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1. 发明申请

US20130126719A1 Gas chromatography-mass spectrometry method and gas chromatography-mass spectrometry apparatus therefor having a capture and release device 有权
标题翻译：气相色谱 - 质谱法和气相色谱 - 质谱仪具有捕获和释放装置
公开(公告)号：US20130126719A1
公开(公告)日：2013-05-23
申请号：US13609290
申请日：2012-09-11
申请人： Hongliang Lu , Kai Lin , Jing Yu , Qun Chen
发明人： Hongliang Lu , Kai Lin , Jing Yu , Qun Chen
IPC分类号： H01J49/26
CPC分类号： G01N30/461 , G01N30/7206
摘要： A GC-MS method is provided with installing a sample injector; installing a heart-cutting unit; installing a first capillary column; connecting a switching valve to the heart-cutting unit; installing a capture and release device to the heart-cutting unit; connecting the capture and release device to the switching valve; connecting the switching valve to an MS; rotating the switching valve to either connect the first and second interconnecting columns, or connect the second capillary column and the second interconnecting column; injecting the sample gas into the first capillary column; by setting a time slot and carrier gas pressure of the heart-cutting unit, while causing fractions of simple compounds to be cut out and travel to the MS, causing fractions of complex compounds to be cut out; after the simple compounds finished in MS, causing complex compounds to be released from the capture and release device; and sending the compounds.
摘要翻译：提供GC-MS方法安装样品注射器; 安装一个心切单元; 安装第一个毛细管柱; 将切换阀连接到心脏切割单元; 将切割装置安装到心脏切割装置上; 将捕获和释放装置连接到切换阀; 将切换阀连接到MS; 旋转切换阀以连接第一和第二互连柱，或连接第二毛细管柱和第二互连柱; 将样品气体注入第一毛细管柱; 通过设置心切单元的时隙和载气压力，同时使单个化合物的馏分被切出并行进到MS，导致复合化合物的馏分被切出; 在MS中简单化合物完成后，导致复合化合物从捕获和释放装置中释放; 并发送化合物。

2. 发明授权

US09228984B2 Gas chromatography-mass spectrometry method and gas chromatography-mass spectrometry apparatus therefor having a capture and release device 有权
公开(公告)号：US09228984B2
公开(公告)日：2016-01-05
申请号：US13609290
申请日：2012-09-11
申请人： Hongliang Lu , Kai Lin , Jing Yu , Qun Chen
发明人： Hongliang Lu , Kai Lin , Jing Yu , Qun Chen
IPC分类号： H01J49/26 , G01N30/46 , G01N30/72
CPC分类号： G01N30/461 , G01N30/7206
摘要： A GC-MS method is provided with installing a sample injector; installing a heart-cutting unit; installing a first capillary column; connecting a switching valve to the heart-cutting unit; installing a capture and release device to the heart-cutting unit; connecting the capture and release device to the switching valve; connecting the switching valve to an MS; rotating the switching valve to either connect the first and second interconnecting columns, or connect the second capillary column and the second interconnecting column; injecting the sample gas into the first capillary column; by setting a time slot and carrier gas pressure of the heart-cutting unit, while causing fractions of simple compounds to be cut out and travel to the MS, causing fractions of complex compounds to be cut out; after the simple compounds finished in MS, causing complex compounds to be released from the capture and release device; and sending the compounds.

3. 发明申请

US20080044437A1 Encapsidation System for Production of Recombinant Virus-Like Particles 审中-公开
标题翻译：用于生产重组病毒样颗粒的封装系统
公开(公告)号：US20080044437A1
公开(公告)日：2008-02-21
申请号：US11661912
申请日：2005-09-01
申请人： Qun Chen
发明人： Qun Chen
IPC分类号： A61K39/12 , A61P37/00 , C12N15/86
CPC分类号： C12N7/00 , A61K39/12 , A61K39/145 , A61K39/21 , A61K39/215 , A61K2039/5258 , A61K2039/54 , A61K2039/545 , A61K2039/70 , C07K14/005 , C12N15/86 , C12N2740/16022 , C12N2740/16023 , C12N2740/16034 , C12N2740/16043 , C12N2760/16122 , C12N2760/16134 , C12N2770/20022 , C12N2770/20034
摘要： The present invention relates to methods and compositions for manufacturing virus-like particles (VLPs), suitable for use as immunogens and as research tools. The VLPs of the present invention provide a sale alternative to the use of pathogenic viruses for clinical and laboratory applications.
摘要翻译：本发明涉及适用于免疫原和研究工具的用于制造病毒样颗粒（VLPs）的方法和组合物。本发明的VLP提供了用于临床和实验室应用的病原性病毒的销售替代方案。

4. 发明申请

US20070190663A1 System and method for using polarized or hyperpolarized contrast agent to perform parallel magnetic resonance imaging of a sample 审中-公开
标题翻译：使用偏振或超极化造影剂进行样品的平行磁共振成像的系统和方法
公开(公告)号：US20070190663A1
公开(公告)日：2007-08-16
申请号：US11504570
申请日：2006-08-14
申请人： Ray Lee , Georgeann McGunness , Glyn Johnson , Qun Chen , Robert Grossman
发明人： Ray Lee , Georgeann McGunness , Glyn Johnson , Qun Chen , Robert Grossman
IPC分类号： G01N24/00 , A61B5/05
CPC分类号： G01R33/5601 , G01R33/3415 , G01R33/3635 , G01R33/3642 , G01R33/365 , G01R33/5611 , Y10T436/24
摘要： A system and method for performing parallel magnetic resonance imaging (“MRI”) with a polarizable or hyperpolarizable contrast agent are provided. The contrast agent may be provided in the form of a gas, a liquid, or a solid. The system may include a phased-array rigid coil with, e.g., a 24-channel phased-array for a receiver and a 2-channel large loop for a transmitter. The phased-array rigid coil can be connected to a low impedance preamplifier for decoupling the strong coupling between two adjacent coils in the phased-array rigid coil. The system and method may be used for enhancing the signal-to-noise ratio, and/or reducing the scan acquisition time of acquired images in a parallel MRI scan of a patient who is breathing a hyperpolarized gas.
摘要翻译：提供了一种用可极化或超极化造影剂进行并行磁共振成像（“MRI”）的系统和方法。造影剂可以以气体，液体或固体的形式提供。该系统可以包括具有例如用于接收器的24通道相控阵列和用于发射器的2通道大环路的相控阵刚体线圈。相控阵刚体线圈可以连接到低阻抗前置放大器，用于去耦相控阵刚体线圈中两个相邻线圈之间的强耦合。该系统和方法可以用于增强信噪比，和/或减少在呼吸超极化气体的患者的并行MRI扫描中获取的图像的扫描获取时间。

5. 发明授权

US06375869B1 AB5-type rare earth transition intermetallic compounds for the negative electrodes of rechargeable batteries 有权
标题翻译：用于可充电电池负极的AB5型稀土过渡金属间化合物
公开(公告)号：US06375869B1
公开(公告)日：2002-04-23
申请号：US09492869
申请日：2000-01-27
申请人： Tsong P. Perng , Bao-Min Ma , James Landi , Qun Chen
发明人： Tsong P. Perng , Bao-Min Ma , James Landi , Qun Chen
IPC分类号： H01B108
CPC分类号： H01M4/46 , C01B3/0057 , C22C28/00 , H01M4/383 , Y02E60/327
摘要： Manganese-free rare earth-transition metal AB5-type hydrogen-absorbing alloys having favorable high rate discharge characteristics, suitable for use in rechargeable batteries for electrical vehicles or hybrid electrical vehicles, include compositions of the general formula: R(CouAlvMwNi1−u−v−w)z, where R is at least one element selected from rare earth elements and yttrium (Y), M is at least one refractory metal selected from Groups IVB, VB, and VIB of the periodic table, the value of u is from 0 to about 0.25, v is from 0 to about 0.10, w is from 0 to about 0.05, and z, the ratio of R(CouAlvMwNi1−u−v−w)/R, is from about 4.70 to about 5.50. The unit cell volume is from about 87 to about 88.5 A3 at 25° C., the plateau pressure is from about 3 to about 10 apsi at 25° C., and the composition is essentially free of manganese.
摘要翻译：适用于电动车辆或混合电动车辆用充电电池的具有良好高倍率放电特性的无锰稀土过渡金属AB5型吸氢合金包括以下通式的组合物：R（CouAlvMwNi1-uvw）z 其中R是选自稀土元素和钇（Y）中的至少一种元素，M是选自元素周期表IVB，VB和VIB族的至少一种难熔金属，u的值为0至约0.25 ，v为0至约0.10，w为0至约0.05，而z（CouAlvMwNi1-uvw）/ R的比例为约4.70至约5.50。在25℃，单位电池体积为约87至约88.5A A3，平台压力在25℃为约3至约10psi，组合物基本上不含锰。

6. 发明授权

US06332933B1 Iron-rare earth-boron-refractory metal magnetic nanocomposites 失效
$Iron-rare earth-boron-refractory metal magnetic nanocomposites$
标题翻译：铁 - 稀土 - 硼 - 难熔金属磁性纳米复合材料
公开(公告)号：US06332933B1
公开(公告)日：2001-12-25
申请号：US09001727
申请日：1997-12-31
申请人： Bao-Min Ma , Charles O. Bounds , Wen Cheng Chang , Qun Chen
发明人： Bao-Min Ma , Charles O. Bounds , Wen Cheng Chang , Qun Chen
IPC分类号： H01F1057
CPC分类号： B82Y25/00 , C22C38/00 , H01F1/0579
摘要： Magnetic nanocomposite materials including iron, rare earth elements, boron, refractory metal and, optionally, cobalt are disclosed. Neodymium and lanthanum are preferred rare earth elements. The amounts of Nd, La, B and refractory metal are controlled in order to produce both hard and soft magnetic phases, as well as a refractory metal boride precipitated phase. The refractory metal boride precipitates serve as grain refiners and substantially improve the magnetic properties of the nanocomposite materials. The materials are particularly suitable for making bonded magnets.
摘要翻译：公开了包括铁，稀土元素，硼，难熔金属和任选的钴的磁性纳米复合材料。钕和镧是优选的稀土元素。控制Nd，La，B和难熔金属的量以产生硬磁相和软磁相以及难熔金属硼化物沉淀相。难熔金属硼化物沉淀物用作晶粒细化剂并且显着改善纳米复合材料的磁性能。这些材料特别适用于制造粘结磁体。

7. 发明授权

US09785894B2 Simulation of supply chain plans using web service 有权
公开(公告)号：US09785894B2
公开(公告)日：2017-10-10
申请号：US12751535
申请日：2010-03-31
申请人： Manoj Abraham , Qun Chen
发明人： Manoj Abraham , Qun Chen
IPC分类号： G06Q10/06
CPC分类号： G06Q10/06 , G06Q10/063
摘要： A new computer-readable medium, computer-implemented method, and system is provided which can allow a user to make changes to the planning data, generate a new plan, generate a new solution based on the generated plan, or perform an alternative scenario analysis on the generated plan. In one embodiment, a new model for representing planning data, identified as a “base-plus-delta” model is provided. In another embodiment, a new web service implementation for a planning engine is provided. In another embodiment, a new technique for copying plans to perform an alternative scenario analysis on the copied plan is provided. In another embodiment, an automatic propagation of user changes from a database directly to an in-memory object is provided. In certain embodiments of the invention, two or more of the described features can be combined to provide an interactive supply chain planning system.

8. 发明授权

US06933377B2 Compositions comprising multiple immunodeficiency virus subunits for inducing an immune response 失效
标题翻译：包含用于诱导免疫应答的多种免疫缺陷病毒亚基的组合物
公开(公告)号：US06933377B2
公开(公告)日：2005-08-23
申请号：US10207346
申请日：2002-07-29
申请人： Qun Chen
发明人： Qun Chen
IPC分类号： A61K39/21 , C07K14/16 , C07H21/04
CPC分类号： C07K14/005 , A61K39/12 , A61K39/21 , A61K2039/5258 , A61K2039/53 , A61K2039/545 , C12N2740/16034 , C12N2740/16043 , C12N2740/16122 , C12N2740/16134 , C12N2740/16234 , C12N2740/16322 , C12N2740/16334
摘要： The present invention relates to prophylactic and therapeutic acquired immunodeficiency syndrome vaccines. In particular, the present invention provides methods and compositions utilizing recombinant HIV-1, HIV-2 and/or SIV genes or gene products in safe vaccination approaches.
摘要翻译：本发明涉及预防和治疗性获得性免疫缺陷综合征疫苗。特别地，本发明提供了在安全接种方法中利用重组HIV-1，HIV-2和/或SIV基因或基因产物的方法和组合物。

9. 发明授权

US06198958B1 Method and apparatus for monitoring a magnetic resonance image during transcranial magnetic stimulation 失效
标题翻译：经颅磁刺激监测磁共振图像的方法和装置
公开(公告)号：US06198958B1
公开(公告)日：2001-03-06
申请号：US09096725
申请日：1998-06-11
申请人： John R. Ives , Alvaro Pascual-Leone , Qun Chen
发明人： John R. Ives , Alvaro Pascual-Leone , Qun Chen
IPC分类号： A61B505
CPC分类号： G01R33/4808 , A61B5/055 , A61B2090/374 , A61N2/006 , G01R33/56308
摘要： A method and apparatus for monitoring a magnetic resonance image of a patient during administration of transcranial magnetic stimulation. The method includes the steps of applying transcranial magnetic stimulation (TMS) to a patient using a probe that is substantially constructed of non-ferromagnetic material, monitoring a magnetic resonance image (MRI) of the patient during TMS wherein application of the TMS does not need to by synchronized to monitoring of the MRI.
摘要翻译：一种用于在施用经颅磁刺激期间监测患者的磁共振图像的方法和装置。该方法包括以下步骤：使用基本上由非铁磁材料构成的探针将经颅磁刺激（TMS）应用于患者，在TMS期间监测患者的磁共振图像（MRI），其中TMS的应用不需要通过同步监测MRI。

10. 发明授权

US06352599B1 High performance iron-rare earth-boron-refractory-cobalt nanocomposite 有权
$High performance iron-rare earth-boron-refractory-cobalt nanocomposite$
标题翻译：高性能铁 - 稀土 - 硼 - 难熔钴纳米复合材料
公开(公告)号：US06352599B1
公开(公告)日：2002-03-05
申请号：US09351760
申请日：1999-07-12
申请人： Wen Cheng Chang , Bao-Min Ma , Qun Chen , Charles O. Bounds
发明人： Wen Cheng Chang , Bao-Min Ma , Qun Chen , Charles O. Bounds
IPC分类号： H01F1057
CPC分类号： C04B35/58064 , B22F9/007 , B22F2998/00 , B82Y25/00 , C04B35/5156 , C04B35/58071 , C04B35/58078 , C04B35/653 , C22C1/0441 , H01F1/0578 , H01F1/0579 , B22F1/0018 , B22F9/008
摘要： Magnetic nanocomposite materials including iron, rare earth elements, boron, refractory metals and cobalt which have favorable magnetic properties and are suitable for making bonded magnets are disclosed. Compositions of the present invention can be of the formula: (N1−yLay)vFe100−v−w−x−zCowMzBx, where M is at least one refractory metal selected from Ti, Zr, Hf, V, Nb, Ta, Cr, Mo and W; v is from about 5 to about 15; w is greater than or equal to 5; x is from about 9 to about 30; y is from about 0.05 to about 0.5; and z is from about 0.1 to about 5. Preferably M is at least Cr. These materials have good magnetic properties and are suitable for use in preparing bonded magnets.
摘要翻译：公开了包含铁，稀土元素，硼，难熔金属和钴的磁性纳米复合材料，其具有良好的磁性并且适用于制造粘结磁体。本发明的组合物可以具有下式：（N1-yLay）vFe100-v-w-x-zCowMzBx，其中M是选自Ti，Zr，Hf，V，Nb，Ta，Cr，Mo和W中的至少一种难熔金属; v为约5至约15; w大于或等于5; x为约9至约30; y为约0.05至约0.5; 并且z为约0.1至约5.优选M至少为Cr。这些材料具有良好的磁性能，适用于制备粘结磁体。

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