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1. 发明授权

US08795188B2 Device and method for a medical intervention 有权
标题翻译：用于医疗干预的装置和方法
公开(公告)号：US08795188B2
公开(公告)日：2014-08-05
申请号：US12433950
申请日：2009-05-01
申请人： Michael Maschke
发明人： Michael Maschke
IPC分类号： A61B19/00 , A61B17/00
CPC分类号： A61B6/4464 , A61B5/1135 , A61B6/12 , A61B6/4458 , A61B6/5288 , A61B6/541 , A61B34/30 , A61B2017/00119 , A61B2017/00694 , A61B2017/00699 , A61B2034/2051 , A61B2090/376
摘要： The invention relates to a device and a method for a medical intervention on a patient. The device provided for carrying out the method comprises a medical instrument that is to be introduced into a moving body region of the patient, a robot which has a plurality of degrees of freedom of movement and on which the medical instrument can be disposed for guiding, and means for recording the movement of the body region, wherein the medical instrument can be introduced into the body region of the patient by means of the robot taking into account the movement of the body region and guided in the direction of a target tissue in the body of the patient.
摘要翻译：本发明涉及一种用于患者的医疗干预的装置和方法。提供用于执行该方法的装置包括被引入到患者的移动体区域中的医疗器械，具有多个移动自由度的机器人，并且可以在其上设置用于引导的医疗器械，以及用于记录身体区域的移动的装置，其中可以借助机器人将医疗器械引入到身体区域中，同时考虑到身体区域的移动并且在目标组织的方向上引导病人身体

2. 发明授权

US08792964B2 Method and apparatus for conducting an interventional procedure involving heart valves using a robot-based X-ray device 有权
标题翻译：使用基于机器人的X射线装置进行涉及心脏瓣膜的介入手术的方法和装置
公开(公告)号：US08792964B2
公开(公告)日：2014-07-29
申请号：US12046727
申请日：2008-03-12
申请人： Michael Maschke
发明人： Michael Maschke
IPC分类号： A61B5/05
CPC分类号： B25J15/0019 , A61B1/3137 , A61B5/01 , A61B5/0402 , A61B5/08 , A61B5/145 , A61B5/411 , A61B5/4821 , A61B6/12 , A61B6/4417 , A61B6/4441 , A61B6/4458 , A61B6/4464 , A61B6/503 , A61B6/541 , A61B8/0883 , A61B8/12 , A61B8/4416 , A61B34/20 , A61B34/30 , A61B34/71 , A61B2034/301 , A61B2090/364 , A61B2090/376
摘要： In a method and an apparatus for conducting minimally-invasive procedures involving heart valves at least one multi-access articulated x-ray imaging robot is employed that allows a radiation detector carried by the robot to be moved in arbitrary paths, such as in circle, an ellipse, or along a spiral, around a patient in order to generate multiple projection exposures of the relevant region of the patient during the procedure. An image processor reconstructs a 3D image from the projection exposures substantially in real time during the procedure, and the 3D image is displayed to operating personnel during the procedure.
摘要翻译：在涉及心脏瓣膜的用于进行微创手术的方法和装置中，采用至少一个多通道关节X射线成像机器人，其允许机器人携带的放射线检测器以任意路径（例如圆形）移动，椭圆形，或沿着螺旋形，围绕患者，以便在手术期间产生患者的相关区域的多个投影曝光。图像处理器在过程中基本上实时地从投影曝光中重建3D图像，并且在该过程期间将3D图像显示给操作人员。

3. 发明授权

US08611495B2 Biplane X-ray imaging system 失效
标题翻译：双平面X射线成像系统
公开(公告)号：US08611495B2
公开(公告)日：2013-12-17
申请号：US13103246
申请日：2011-05-09
申请人： Michael Maschke
发明人： Michael Maschke
IPC分类号： G01N23/04
CPC分类号： G03B42/02 , A61B6/4014 , A61B6/4021 , A61B6/4035 , A61B6/4064 , A61B6/4291 , A61B6/4417 , A61B6/4441 , A61B6/4458 , A61B6/4464 , A61B6/484 , A61B6/487 , G01N23/046 , G01N2223/419 , G01N2223/612 , G03B42/026 , G21K2207/005
摘要： A biplane X-ray imaging system is provided. The biplane X-ray imaging system has two recording units disposed in different planes. Each of the recording units has an X-ray detector and an X-ray source. The first recording unit is a phase-contrast recording unit for phase-contrast X-ray imaging. The second recording unit is a conventional recording unit for conventional x-ray imaging.
摘要翻译：提供双平面X射线成像系统。双平面X射线成像系统具有设置在不同平面中的两个记录单元。每个记录单元都具有X射线检测器和X射线源。第一记录单元是用于相位对比度X射线成像的相差记录单元。第二记录单元是用于常规x射线成像的常规记录单元。

4. 发明授权

US08382372B2 Medical apparatus 有权
标题翻译：医疗器械
公开(公告)号：US08382372B2
公开(公告)日：2013-02-26
申请号：US12499145
申请日：2009-07-08
申请人： Michael Maschke
发明人： Michael Maschke
IPC分类号： G01N23/04 , H05G1/00 , A61B6/12 , A61B5/05
CPC分类号： A61B6/04 , A61B5/06 , A61B5/062 , A61B5/064 , A61B6/102 , A61B6/12 , A61B6/4441 , A61B6/4458 , A61B6/467 , A61B6/584 , A61G13/0036
摘要： The invention relates to a medical apparatus. The medical apparatus includes a patient support table with a patient support plate, a medical imaging device, a location and navigation facility integrated at least partially in the patient support table and/or the medical imaging device and a system controller, which is used to operate and/or control both the medical imaging device and also the location and navigation facility.
摘要翻译：本发明涉及医疗装置。医疗装置包括具有患者支撑板的患者支撑台，医疗成像装置，至少部分地集成在患者支撑台和/或医疗成像装置中的位置和导航装置以及用于操作的系统控制器和/或控制医学成像设备以及位置和导航设施。

5. 发明授权

US08337512B2 Device and workflow for minimally-invasive therapy, in particular needle guidance 有权
标题翻译：用于微创治疗的装置和工作流程，特别是针引导
公开(公告)号：US08337512B2
公开(公告)日：2012-12-25
申请号：US12329831
申请日：2008-12-08
申请人： Michael Maschke
发明人： Michael Maschke
IPC分类号： A61B19/00
CPC分类号： A61M16/0096 , A61B17/3403 , A61B2017/00699 , A61B2017/3409
摘要： In a method or system for minimally-invasive therapy on a patient, a minimally-invasive therapy apparatus is provided. While performing the minimally-invasive therapy on the patient with a minimally-invasive therapy apparatus, the patient is ventilated with a jet ventilator to reduce a magnitude of the patient's breathing and increase a frequency of the patient's breathing.
摘要翻译：在用于对患者进行微创治疗的方法或系统中，提供了微创治疗装置。在用微创治疗设备对患者进行微创治疗的同时，患者通过喷气呼吸机通气，以减少患者呼吸的程度并增加患者呼吸的频率。

6. 发明授权

US08295434B2 X-ray imaging method and x-ray imaging system 有权
标题翻译： X射线成像方法和X射线成像系统
公开(公告)号：US08295434B2
公开(公告)日：2012-10-23
申请号：US12890775
申请日：2010-09-27
申请人： Jan Boese , Michael Maschke
发明人： Jan Boese , Michael Maschke
IPC分类号： G01N23/04
CPC分类号： H01J35/065 , A61B6/06 , A61B6/5282 , G21K1/025 , G21K2207/00 , H01J2235/062 , H01J2235/068
摘要： A method for recording an x-ray image with an x-ray imaging system having an x-ray source and an x-ray detector is provided. The x-ray source has a plurality of x-ray emitters arranged alongside one another. Each x-ray emitter is assigned to a part area of the x-ray detector. The x-ray beam generated by the x-ray emitter is collimated onto the assigned part area. A first x-ray emitter is activated for emitting a first x-ray beam onto a first part area and image data of the first part area is read out. Subsequently a further x-ray emitter for emitting a further x-ray beam onto a further part area of is activated and image data of the further part area is read out. The steps are repeated until image data for all part areas of the x-ray detector is read out. The read out image data is combined into an x-ray image.
摘要翻译：提供了一种用具有X射线源和X射线检测器的X射线成像系统记录X射线图像的方法。 x射线源具有彼此并排布置的多个x射线发射器。每个x射线发射器被分配到x射线检测器的一部分区域。由x射线发射器产生的X射线束被准直到分配的部分区域。第一x射线发射器被激活用于将第一x射线束发射到第一部分区域上，并且读出第一部分区域的图像数据。随后，用于将另外的X射线束发射到另一部分区域上的另外的X射线发射器被激活，并且读出另外的部分区域的图像数据。重复这些步骤，直到读出x射线检测器的所有部分区域的图像数据。读出的图像数据被组合成X射线图像。

7. 发明授权

US08109951B2 Device for implementing a cutting balloon intervention with IVUS monitoring 有权
标题翻译：用于通过IVUS监测实现切割气球干预的装置
公开(公告)号：US08109951B2
公开(公告)日：2012-02-07
申请号：US11093452
申请日：2005-03-30
申请人： Michael Maschke
发明人： Michael Maschke
IPC分类号： A61B17/22
CPC分类号： A61B17/320725 , A61B2017/22061 , A61B2090/3784
摘要： Device for implementing a cutting balloon intervention by means of a “cutting balloon” catheter, at the distal end of which is disposed an inflatable balloon with axially running blades mounted thereon, and which has IVUS monitoring, whereby the cutting balloon catheter is combined with an IVUS catheter to form an integrated module.
摘要翻译：用于通过“切割气囊”导管实施切割气囊介入的装置，其在其远端设置有可安装在其上的轴向运行的叶片的可充气气囊，并且具有IVUS监测，由此将切割气囊导管与 IVUS导管形成一体化模块。

8. 发明申请

US20110280379A1 Imaging apparatus comprising a ring-shaped gantry 有权
标题翻译：成像设备包括环形台架
公开(公告)号：US20110280379A1
公开(公告)日：2011-11-17
申请号：US13105015
申请日：2011-05-11
申请人： Michael Maschke
发明人： Michael Maschke
IPC分类号： H05G1/02 , B82Y99/00
CPC分类号： A61B6/4435 , A61B6/4411 , A61B6/4441 , A61B6/4458 , A61B6/4464
摘要： An imaging apparatus comprising a ring-shaped gantry is provided. The gantry has a rotor arrangement rotating therein and a radiation source as well as at least one radiation detector. The gantry has at least one gantry segment which can be detached from the ring shape to allow the gantry to be opened laterally. The gantry is arranged on a supporting structure so as to be movable in space. The supporting structure is a floor, wall or ceiling mounted articulated-arm robot having at least four, preferably six, degrees of freedom of movement. The gantry has at least two radiation sources disposed offset by an angle on the rotor arrangement and associated with each of which is at least one radiation detector.
摘要翻译：提供了一种包括环形台架的成像设备。台架具有在其中旋转的转子布置和辐射源以及至少一个辐射检测器。台架具有至少一个可从环形分离的龙门架部分，以便台架横向打开。台架布置在支撑结构上，以便在空间中可移动。支撑结构是具有至少四个，优选六个自由度的地板，墙壁或天花板安装的铰接臂机器人。台架具有至少两个在转子装置上偏移角度的辐射源，并且每个辐射源与至少一个辐射探测器相关联。

9. 发明申请

US20110218380A1 Magnetic nanoparticle and group of nanoparticles 有权
标题翻译：磁性纳米颗粒和纳米颗粒组
公开(公告)号：US20110218380A1
公开(公告)日：2011-09-08
申请号：US13036065
申请日：2011-02-28
申请人： Michael Maschke
发明人： Michael Maschke
IPC分类号： A61M37/00 , A61K49/04 , A61P9/00 , B82Y5/00
CPC分类号： B82Y5/00 , A61K9/0009 , A61K9/5094 , A61K9/5115 , A61K9/5138 , A61K9/5146 , A61K49/0409 , A61K2035/124 , A61M5/007 , C12N11/00 , C12N11/14
摘要： For particularly effective stem cell therapy a nanoparticle is provided. The nanoparticle has a first element consisting of a magnetic material, a support or envelope element consisting of a biodegradable material, a first substance containing an x-ray contrast agent, and a second substance containing stem cells. The stem cells are embodied such that they can be used for angiogenesis or for myogenesis.
摘要翻译：对于特别有效的干细胞治疗，提供了纳米颗粒。纳米颗粒具有由磁性材料构成的第一元件，由可生物降解材料构成的支撑体或包络元件，含有X射线造影剂的第一物质和含有干细胞的第二物质。干细胞被体现为使得它们可用于血管发生或用于肌发生。

10. 发明申请

US20110196395A1 Method for displaying an image of the inside of a vessel lying in front of an expander device and display device corresponding hereto 审中-公开
标题翻译：用于显示位于扩展器装置前面的容器的内部的图像和与其对应的显示装置的方法
公开(公告)号：US20110196395A1
公开(公告)日：2011-08-11
申请号：US13021928
申请日：2011-02-07
申请人： Michael Maschke
发明人： Michael Maschke
IPC分类号： A61B17/22
CPC分类号： A61B17/320758 , A61B5/0084 , A61B5/02007 , A61B5/055 , A61B5/061 , A61B8/0858 , A61B8/12 , A61B2090/3782 , A61M2025/09175
摘要： A guide wire featuring a tip is introduced into a vessel. An expander tool featuring a tip is introduced by pushing it over the guide wire into the vessel. For the expander tool introduced into the vessel at least one image is output to the operator of the expander tool via a viewing device. The image is a representation of the area of the inside of the vessel which, seen in a local direction of advance of the expander tool, lies directly in front of the tip of the expander tool. The image is determined on the basis of at least one image dataset which was acquired by at least one sensor. The at least one sensor is arranged at the tip of the guide wire or on the expander tool behind its tip.
摘要翻译：将特征为尖端的引导线引入到容器中。通过将引导线推到容器中，引入具有尖端的膨胀器工具。对于引入到容器中的扩张器工具，至少一个图像经由观察装置输出到膨胀器工具的操作者。该图像是在膨胀器工具的局部方向上看到的容器内部的区域的表示，其直接位于膨胀器工具的尖端的前方。基于由至少一个传感器获取的至少一个图像数据集来确定图像。所述至少一个传感器布置在所述导丝的尖端处或在所述扩展器工具的尖端之后。

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