Fan , Shiguo Sun , Bingshuai Wang , Bing Xu , Jianhui Shao
IPC分类号： C07D215/12
CPC分类号： C09B23/06 , C09B23/083 , Y10S436/80 , Y10T436/141111 , Y10T436/145555
摘要： The present disclosure provides the asymmetric cyanine fluorescent dyes of formula I in which X, n, R1, R2, R3, R4, R5 and Y− are as defined in the specification. The present disclosure also provides conjugates of the fluorescent dyes, methods for preparation thereof, compositions comprising the fluorescent dyes, and methods for staining biological samples using the fluorescent dyes and compositions thereof.
摘要翻译：本发明提供式I的不对称花青荧光染料，其中X，n，R 1，R 2，R 3，R 4，R 5和Y-如说明书中所定义。本公开还提供了荧光染料的缀合物，其制备方法，包含荧光染料的组合物，以及使用荧光染料及其组合物染色生物样品的方法。

5. 发明申请

US20090322865A1 IMAGE CAPTURE CONTROL FOR IN VIVO AUTONOMOUS CAMERA 有权
标题翻译：自动摄像机的图像捕获控制
公开(公告)号：US20090322865A1
公开(公告)日：2009-12-31
申请号：US12543508
申请日：2009-08-19
申请人： Kang-Huai Wang , Tong Wu
发明人： Kang-Huai Wang , Tong Wu
IPC分类号： H04N7/18 , H04N5/228
CPC分类号： H04N5/232 , A61B1/00009 , A61B1/00016 , A61B1/0002 , A61B1/00029 , A61B1/00032 , A61B1/00036 , A61B1/041 , A61B1/0684 , A61B5/0031 , A61B5/01 , A61B5/03 , A61B5/073 , A61B5/14539 , A61B5/7232 , H04N19/105 , H04N19/137 , H04N19/172 , H04N19/423 , H04N2005/2255
摘要： Systems and methods are provided for motion detection and capture control of video data from a capsule camera system having an on-board storage. The capsule camera system moves through the GI tract under the action of peristalsis and records images of the intestinal walls. The capsule's movement is episodic and jerky. The capacity of the on-board storage is limited. In order to avoid unnecessary capture of images when the capsule camera moves very slowly or stalls, motion detection technique is utilized to help control image capture. Furthermore, an adaptive capture control is disclosed that automatically adjusts the threshold level of capture control to maintain proper image capture. The invented capture control also conserves precious battery power by eliminating capture of unnecessary images when the capsule camera moves too slowly or stalls. The present invention of image capture control and threshold update is also applicable to a capsule camera system having a wireless transmitter instead of an on-board storage.
摘要翻译：提供了系统和方法用于具有车载存储的胶囊相机系统的视频数据的运动检测和捕获控制。胶囊相机系统在蠕动作用下通过胃肠道移动，并记录肠壁的图像。胶囊的运动是偶然和剧烈的。机载存储的容量有限。为了避免在胶囊相机移动非常缓慢或停止时不必要地捕获图像，运动检测技术被用于帮助控制图像捕获。此外，公开了自适应捕获控制，其自动调整捕获控制的阈值水平以保持适当的图像捕获。本发明的捕获控制还通过在胶囊相机移动太慢或失速时消除不必要的图像的捕获来节省宝贵的电池电量。图像捕获控制和阈值更新的本发明也适用于具有无线发射器而不是机载存储的胶囊相机系统。

6. 发明授权

US06821957B2 Vectors and methods for immunization or therapeutic protocols 失效
标题翻译：载体和免疫方法或治疗方案
公开(公告)号：US06821957B2
公开(公告)日：2004-11-23
申请号：US09965101
申请日：2001-09-26
申请人： Arthur M. Krieg , Heather L. Davis , Tong Wu , Schorr Joachim
发明人： Arthur M. Krieg , Heather L. Davis , Tong Wu , Schorr Joachim
IPC分类号： A61K4800
CPC分类号： C12N15/86 , A61K39/12 , A61K39/292 , A61K39/39 , A61K48/00 , A61K2039/53 , A61K2039/55561 , A61K2039/57 , C12N2710/10343 , C12N2730/10134
摘要： The present invention shows that DNA vaccine vectors can be improved by removal of CpG-N motifs and optional addition of CpG-S motifs. In addition, for high and long-lasting levels of expression, the optimized vector should include a promoter/enhancer that is not down-regulated by the cytokines induced by the immunostimulatory CpG motifs. Vectors and methods of use for immununostimulation are provided herein. The invention also provides improved gene therapy vectors by determining the CpG-N and CpG-S motifs present in the construct, removing stimulatory CpG (CpG-S) motifs and/or inserting neutralizing CpG (CpG-N) motifs, thereby producing a nucleic acid construct providing enhanced expression of the therapeutic polypeptide. Methods of use for such vectors are also included herein.
摘要翻译：本发明显示可以通过除去CpG-N基序和任选添加CpG-S基序来改善DNA疫苗载体。此外，对于高和长期的表达水平，优化的载体应包括不被免疫刺激性CpG基序诱导的细胞因子下调的启动子/增强子。本文提供了用于免疫刺激的载体和方法。本发明还通过确定构建体中存在的CpG-N和CpG-S基序，除去刺激性CpG（CpG-S）基序和/或插入中和CpG（CpG-N）基序，从而产生核酸提供治疗性多肽的增强的表达。这些载体的使用方法也包括在本文中。

7. 发明授权

US08909041B2 Method and apparatus for determining an optical signal-to-noise ratio (OSNR) penalty 有权
标题翻译：用于确定光信噪比（OSNR）罚分的方法和装置
公开(公告)号：US08909041B2
公开(公告)日：2014-12-09
申请号：US13486821
申请日：2012-06-01
申请人： Yabin Ye , Tong Wu , Sen Zhang
发明人： Yabin Ye , Tong Wu , Sen Zhang
IPC分类号： H04B10/00 , H04B10/079
CPC分类号： H04B10/07953
摘要： A method for determining an optical signal-to-noise ratio penalty as a measure for a quality of an optical signal transmitted via an optical link between a source optical node and a destination optical node in an optical network, the method includes collecting information of the optical link; determining a configuration parameter Pconf of the optical link based on the information of the optical link; adjusting the configuration parameter Pconf to an adjusted configuration parameter P′conf according to linear impairments in the optical link; and determining the optical signal-to-noise ratio penalty based on a non-linear function of the adjusted configuration parameter P′conf, the non-linear function accounting for non-linear impairments in the optical link.
摘要翻译：一种用于确定光信噪比损失的方法，用作通过光网络中的源光节点和目的地光节点之间的光链路传输的光信号的质量的量度，所述方法包括：光链路; 基于所述光链路的信息确定所述光链路的配置参数Pconf; 根据光链路中的线性损伤将配置参数Pconf调整到经调整的配置参数P'conf; 以及基于所调整的配置参数P'conf的非线性函数来确定所述光信噪比损失，所述非线性函数考虑所述光链路中的非线性损伤。

8. 发明授权

US08742167B2 Therapeutic formulations based on asiatic acid and selected salts thereof 有权
标题翻译：基于积雪草酸及其选择的盐的治疗剂型
公开(公告)号：US08742167B2
公开(公告)日：2014-06-03
申请号：US12811477
申请日：2009-01-08
申请人： Ying Liu , Quanhai Liu , Yan Qin , Tong Wu , Zhiru Xu , Min-yu Liu , Fei Li , Yan Li , Michael J. Newman
发明人： Ying Liu , Quanhai Liu , Yan Qin , Tong Wu , Zhiru Xu , Min-yu Liu , Fei Li , Yan Li , Michael J. Newman
IPC分类号： C07C61/29
CPC分类号： C07J63/008
摘要： A highly pure asiaticoside and a pharmaceutical grade asiatic acid can be prepared, along with salts of asiatic acid, for use in formulating therapeutic compositions that are suitable for treating arthritis, psoriasis and other inflammatory diseases, as well as pulmonary fibrosis, diabetic nephropathy, and other fibrotic diseases.
摘要翻译：可以制备高纯度积雪草苷和药物级积雪草酸以及积雪草酸盐，用于配制适合于治疗关节炎，牛皮癣和其它炎性疾病以及肺纤维化，糖尿病性肾病和其他纤维化疾病。

9. 发明申请

US20130028597A1 METHOD AND APPARATUS FOR DETERMINING AN OPTICAL SIGNAL-TO-NOISE RATIO (OSNR) PENALTY 有权
标题翻译：用于确定光信号噪声比（OSNR）罚款的方法和装置
公开(公告)号：US20130028597A1
公开(公告)日：2013-01-31
申请号：US13486821
申请日：2012-06-01
申请人： Yabin Ye , Tong Wu , Sen Zhang
发明人： Yabin Ye , Tong Wu , Sen Zhang
IPC分类号： H04B10/08
CPC分类号： H04B10/07953
摘要： A method for determining an optical signal-to-noise ratio penalty as a measure for a quality of an optical signal transmitted via an optical link between a source optical node and a destination optical node in an optical network, the method includes collecting information of the optical link; determining a configuration parameter Pconf of the optical link based on the information of the optical link; adjusting the configuration parameter Pconf to an adjusted configuration parameter P′conf according to linear impairments in the optical link; and determining the optical signal-to-noise ratio penalty based on a non-linear function of the adjusted configuration parameter P′conf, the non-linear function accounting for non-linear impairments in the optical link.
摘要翻译：一种用于确定光信噪比损失的方法，用作通过光网络中的源光节点和目的地光节点之间的光链路传输的光信号的质量的量度，所述方法包括：光链路; 基于所述光链路的信息确定所述光链路的配置参数Pconf; 根据光链路中的线性损伤将配置参数Pconf调整到经调整的配置参数P'conf; 以及基于所调整的配置参数P'conf的非线性函数来确定所述光信噪比损失，所述非线性函数考虑所述光链路中的非线性损伤。

10. 发明授权

US07792344B2 Image capture control for in vivo autonomous camera 有权
标题翻译：用于体内自主摄像机的图像捕获控制
公开(公告)号：US07792344B2
公开(公告)日：2010-09-07
申请号：US12543508
申请日：2009-08-19
申请人： Kang-Huai Wang , Tong Wu
发明人： Kang-Huai Wang , Tong Wu
IPC分类号： G06K9/00
CPC分类号： H04N5/232 , A61B1/00009 , A61B1/00016 , A61B1/0002 , A61B1/00029 , A61B1/00032 , A61B1/00036 , A61B1/041 , A61B1/0684 , A61B5/0031 , A61B5/01 , A61B5/03 , A61B5/073 , A61B5/14539 , A61B5/7232 , H04N19/105 , H04N19/137 , H04N19/172 , H04N19/423 , H04N2005/2255
摘要： Systems and methods are provided for motion detection and capture control of video data from a capsule camera system having an on-board storage. The capsule camera system moves through the GI tract under the action of peristalsis and records images of the intestinal walls. The capsule's movement is episodic and jerky. The capacity of the on-board storage is limited. In order to avoid unnecessary capture of images when the capsule camera moves very slowly or stalls, motion detection technique is utilized to help control image capture. Furthermore, an adaptive capture control is disclosed that automatically adjusts the threshold level of capture control to maintain proper image capture. The invented capture control also conserves precious battery power by eliminating capture of unnecessary images when the capsule camera moves too slowly or stalls. The present invention of image capture control and threshold update is also applicable to a capsule camera system having a wireless transmitter instead of an on-board storage.
摘要翻译：提供了系统和方法用于具有车载存储的胶囊相机系统的视频数据的运动检测和捕获控制。胶囊相机系统在蠕动作用下通过胃肠道移动，并记录肠壁的图像。胶囊的运动是偶然和剧烈的。机载存储的容量有限。为了避免在胶囊相机移动非常缓慢或停止时不必要地捕获图像，运动检测技术被用于帮助控制图像捕获。此外，公开了自适应捕获控制，其自动调整捕获控制的阈值水平以保持适当的图像捕获。本发明的捕获控制还通过在胶囊相机移动太慢或失速时消除不必要的图像的捕获来节省宝贵的电池电量。图像捕获控制和阈值更新的本发明也适用于具有无线发射器而不是机载存储的胶囊相机系统。

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