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1. 发明申请

US20090324073A1 METHOD OF REARRANGING A CLUSTER MAP OF VOXELS IN AN IMAGE 有权
标题翻译：在图像中重新定位VOXELS的聚类映射的方法
公开(公告)号：US20090324073A1
公开(公告)日：2009-12-31
申请号：US12375754
申请日：2007-07-30
申请人： Mark Christof Wengler , Alexander Fischer
发明人： Mark Christof Wengler , Alexander Fischer
IPC分类号： G06K9/62 , G06T7/00
CPC分类号： G06K9/6218 , G06K9/033 , G06K9/38 , G06T7/11 , G06T7/136 , G06T7/143 , G06T2200/04 , G06T2207/10072 , G06T2207/20036 , G06T2207/30004
摘要： This invention relates to rearranging a cluster map of voxels in an image aiming at the reduction of sub-cluster scatter. The cluster map that includes two or more cluster levels is displayed to the user along with the distribution of the voxels within each respective cluster levels. The aim is to enable the user to evaluate the quality of the cluster map and based on the evaluation to change the distribution of the voxels. Such a change in the distribution will result in an update of the cluster map.
摘要翻译：本发明涉及重新排列旨在减少子群落散射的图像中的体素的聚类映射。包含两个或多个集群级别的集群映射与每个相应集群级别中的体素分布一起显示给用户。目的是使用户能够评估集群映射的质量，并根据评估改变体素的分布。分配的这种变化将导致集群映射的更新。

2. 发明申请

US20090324035A1 METHOD OF COMBINING BINARY CLUSTER MAPS INTO A SINGLE CLUSTER MAP 审中-公开
标题翻译：将二进制集群组合成单个集群映射的方法
公开(公告)号：US20090324035A1
公开(公告)日：2009-12-31
申请号：US12375747
申请日：2007-07-17
申请人： Mark Christof Wengler , Timo Paulus , Alexander Fischer
发明人： Mark Christof Wengler , Timo Paulus , Alexander Fischer
IPC分类号： G06K9/62 , G06T7/00
CPC分类号： G06K9/6253 , G06K9/6218 , G06K9/6292 , G06K9/6293 , G06T7/0012 , G06T7/11 , G06T7/143 , G06T2207/10072 , G06T2207/30004
摘要： This invention relates to a method of combining multiple binary cluster maps into a single cluster map; where each respective binary cluster map represents characteristic information and the single cluster map represent the sum of the characteristic information. Initially, each respective binary cluster map is assigned with a reliability factor for indicating the reliability of the binary cluster map. These factor values are then used to determine a reliability vector comprising reliability factor elements, where each respective reliability factor element is associated to certain cluster map area in the single cluster map and indicates the reliability of cluster map are. In that way, the single cluster map can be viewed with respect to the reliability.
摘要翻译：本发明涉及将多个二进制簇映射组合成单个簇映射的方法; 其中每个相应的二进制集群映射表示特征信息，并且单个集群映射表示特征信息的和。首先，为每个相应的二进制簇映射分配用于指示二进制簇映射的可靠性的可靠性因子。然后使用这些因子值来确定包括可靠性因素元素的可靠性向量，其中每个相应的可靠性因素元素与单个聚类映射中的某些聚类映射区域相关联并且指示聚类映射的可靠性。以这种方式，可以相对于可靠性来查看单个集群映射。

3. 发明授权

US08189929B2 Method of rearranging a cluster map of voxels in an image 有权
标题翻译：重新排列图像中体素的集群映射的方法
公开(公告)号：US08189929B2
公开(公告)日：2012-05-29
申请号：US12375754
申请日：2007-07-30
申请人： Mark Christof Wengler , Alexander Fischer
发明人： Mark Christof Wengler , Alexander Fischer
IPC分类号： G06K9/62 , G06K9/00
CPC分类号： G06K9/6218 , G06K9/033 , G06K9/38 , G06T7/11 , G06T7/136 , G06T7/143 , G06T2200/04 , G06T2207/10072 , G06T2207/20036 , G06T2207/30004
摘要： This invention relates to rearranging a cluster map of voxels in an image aiming at the reduction of sub-cluster scatter. The cluster map that includes two or more cluster levels is displayed to the user along with the distribution of the voxels within each respective cluster levels. The aim is to enable the user to evaluate the quality of the cluster map and based on the evaluation to change the distribution of the voxels. Such a change in the distribution will result in an update of the cluster map.
摘要翻译：本发明涉及重新排列旨在减少子群落散射的图像中的体素的聚类映射。包含两个或多个集群级别的集群映射与每个相应集群级别中的体素分布一起显示给用户。目的是使用户能够评估集群映射的质量，并根据评估改变体素的分布。分配的这种变化将导致集群映射的更新。

4. 发明授权

US08811708B2 Quantification of medical image data 有权
标题翻译：医学图像数据的量化
公开(公告)号：US08811708B2
公开(公告)日：2014-08-19
申请号：US13263764
申请日：2010-04-12
申请人： Alexander Fischer , Uma Satya Ranjan , Utpal Kumar
发明人： Alexander Fischer , Uma Satya Ranjan , Utpal Kumar
IPC分类号： G06K9/00 , G06K9/32 , G06T3/00 , G06T7/00
CPC分类号： G06T7/0012 , G06T7/30 , G06T2207/10072 , G06T2207/20104 , G06T2207/30004
摘要： A system is provided for quantification of medical image data. First image obtaining means (1) are for obtaining a first image (A). Second image obtaining means (2) are for obtaining a second image (B). Spatial transformation obtaining means (3) are for obtaining spatial transformation information representing a correspondence between points in the first image and corresponding points in the second image. Identifying means (4) are for identifying a first image region (C) in the first image (A). Transforming means (5) are for transforming the first image region (C) into a corresponding second image region C′) in the second image (B) based on the spatial transformation information. Quantification means (6) are for computing a quantification relating to the second image region (C′) by accessing image values of the second image (B) within the second image region (C′).
摘要翻译：提供用于定量医学图像数据的系统。第一图像获取装置（1）用于获得第一图像（A）。第二图像获取装置（2）用于获得第二图像（B）。空间变换获取装置（3）用于获得表示第一图像中的点与第二图像中的对应点之间的对应关系的空间变换信息。识别装置（4）用于识别第一图像（A）中的第一图像区域（C）。变换装置（5）用于基于空间变换信息将第一图像区域（C）变换为第二图像（B）中的对应的第二图像区域C'。量化装置（6）用于通过访问第二图像区域（C'）内的第二图像（B）的图像值来计算与第二图像区域（C'）有关的量化。

5. 发明申请

US20110081068A1 RADIOLOGICAL IMAGING INCORPORATING LOCAL MOTION MONITORING, CORRECTION, AND ASSESSMENT 失效
标题翻译：包含本地运动监测，校正和评估的放射成像
公开(公告)号：US20110081068A1
公开(公告)日：2011-04-07
申请号：US12996781
申请日：2009-06-01
申请人： Ralph Brinks , Alexander Fischer , Ana Belen Martin Recuero , Jens-Christoph Georgi , Bernd Schweizer , Timo Markus Paulus
发明人： Ralph Brinks , Alexander Fischer , Ana Belen Martin Recuero , Jens-Christoph Georgi , Bernd Schweizer , Timo Markus Paulus
IPC分类号： G06K9/00 , G01T1/164
CPC分类号： G06T11/005 , G06T2211/412
摘要： A radiological imaging method comprises: acquiring radiological lines of response (LOR's) from a subject; grouping the acquired LOR's into time intervals such that each group of LOR's (20) was acquired during a selected time interval; identifying a region of interest (60, 74) for each time interval based on LOR's grouped into that time interval; for each time interval, determining a positional characteristic (102) of the region of interest identified for that time interval based on LOR's grouped into that time interval; for each time interval, spatially adjusting LOR's grouped into that time interval based on the positional characteristic of the region of interest identified for that time interval; and reconstructing at least the spatially adjusted LOR's to generate a motion compensated reconstructed image.
摘要翻译：放射学成像方法包括：从受试者获取放射线响应（LOR）; 将获得的LOR分组成时间间隔，使得在选定的时间间隔内获取每组LOR（20）; 基于分组到该时间间隔中的LOR，为每个时间间隔识别感兴趣区域（60,74）; 对于每个时间间隔，基于分组到该时间间隔中的LOR确定针对该时间间隔标识的兴趣区域的位置特征（102）; 对于每个时间间隔，基于针对该时间间隔识别的感兴趣区域的位置特性，空间调整LOR被分组为该时间间隔; 以及至少重构空间调节的LOR以产生运动补偿重建图像。

6. 发明申请

US20090208075A1 ERROR ADAPTIVE FUNCTIONAL IIMAGING 有权
标题翻译：错误自适应功能模糊
公开(公告)号：US20090208075A1
公开(公告)日：2009-08-20
申请号：US12300341
申请日：2007-05-01
申请人： Alexander Fischer , Lothar Spies , Carsten Meyer
发明人： Alexander Fischer , Lothar Spies , Carsten Meyer
IPC分类号： G06K9/00 , G06N5/02
CPC分类号： G06T7/11 , G06K9/6218 , G06T2207/10104 , G06T2207/20016 , G06T2207/20021 , G06T2207/30096
摘要： A method for use in functional medical imaging includes adaptively partitioning functional imaging data as a function of a spatially varying error model. The functional image data is partitioned according to an optimization strategy. The data may be visualized or used to plan a course of treatment. In one implementation, the image data is partitioned so as to vary its spatial resolution. In another, the number of clusters is varied based on the error model.
摘要翻译：用于功能医学成像的方法包括根据空间变化的误差模型自适应地划分功能成像数据。功能图像数据根据优化策略进行分区。数据可以被可视化或用于计划治疗过程。在一个实现中，图像数据被分割以改变其空间分辨率。另一方面，群集的数量根据误差模型而变化。

7. 发明申请

US20090171183A1 PATIENT SCAN TIME OPTIMIZATION FOR PET/SPECT IMAGING 有权
标题翻译：患者扫描时间优化PET / SPECT成像
公开(公告)号：US20090171183A1
公开(公告)日：2009-07-02
申请号：US12088088
申请日：2006-09-15
申请人： Manoj Narayanan , Bart Jacob Bakker , Daniel Gagnon , Alexander Fischer , Lothar Spies
发明人： Manoj Narayanan , Bart Jacob Bakker , Daniel Gagnon , Alexander Fischer , Lothar Spies
IPC分类号： A61B5/05 , G06F19/00
CPC分类号： A61B6/00 , A61B6/037
摘要： An imaging system (10) comprises a data device (30), which controls radiation data acquisition from a subject positioned in an examination region (18) for an examination. A rebinning processor (40) bins the acquired data periodically into a histogram (42). A transform (70) transforms the histogram (42) into individual independent or uncorrelated components, each component including a signal content and a noise content. A stopping determining device (52) compares an aspect of at least one selected component to a predetermined threshold (TH) and, based on the comparison, terminates the data acquisition.
摘要翻译：成像系统（10）包括数据装置（30），其控制从位于检查区域（18）中的被摄体进行检查的辐射数据采集。重组处理器（40）将获取的数据周期性地存储到直方图（42）中。变换（70）将直方图（42）变换为独立的或不相关的分量，每个分量包括信号内容和噪声内容。停止确定装置（52）将至少一个所选择的组件的方面与预定阈值（TH）进行比较，并且基于该比较，终止数据采集。

8. 发明申请

US20080183447A1 Automatic Input Function Estimation For Pharmacokinetic Modeling 审中-公开
标题翻译：药代动力学建模的自动输入函数估计
公开(公告)号：US20080183447A1
公开(公告)日：2008-07-31
申请号：US11995829
申请日：2006-07-11
申请人： Alexander Fischer , Timo Paulus
发明人： Alexander Fischer , Timo Paulus
IPC分类号： G06N3/00 , G06F17/10 , G06G7/58
CPC分类号： G06F17/18 , G16H50/50
摘要： This system (200), apparatus (300), and method (100) of the present invention provide an analytic way to solve the (input) estimation problem of pharmacokinetic modeling: estimating parameters of a kinetic model from a series of tracer (radioactively labeled imaging agent) activity measurements (e.g. by positron emission tomography). Since the model describes a biological process its parameters have a direct functional interpretation (e.g. hypoxia for the tracer FMISO) that can be of diagnostic value. The measurements represent the activity distribution in time and space in the form of a 4D data set d(t, x, y, z), t=1, . . . , T. The kinetic parameter estimation procedure (205) requires knowledge of the tracer input activity. This input activity can either be measured invasively or it can be estimated from the data in a preprocessing step. The estimation problem can be solved efficiently if the model and its input are described analytically. Typically parameterized functions (often sums of exponential terms) (204) are fitted to the averaged data over a region of interest (ROI) (e.g. an artery or the left ventricular blood pool) in order to obtain an analytical input representation. The input function representation (functional form) (204) and its initial parameter values (205) have to be selected/specified prior to the fitting procedure 206). The present invention thereby reduces the amount of manual interaction and operator dependence in the evaluation of dynamic procedures.
摘要翻译：本发明的系统（200），装置（300）和方法（100）提供了解决药代动力学模型的（输入）估计问题的分析方法：从一系列示踪剂（放射性标记）估计动力学模型的参数成像剂）活性测量（例如通过正电子发射断层摄影）。由于该模型描述了生物过程，其参数具有可以具有诊断价值的直接功能解释（例如示踪剂FMISO的缺氧）。测量以4D数据集d（t，x，y，z），t = 1，...的形式表示时间和空间中的活动分布。。。动力学参数估计程序（205）需要了解示踪者输入活动的知识。该输入活动可以被入侵测量，也可以从预处理步骤中的数据估计。如果模型及其输入被分析地描述，则可以有效地解决估计问题。通常，参数化函数（通常指数项的和）（204）适合于感兴趣区域（ROI）（例如动脉或左心室血池）上的平均数据，以便获得分析输入表示。必须在拟合程序206之前选择/指定输入功能表示（功能形式）（204）及其初始参数值（205）。因此，本发明减少了在动态过程评估中手动交互和操作者依赖的量。

9. 发明授权

US06929052B2 Method and apparatus for uphill casting with a slide valve closure placed on the casting table 有权
标题翻译：用于上坡铸造的方法和装置，其具有放置在铸造台上的滑阀闭合
公开(公告)号：US06929052B2
公开(公告)日：2005-08-16
申请号：US10312938
申请日：2001-07-07
申请人： Alexander Fischer , Wolfgang Müller
发明人： Alexander Fischer , Wolfgang Müller
IPC分类号： B22D18/04 , B22D41/24
CPC分类号： B22D41/24 , B22D18/04
摘要： A method for uphill casting/low-pressure casting, especially of light metal alloys, with a casting furnace lying below a casting table, having a riser pipe and a mouth opening of the riser pipe and having a mould with an underlying pouring-in opening and having a slide valve closure, forming a flow-through channel which for casting takes on a substantially straight, longitudinal course, wherein for shut-off in the slide valve closure, two opening sections of the flow-through channel directly adjacent one to the other are displaced with respect to one another transversely to the longitudinal course of the flow-through channel directly after casting with still liquid melt in the pouring-in opening, so that an overlying opening section remains in open communication with the pouring-in opening free from undercut and an underlying opening section remains in open communication with the mouth opening of the riser pipe, wherein the opening sections are completely offset with respect to each other.
摘要翻译：一种用于上浇铸/低压铸造，特别是轻金属合金的方法，其具有位于铸造台下方的铸造炉，具有提升管和提升管的开口，并具有具有下面的入口的模具并且具有滑阀闭合件，形成用于铸造的流通通道基本上是直的纵向过程，其中为了在滑阀闭合件中切断，流动通道的两个开口部分直接邻近于另一个在浇注入口中的静止液体熔体之后直接相对于另一个横向相对于流通通道的纵向进行位移，使得上部开口部分保持与入口开口自由开放连通从底切和下面的开口部分保持与提升管的开口开放连通，其中开口部分相对于每个ot完全偏移她

10. 发明授权

US06713191B2 Surface-alloyed cylindrical, partially cylindrical or hollow cylindrical component 有权
标题翻译：表面合金圆柱形，部分圆柱形或中空圆柱形部件
公开(公告)号：US06713191B2
公开(公告)日：2004-03-30
申请号：US10019974
申请日：2002-05-22
申请人： Josef Franz Feikus , Alexander Fischer
发明人： Josef Franz Feikus , Alexander Fischer
IPC分类号： B32B1504
CPC分类号： B23K26/0823 , B23K26/32 , B23K26/34 , B23K2103/08 , B23K2103/10 , C23C4/16 , C23C24/10 , C23C26/02 , Y10T428/12535 , Y10T428/12674 , Y10T428/12736 , Y10T428/12764 , Y10T428/13 , Y10T428/2495 , Y10T428/24983
摘要： A surface-alloyed cylindrical, partly cylindrical or hollow cylindrical component consists of an aluminium matrix casting alloy (1) and a precipitation area (3) extending as far as the surface of the component (3) and consisting of an aluminium base alloy with precipitated hard phases. A eutectic area (2) (hereafter: “transition area”) which is supersaturated by primary hard phases is present between the matrix (1) and the precipitation area (3) and the increase in hardness from the matrix (1) to the component surface (3) is gradual.
摘要翻译：表面合金化的圆柱形，部分圆柱形或中空圆柱形部件由铝基体铸造合金（1）和延伸至部件（3）的表面的沉淀区域（3）组成，并由沉淀的铝基合金硬阶段在基质（1）和沉淀区域（3）之间存在由初级硬相过饱和的共晶区域（以下称为“过渡区域”），并且从基质（1）到组分表面（3）是渐进的。

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