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1. 发明授权

US11426603B2 Radiation irradiation planning apparatus, clinical decision support apparatus and program 有权
公开(公告)号：US11426603B2
公开(公告)日：2022-08-30
申请号：US16467504
申请日：2016-12-19
申请人： HITACHI, LTD. , NATIONAL UNIVERSITY CORPORATION HOKKAIDO UNIVERSITY
发明人： Keiji Kobashi , Masahiro Mizuta , Hiroyuki Date , Hiroki Shirato , Shinichi Shimizu , Kikuo Umegaki , Shusuke Hirayama , Yusuke Fujii , Toru Umekawa , Rintarou Fujimoto
IPC分类号： A61N5/10
摘要： A treatment planning apparatus 501 or a clinical decision support apparatus 701 calculates a dose distribution, calculates the damage to a normal tissue for a plurality of number of times of radiation irradiation based on the calculated dose distribution, and displays at least one or more calculated damages to the normal tissues on display apparatuses 603 and 703 or outputs the same to an outside of the apparatuses 501 and 701. Accordingly, since effects can be calculated for a plurality of number of times of irradiation, the optimum number of time of irradiation can be presented, and an operator and a doctor can be presented with a suitable decision material of a radiation irradiation planning.

2. 发明授权

US11282244B2 Moving body tracking apparatus, radiation therapy system including the same, program, and moving body tracking method 有权
公开(公告)号：US11282244B2
公开(公告)日：2022-03-22
申请号：US16783206
申请日：2020-02-06
申请人： Hitachi, Ltd. , NATIONAL UNIVERSITY CORPORATION HOKKAIDO UNIVERSITY
发明人： Toru Umekawa , Koichi Miyazaki , Takaaki Fujii , Shinichi Shimizu , Seishin Takao , Kikuo Umegaki , Naoki Miyamoto , Norio Katoh
IPC分类号： G06K9/00 , G06T11/00 , G06T7/70 , G06T7/00 , G06T7/20
摘要： Provided are a moving body tracking apparatus that contributes to shortening treatment time and a radiation therapy system including the moving body tracking apparatus, a program, and a moving body tracking method. The moving body tracking apparatus includes a fluoroscopic apparatus that acquires fluoroscopic images including the target 2 from at least two directions, and the moving body tracking control apparatus 30A that obtains a position of the target 2 from the fluoroscopic images acquired by the fluoroscopic apparatus. The moving body tracking control apparatus 30A creates a simulated fluoroscopic image from the CT image including the target 2, creates a two-dimensional region including the target 2 from the simulated fluoroscopic image as a template, matches each of at least two fluoroscopic images with the template, and obtains a three-dimensional position of the target 2 from a plurality of matching results.

3. 发明授权

US10751552B2 Tumor tracking apparatus and irradiation system 有权
公开(公告)号：US10751552B2
公开(公告)日：2020-08-25
申请号：US16088534
申请日：2017-03-30
申请人： HITACHI, LTD. , NATIONAL UNIVERSITY CORPORATION HOKKAIDO UNIVERSITY
发明人： Takahiro Yamada , Toru Umekawa , Yusuke Fujii , Naoki Miyamoto , Kikuo Umegaki
IPC分类号： A61N5/10 , A61B6/12 , A61B6/02 , A61B6/00
摘要： A tumor tracking control device (41) performs windowing process on a captured image A (61) and a captured image B (62), measures a position of a marker (29) using the captured image A (61) and the captured image B (62) after performing the windowing process, and generates a signal capable of controlling irradiation with radiation based on the position of the marker (29). Accordingly, it is possible to provide a tumor tracking apparatus and an irradiation system which are capable of tracking an object to be tracked without erroneous detection, even in a case where a structure similar to the object to be tracked is in the vicinity of the object to be tracked, in tumor tracking.

4. 发明授权

US11439848B2 Radiation irradiating system and moving object tracking system 有权
公开(公告)号：US11439848B2
公开(公告)日：2022-09-13
申请号：US16302106
申请日：2017-05-11
申请人： HITACHI, LTD. , NATIONAL UNIVERSITY CORPORATION HOKKAIDO UNIVERSITY
发明人： Yusuke Fujii , Naoki Miyamoto , Kikuo Umegaki , Shinichi Shimizu , Toru Umekawa , Takahiro Yamada
IPC分类号： A61N5/10 , A61B6/02 , A61B90/00
摘要： A template matching is performed on two fluoroscopic images by using a template image prepared in advance and a position corresponding to a high matching score is listed as a candidate for the position of a marker 29. From two lists of the candidates of the position of the marker 29, the lengths of common vertical lines for all combinations are calculated. Then, the position of the marker 29 is detected based on the matching score and the common vertical line. Then, based on the detected position of the marker 29, an amount of a proton beam to be irradiated to a target is controlled. Therefore, a tracking target can be accurately detected even when the conditions for X-ray fluoroscopy is severe, e.g., a thick object.

5. 发明授权

US09757590B2 Charged particle beam system 有权
公开(公告)号：US09757590B2
公开(公告)日：2017-09-12
申请号：US14524495
申请日：2014-10-27
申请人： HITACHI, LTD. , NATIONAL UNIVERSITY CORPORATION HOKKAIDO UNIVERSITY
发明人： Kazuo Hiramoto , Masumi Umezawa , Shinichiro Fujitaka , Hiroki Shirato , Shinichi Shimizu , Kikuo Umegaki
IPC分类号： A61N5/10 , A61N5/00 , G21K5/04 , G21K1/08
CPC分类号： A61N5/1048 , A61N5/1043 , A61N5/1081 , A61N2005/1074 , A61N2005/1087 , G21K1/08 , G21K5/04
摘要： First ions and second ions that are heavier than first ions are generated in an ion source. One kind of ions of the first ions and second ions is injected into an accelerator by action of a switching magnet and accelerated in the accelerator. An ion beam including the one kind of ions is extracted from the accelerator to a beam transport system and a tumor volume of a patient is irradiated with the ion beam from an irradiation nozzle. In the irradiation of the ion beam, a tumor volume depth and the largest underwater range of each ion species are compared, and an ion species in which the tumor volume depth becomes the longest underwater range or lower is injected into the accelerator, and accelerated by the accelerator. The tumor volume is irradiated with the ion species.

6. 发明申请

US20140330066A1 SYSTEM FOR IRRADIATING CHARGED PARTICLES AND METHOD FOR IRRADIATING CHARGED PARTICLES 有权
标题翻译：用于辐射充电颗粒的系统和用于辐射充电颗粒的方法
公开(公告)号：US20140330066A1
公开(公告)日：2014-11-06
申请号：US14361416
申请日：2012-11-14
申请人： HITACHI, LTD. , NATIONAL UNIVERSITY CORPORATION HOKKAIDO UNIVERSITY
发明人： Yusuke Fujii , Toru Umekawa , Masumi Umezawa , Hiroki Shirato , Kikuo Umegaki , Naoki Miyamoto , Taeko Matsuura
IPC分类号： A61N5/10
CPC分类号： A61N5/1068 , A61N5/1077 , A61N2005/1074 , A61N2005/1087
摘要： A charged particle irradiation system is capable of shortening the irradiation time and the treatment time by performing efficient irradiation even when irregular variation occurs in the irradiation object during the gating irradiation. The extraction of the beam is stopped upon reception of a regular extraction permission end signal which is outputted based on a regular movement signal. An extractable state maintaining function operates upon the reception of the extraction permission end signal. When a preset standby time elapses without receiving an extraction permission start signal again during the standby time, the extractable state maintaining function finishes its operation and a charged particle beam generator decelerates the beam. Also, the extraction of the beam is stopped due to reception of an irregular extraction permission end signal during the irradiation. When the extraction permission start signal is received again during the standby time, the extraction of the beam is restarted.
摘要翻译：带电粒子照射系统即使在门控照射期间在照射物体中发生不规则变化，也能够通过高效照射缩短照射时间和处理时间。在接收到基于规则移动信号输出的常规提取许可结束信号时，停止提取光束。可提取状态维持功能在接收到提取许可结束信号时进行操作。当在待机时间期间经过预设待机时间而不再接收到提取许可开始信号时，可提取状态维持功能完成其操作，并且带电粒子束发生器使光束减速。此外，由于在照射期间接收到不规则的提取许可结束信号，停止提取光束。当在待机时间期间再次接收到提取许可开始信号时，重新开始提取光束。

7. 发明授权

US09899112B2 Particle beam therapy system, ridge filter, and method of making ridge filter 有权
公开(公告)号：US09899112B2
公开(公告)日：2018-02-20
申请号：US15437826
申请日：2017-02-21
申请人： Hitachi, Ltd. , NATIONAL UNIVERSITY CORPORATION HOKKAIDO UNIVERSITY
发明人： Taisuke Takayanagi , Shinichiro Fujitaka , Chihiro Nakashima , Tomoki Murata , Taeko Matsuura , Naoki Miyamoto , Kikuo Umegaki , Yuichi Hirata
IPC分类号： G21K1/10 , G21K5/04 , H05H13/04
CPC分类号： G21K1/10 , A61N5/1077 , A61N2005/1087 , A61N2005/1095 , G21K5/04 , H05H7/12 , H05H13/04 , H05H2007/004
摘要： A structure configuring a ridge filter has line symmetry about a line vertical to a depth direction passing the center of the structure. A small structure obtained in such a way that the structure is divided by this line has a bilaterally asymmetric shape about a center line in an iterative direction, and has a point symmetric shape about an intersection between the center line in the iterative direction and the center line in the depth direction. Thicknesses in the iterative direction of an uppermost stream surface and a lowermost stream surface in the depth direction are equal to each other. The structure is configured so that a thick portion in the iterative direction of the uppermost stream surface and the lowermost stream surface is not present in the depth direction.

8. 发明授权

US09061144B2 System for irradiating charged particles and method for irradiating charged particles 有权
标题翻译：用于照射带电粒子的系统和照射带电粒子的方法
公开(公告)号：US09061144B2
公开(公告)日：2015-06-23
申请号：US14361416
申请日：2012-11-14
申请人： HITACHI, LTD. , NATIONAL UNIVERSITY CORPORATION HOKKAIDO UNIVERSITY
发明人： Yusuke Fujii , Toru Umekawa , Masumi Umezawa , Hiroki Shirato , Kikuo Umegaki , Naoki Miyamoto , Taeko Matsuura
IPC分类号： G21K5/04 , A61N5/10
CPC分类号： A61N5/1068 , A61N5/1077 , A61N2005/1074 , A61N2005/1087
摘要： A charged particle irradiation system is capable of shortening the irradiation time and the treatment time by performing efficient irradiation even when irregular variation occurs in the irradiation object during the gating irradiation. The extraction of the beam is stopped upon reception of a regular extraction permission end signal which is outputted based on a regular movement signal. An extractable state maintaining function operates upon the reception of the extraction permission end signal. When a preset standby time elapses without receiving an extraction permission start signal again during the standby time, the extractable state maintaining function finishes its operation and a charged particle beam generator decelerates the beam. Also, the extraction of the beam is stopped due to reception of an irregular extraction permission end signal during the irradiation. When the extraction permission start signal is received again during the standby time, the extraction of the beam is restarted.
摘要翻译：带电粒子照射系统即使在门控照射期间在照射物体中发生不规则变化，也能够通过高效照射缩短照射时间和处理时间。在接收到基于规则移动信号输出的常规提取许可结束信号时，停止提取光束。可提取状态维持功能在接收到提取许可结束信号时进行操作。当在待机时间期间经过预设待机时间而不再接收到提取许可开始信号时，可提取状态维持功能完成其操作，并且带电粒子束发生器使光束减速。此外，由于在照射期间接收到不规则的提取许可结束信号，停止提取光束。当在待机时间期间再次接收到提取许可开始信号时，重新开始提取光束。

9. 发明申请

US20200009404A1 RADIATION THERAPY APPARATUS 审中-公开
公开(公告)号：US20200009404A1
公开(公告)日：2020-01-09
申请号：US16493955
申请日：2018-03-12
申请人： National University Corporation Hokkaido University
发明人： Takaaki Fujii , Seishin Takao , Naoki Miyamoto , Taeko Matsuura , Kikuo Umegaki
IPC分类号： A61N5/10 , A61B90/00
摘要： Through the present invention, three-dimensional coordinates of a tracking object moving in an irradiation object can be calculated from fluoroscopic X-ray images captured and acquired from various angles in a single fluoroscopic X-ray device mounted to a radiation therapy apparatus. The three-dimensional coordinates of the tracking object are calculated on a straight tracking object presence line connecting an X-ray generating device for fluoroscopy and the position in an X-ray plane detector of the tracking object on the fluoroscopic X-ray image acquired by the X-ray generating device for fluoroscopy and the X-ray plane detector, and using line segment information included in a movement region of the tracking object set in advance (S104).

10. 发明申请

US20150087881A1 RADIOTHERAPY CONTROL APPARATUS AND RADIOTHERAPY CONTROL PROGRAM 有权
标题翻译：放射治疗控制装置和放射治疗方案
公开(公告)号：US20150087881A1
公开(公告)日：2015-03-26
申请号：US14386166
申请日：2013-02-26
申请人： NATIONAL UNIVERSITY CORPORATION HOKKAIDO UNIVERSITY
发明人： Naoki Miyamoto , Shinichi Shimizu , Taeko Matsuura , Chie Toramatsu , Seishin Takao , Hideaki Nihongi , Yuichi Hirata , Kikuo Umegaki
IPC分类号： A61N5/10 , A61B19/00 , A61B6/00
CPC分类号： A61N5/1039 , A61B6/022 , A61B6/487 , A61B6/5211 , A61B2090/3966 , A61N5/1037 , A61N5/1049 , A61N2005/1061 , A61N2005/1074
摘要： [Problem to be Solved]To provide a radiotherapy control apparatus and radiotherapy control program capable of calculating the current positions of markers implanted in a patient by means of a single fluoroscopic imaging device and reducing a radiation exposure dose inflicted on the patient by radiographic radiation used for fluoroscopic observation during radiotherapy.[Solution]The present invention includes a fluoroscopic image acquisition unit 41 adapted to acquire a fluoroscopic image of three or more markers from a single fluoroscopic imaging device 12, a projection line calculation unit 38 adapted to calculate equations of respective projection lines, an inter-marker distance acquisition unit 42 adapted to acquire each distance between each pair of the markers, a marker position calculation unit 43 adapted to calculate current positions of the respective markers, and a therapeutic radiation emission determination unit 44 adapted to determine whether to emit therapeutic radiation.
摘要翻译： [待解决的问题]提供一种放射治疗控制装置和放射线治疗控制程序，其能够通过单个透视成像装置计算植入患者体内的标记的当前位置，并且通过使用的放射线照射减少对患者施加的辐射照射剂量用于放射治疗期间的透视观察。 [解决方案]本发明包括一种荧光镜图像获取单元41，适用于从单个透视成像装置12获取三个或更多个标记的透视图像，投影线计算单元38，其适于计算各个投影线的等式，标记距离获取单元42，适于获取每对标记之间的每个距离，适于计算各个标记的当前位置的标记位置计算单元43，以及适于确定是否发射治疗辐射的治疗辐射发射确定单元44。

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