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1. 发明授权

US11762107B2 Protection of a gamma radiation detector with an optical modulator to modulate an amount of transmission between a gamma scintillator array and a first photodetector array 有权
公开(公告)号：US11762107B2
公开(公告)日：2023-09-19
申请号：US16470385
申请日：2017-12-21
申请人： KONINKLIJKE PHILIPS N.V.
发明人： Christiaan Kok
IPC分类号： A61B6/00 , G01T1/20 , G01T1/24 , G01T1/164 , G01T1/161 , G01T1/16 , A61B6/03
CPC分类号： G01T1/20181 , A61B6/03 , A61B6/032 , A61B6/035 , A61B6/037 , A61B6/42 , A61B6/4208 , A61B6/4233 , A61B6/4241 , A61B6/4258 , A61B6/4266 , A61B6/44 , A61B6/4429 , A61B6/4435 , A61B6/4441 , A61B6/4447 , G01T1/16 , G01T1/161 , G01T1/1603 , G01T1/164 , G01T1/1606 , G01T1/1611 , G01T1/1612 , G01T1/1614 , G01T1/1615 , G01T1/1617 , G01T1/1618 , G01T1/20 , G01T1/2002 , G01T1/2006 , G01T1/2008 , G01T1/2018 , G01T1/20183 , G01T1/20185 , G01T1/24 , G01T1/243 , G01T1/249
摘要： The invention relates to a combined detector (660) comprising a gamma radiation detector (100) and an X-ray radiation detector (661). The gamma radiation detector (100) comprises a gamma scintillator array (101x, y), an optical modulator (102) and a first photodetector array (103a, b) for detecting the first scintillation light generated by the gamma scintillator array (101x, y). The optical modulator (102) is disposed between the gamma scintillator array (101x, y) and the first photodetector array (103a, b) for modulating a transmission of the first scintillation light between the gamma scintillator array (101x, y) and the first photodetector array (103a, b). The optical modulator (102) comprises at least one optical modulator pixel having a cross sectional area (102′) in a plane that is perpendicular to the gamma radiation receiving direction (104). The cross sectional area of each optical modulator pixel (102′) is greater than or equal to the cross sectional area of each photodetector pixel (103′a, b).

2. 发明授权

US10845320B2 Scanning method and apparatus comprising a buoyancy material for scanning an underwater pipeline or a process vessel 有权
公开(公告)号：US10845320B2
公开(公告)日：2020-11-24
申请号：US16375359
申请日：2019-04-04
申请人： JOHNSON MATTHEY PUBLIC LIMITED COMPANY
发明人： Christopher Bowdon , Paul Featonby , James Stephen Howstan , Peter Jackson , Kenneth James , Emanuele Ronchi
IPC分类号： G01N23/04 , G01N23/046 , G01N23/06 , G01N23/083 , G01N23/087 , G01N23/18 , G01V5/00 , G01T1/164 , G01N9/24 , G01T1/20 , G21K1/02
CPC分类号： G01N23/18 , G01N9/24 , G01N23/04 , G01N23/046 , G01N23/06 , G01N23/083 , G01N23/087 , G01T1/164 , G01T1/2018 , G01V5/005 , G01V5/0016 , G21K1/02 , G01N2223/419 , G01N2223/5055
摘要： Disclosed herein are a scanning method and apparatus suitable for scanning a pipeline or process vessel in which a beam of gamma radiation from a source is emitted through the vessel to be detected by an array of detectors which are each collimated to detect radiation over a narrow angle relative to the width of the emitted radiation beam.

3. 发明申请

US20190184197A1 REAL-TIME MRI-PET-GUIDED RADIOTHERAPY SYSTEM WITH DOSE-DEPOSITION VERIFICATION 审中-公开
公开(公告)号：US20190184197A1
公开(公告)日：2019-06-20
申请号：US16322038
申请日：2017-07-31
申请人： ALBERTA HEALTH SERVICES
发明人： B. Gino FALLONE , Brad MURRAY
IPC分类号： A61N5/10 , G01T1/02 , G01T1/16
CPC分类号： A61N5/107 , A61N5/10 , A61N5/1049 , A61N5/1071 , A61N2005/1052 , A61N2005/1055 , A61N2005/1087 , G01T1/02 , G01T1/1603 , G01T1/164 , G01T1/166
摘要： A radiotherapy system is configured to determine in vivo dose deposition of a radiotherapy treatment beam. The system includes the following components. A bi-planar magnetic resonance imaging (MRI) apparatus comprising a pair of spaced apart magnets. One of the magnets includes a hole proximal the centre thereof. A treatment beam source configured to generate a radiotherapy reatment beam. The treatment beam source is positioned to transmit the treatment beam through the hole in the magnet. A patient support configured to position a patient with the system so that a treatment target is proximal the treatment beam. A Positron Emission Tomography (PET) detector configured to obtain PET data of the treatment beam impacting the patient. The PET detector is positioned so that a transverse section of the patient that includes the treatment target lies between opposing portions of the PET detector.

4. 发明申请

US20180217273A1 HYBRID PET / CT IMAGING DETECTOR 审中-公开
公开(公告)号：US20180217273A1
公开(公告)日：2018-08-02
申请号：US15748330
申请日：2016-07-28
申请人： KONINKLIJKE PHILIPS N.V.
发明人： Nathan SERAFINO , Dane PITTOCK , Jerome John GRIESMER , Marc Anthony CHAPPO
IPC分类号： G01T1/161 , G01T1/29 , G01T1/16 , G01T1/164 , G01T1/20 , A61B6/03 , A61B6/00
CPC分类号： G01T1/1617 , A61B6/032 , A61B6/037 , A61B6/4233 , A61B6/4241 , A61B6/4258 , A61B6/4266 , A61B6/4275 , A61B6/4291 , A61B6/4417 , A61B6/482 , A61B6/5205 , A61B6/5235 , A61B6/5282 , G01T1/1603 , G01T1/1615 , G01T1/164 , G01T1/2008 , G01T1/2018 , G01T1/2985
摘要： An imaging system (102) includes a detector array (104) with a ring (106) with a first layer (110i) that detects gamma radiation and X-ray radiation and a second layer (110N) that detects only gamma radiation, wherein the first and second layers are concentric closed rings. A method includes detecting gamma radiation with a first layer of a dual layer detector in response to imaging in PET mode, detecting gamma radiation with a second layer of the dual layer detector in response to imaging in PET mode, and generating PET image data with the radiation detected with the first and second layers. The method further includes detecting X-ray radiation with the first layer in response to imaging in CT mode and generating CT image data the radiation detected with the first layer. The method further includes displaying the image data. The imaging system allows a single gantry for both PET/CT imaging.

5. 发明申请

US20170371042A1 CONTRAST AGENT FOR OPTICAL IMAGING, USE THEREOF AND APPARATUS USING THE SAME 审中-公开
公开(公告)号：US20170371042A1
公开(公告)日：2017-12-28
申请号：US15684717
申请日：2017-08-23
申请人： KYUNGPOOK NATIONAL UNIVERSITY INDUSTRY- ACADEMIC COOPERATION FOUNDATION
发明人： Jeong Soo Yoo , Jeong Chan Park
IPC分类号： G01T1/164 , A61K51/12 , A61K49/18 , A61K51/04 , A61K49/00 , A61K51/02 , G01T7/08 , A61K51/10
CPC分类号： G01T1/164 , A61K49/0002 , A61K49/0067 , A61K49/1857 , A61K51/02 , A61K51/025 , A61K51/0491 , A61K51/1051 , A61K51/1244 , G01T1/2018 , G01T7/08
摘要： Provided are a contrast agent for optical imaging, a use thereof and an apparatus using the same. The contrast agent for optical imaging of the present disclosure allows optical imaging without requiring a fluorophore or a luminophore. As a result, the optical images can be acquired without changing the physicochemical properties of a substrate. The contrast agent for optical imaging of the present disclosure may be used as an optical/nuclear bimodal imaging contrast agent for many applications, and allows radiation therapy as well as monitoring of a therapeutic effect thereof through optical imaging at the same time. Further, when a fluorophore is attached thereto, light emission may be enhanced without energy input from outside since light is emitted from the fluorophore, thereby increasing luminescence intensity and improving tissue penetration.

6. 发明授权

US09625310B2 Systems and methods for sorting and summing signals from an imaging detector 有权
公开(公告)号：US09625310B2
公开(公告)日：2017-04-18
申请号：US14569002
申请日：2014-12-12
申请人： General Electric Company
发明人： Jean-Paul Bouhnik , Yaron Hefetz
IPC分类号： G01J1/42 , G01T1/164 , G01J1/44
CPC分类号： G01J1/4228 , G01J2001/442 , G01T1/164 , G01T1/1647
摘要： A system includes a detector and a main processing unit having an event processing module. The detector includes pixels to detect an event corresponding to photon absorption. The event processing module is configured to read event information for each event detected by each pixel of the detector in order of receipt from the detector and to compare an energy level value in the event information for each event to a predetermined range of energy level values. An event is counted when the energy level value is within the predetermined range of energy level values. For each event having an energy level below the predetermined range, the energy level value for a next consecutive event in the received event information is read and a combined energy level value of the event and the next consecutive event is determined as well as the pixel locations of the event and the next consecutive event. The combined energy level is counted as a single event when the combined energy level value is within a predetermined range of energy level values and when the pixel location for the event is near a pixel location for the next consecutive event. At least one pixel location is assigned to the single event.

7. 发明申请

US20160278735A1 Phantom system, use of the system, and imaging configuration having a phantom system 审中-公开
标题翻译： Phantom系统，系统的使用以及具有幻影系统的成像配置
公开(公告)号：US20160278735A1
公开(公告)日：2016-09-29
申请号：US15069991
申请日：2016-03-15
申请人： Bruker BioSpin MRI GmbH
发明人： Jochen Franke , Ulrich Heinen
IPC分类号： A61B6/00 , A61B6/03 , G01R33/58 , A61B5/055
CPC分类号： A61B6/583 , A61B5/055 , A61B6/032 , A61B6/037 , G01N23/04 , G01N23/046 , G01N2223/3035 , G01R33/58 , G01T1/164 , G01T7/00
摘要： A phantom system has a housing (2) with a lower part (3) having an opening in the z-direction and a cover part (4) for closing the opening of the housing (2). A first plate-shaped insert element (10a) has at least one depression (11a) for receiving a liquid substance. The lower part (3) and the cover part (4) delimit a cavity (5) with an insert area (8), which is constituted to receive the first insert element (10a). A first sealing element (14a) seals the first insert element (10a) against the cavity (5) and a fixing facility fixes the first insert element (10a) in the cavity (4) of the housing (2) in an operating state of the MPI phantom. The phantom permits good contrast in MPI, MRI, or μCT using liquid contrast media.
摘要翻译：幻影系统具有壳体（2），其具有在z方向上具有开口的下部（3）和用于封闭壳体（2）的开口的盖部分（4）。第一板状插入元件（10a）具有用于接收液体物质的至少一个凹部（11a）。下部（3）和盖部分（4）限定具有插入区域（8）的空腔（5），该插入区域被构造成接收第一插入元件（10a）。第一密封元件（14a）将第一插入元件（10a）密封抵靠空腔（5），并且固定装置将第一插入元件（10a）固定在壳体（2）的空腔（4）中，操作状态 MPI幻影。幻影允许使用液体造影剂的MPI，MRI或μCT中的良好对比度。

8. 发明申请

US20150331119A1 SCINTILLATION DETECTOR FOR IMPROVED PET PERFORMANCE 有权
标题翻译：用于改进PET性能的扫描检测器
公开(公告)号：US20150331119A1
公开(公告)日：2015-11-19
申请号：US14278912
申请日：2014-05-15
申请人： Kabushiki Kaisha Toshiba , Toshiba Medical Systems Corporation
发明人： Jerry Yanqi WANG , Kent C. Burr
IPC分类号： G01T1/29 , G01T1/161 , G01T1/208 , G01T1/164
CPC分类号： G01T1/161 , G01T1/164 , G01T1/1642 , G01T1/1644 , G01T1/208 , G01T1/29 , G01T1/2985
摘要： A radiation detector for a radiation imaging system, wherein the detector comprises photosensors, arranged to receive light emitted from an array of scintillator elements. The scintillator elements absorb radiation, such as gamma rays, and emit light. Using Anger arithmetic and crystal decoding, the position of each scintillation event is determined from the relative fractions of light detected by each of the photosensors. Selectively shaping the top surface, i.e., the surface closest to the photosensors, of each scintillator element in the array, the direction of light emission from each scintillator element can be optimized such that the fraction of light detected by each photosensor is optimally distinct for each position in the array of scintillator elements. The top surface of at least one of the scintillator element array is not parallel with the bottom surface of at least one of the scintillator.
摘要翻译：一种用于辐射成像系统的辐射检测器，其中所述检测器包括光电传感器，布置成接收从闪烁体元件阵列发射的光。闪烁体元件吸收辐射，例如γ射线，并发光。使用愤怒算术和晶体解码，每个闪烁事件的位置由每个光电传感器检测的光的相对分数确定。选择性地成形阵列中每个闪烁体元件的顶表面，即最接近光电传感器的表面，可以优化来自每个闪烁体元件的发光方向，使得由每个光电传感器检测到的光的分数对于每个光传感器最佳地是不同的闪烁体元件阵列中的位置。至少一个闪烁体元件阵列的顶表面与闪烁体中的至少一个的底表面不平行。

9. 发明授权

US09176237B2 Coincidence determination method and apparatus of PET device 有权
标题翻译： PET装置的一致性确定方法和装置
公开(公告)号：US09176237B2
公开(公告)日：2015-11-03
申请号：US13846443
申请日：2013-03-18
申请人： NATIONAL INSTITUTE OF RADIOLOGICAL SCIENCES
发明人： Eiji Yoshida , Taiga Yamaya
IPC分类号： G01T1/164 , G01T1/29
CPC分类号： G01T1/164 , G01T1/1647 , G01T1/2985
摘要： In a coincidence determination of a PET device, the PET device uses a scintillator of radioactive isotope containing background noise due to intrinsic radioactivity as a radiation detector. The PET device counts a pair of annihilation radiations that is assumed to occur from a same nuclide. The annihilation radiations are detected within a predetermined coincidence time window by a plurality of radiation detectors. The method includes determining a coincidence with a wide energy window that allows detecting the background noise due to intrinsic radioactivity as multiple coincidences; removing the multiple coincidences; and using an energy window narrower than the wide energy window to limit a coincidence event to a coincidence event in a photopeak from a positron nuclide only.
摘要翻译：在PET装置的重合判定中，PET装置使用由于内在放射性而含有背景噪声的放射性同位素的闪烁体作为放射线检测器。 PET装置计算出假定从同一个核素发生的一对湮灭辐射。通过多个辐射检测器在预定的重合时间窗内检测湮灭辐射。该方法包括确定与宽能量窗口的一致性，其允许将由于固有放射性的背景噪声检测为多重重合; 消除多重巧合; 并且使用比宽能窗口窄的能量窗口，以将符合事件限制在仅来自正电子核素的光峰中的重合事件。

10. 发明申请

US20140061483A1 COINCIDENCE DETERMINATION METHOD AND APPARATUS OF PET DEVICE 有权
标题翻译： PET装置的确定方法和装置
公开(公告)号：US20140061483A1
公开(公告)日：2014-03-06
申请号：US13846443
申请日：2013-03-18
申请人： NATIONAL INSTITUTE OF RADIOLOGICAL SCIENCES
发明人： Eiji YOSHIDA , Taiga YAMAYA
IPC分类号： G01T1/164
CPC分类号： G01T1/164 , G01T1/1647 , G01T1/2985
摘要： In a coincidence determination of a PET device, the PET device uses a scintillator of radioactive isotope containing background noise due to intrinsic radioactivity as a radiation detector. The PET device counts a pair of annihilation radiations that is assumed to occur from a same nuclide. The annihilation radiations are detected within a predetermined coincidence time window by a plurality of radiation detectors. The method includes determining a coincidence with a wide energy window that allows detecting the background noise due to intrinsic radioactivity as multiple coincidences; removing the multiple coincidences; and using an energy window narrower than the wide energy window to limit a coincidence event to a coincidence event in a photopeak from a positron nuclide only.
摘要翻译：在PET装置的重合判定中，PET装置使用由于内在放射性而含有背景噪声的放射性同位素的闪烁体作为放射线检测器。 PET装置计算出假定从同一个核素发生的一对湮灭辐射。通过多个辐射检测器在预定的重合时间窗内检测湮灭辐射。该方法包括确定与宽能量窗口的一致性，其允许将由于固有放射性的背景噪声检测为多重重合; 消除多重巧合; 并且使用比宽能窗口窄的能量窗口，以将符合事件限制在仅来自正电子核素的光峰中的重合事件。

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