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1. 发明申请

US20100041029A1 SYNTHESIS OF FOUR COLOR 3'O-ALLYL, MODIFIED PHOTOCLEAVABLE FLUORESCENT NUCLEOTIDES AND RELATED METHODS 有权
标题翻译：四色三聚体的合成，改性的光致变色荧光核和相关方法
公开(公告)号：US20100041029A1
公开(公告)日：2010-02-18
申请号：US12084338
申请日：2006-10-31
申请人： Jingyue Ju , Qinglin Meng , Dae H. Kim , Lanrong Bi , Xiaopeng Bai , Nicholas J. Turro
发明人： Jingyue Ju , Qinglin Meng , Dae H. Kim , Lanrong Bi , Xiaopeng Bai , Nicholas J. Turro
IPC分类号： C12Q1/68 , C07H21/04
CPC分类号： C12Q1/6806 , C07H1/04 , C07H19/067 , C07H19/10 , C07H19/14 , C12Q1/6869 , C12Q1/6874 , C12Q2521/101 , C12Q2525/117 , C12Q2525/186 , C12Q2563/107
摘要： This invention provides a process for making 3′-O-allyl-dGTP-PC-Biodopy-FL-510, 3′-O-allyl-dATP-PC-ROX, 3′-O-allyl-dCTP-PC- and 3′-O-allyl-dUTP-PC-R6G, and related methods.
摘要翻译：本发明提供了制备3'-O-烯丙基-DGTP-PC-生物反应-FL-510,3'- O-烯丙基-DATP-PC-ROX，3'-O-烯丙基-dCTP-PC-和3 '-O-烯丙基-dUTP-PC-R6G及相关方法。

2. 发明授权

US07982029B2 Synthesis of four color 3′O-allyl, modified photocleavable fluorescent nucleotides and related methods 有权
标题翻译：四色3'O-烯丙基，修饰的可光裂解荧光核苷酸的合成及相关方法
公开(公告)号：US07982029B2
公开(公告)日：2011-07-19
申请号：US12084338
申请日：2006-10-31
申请人： Jingyue Ju , Qinglin Meng , Dae H. Kim , Lanrong Bi , Xiaopeng Bai , Nicholas J. Turro
发明人： Jingyue Ju , Qinglin Meng , Dae H. Kim , Lanrong Bi , Xiaopeng Bai , Nicholas J. Turro
IPC分类号： C07H21/00 , C07H21/02 , C12Q1/68 , C12P19/34
CPC分类号： C12Q1/6806 , C07H1/04 , C07H19/067 , C07H19/10 , C07H19/14 , C12Q1/6869 , C12Q1/6874 , C12Q2521/101 , C12Q2525/117 , C12Q2525/186 , C12Q2563/107
摘要： This invention provides a process for making 3′-O-allyl-dGTP-PC-Biodopy-FL-510, 3′-O-allyl-dATP-PC-ROX, 3′-O-allyl-dCTP-PC-Bodipy-650 and 3′-O-allyl-dUTP-PC-R6G, and related methods.
摘要翻译：本发明提供了制备3'-O-烯丙基-dGTP-PC-生物反应-FL-510,3'- O-烯丙基-DATP-PC-ROX，3'-O-烯丙基-dCTP-PC- 650和3'-O-烯丙基-dUTP-PC-R6G及相关方法。

3. 发明授权

US09255292B2 Synthesis of four-color 3′-O-allyl modified photocleavable fluorescent nucleotides and related methods 有权
标题翻译：四色3'-O-烯丙基修饰的可透光荧光核苷酸的合成及相关方法
公开(公告)号：US09255292B2
公开(公告)日：2016-02-09
申请号：US13186353
申请日：2011-07-19
申请人： Jingyue Ju , Qinglin Meng , Dae H. Kim , Lanrong Bi , Xiaopeng Bai , Nicholas J. Turro
发明人： Jingyue Ju , Qinglin Meng , Dae H. Kim , Lanrong Bi , Xiaopeng Bai , Nicholas J. Turro
IPC分类号： C12Q1/68 , C12P19/34 , C07H19/067 , C07H19/04
CPC分类号： C12Q1/6806 , C07H1/04 , C07H19/067 , C07H19/10 , C07H19/14 , C12Q1/6869 , C12Q1/6874 , C12Q2521/101 , C12Q2525/117 , C12Q2525/186 , C12Q2563/107
摘要： This invention provides a process for making 3′-O-allyl-dGTP-PC-Biodopy-FL-510, 3′-O-allyl-dATP-PC-ROX, 3′-O-allyl-dCTP-PC-Bodipy-650 and 3′-O-allyl-dUTP-PC-R6G, and related methods.
摘要翻译：本发明提供了制备3'-O-烯丙基-dGTP-PC-生物反应-FL-510,3'- O-烯丙基-DATP-PC-ROX，3'-O-烯丙基-dCTP-PC- 650和3'-O-烯丙基-dUTP-PC-R6G及相关方法。

4. 发明申请

US20120156680A1 SYNTHESIS OF FOUR-COLOR 3'-O-ALLYL MODIFIED PHOTOCLEAVABLE FLUORESCENT NUCLEOTIDES AND RELATED METHODS 有权
标题翻译：四色素3'-O-全变体可光化荧光核苷的合成及相关方法
公开(公告)号：US20120156680A1
公开(公告)日：2012-06-21
申请号：US13186353
申请日：2011-07-19
申请人： Jingyue Ju , Qinglin Meng , Dae H. Kim , Lanrong Bi , Xiaopeng Bai , Nicholas J. Turro
发明人： Jingyue Ju , Qinglin Meng , Dae H. Kim , Lanrong Bi , Xiaopeng Bai , Nicholas J. Turro
IPC分类号： C12Q1/68
CPC分类号： C12Q1/6806 , C07H1/04 , C07H19/067 , C07H19/10 , C07H19/14 , C12Q1/6869 , C12Q1/6874 , C12Q2521/101 , C12Q2525/117 , C12Q2525/186 , C12Q2563/107
摘要： This invention provides a process for making 3′-O-allyl-dGTP-PC-Biodopy-FL-510, 3′-O-allyl-dATP-PC-ROX, 3′-O-allyl-dCTP-PC-Bodipy-650 and 3′-O-allyl-dUTP-PC-R6G, and related methods.
摘要翻译：本发明提供了制备3'-O-烯丙基-dGTP-PC-生物反应-FL-510,3'- O-烯丙基-DATP-PC-ROX，3'-O-烯丙基-dCTP-PC- 650和3'-O-烯丙基-dUTP-PC-R6G及相关方法。

5. 发明申请

US20090088332A1 Multiplex Digital Immuno-Sensing Using a Library of Photocleavable Mass Tags 审中-公开
标题翻译：可复制质量标签库的多路数字免疫检测
公开(公告)号：US20090088332A1
公开(公告)日：2009-04-02
申请号：US12085343
申请日：2006-11-20
申请人： Jingyue Ju , Xiaopeng Bai , Nicholas J. Turro
发明人： Jingyue Ju , Xiaopeng Bai , Nicholas J. Turro
IPC分类号： C40B30/04 , C40B40/10
CPC分类号： G01N33/6848
摘要： This invention provides methods, compositions and kits for immunosensing using photocleavable mass tags.
摘要翻译：本发明提供使用可光修复的质量标签进行免疫感测的方法，组合物和试剂盒。

6. 发明申请

US20100331441A1 FUNCTIONALIZATION OF ORGANIC SURFACES 有权
标题翻译：有机表面的功能化
公开(公告)号：US20100331441A1
公开(公告)日：2010-12-30
申请号：US12796462
申请日：2010-06-08
申请人： Jeffrey LANCASTER , Nicholas J. Turro , Jeffrey T. Koberstein
发明人： Jeffrey LANCASTER , Nicholas J. Turro , Jeffrey T. Koberstein
IPC分类号： C08J3/28 , C07D209/48 , C08F112/08 , C08F120/06
CPC分类号： C08J3/28 , C07D209/49
摘要： The present invention relates to functionalizing a surface of an organic material. For example, surfaces of materials having C—H bonds, such as polymers having C—H bonds, can be functionalized. In certain embodiments, a heterobifunctional molecule having a photoactive anchor, a spacer, and a terminal functional group is applied to the surface of an organic material that contains one or more C—H bonds. The heterobifunctional molecule can be bound to any surface having C—H bonds as the photoactive anchor can react with C—H bonds upon irradiation. The terminal functional group has a “click” functionality which can be utilized to functionalize the surface of the organic material with any desired functionalizing moiety having the orthogonal click functionality.
摘要翻译：本发明涉及官能化有机材料的表面。例如，具有C-H键的材料的表面，例如具有C-H键的聚合物，可以被官能化。在某些实施方案中，具有光活性锚，间隔基和末端官能团的异双功能分子被施加到含有一个或多个C-H键的有机材料的表面上。异双功能分子可以与具有C-H键的任何表面结合，因为光活性锚可以在照射时与C-H键反应。末端官能团具有“点击”功能，其可用于利用具有正交点击功能的任何所需官能化部分官能化有机材料的表面。

7. 发明授权

US5110425A Terminal chlorination of normal alkane hydrocarbons 失效
标题翻译：正烷烃的末端氯化
公开(公告)号：US5110425A
公开(公告)日：1992-05-05
申请号：US596728
申请日：1990-10-10
申请人： Nicholas J. Turro , James R. Fehlner
发明人： Nicholas J. Turro , James R. Fehlner
IPC分类号： C07B39/00 , C07C17/10 , C07C45/63 , C07C253/30 , C07C255/02
CPC分类号： C07C255/02 , C07B39/00 , C07C17/10 , C07C253/30 , C07C45/63
摘要： A terminally chlorinated normal alkane hydrocarbon is produced at high terminal selectivity, by adsorbing a normal alkane into a select zeolite and chlorinating the adsorbed alkane in the zeolite. The zeolite may be of a type having internal channels of diameter slightly larger than that of the alkane, and substantially no internal chambers, and may be selected from the pentasil family of zeolites. The chlorination reaction may be conducted under heating to enhance terminal selectivity even further, in many cases to levels approaching 100%.
摘要翻译：通过将正烷烃吸附到选择沸石中并对沸石中吸附的烷烃进行氯化，以高的末端选择性生产末端氯化的正烷烃。沸石可以是具有直径略大于烷烃的内部通道的类型，并且基本上没有内部室，并且可以选自pentasil沸石族。氯化反应可以在加热下进行，以进一步提高终端选择性，在许多情况下可达到接近100％的水平。

8. 发明申请

US20110059264A1 MODIFICATION OF SURFACES WITH NANOPARTICLES 有权
标题翻译：用纳米粒子修饰表面
公开(公告)号：US20110059264A1
公开(公告)日：2011-03-10
申请号：US12844635
申请日：2010-07-27
申请人： Ellane J. Park , Nicholas J. Turro , Jeffrey T. Koberstein
发明人： Ellane J. Park , Nicholas J. Turro , Jeffrey T. Koberstein
IPC分类号： C08F2/50 , C08J7/04
CPC分类号： C08J7/18 , C08J2325/06 , C09D1/00 , C09D7/62 , C09D7/67
摘要： Methods for functionalizing a surface of a substrate with nanoparticles are described. In certain embodiments, the method can include attaching a plurality of photoactive linker to nanoparticles to obtain photoactive nanoparticles, wherein each photoactive linker comprises a binding group that attaches to the nanoparticles and a photoactive group; depositing the photoactive nanoparticles to the surface of the substrate, wherein the surface of the substrate comprises reactive groups that are capable of reacting with the photoactive groups; and irradiating the photoactive nanoparticles with radiation to react the photoactive group with the reactive group and to functionalize the surface of the substrate with nanoparticles. In certain embodiments, the method can include attaching a plurality of photoactive linker to a surface of a substrate to obtain a photoactive surface, wherein each photoactive linker comprises a photoactive group and a binding group that attaches to the surface of the substrate; depositing nanoparticles to the photoactive surface, wherein the nanoparticles comprise reactive groups that are capable of reacting with the photoactive groups; and irradiating the photoactive surface with radiation to react the photoactive group with the reactive group to functionalize the surface of the substrate with nanoparticles.
摘要翻译：描述了用纳米颗粒官能化底物表面的方法。在某些实施方案中，该方法可以包括将多个光活性连接体连接到纳米颗粒以获得光活性纳米颗粒，其中每个光活性连接体包含附着于纳米颗粒和光活性基团的结合基团; 将光敏纳米颗粒沉积到基底的表面，其中基底的表面包含能够与光活性基团反应的反应性基团; 并用辐射照射光活性纳米颗粒以使光活性基团与反应性基团反应，并用纳米颗粒使基底的表面官能化。在某些实施方案中，该方法可以包括将多个光活性连接体连接到底物的表面以获得光活性表面，其中每个光活性连接体包含光活性基团和连接到基底表面的结合基团; 将纳米颗粒沉积到光敏表面，其中所述纳米颗粒包含能够与光活性基团反应的反应性基团; 并用辐射照射光活性表面以使光活性基团与反应性基团反应，以用纳米颗粒使基底的表面官能化。

9. 发明申请

US20100099580A1 Photochemical methods and photoactive compounds for modifying surfaces 有权
标题翻译：用于改性表面的光化学方法和光敏化合物
公开(公告)号：US20100099580A1
公开(公告)日：2010-04-22
申请号：US11595292
申请日：2006-11-09
申请人： Gregory T. Carroll , Jeffrey T. Koberstein , Denong Wang , Nicholas J. Turro
发明人： Gregory T. Carroll , Jeffrey T. Koberstein , Denong Wang , Nicholas J. Turro
IPC分类号： C07C69/76 , C07D403/04 , C07F7/02 , B05D3/06 , C08J7/04 , G03F7/20 , C40B40/04 , C40B40/12
CPC分类号： C07C49/303 , B05D3/06 , B05D3/067 , B05D5/00 , B05D7/02 , B05D7/14 , C07C69/76 , C07D209/48 , C23C18/1612 , C23C18/1641 , C23C18/30 , C23C18/32 , G03F7/0045 , G03F7/20
摘要： Compounds and methods for controlling the surface properties are described. Compounds of the invention can form radicals upon exposure to irradiation, which can then react with nearby molecules to alter the surface properties of various substrates. The invention can provide surfaces that are resistant to dewetting, surfaces that have immobilized molecules such as carbohydrates and polymers immobilized, and surfaces that have metals deposited on the surface. The invention can be utilized in a wide range of application, such as sensors, microreactors, microarrays, electroless deposition of metals, and the like.
摘要翻译：描述了用于控制表面性质的化合物和方法。本发明的化合物可以在暴露于辐射下形成自由基，然后其可以与附近的分子反应以改变各种底物的表面性质。本发明可以提供耐脱湿的表面，具有固定化分子的表面，例如碳水化合物和聚合物固定的表面，以及在表面上沉积金属的表面。本发明可以用于广泛的应用，例如传感器，微反应器，微阵列，金属的无电沉积等。

10. 发明授权

US09296870B2 Modification of surfaces with nanoparticles 有权
标题翻译：用纳米粒子改性表面
公开(公告)号：US09296870B2
公开(公告)日：2016-03-29
申请号：US12844635
申请日：2010-07-27
申请人： Ellane J. Park , Nicholas J. Turro , Jeffrey T. Koberstein
发明人： Ellane J. Park , Nicholas J. Turro , Jeffrey T. Koberstein
IPC分类号： C08J7/18 , C09D1/00 , C09D7/12
CPC分类号： C08J7/18 , C08J2325/06 , C09D1/00 , C09D7/62 , C09D7/67
摘要： Methods for functionalizing a surface of a substrate with nanoparticles are described. In certain embodiments, the method can include attaching a plurality of photoactive linker to nanoparticles to obtain photoactive nanoparticles, wherein each photoactive linker comprises a binding group that attaches to the nanoparticles and a photoactive group; depositing the photoactive nanoparticles to the surface of the substrate, wherein the surface of the substrate comprises reactive groups that are capable of reacting with the photoactive groups; and irradiating the photoactive nanoparticles with radiation to react the photoactive group with the reactive group and to functionalize the surface of the substrate with nanoparticles. In certain embodiments, the method can include attaching a plurality of photoactive linker linkers to a surface of a substrate to obtain a photoactive surface, wherein each photoactive linker comprises a photoactive group and a binding group that attaches to the surface of the substrate; depositing nanoparticles to the photoactive surface, wherein the nanoparticles comprise reactive groups that are capable of reacting with the photoactive groups; and irradiating the photoactive surface with radiation to react the photoactive group with the reactive group to functionalize the surface of the substrate with nanoparticles.
摘要翻译：描述了用纳米颗粒官能化底物表面的方法。在某些实施方案中，该方法可以包括将多个光活性连接体连接到纳米颗粒以获得光活性纳米颗粒，其中每个光活性连接体包含附着于纳米颗粒和光活性基团的结合基团; 将光敏纳米颗粒沉积到基底的表面，其中基底的表面包含能够与光活性基团反应的反应性基团; 并用辐射照射光活性纳米颗粒以使光活性基团与反应性基团反应，并用纳米颗粒使基底的表面官能化。在某些实施方案中，该方法可以包括将多个光活性连接物连接体连接到基底表面以获得光活性表面，其中每个光活性连接体包含光活性基团和附着到基底表面的结合基团; 将纳米颗粒沉积到光敏表面，其中所述纳米颗粒包含能够与光活性基团反应的反应性基团; 并用辐射照射光活性表面以使光活性基团与反应性基团反应，以用纳米颗粒使基底的表面官能化。

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