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1. 发明授权

US09987461B2 Hemodialysis catheter with thrombus blocker 有权
公开(公告)号：US09987461B2
公开(公告)日：2018-06-05
申请号：US12903677
申请日：2010-10-13
申请人： Michael W. Hardert , Michael R. Kurrus
发明人： Michael W. Hardert , Michael R. Kurrus
IPC分类号： A61M25/00 , A61M1/36
CPC分类号： A61M25/0026 , A61M1/3661
摘要： A hemodialysis catheter with a plurality of umbrella-like wire members covered with a film which works as a thrombus blocker and can easily and effectively remove the thrombus is disclosed. The hemodialysis catheter has a proximal lumen, the arterial lumen, and a distal lumen, the venous lumen. An elongate member is longitudinally put in either the proximal lumen or the distal lumen, or two elongate members in both lumens. A plurality of umbrella-like wire members are connected to the end of the elongate member. When the hemodialysis catheter is put in the vessel but not in use, the end of the lumen is capped off by the plurality of umbrella-like wire members covered with a film. When it is ready to use, the doctor can pull the elongate member which connects to the plurality of umbrella-like wire members out off the lumen inverting the plurality of umbrella-like wire members and clearing away any thrombus that has formed.

2. 发明授权

US08246568B2 Hemodialysis catheter with thrombus removing device 有权
标题翻译：血液透析导管与血栓去除装置
公开(公告)号：US08246568B2
公开(公告)日：2012-08-21
申请号：US12551030
申请日：2009-08-31
申请人： Michael W. Hardert , Michael R. Kurrus , Amy Lee Hruska , Tyson L. Rugenstein , Elizabeth A. Theobald
发明人： Michael W. Hardert , Michael R. Kurrus , Amy Lee Hruska , Tyson L. Rugenstein , Elizabeth A. Theobald
IPC分类号： A61M37/00 , A61M31/00
CPC分类号： A61M25/0068 , A61M25/0075 , A61M2025/0019 , A61M2025/0031 , A61M2025/0037 , A61M2025/004
摘要： The present disclosure provides apparatus and methods for removing thrombus outside of a hemodialysis. The hemodialysis catheter comprises an elongate shaft comprising a plurality of lumens. A first lumen has a first distal port. The first lumen is configured for the flow of a fluid in a first direction. A second lumen has a second distal port proximal to the first distal port. The second lumen is configured for the flow of the fluid in a second direction opposite to the first direction. A third lumen has a third distal port proximal to the second distal port. An elongate device is disposed through the third lumen. The elongate device has an operable member on a distal end or a device to connect to an operable member disposed on the elongate shaft. The operable member is configured to engage and remove thrombus from an exterior surface on the elongate shaft.
摘要翻译：本公开提供了用于去除血液透析以外的血栓的装置和方法。血液透析导管包括包括多个腔的细长轴。第一管腔具有第一远端口。第一管腔构造成用于沿第一方向流动流体。第二管腔具有靠近第一远端口的第二远端口。第二管腔构造成用于在与第一方向相反的第二方向上流动流体。第三管腔具有靠近第二远端口的第三远端端口。细长装置设置穿过第三腔。细长装置具有在远端上的可操作构件或连接到设置在细长轴上的可操作构件的装置。可操作构件构造成从细长轴上的外表面接合和去除血栓。

3. 发明申请

US20120095416A1 HEMODIALYSIS CATHETER WITH THROMBUS BLOCKER 有权
标题翻译： HEMODIALYSIS导管与THROMBUS阻塞器
公开(公告)号：US20120095416A1
公开(公告)日：2012-04-19
申请号：US12903677
申请日：2010-10-13
申请人： Michael W. Hardert , Michael R. Kurrus
发明人： Michael W. Hardert , Michael R. Kurrus
IPC分类号： A61M25/00
CPC分类号： A61M25/0026 , A61M1/3661
摘要： A hemodialysis catheter with a plurality of umbrella-like wire members covered with a film which works as a thrombus blocker and can easily and effectively remove the thrombus is disclosed. The hemodialysis catheter has a proximal lumen, the arterial lumen, and a distal lumen, the venous lumen. An elongate member is longitudinally put in either the proximal lumen or the distal lumen, or two elongate members in both lumens. A plurality of umbrella-like wire members are connected to the end of the elongate member. When the hemodialysis catheter is put in the vessel but not in use, the end of the lumen is capped off by the plurality of umbrella-like wire members covered with a film. When it is ready to use, the doctor can pull the elongate member which connects to the plurality of umbrella-like wire members out off the lumen inverting the plurality of umbrella-like wire members and clearing away any thrombus that has formed.
摘要翻译：公开了一种血液透析导管，其具有覆盖有膜的多个伞形线构件，其作为血栓阻断剂起作用并且可以容易且有效地去除血栓。血液透析导管具有近端内腔，动脉腔和远端腔，即静脉腔。纵向放置在近端内腔或远端腔中的细长构件或两个内腔中的两个细长构件。多个伞形线构件连接到细长构件的端部。当血液透析导管放入容器但不使用时，通过被膜覆盖的多个伞形线构件将管腔的端部封盖。当它准备使用时，医生可以将连接到多个伞形线构件的细长构件拉出反射多个伞形线构件的内腔，并清除已经形成的任何血栓。

4. 发明申请

US20110054379A1 HEMODIALYSIS CATHETER WITH THROMBUS REMOVING DEVICE 有权
标题翻译： HEMODIALYSIS导管与THROMBUS移除装置
公开(公告)号：US20110054379A1
公开(公告)日：2011-03-03
申请号：US12551030
申请日：2009-08-31
申请人： Michael W. Hardert , Michael R. Kurrus , Amy Lee Hruska , Tyson L. Rugenstein , Elizabeth A. Theobald
发明人： Michael W. Hardert , Michael R. Kurrus , Amy Lee Hruska , Tyson L. Rugenstein , Elizabeth A. Theobald
IPC分类号： A61M1/34
CPC分类号： A61M25/0068 , A61M25/0075 , A61M2025/0019 , A61M2025/0031 , A61M2025/0037 , A61M2025/004
摘要： The present disclosure provides apparatus and methods for removing thrombus outside of a hemodialysis. The hemodialysis catheter comprises an elongate shaft comprising a plurality of lumens. A first lumen has a first distal port. The first lumen is configured for the flow of a fluid in a first direction. A second lumen has a second distal port proximal to the first distal port. The second lumen is configured for the flow of the fluid in a second direction opposite to the first direction. A third lumen has a third distal port proximal to the second distal port. An elongate device is disposed through the third lumen. The elongate device has an operable member on a distal end or a device to connect to an operable member disposed on the elongate shaft. The operable member is configured to engage and remove thrombus from an exterior surface on the elongate shaft.
摘要翻译：本公开提供了用于去除血液透析以外的血栓的装置和方法。血液透析导管包括包括多个腔的细长轴。第一管腔具有第一远端口。第一管腔构造成用于沿第一方向流动流体。第二管腔具有靠近第一远端口的第二远端口。第二管腔构造成用于在与第一方向相反的第二方向上流动流体。第三管腔具有靠近第二远端口的第三远端端口。细长装置设置穿过第三腔。细长装置具有在远端上的可操作构件或连接到设置在细长轴上的可操作构件的装置。可操作构件构造成从细长轴上的外表面接合和去除血栓。

5. 发明申请

US20100234878A1 CLOSURE DEVICE WITH STRING RETRACTABLE UMBRELLA 有权
标题翻译：闭合装置带有可回缩的UMBRELLA
公开(公告)号：US20100234878A1
公开(公告)日：2010-09-16
申请号：US12404652
申请日：2009-03-16
申请人： Christopher L. Hruska , Michael W. Hardert
发明人： Christopher L. Hruska , Michael W. Hardert
IPC分类号： A61B17/08
CPC分类号： A61B17/0057 , A61B2017/00597 , A61B2017/00606 , A61B2017/00623 , A61B2017/00867 , A61B2017/0496
摘要： A repositionable closure device for occluding a body opening is provided. The closure device includes distal and proximal occluding bodies having expandable distal and proximal umbrella frames. Each umbrella frame includes a plurality of struts connected to a biocompatible sheet material. The distal and proximal umbrella frames expand to expanded configurations on opposite sides of the body opening. The struts of the distal umbrella frame terminate with an eyelet. The distal occluding body is connected to a distal end of a center rod and the proximal umbrella frame is slidable along the center rod via a center ring. At least one drawstring is threaded through the eyelets and the center ring, connecting the distal and proximal occluding bodies. The drawstring extends proximally from the center ring. Manipulation of the drawstring and the center rod is configured to collapse the closure device for at least partial retrieval during repositioning.
摘要翻译：提供了一种用于封闭体开口的可重新定位的闭合装置。闭合装置包括具有可扩展的远侧和近侧伞形框架的远端和近端闭塞体。每个伞形框架包括连接到生物相容片材的多个支柱。远端和近侧伞架在主体开口的相对侧上膨胀成扩展构型。远侧伞架的支柱用孔眼终止。远侧闭塞体连接到中心杆的远端，并且近侧伞形框架可以经由中心环沿着中心杆滑动。至少一条束带穿过孔眼和中心环，连接远端和近端闭塞体。束带从中心环向近端延伸。束带和中心杆的操纵被配置为在重新定位期间使封闭装置折叠至少部分恢复。

6. 发明申请

US20100106178A1 VASCULAR PLUGS 有权
标题翻译：血管插管
公开(公告)号：US20100106178A1
公开(公告)日：2010-04-29
申请号：US12608243
申请日：2009-10-29
申请人： F. Joseph Obermiller , Michael D. Deckard , Kathryn Evert , Michael W. Hardert
发明人： F. Joseph Obermiller , Michael D. Deckard , Kathryn Evert , Michael W. Hardert
IPC分类号： A61M29/00
CPC分类号： A61B17/12109 , A61B17/0057 , A61B17/12022 , A61B17/12031 , A61B17/12159 , A61B17/12172 , A61B17/12177 , A61B17/1219 , A61B2017/12054
摘要： Certain aspects of the present invention provide devices for occluding vascular vessels. In some preferred forms, these devices are able to move from a first condition to a less compact, second condition in a vascular vessel so as to fully or partially prevent fluid from passing through the vessel. One such device includes a frame and a flexible sheet material. The device also includes an occluding material that is located in an interior region of the frame. The flexible sheet material and frame are associated with one another such that when the device is in the second condition in the vascular vessel, the sheet material is positioned in the vessel lumen so as to block fluid flow through the lumen.
摘要翻译：本发明的某些方面提供用于阻塞血管的装置。在一些优选的形式中，这些装置能够在血管容器中从第一状态移动到较不致密的第二状态，以便完全或部分地防止流体通过血管。一种这样的装置包括框架和柔性片材。该装置还包括位于框架的内部区域中的阻塞材料。柔性片材和框架彼此相关联，使得当装置在血管容器中处于第二状态时，片材材料被定位在血管腔中，以阻止流体流过管腔。

7. 发明申请

US20120165850A1 Spring Action Medical Device 有权
标题翻译：弹簧动作医疗器械
公开(公告)号：US20120165850A1
公开(公告)日：2012-06-28
申请号：US13379975
申请日：2010-07-08
申请人： Michael D. Deckard , Michael W. Hardert , Thomas A. Kay, JR. , William F. Moore , James C. Elsesser , David C. Lentz , Jeffry S. Melsheimer
发明人： Michael D. Deckard , Michael W. Hardert , Thomas A. Kay, JR. , William F. Moore , James C. Elsesser , David C. Lentz , Jeffry S. Melsheimer
IPC分类号： A61B17/34
CPC分类号： A61M25/09025 , A61B17/22012 , A61B2017/22038 , A61B2017/22069 , A61B2017/22094
摘要： A spring action medical device includes a spring that may propel a hammer component in a distal direction when the spring is released from a loaded state. When propelled forward by the spring, the hammer component makes contact with a distal tip of the medical device. The distal tip may then transfer a force to an external object, such as an occlusion in a body lumen.
摘要翻译：弹簧动作医疗装置包括弹簧，当弹簧从负载状态释放时，弹簧可以沿远侧方向推进锤部件。当弹簧向前推进时，锤子部件与医疗装置的远端接触。然后，远侧末端可以将力传递到外部物体，例如体腔内的闭塞。

8. 发明授权

US08123770B2 Angioplasty cutting device and method for treating a stenotic lesion in a body vessel 有权
标题翻译：血管成形术切割装置和用于治疗体内血管狭窄病变的方法
公开(公告)号：US08123770B2
公开(公告)日：2012-02-28
申请号：US11591050
申请日：2006-11-01
申请人： Kian Olsen , Mark J. Hiatt , Michael W. Hardert
发明人： Kian Olsen , Mark J. Hiatt , Michael W. Hardert
IPC分类号： A61B17/22
CPC分类号： A61B17/320725 , A61B17/320758 , A61B2017/00477 , A61B2017/22061 , A61M25/104 , A61M2025/1086 , A61M2025/109
摘要： An integrally formed angioplasty cutting device for balloon angioplasty of a stenotic lesion in a body vessel. The device comprises a distal collar and a proximal collar. The device further comprises at least one strut integrally formed with the distal collar and the proximal collar. At least one of the collars has a slot formed therethrough defining a C-shaped configuration. The strut is configured to be disposed at the stenotic lesion to engage the stenotic lesion for dilatation of the body vessel during angioplasty.
摘要翻译：一种整体形成的用于球体血管成形术的血管成形术切割装置，其用于体内血管中的狭窄病变。该装置包括远侧套环和近端套环。所述装置还包括至少一个与所述远侧套环和所述近侧颈圈一体形成的支柱。所述套环中的至少一个具有穿过其形成的狭槽，其形成为C形构造。支柱被配置为设置在狭窄病变处以接合狭窄病变以在血管成形术期间扩张体血管。

9. 发明申请

US20110295228A1 MINIMALLY INVASIVE MEDICAL DEVICE AND METHOD FOR DELIVERY OF THERAPEUTIC OR DIAGNOSTIC AGENTS INTO A VESSEL WALL 有权
标题翻译：最小的入侵医疗装置和将治疗或诊断代谢物输送到血管壁的方法
公开(公告)号：US20110295228A1
公开(公告)日：2011-12-01
申请号：US13209145
申请日：2011-08-12
申请人： Brad Shirley , Grant T. Hoffman , Michael W. Hardert , Jeffry S. Melsheimer
发明人： Brad Shirley , Grant T. Hoffman , Michael W. Hardert , Jeffry S. Melsheimer
IPC分类号： A61M31/00
CPC分类号： A61M25/0084
摘要： The invention relates to minimally invasive device for delivering therapeutic or diagnostic agents into a vessel wall. The device includes an introducer tube, a tubular member having a proximal end, a distal end, and a first lumen extending therebetween, the tubular member being slidably disposed within the introducer tube; a plurality of hollow delivery struts, each delivery strut adapted to pierce through inner most layers of the vessel wall and each comprising at least one exit port and at least one stopper to prevent the delivery strut from piercing through the outer most layers of the vessel wall. The delivery struts are disposed on the distal end of the tubular member and are in fluid communication with the first lumen. The invention also relates to methods of delivering the device of this invention and methods of treating conditions or diseases of body lumens.
摘要翻译：本发明涉及用于将治疗剂或诊断剂递送到血管壁中的微创装置。所述装置包括导引管，管状构件，其具有近端，远端和在其间延伸的第一腔，所述管状构件可滑动地设置在所述导引管内; 多个中空输送支柱，每个输送支柱适于刺穿血管壁的最内层，并且每个输送支柱包括至少一个出口和至少一个塞子，以防止输送支柱穿过血管壁的最外层。输送支柱设置在管状构件的远端上并与第一腔流体连通。本发明还涉及递送本发明的装置的方法和治疗体腔的病症或疾病的方法。

10. 发明申请

US20090018638A1 Minimally invasive medical device and method for delivery of therapeutic or diagnostic agents into a vessel wall 有权
标题翻译：用于将治疗剂或诊断剂递送到血管壁的微创医疗装置和方法
公开(公告)号：US20090018638A1
公开(公告)日：2009-01-15
申请号：US11827219
申请日：2007-07-10
申请人： Brad Shirley , Grant T. Hoffman , Michael W. Hardert , Jeffry S. Melsheimer
发明人： Brad Shirley , Grant T. Hoffman , Michael W. Hardert , Jeffry S. Melsheimer
IPC分类号： A61F2/06 , A61M31/00 , A61M5/178
CPC分类号： A61M25/0084
摘要： The invention relates to minimally invasive device for delivering therapeutic or diagnostic agents into a vessel wall. The device includes an introducer tube, a tubular member having a proximal end, a distal end, and a first lumen extending therebetween, the tubular member being slidably disposed within the introducer tube; a plurality of hollow delivery struts, each delivery strut adapted to pierce through inner most layers of the vessel wall and each comprising at least one exit port and at least one stopper to prevent the delivery strut from piercing through the outer most layers of the vessel wall. The delivery struts are disposed on the distal end of the tubular member and are in fluid communication with the first lumen. The invention also relates to methods of delivering the device of this invention and methods of treating conditions or diseases of body lumens.
摘要翻译：本发明涉及用于将治疗剂或诊断剂递送到血管壁中的微创装置。所述装置包括导引管，管状构件，其具有近端，远端和在其间延伸的第一腔，所述管状构件可滑动地设置在所述导引管内; 多个中空输送支柱，每个输送支柱适于刺穿血管壁的最内层，并且每个输送支柱包括至少一个出口和至少一个塞子，以防止输送支柱穿过血管壁的最外层。输送支柱设置在管状构件的远端上并与第一腔流体连通。本发明还涉及递送本发明的装置的方法和治疗体腔的病症或疾病的方法。

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