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1. 发明授权

US08625865B2 Method and apparatus for navigating a therapeutic device to a location 失效
标题翻译：用于将治疗装置导航到位置的方法和装置
公开(公告)号：US08625865B2
公开(公告)日：2014-01-07
申请号：US12937717
申请日：2008-04-17
申请人： Michael Zarkh , Amir Blumenfeld , Moshe Klaiman
发明人： Michael Zarkh , Amir Blumenfeld , Moshe Klaiman
IPC分类号： G06K9/00
CPC分类号： A61B6/12 , A61B6/481 , A61B6/504
摘要： A method and apparatus for navigating a therapeutic device to a location in a moving organ. A feature is identified in one reference image, such as a calcified spot. Then the target location for the device is determined. If the feature and the target location are not shown on the same frame, registration is performed, and the geometric relation between the feature and the target location is determined. On the positioning stage, the feature is identified in a positioning image, then the target location is indicated on the image. The user then manipulates the device, also visible on the positioning image to the target location. If the feature is not identified automatically in the positioning image, the target location is assumed at the current location, and the feature is marked, which assists the user in identifying the real location of the feature, and manipulating the device to the target location.
摘要翻译：一种用于将治疗装置导航到移动器官中的位置的方法和装置。在一个参考图像中识别特征，例如钙化斑点。然后确定设备的目标位置。如果特征和目标位置未在同一帧上显示，则执行注册，并确定特征与目标位置之间的几何关系。在定位阶段，在定位图像中识别特征，然后在图像上指示目标位置。用户然后操纵设备，也可以在定位图像上看到目标位置。如果在定位图像中没有自动识别该特征，则在当前位置处假定目标位置，并标记该特征，这有助于用户识别该特征的实际位置，并将该装置操纵到该目标位置。

2. 发明申请

US20110033094A1 METHOD AND APPARATUS FOR NAVIGATING A THERAPEUTIC DEVICE TO A LOCATION 失效
标题翻译：将治疗设备引导到位置的方法和装置
公开(公告)号：US20110033094A1
公开(公告)日：2011-02-10
申请号：US12937717
申请日：2008-04-17
申请人： Michael Zarkh , Amir Blumenfeld , Moshe Klaiman
发明人： Michael Zarkh , Amir Blumenfeld , Moshe Klaiman
IPC分类号： G06K9/00
CPC分类号： A61B6/12 , A61B6/481 , A61B6/504
摘要： A method and apparatus for navigating a therapeutic device to a location in a moving organ. A feature is identified in one reference image, such as a calcified spot. Then the target location for the device is determined. If the feature and the target location are not shown on the same frame, registration is performed, and the geometric relation between the feature and the target location is determined. On the positioning stage, the feature is identified in a positioning image, then the target location is indicated on the image. The user then manipulates the device, also visible on the positioning image to the target location. If the feature is not identified automatically in the positioning image, the target location is assumed at the current location, and the feature is marked, which assists the user in identifying the real location of the feature, and manipulating the device to the target location.
摘要翻译：一种用于将治疗装置导航到移动器官中的位置的方法和装置。在一个参考图像中识别特征，例如钙化斑点。然后确定设备的目标位置。如果特征和目标位置未在同一帧上显示，则执行注册，并确定特征与目标位置之间的几何关系。在定位阶段，在定位图像中识别特征，然后在图像上指示目标位置。用户然后操纵设备，也可以在定位图像上看到目标位置。如果在定位图像中没有自动识别特征，则在当前位置处假定目标位置，并且标记该特征，这有助于用户识别特征的实际位置，并将该装置操纵到目标位置。

3. 发明申请

US20060074285A1 Apparatus and method for fusion and in-operating-room presentation of volumetric data and 3-D angiographic data 审中-公开
标题翻译：用于融合和手术室呈现体积数据和3-D血管造影数据的装置和方法
公开(公告)号：US20060074285A1
公开(公告)日：2006-04-06
申请号：US10949155
申请日：2004-09-24
申请人： Michael Zarkh , Omer Barlev , Moshe Klaiman
发明人： Michael Zarkh , Omer Barlev , Moshe Klaiman
IPC分类号： A61B5/05
CPC分类号： A61B6/504 , G06T7/33 , G06T7/38 , G06T2207/30101
摘要： An apparatus and method for fusing images, views and data acquired prior to a medical operation by a medical imaging device with images, views and data acquired by another medical imaging device during the operation. The acquired and fused data includes identification and classification of plaque deposited along blood vessels.
摘要翻译：一种用于在由医疗成像设备进行医疗操作之前获取的图像，视图和数据的装置和方法，其具有在操作期间由另一医疗成像设备获取的图像，视图和数据。获得和融合的数据包括沿着血管沉积的斑块的鉴定和分类。

4. 发明申请

US20100312100A1 METHOD AND APPARATUS FOR GUIDING A DEVICE IN A TOTALLY OCCLUDED OR PARTLY OCCLUDED TUBULAR ORGAN 失效
标题翻译：用于指导设备在全部或部分管理的管状器件中的方法和装置
公开(公告)号：US20100312100A1
公开(公告)日：2010-12-09
申请号：US12446459
申请日：2006-10-22
申请人： Michael Zarkh , Moshe Klaiman
发明人： Michael Zarkh , Moshe Klaiman
IPC分类号： A61B5/05 , G06K9/00
CPC分类号： A61B6/12 , A61B6/541 , G06K9/4638 , G06K2209/057 , G06T3/0068 , G06T7/32 , G06T2207/10072 , G06T2207/10116 , G06T2207/20016 , G06T2207/30021 , G06T2207/30101
摘要： An apparatus and method for detecting, tracking and registering a device (218) within a tubular organ (210) of a subject. The devices include guide wire (216) tip or therapeutic devices, and the detection and tracking uses fluoroscopic images taken prior to or during a catheterization operation. The devices are fused with images or projections of models depicting tile tubular organs. Tile method and apparatus are used for treating chronic total occlusion or near total occlusion situations, by navigating a driller along the tubular organ (210) proximally to the occlusion point, in areas which are-not viewable in an angiogram, and optionally enabling the penetration of the occlusion in a preferred area.
摘要翻译：一种用于检测，跟踪和记录受试者的管状器官（210）内的装置（218）的装置和方法。这些装置包括引导线（216）尖端或治疗装置，并且检测和跟踪使用在导管插入术之前或期间拍摄的荧光透视图像。这些装置与描绘瓦片管状器官的模型的图像或投影融合。瓦片方法和装置用于治疗慢性完全闭塞或接近完全闭塞的情况，通过沿着管状器官（210）向近侧导航到闭塞点，在血管造影中不可见的区域中，并且可选地使穿透的闭塞在优选区域。

5. 发明申请

US20090216112A1 Method and apparatus for positioning a biventrivular pacemaker lead and electrode 有权
标题翻译：用于定位双向起搏器引线和电极的方法和装置
公开(公告)号：US20090216112A1
公开(公告)日：2009-08-27
申请号：US11912840
申请日：2005-05-03
申请人： Tsuriel Assis , Moshe Klaiman , Michael Zarkh
发明人： Tsuriel Assis , Moshe Klaiman , Michael Zarkh
IPC分类号： A61B6/00 , A61N1/372
CPC分类号： A61B6/12 , A61B6/466 , A61B6/481 , A61B6/504 , A61B6/5235 , A61N1/08
摘要： An apparatus and method for placing a device in a body area of a patient, by: tracking the device over a 3-dimensional model of the body area; activating the device at different locations in the body area; measuring the response signal or parameter caused by the activation; storing the locations as well as the response signals; choosing an optimal location for the device base in the stored response signals and navigating the device to the optimal location.
摘要翻译：一种用于通过以下方式将装置放置在患者的身体区域中的装置和方法：通过在身体区域的三维模型上跟踪装置; 在身体区域的不同位置激活装置; 测量由激活引起的响应信号或参数; 存储位置以及响应信号; 在存储的响应信号中选择设备基础的最佳位置，并将设备导航到最佳位置。

6. 发明授权

US08700128B2 Method and apparatus for positioning a biventrivular pacemaker lead and electrode 有权
标题翻译：用于定位双向起搏器引线和电极的方法和装置
公开(公告)号：US08700128B2
公开(公告)日：2014-04-15
申请号：US11912840
申请日：2005-05-03
申请人： Tsuriel Assis , Moshe Klaiman , Michael Zarkh
发明人： Tsuriel Assis , Moshe Klaiman , Michael Zarkh
IPC分类号： A61B6/00
CPC分类号： A61B6/12 , A61B6/466 , A61B6/481 , A61B6/504 , A61B6/5235 , A61N1/08
摘要： An apparatus and method for placing a device in a body area of a patient, by: tracking the device over a 3-dimensional model of the body area; activating the device at different locations in the body area; measuring the response signal or parameter caused by the activation; storing the locations as well as the response signals; choosing an optimal location for the device base in the stored response signals and navigating the device to the optimal location.
摘要翻译：一种用于通过以下方式将装置放置在患者的身体区域中的装置和方法：通过在身体区域的三维模型上跟踪装置; 在身体区域的不同位置激活装置; 测量由激活引起的响应信号或参数; 存储位置以及响应信号; 在存储的响应信号中选择设备基础的最佳位置，并将设备导航到最佳位置。

7. 发明授权

US07587074B2 Method and system for identifying optimal image within a series of images that depict a moving organ 失效
标题翻译：用于识别描绘移动器官的一系列图像内的最佳图像的方法和系统
公开(公告)号：US07587074B2
公开(公告)日：2009-09-08
申请号：US10565224
申请日：2004-07-14
申请人： Michael Zarkh , Moshe Klaiman
发明人： Michael Zarkh , Moshe Klaiman
IPC分类号： G06K9/00
CPC分类号： G06T11/005 , A61B5/7285 , A61B6/503 , A61B6/504 , A61B6/541 , G06T7/20 , G06T2211/404 , G06T2211/412
摘要： A method and system for quantifying a cyclic motion within a series of images depicting a moving object subject to composite motion containing a cyclic component and a non-cyclic component of lower frequency than the cyclic component. Composite motion is computed as well as the non-cyclic component as the integral of motion over a motion cycle. The non-cyclic component is subtracted from the composite motion so as to obtain the cyclic component
摘要翻译：一种用于量化一系列图像内的循环运动的方法和系统，其描绘经受包含比循环分量低的频率的循环分量和非循环分量的复合运动的运动物体。计算复合运动以及作为运动周期运动的积分的非循环分量。从复合运动中减去非循环分量，以获得循环分量

8. 发明申请

US20070116342A1 System and method for three-dimensional reconstruction of a tubular organ 失效
标题翻译：管状器官三维重建的系统和方法
公开(公告)号：US20070116342A1
公开(公告)日：2007-05-24
申请号：US10573464
申请日：2004-09-24
申请人： Michael Zarkh , Moshe Klaiman
发明人： Michael Zarkh , Moshe Klaiman
IPC分类号： G06K9/00
CPC分类号： G06T7/564
摘要： Embodiments of the present invention include methods and systems for three-dimensional reconstruction of a tubular organ (for example, coronary artery) using a plurality of two-dimensional images. Some of the embodiments may include displaying a first image of a vascular network, receiving input for identifying on the first image a vessel of interest, tracing the edges of the vessel of interest including eliminating false edges of objects visually adjacent to the vessel of interest, determining substantially precise radius and densitometry values along the vessel, displaying at least a second image of the vascular network, receiving input for identifying on the second image the vessel of interest, tracing the edges of the vessel of interest in the second image, including eliminating false edges of objects visually adjacent to the vessel of interest, determining substantially precise radius and densitometry values along the vessel in the second image, determining a three dimensional reconstruction of the vessel of interest and determining fused area (cross-section) measurements along the vessel and computing and presenting quantitative measurements, including, but not limited to, true length, percent narrowing (diameter and area), and the like.
摘要翻译：本发明的实施例包括使用多个二维图像的管状器官（例如冠状动脉）的三维重建的方法和系统。一些实施例可以包括显示血管网络的第一图像，接收用于在第一图像上识别感兴趣血管的输入，跟踪感兴趣血管的边缘，包括消除视觉上与感兴趣血管相邻的物体的假边缘，确定沿着血管的基本上精确的半径和密度测定值，显示血管网络的至少第二图像，接收用于在第二图像上识别感兴趣血管的输入，跟踪第二图像中感兴趣血管的边缘，包括消除确定与目标血管视觉相邻的物体的假边缘，沿着第二图像中的血管确定基本上精确的半径和密度测定值，确定感兴趣的血管的三维重建并确定沿着血管的融合区域（横截面）测量并且计算和呈现定量测量，包括但不限于，真实长度，百分比变窄（直径和面积）等。

9. 发明授权

US07742629B2 System and method for three-dimensional reconstruction of a tubular organ 失效
标题翻译：管状器官三维重建的系统和方法
公开(公告)号：US07742629B2
公开(公告)日：2010-06-22
申请号：US10573464
申请日：2004-09-24
申请人： Michael Zarkh , Moshe Klaiman
发明人： Michael Zarkh , Moshe Klaiman
IPC分类号： G06K9/00 , G06K9/36
CPC分类号： G06T7/564
摘要： Embodiments of the present invention include methods and systems for three-dimensional reconstruction of a tubular organ (for example, coronary artery) using a plurality of two-dimensional images. Some of the embodiments may include displaying a first image of a vascular network, receiving input for identifying on the first image a vessel of interest, tracing the edges of the vessel of interest including eliminating false edges of objects visually adjacent to the vessel of interest, determining substantially precise radius and densitometry values along the vessel, displaying at least a second image of the vascular network, receiving input for identifying on the second image the vessel of interest, tracing the edges of the vessel of interest in the second image, including eliminating false edges of objects visually adjacent to the vessel of interest, determining substantially precise radius and densitometry values along the vessel in the second image, determining a three dimensional reconstruction of the vessel of interest and determining fused area (cross-section) measurements along the vessel and computing and presenting quantitative measurements, including, but not limited to, true length, percent narrowing (diameter and area), and the like.
摘要翻译：本发明的实施例包括使用多个二维图像的管状器官（例如冠状动脉）的三维重建的方法和系统。一些实施例可以包括显示血管网络的第一图像，接收用于在第一图像上识别感兴趣血管的输入，跟踪感兴趣血管的边缘，包括消除视觉上与感兴趣血管相邻的物体的假边缘，确定沿着血管的基本上精确的半径和密度测定值，显示血管网络的至少第二图像，接收用于在第二图像上识别感兴趣血管的输入，跟踪第二图像中感兴趣血管的边缘，包括消除确定与目标血管视觉相邻的物体的假边缘，沿着第二图像中的血管确定基本上精确的半径和密度测定值，确定感兴趣的血管的三维重建，并确定沿着血管的融合区域（横截面）测量并且计算和呈现定量测量，包括但不限于，真实长度，百分比变窄（直径和面积）等。

10. 发明申请

US20060188135A1 Method and system for identifying optimal image within a series of images that depict a moving organ 失效
公开(公告)号：US20060188135A1
公开(公告)日：2006-08-24
申请号：US10565224
申请日：2004-07-14
申请人： Michael Zarkh , Moshe Klaiman
发明人： Michael Zarkh , Moshe Klaiman
IPC分类号： G06K9/00
CPC分类号： G06T11/005 , A61B5/7285 , A61B6/503 , A61B6/504 , A61B6/541 , G06T7/20 , G06T2211/404 , G06T2211/412
摘要： A method and system for quantifying a cyclic motion within a series of images depicting a moving object subject to composite motion containing a cyclic component and a non-cyclic component of lower frequency than the cyclic component. Composite motion is computed as well as the non-cyclic component as the integral of motion over a motion cycle. The non-cyclic component is subtracted from the composite motion so as to obtain the cyclic component

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