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1. 发明授权

US08350222B2 Multimodality imaging 有权
标题翻译：多模态成像
公开(公告)号：US08350222B2
公开(公告)日：2013-01-08
申请号：US12939036
申请日：2010-11-03
申请人： Alexander Hans Vija , Steffen Kappler , Guenter Hahn
发明人： Alexander Hans Vija , Steffen Kappler , Guenter Hahn
IPC分类号： G01T1/164
CPC分类号： A61B6/5235 , A61B6/032 , A61B6/037 , A61B6/4241 , A61B6/4258 , A61B6/4266
摘要： An imaging system includes interleaved emission detectors and transmission detectors. Emission detectors and transmission detectors can be interleaved along the axis of relative patient motion. Emission detectors and transmission detectors can be interleaved orthogonal to the axis of relative patient motion. Emission detectors can be single photon emission computed tomography detectors and the transmission detectors can be x-ray computed tomography detectors.
摘要翻译：成像系统包括交错发射检测器和传输检测器。发射检测器和传输检测器可以沿着相对患者运动的轴线交错。发射检测器和传输检测器可以与相对患者运动的轴线正交交错。发射检测器可以是单光子发射计算机断层摄影检测器，并且传输检测器可以是X射线计算机断层摄影检测器。

2. 发明申请

US20100014730A1 Multimodal Image Reconstruction 有权
标题翻译：多模式图像重构
公开(公告)号：US20100014730A1
公开(公告)日：2010-01-21
申请号：US12369159
申请日：2009-02-11
申请人： Guenter Hahn , Alexander Hans Vija
发明人： Guenter Hahn , Alexander Hans Vija
IPC分类号： G06K9/00
CPC分类号： G06T5/001 , G06T5/50 , G06T2207/10072 , G06T2207/10084 , G06T2207/20212 , G06T2207/20216 , G06T2207/20221 , G06T2207/20224 , G06T2207/30016
摘要： Computer-implemented methods of reconstructing an image object for a measured object in object space from image data in data space include causing a computer to execute instructions for providing zonal information separating the object space into at least two zones, providing at least two zonal image objects, each zonal image object being associated with one of the at least two zones, reconstructing the image object using a data model derived from forward projecting the zonal image objects into data space, wherein the contribution of each zonal image object to the data model is weighted according to a zonal scaling factor, and outputting the image object.
摘要翻译：计算机实现的方法从数据空间中的图像数据重建对象空间中的测量对象的图像对象包括使计算机执行用于提供将对象空间分成至少两个区域的区域信息的指令，提供至少两个区带图像对象每个区域图像对象与至少两个区域中的一个区域相关联，使用从向前投影区域图像对象导出的数据模型重建图像对象到数据空间，其中每个区域图像对象对数据模型的贡献被加权根据区域缩放因子，并输出图像对象。

3. 发明申请

US20110089327A1 Multimodality Imaging 有权
标题翻译：多模态成像
公开(公告)号：US20110089327A1
公开(公告)日：2011-04-21
申请号：US12939036
申请日：2010-11-03
申请人： Alexander Hans Vija , Steffen Kappler , Guenter Hahn
发明人： Alexander Hans Vija , Steffen Kappler , Guenter Hahn
IPC分类号： G01T1/166 , A61B6/03
CPC分类号： A61B6/5235 , A61B6/032 , A61B6/037 , A61B6/4241 , A61B6/4258 , A61B6/4266
摘要： An imaging system includes interleaved emission detectors and transmission detectors. Emission detectors and transmission detectors can be interleaved along the axis of relative patient motion. Emission detectors and transmission detectors can be interleaved orthogonal to the axis of relative patient motion. Emission detectors can be single photon emission computed tomography detectors and the transmission detectors can be x-ray computed tomography detectors.
摘要翻译：成像系统包括交错发射检测器和传输检测器。发射检测器和传输检测器可以沿着相对患者运动的轴线交错。发射检测器和传输检测器可以与相对患者运动的轴线正交交错。发射检测器可以是单光子发射计算机断层摄影检测器，并且传输检测器可以是X射线计算机断层摄影检测器。

4. 发明授权

US07863574B2 Multimodality imaging system 有权
标题翻译：多模态成像系统
公开(公告)号：US07863574B2
公开(公告)日：2011-01-04
申请号：US12503963
申请日：2009-07-16
申请人： Guenter Hahn , Alexander Hans Vija
发明人： Guenter Hahn , Alexander Hans Vija
IPC分类号： G01T1/166
CPC分类号： G06T5/001 , G06T5/50 , G06T2207/10072 , G06T2207/10084 , G06T2207/20212 , G06T2207/20216 , G06T2207/20221 , G06T2207/20224 , G06T2207/30016
摘要： A system and method is provided for performing multimodal imaging of an object. The system and method includes performing spatio-temporal detection of transmission CT data of a fan X-ray beam, performing, and simultaneously with the spatio-temporal detection of transmission CT data, spatio-temporal detection of emission nuclear imaging data emitted from the object with a propagation direction across the propagation direction of the fan X-ray beam. The system and method further includes identifying at least two zones in the object based on the transmission CT data, reconstructing an image object from the emission nuclear imaging data under the constraint that respective portions of detected nuclear events are associated with selected zones, and outputting data representative of the image object.
摘要翻译：提供了一种用于执行对象的多模式成像的系统和方法。该系统和方法包括执行风扇X射线束的透射CT数据的空间 - 时间检测，并且与透射CT数据的时空检测同时执行从物体发射的发射核成像数据的时空检测沿着风扇X射线束的传播方向的传播方向。所述系统和方法还包括基于所述传输CT数据来识别所述对象中的至少两个区域，在所检测的核事件的相应部分与所选择的区域相关联的约束下，从所述发射核成像数据重建图像对象，以及输出数据代表图像对象。

5. 发明申请

US20100102239A1 MULTIMODALITY IMAGING SYSTEM 有权
标题翻译：多重成像系统
公开(公告)号：US20100102239A1
公开(公告)日：2010-04-29
申请号：US12503963
申请日：2009-07-16
申请人： Guenter Hahn , Alexander Hans Vija
发明人： Guenter Hahn , Alexander Hans Vija
IPC分类号： G01T1/166 , H05G1/60
CPC分类号： G06T5/001 , G06T5/50 , G06T2207/10072 , G06T2207/10084 , G06T2207/20212 , G06T2207/20216 , G06T2207/20221 , G06T2207/20224 , G06T2207/30016
摘要： The application discloses multimodality imaging systems that include a gantry with a stationary unit and a rotating unit rotatable around a rotation axis and providing an opening extending along the rotation axis through which a subject is insertable, a support table coupled to the stationary unit for supporting a subject, a table drive unit coupled to the support table for translating the support table in a direction extending along the rotation axis, and a CT source coupled to the rotating unit, the CT source being configured to emit a fan beam through the opening, a CT detector coupled to the rotating unit opposite the CT source, the CT source being configured to detect the fan beam, a nuclear imaging detector coupled to the rotating unit, the nuclear imaging detector being configured to detect nuclear radiation emitted from within the opening in a direction differing from a propagation direction of the fan beam.The multimodality imaging systems include further a control unit configured to, during operation of the multimodality imaging system, cause the rotating unit to rotate with a revolution time of one second or less, and to control the translation of the support table such that the CT detector performs diagnostic quality CT imaging of the subject and the nuclear imaging detector performs a spiral scan of the subject, whereby the multimodality imaging system acquires spatio-temporally consistent transmission CT data and emission nuclear imaging data.
摘要翻译：本申请公开了一种多模式成像系统，其包括具有静止单元的台架和可围绕旋转轴线旋转的旋转单元，并且提供沿着旋转轴线延伸的开口，通过该旋转轴线可以插入对象;支撑台，其联接到固定单元，所述台面驱动单元联接到所述支撑台，用于沿着所述旋转轴线延伸的方向平移所述支撑台;以及CT源，其联接到所述旋转单元，所述CT源被配置为通过所述开口发射风扇梁， CT检测器，其耦合到与CT源相对的旋转单元，CT源被配置为检测风扇光束，耦合到旋转单元的核成像检测器，核成像检测器被配置为检测从内部的开口中发射的核辐射方向与扇形束的传播方向不同。多模态成像系统还包括控制单元，其被配置为在多模态成像系统的操作期间使旋转单元以一秒或更短的旋转时间旋转，并且控制支撑台的平移，使得CT检测器对被检体进行诊断质量CT成像，并且核成像检测器执行被检体的螺旋扫描，由此多模式成像系统获取空间 - 时间上一致的透射CT数据和发射核成像数据。

6. 发明授权

US09332907B2 Extracting application dependent extra modal information from an anatomical imaging modality for use in reconstruction of functional imaging data 有权
标题翻译：从解剖成像模式中提取与应用程序相关的附加模态信息，以用于功能成像数据的重建
公开(公告)号：US09332907B2
公开(公告)日：2016-05-10
申请号：US13852029
申请日：2013-03-28
申请人： Alexander Hans Vija
发明人： Alexander Hans Vija
IPC分类号： G06K9/00 , A61B5/00 , G06T11/00 , G06T7/00
CPC分类号： A61B5/0035 , G06T7/11 , G06T11/005 , G06T2207/10081 , G06T2207/30008 , G06T2207/30056 , G06T2207/30061
摘要： Segmentation is provided in multi-modal reconstruction of functional information. Rather than using HU values for segmentation, the HU values are converted into linear attenuation coefficients, such as in a μ-map (Mu map). The conversion uses different functions for different ranges of the HU values. Linear attenuation coefficients are less likely subject to variation by patient, protocol, or scanner. The resulting segmentation may be more consistent across various clinical settings, providing for more accurate multi-modal reconstruction.
摘要翻译：在功能信息的多模态重建中提供分段。不是使用HU值进行分割，而是将HU值转换为线性衰减系数，例如μ映射（Mu映射）。该转换对不同范围的HU值使用不同的功能。线性衰减系数不太可能受到患者，协议或扫描仪的变化。所得到的分割在各种临床设置中可以更一致，提供更准确的多模式重建。

7. 发明授权

US08958622B2 Efficient point spread function model for multi-channel collimator in photon imaging including extra-geometric photons 有权
标题翻译：包括超几何光子在内的光子成像中的多通道准直器的高效点扩散函数模型
公开(公告)号：US08958622B2
公开(公告)日：2015-02-17
申请号：US13888734
申请日：2013-05-07
申请人： Alexander Hans Vija , James C Sanders, III
发明人： Alexander Hans Vija , James C Sanders, III
IPC分类号： G06K9/00 , G06T11/00 , G01T1/164
CPC分类号： G06T11/005 , G01T1/164 , G01T1/1647 , G06T11/006 , G06T2211/416 , G06T2211/424
摘要： The point spread function of a multi-channel collimator is modeled in photon imaging. The geometric aperture used in the point spread function is expanded to account for penetration, scattering, and/or imperfections of the collimator. The aperture is broadened using a weight that is a function of the distance of the source from the collimator. Rather than scaling the point spread function itself, the geometric aperture used in the point spread function is scaled to an effective aperture. The distance and geometric constraints may be used to determine the geometric aperture, but an additional broadening occurs as a function of the distance to account for non-ideal photon paths of travel. This additional broadening may improve the fidelity with respect to measured data relative to purely geometric or Gaussian models.
摘要翻译：多通道准直器的点扩散函数在光子成像中被建模。在点扩散函数中使用的几何孔被扩展以考虑准直器的穿透，散射和/或缺陷。使用与源自准直器的距离的函数的重量来使孔径变宽。点扩展函数本身不是缩放，而是将点扩散函数中使用的几何孔径缩放到有效孔径。距离和几何约束可以用于确定几何孔径，但是作为考虑到非理想光子行进路径的距离的函数发生附加的变宽。这种额外的扩展可以提高相对于纯几何或高斯模型的测量数据的保真度。

8. 发明授权

US08650014B2 Controlling the number of iterations in image reconstruction 有权
标题翻译：控制图像重建中的迭代次数
公开(公告)号：US08650014B2
公开(公告)日：2014-02-11
申请号：US13313077
申请日：2011-12-07
申请人： Alexander Hans Vija , Amos Yahil
发明人： Alexander Hans Vija , Amos Yahil
IPC分类号： G06F17/10
CPC分类号： G06T11/006 , G06T2211/424
摘要： An iterative reconstruction method to reconstruct an object includes determining, in a series of iteration steps, updated objects, wherein each iteration step includes determining a data model from an input object, and determining a stop-criterion of the data model on the basis of a chi-square-gamma statistic. The method further includes determining that the stop-criterion of the data model has transitioned from being outside the limitation of a preset threshold value to being inside the limitation, ending the iterations, and selecting one of the updated objects to be the reconstructed object.
摘要翻译：用于重建对象的迭代重建方法包括在一系列迭代步骤中确定更新的对象，其中每个迭代步骤包括从输入对象确定数据模型，以及基于a的确定数据模型的停止准则卡方伽马统计量。该方法还包括确定数据模型的停止准则已经从超出预设阈值的限制转移到限制内部，结束迭代，并且选择更新后的对象中的一个作为重建对象。

9. 发明申请

US20120018645A1 Method and Apparatus to Optimize Injected Dose and Scan Time in SPECT Imaging 有权
标题翻译：在SPECT成像中优化注射剂量和扫描时间的方法和装置
公开(公告)号：US20120018645A1
公开(公告)日：2012-01-26
申请号：US13188014
申请日：2011-07-21
申请人： Alexander Hans Vija
发明人： Alexander Hans Vija
IPC分类号： G01T1/164
CPC分类号： A61B6/037 , A61B6/481 , A61B6/542 , A61B6/545
摘要： An apparatus and method are provided for optimizing an amount of radiation dose and acquisition time in cardiac Single Photon Emission Computed Tomography (SPECT) imaging. The apparatus and method include providing an organ, acquiring images of the organ at projected views. Then a projected view that projects the organ as an annulus is selected; a region of interest (ROI) is also selected in the projected view, wherein the ROI is in a lateral wall of the organ. An average count in the ROI is determined; and an image quality of a reconstructed image based on the average count is predicted.
摘要翻译：提供了一种用于在心脏单光子发射计算机断层扫描（SPECT）成像中优化辐射剂量和采集时间量的装置和方法。该装置和方法包括提供器官，以投影视图获取器官的图像。然后选择投影器官作为环的投影视图; 还在投影视图中选择感兴趣区域（ROI），其中ROI位于器官的侧壁中。确定ROI中的平均计数; 并且预测基于平均计数的重构图像的图像质量。

10. 发明授权

US08058601B2 Determining a multimodal pixon map for tomographic-image reconstruction 有权
标题翻译：确定断层图像重建的多峰像素图
公开(公告)号：US08058601B2
公开(公告)日：2011-11-15
申请号：US12369176
申请日：2009-02-11
申请人： Alexander Hans Vija , Amos Yahil
发明人： Alexander Hans Vija , Amos Yahil
IPC分类号： H01L27/00
CPC分类号： G06T5/001 , G06T5/50 , G06T2207/10072 , G06T2207/10084 , G06T2207/20212 , G06T2207/20216 , G06T2207/20221 , G06T2207/20224 , G06T2207/30016
摘要： A computer-implemented method includes causing a computer system to execute instructions for providing a first data set and a second data set, each derived from a common object, providing a first tomographic image object associated with the first data set providing a second tomographic image object associated with the second data set, generating a multimodal pixon map for pixon smoothing on the basis of the first data set, the first tomographic image object, the second data set, and the second tomographic image object, and outputting the multimodal pixon map.
摘要翻译：计算机实现的方法包括使计算机系统执行用于提供第一数据集和第二数据集的指令，每个从公共对象导出的数据集和第二数据集提供与提供第二断层图像对象的第一数据集相关联的第一断层图像对象与所述第二数据集相关联，基于所述第一数据集，所述第一断层图像对象，所述第二数据集和所述第二断层图像对象生成用于像素平滑的多模式像素图，并输出所述多峰像素图。

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