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1. 发明授权

US09073821B2 Hydroxamic acid derivative 有权
标题翻译：羟肟酸衍生物
公开(公告)号：US09073821B2
公开(公告)日：2015-07-07
申请号：US13642320
申请日：2011-04-20
申请人： Hajime Takashima , Risa Tsuruta , Tetsuya Yabuuchi , Yusuke Oka , Hiroki Urabe , Yoichiro Suga , Masato Takahashi , Fumito Uneuchi , Hironori Kotsubo , Muneo Shoji , Yasuko Kawaguchi
发明人： Hajime Takashima , Risa Tsuruta , Tetsuya Yabuuchi , Yusuke Oka , Hiroki Urabe , Yoichiro Suga , Masato Takahashi , Fumito Uneuchi , Hironori Kotsubo , Muneo Shoji , Yasuko Kawaguchi
IPC分类号： C07C259/06 , C07C323/62 , C07D305/06 , C07D307/14 , C07D317/30 , C07D319/18 , C07D295/08 , C07D285/12 , C07D271/12 , C07D265/30 , C07D263/14 , C07D261/08 , C07D241/04 , C07C271/22 , C07C271/28 , C07C311/08 , C07C317/28 , C07C317/44 , C07C323/41 , C07D205/12 , C07D207/12 , C07D207/27 , C07D207/327 , C07D209/12 , C07D209/14 , C07D209/44 , C07D209/52 , C07D211/18 , C07D211/38 , C07D211/46 , C07D211/56 , C07D211/70 , C07D213/38 , C07D213/40 , C07D213/54 , C07D213/61 , C07D213/64 , C07D213/65 , C07D213/70 , C07D213/74 , C07D213/81 , C07D215/14 , C07D217/12 , C07D231/56 , C07D257/04 , C07D263/32 , C07D263/56 , C07D265/38 , C07D267/10 , C07D277/20 , C07D277/30 , C07D277/62 , C07D277/66 , C07D295/12 , C07D295/14 , C07D295/16 , C07D305/08 , C07D307/18 , C07D307/52 , C07D307/54 , C07D307/78 , C07D307/82 , C07D307/87 , C07D309/04 , C07D309/14 , C07D317/60 , C07D319/20 , C07D333/24 , C07D405/06 , C07D413/06 , C07D471/04 , C07D471/10 , C07D487/08 , C07D491/20 , C07D498/08 , C07F9/09 , C07D239/26 , C07D235/04 , C07D233/61 , C07D231/12 , C07D217/04 , C07D211/14 , C07D209/08 , C07D207/10 , C07D205/04
CPC分类号： C07C233/83 , C07C235/84 , C07C237/36 , C07C259/06 , C07C271/22 , C07C271/28 , C07C309/30 , C07C311/08 , C07C317/28 , C07C317/44 , C07C323/41 , C07C323/62 , C07C2601/02 , C07C2601/04 , C07C2601/08 , C07C2601/14 , C07C2601/16 , C07C2601/18 , C07C2602/08 , C07D205/04 , C07D205/12 , C07D207/10 , C07D207/12 , C07D207/27 , C07D207/327 , C07D209/08 , C07D209/12 , C07D209/14 , C07D209/44 , C07D209/52 , C07D211/14 , C07D211/18 , C07D211/38 , C07D211/46 , C07D211/56 , C07D211/70 , C07D213/38 , C07D213/40 , C07D213/54 , C07D213/61 , C07D213/64 , C07D213/65 , C07D213/70 , C07D213/74 , C07D213/81 , C07D215/14 , C07D217/04 , C07D217/12 , C07D231/12 , C07D231/56 , C07D233/61 , C07D235/04 , C07D257/04 , C07D261/08 , C07D263/14 , C07D263/32 , C07D263/56 , C07D265/30 , C07D265/36 , C07D265/38 , C07D267/10 , C07D271/12 , C07D277/20 , C07D277/30 , C07D277/62 , C07D277/66 , C07D285/12 , C07D295/08 , C07D295/12 , C07D295/14 , C07D295/16 , C07D305/06 , C07D305/08 , C07D307/14 , C07D307/18 , C07D307/52 , C07D307/54 , C07D307/78 , C07D307/81 , C07D307/82 , C07D307/87 , C07D309/04 , C07D309/14 , C07D317/30 , C07D317/60 , C07D319/18 , C07D319/20 , C07D333/24 , C07D405/06 , C07D413/06 , C07D471/04 , C07D471/10 , C07D487/08 , C07D491/20 , C07D498/04 , C07D498/08 , C07F9/091
摘要： Provided is a novel compound which is useful as a pharmaceutical composition by inhibiting an LpxC activity, thereby exhibiting potent antimicrobial activity against gram-negative bacteria including Pseudomonas aeruginosa and its drug resistant bacteria. Provided is a hydroxamic acid derivative represented by the following general formula [1] or a pharmaceutically acceptable salt thereof:
摘要翻译：提供了通过抑制LpxC活性可用作药物组合物的新型化合物，从而对包括绿脓假单胞菌及其耐药细菌在内的革兰氏阴性细菌表现出有效的抗微生物活性。提供由以下通式[1]表示的异羟肟酸衍生物或其药学上可接受的盐：

2. 发明申请

US20130072677A1 NOVEL HYDROXAMIC ACID DERIVATIVE 有权
公开(公告)号：US20130072677A1
公开(公告)日：2013-03-21
申请号：US13642320
申请日：2011-04-20
申请人： Hajime Takashima , Risa Tsuruta , Tetsuya Yabuuchi , Yusuke Oka , Hiroki Urabe , Yoichiro Suga , Masato Takahashi , Fumito Uneuchi , Hironori Kotsubo , Muneo Shoji , Yasuko Kawaguchi
发明人： Hajime Takashima , Risa Tsuruta , Tetsuya Yabuuchi , Yusuke Oka , Hiroki Urabe , Yoichiro Suga , Masato Takahashi , Fumito Uneuchi , Hironori Kotsubo , Muneo Shoji , Yasuko Kawaguchi
IPC分类号： C07C259/06 , C07D267/10 , C07D261/08 , C07D205/04 , C07D211/46 , C07D498/04 , C07D305/08 , C07D491/107 , C07D307/52 , C07D295/155 , C07D413/06 , C07D265/36 , C07D295/088 , C07D305/06
CPC分类号： C07C233/83 , C07C235/84 , C07C237/36 , C07C259/06 , C07C271/22 , C07C271/28 , C07C309/30 , C07C311/08 , C07C317/28 , C07C317/44 , C07C323/41 , C07C323/62 , C07C2601/02 , C07C2601/04 , C07C2601/08 , C07C2601/14 , C07C2601/16 , C07C2601/18 , C07C2602/08 , C07D205/04 , C07D205/12 , C07D207/10 , C07D207/12 , C07D207/27 , C07D207/327 , C07D209/08 , C07D209/12 , C07D209/14 , C07D209/44 , C07D209/52 , C07D211/14 , C07D211/18 , C07D211/38 , C07D211/46 , C07D211/56 , C07D211/70 , C07D213/38 , C07D213/40 , C07D213/54 , C07D213/61 , C07D213/64 , C07D213/65 , C07D213/70 , C07D213/74 , C07D213/81 , C07D215/14 , C07D217/04 , C07D217/12 , C07D231/12 , C07D231/56 , C07D233/61 , C07D235/04 , C07D257/04 , C07D261/08 , C07D263/14 , C07D263/32 , C07D263/56 , C07D265/30 , C07D265/36 , C07D265/38 , C07D267/10 , C07D271/12 , C07D277/20 , C07D277/30 , C07D277/62 , C07D277/66 , C07D285/12 , C07D295/08 , C07D295/12 , C07D295/14 , C07D295/16 , C07D305/06 , C07D305/08 , C07D307/14 , C07D307/18 , C07D307/52 , C07D307/54 , C07D307/78 , C07D307/81 , C07D307/82 , C07D307/87 , C07D309/04 , C07D309/14 , C07D317/30 , C07D317/60 , C07D319/18 , C07D319/20 , C07D333/24 , C07D405/06 , C07D413/06 , C07D471/04 , C07D471/10 , C07D487/08 , C07D491/20 , C07D498/04 , C07D498/08 , C07F9/091
摘要： Provided is a novel compound which is useful as a pharmaceutical composition by inhibiting an LpxC activity, thereby exhibiting potent antimicrobial activity against gram-negative bacteria including Pseudomonas aeruginosa and its drug resistant bacteria. Provided is a hydroxamic acid derivative represented by the following general formula [1] or a pharmaceutically acceptable salt thereof:

3. 发明授权

US5874926A Matching circuit and antenna apparatus 失效
标题翻译：匹配电路和天线装置
公开(公告)号：US5874926A
公开(公告)日：1999-02-23
申请号：US815277
申请日：1997-03-10
申请人： Teruhisa Tsuru , Harufumi Mandai , Toshifumi Oida , Yoichiro Suga
发明人： Teruhisa Tsuru , Harufumi Mandai , Toshifumi Oida , Yoichiro Suga
IPC分类号： H01Q1/36 , H01Q1/38 , H01Q1/50
CPC分类号： H04B1/18 , H01Q1/362 , H01Q1/38 , H03H7/40
摘要： A matching circuit and an antenna apparatus which, though small-sized, can be used in a radio apparatus which transmits and receives radio waves having a wide range of frequencies. A matching circuit includes an inductance element formed of a chip inductor connected in series with an antenna body, a first capacitance element formed of a trimmer capacitor, and a second capacitance element formed of a chip capacitor, which capacitance elements are connected between respective ends of the inductance element and a ground terminal, and thus in parallel to the antenna body. One end of the inductance element is connected to the power supply terminal of the antenna body, and the other end is connected to a power source for applying a voltage to the antenna body. The first capacitance element is connected between a ground and the connection point of the power supply terminal of the antenna body and the inductance element. The second capacitance element is connected between a ground and the connection point of the inductance element and the power source.
摘要翻译：尽管体积小的匹配电路和天线装置可以用于发送和接收具有宽频率范围的无线电波的无线电装置中。匹配电路包括由与天线体串联连接的芯片电感器形成的电感元件，由微调电容器形成的第一电容元件和由片状电容器形成的第二电容元件，所述电容元件连接在电感元件和接地端子，因此平行于天线体。电感元件的一端连接到天线体的电源端子，另一端连接到用于向天线体施加电压的电源。第一电容元件连接在地与天线体的电源端子与电感元件的连接点之间。第二电容元件连接在接地和电感元件与电源的连接点之间。

4. 发明申请

US20050222423A1 Carboxylic acid derivative 审中-公开
标题翻译：羧酸衍生物
公开(公告)号：US20050222423A1
公开(公告)日：2005-10-06
申请号：US10500135
申请日：2002-12-26
申请人： Shuji Saito , Yoichiro Suga , Masakazu Sato , Masabumi Shibuya
发明人： Shuji Saito , Yoichiro Suga , Masakazu Sato , Masabumi Shibuya
IPC分类号： A61K31/198 , A61K31/343 , A61K31/352 , A61K31/381 , A61K31/40 , A61K31/403 , A61K31/42 , A61K31/421 , A61K31/4245 , A61K31/426 , A61K31/428 , A61K31/4453 , A61K31/5375 , A61P3/00 , A61P9/00 , A61P27/02 , A61P29/00 , A61P35/00 , A61P43/00 , C07C235/38 , C07C255/60 , C07C311/46 , C07C317/40 , C07C323/41 , C07D209/76 , C07D261/14 , C07D263/32 , C07D271/10 , C07D277/28 , C07D277/38 , C07D277/42 , C07D277/62 , C07D295/26 , C07D307/91 , C07D311/14 , C07D333/34 , C07D413/02
CPC分类号： C07D271/10 , A61K31/198 , A61K31/343 , A61K31/352 , A61K31/381 , A61K31/40 , A61K31/403 , A61K31/42 , A61K31/421 , A61K31/4245 , A61K31/426 , A61K31/428 , A61K31/4453 , A61K31/5375 , C07C235/38 , C07C255/60 , C07C311/46 , C07C317/40 , C07C323/41 , C07D209/76 , C07D261/14 , C07D263/32 , C07D277/28 , C07D277/38 , C07D277/42 , C07D277/62 , C07D295/26 , C07D307/91 , C07D311/14 , C07D333/34
摘要： The following compounds useful as VEGF receptor antagonists and having excellent physical properties are provided. A carboxylic acid derivative represented by formula: wherein ring A represents a benzene ring, a naphthalene ring, or the like; W represents a C1-5 alkylene group; Z represents a single bond or a phenylene group; R1 and R2 are the same or different and each represents a hydrogen atom, a halogen atom, a C1-5 alkyl group or a C1-10 alkoxy group; R3 represents a hydrogen atom, a halogen atom, a C1-12 alkyl group, a C2-5 alkynyl group, a trifluoromethyl group, an acetylenyl group, a cyano group, a nitro group, —CH2—R6, —Y—R11, or the like; R4 represents a group represented by formula: and R5 represents a hydrogen atom or a C1-5 alkyl group, or a pharmaceutical acceptable salt of the derivative.
摘要翻译：提供了可用作VEGF受体拮抗剂并具有优异物理性质的以下化合物。由下式表示的羧酸衍生物：其中环A表示苯环，萘环等; W表示C 1-5亚烷基; Z表示单键或亚苯基; R 1和R 2相同或不同，各自表示氢原子，卤素原子，C 1-5烷基或 C 1-10烷氧基; R 3表示氢原子，卤素原子，C 1-12烷基，C 2-5炔基，三氟甲基基团，乙炔基，氰基，硝基，-CH 2 2 -OR 6，-YR 11等; R 4表示由式表示的基团：R 5表示氢原子或C 1-5烷基，或药学上可接受的衍生物的盐。

5. 发明授权

US5539647A Vehicle navigation system using GPS including correction of coefficients for velocity sensor 失效
标题翻译：使用GPS的车载导航系统，包括校正速度传感器的系数
公开(公告)号：US5539647A
公开(公告)日：1996-07-23
申请号：US530586
申请日：1995-09-19
申请人： Akihito Shibata , Hiroaki Tsuji , Yoichiro Suga
发明人： Akihito Shibata , Hiroaki Tsuji , Yoichiro Suga
IPC分类号： G01C21/28 , G06F165/00
CPC分类号： G01C21/28
摘要： A vehicle navigation system automatically corrects the coefficient of its velocity sensor with high precision. This system obtains a distance between two positions measured by a GPS and a linear travel distance calculated on the basis of the signals outputted by the velocity sensor during a period between the measurement of the two positions. Then, the system corrects the velocity sensor coefficient so that the linear travel distance becomes equal to the distance between the two positions.
摘要翻译：车辆导航系统以高精度自动校正其速度传感器的系数。该系统在两个位置的测量期间获得由GPS测量的两个位置之间的距离和基于由速度传感器输出的信号计算的线性行进距离。然后，系统校正速度传感器系数，使得线性行进距离变得等于两个位置之间的距离。

6. 发明授权

US5483457A Vehicle navigation system using GPS including correction of coefficients for velocity sensor 失效
公开(公告)号：US5483457A
公开(公告)日：1996-01-09
申请号：US963751
申请日：1992-10-20
申请人： Akihito Shibata , Hiroaki Tsuji , Yoichiro Suga
发明人： Akihito Shibata , Hiroaki Tsuji , Yoichiro Suga
IPC分类号： G01C21/28 , G06F165/00
CPC分类号： G01C21/28
摘要： A vehicle navigation system automatically corrects the coefficient of its velocity sensor with high precision. This system obtains a distance between two positions measured by a GPS and a linear travel distance calculated on the basis of the signals outputted by the velocity sensor during a period between the measurement of the two positions. Then, the system corrects the velocity sensor coefficient so that the linear travel distance becomes equal to the distance between the two positions.

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