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1. 发明申请

US20110222288A1 LIGHTING DEVICE 审中-公开
标题翻译：照明设备
公开(公告)号：US20110222288A1
公开(公告)日：2011-09-15
申请号：US13129902
申请日：2009-11-12
申请人： Michel C. J. M. Vissenberg , Maarten M. J. W. Van Herpen , Marcellinus P. C. M. Krijn , Oscar H. Willemsen , Ramon P. Van Gorkom , Tim Dekker
发明人： Michel C. J. M. Vissenberg , Maarten M. J. W. Van Herpen , Marcellinus P. C. M. Krijn , Oscar H. Willemsen , Ramon P. Van Gorkom , Tim Dekker
IPC分类号： F21V33/00 , H01L33/00 , F21V29/00
CPC分类号： F21V14/003 , F21V11/18 , F21V14/08 , F21V23/0442 , F21V23/0457 , F21Y2115/10
摘要： There is disclosed a lighting device of which the light sources and/or optical elements are hidden in a first cover state associated with a first light state. This enables an unobtrusive lighting system in the first cover state. In a second cover state associated with a second light state, optical elements, e.g. shutters or beam shaping elements, are switched, induced by the heat or the light flux generated by the light sources, such that the lighting system can function properly.
摘要翻译：公开了一种照明装置，其中光源和/或光学元件被隐藏在与第一光状态相关联的第一盖状态中。这使得在第一盖状态下的不引人注意的照明系统成为可能。在与第二光状态相关联的第二覆盖状态下，光学元件例如。百叶窗或光束成形元件由光源产生的热量或光通量进行切换，使得照明系统能够正常工作。

2. 发明授权

US08039818B2 Sub wavelength aperture 有权
标题翻译：子波长孔径
公开(公告)号：US08039818B2
公开(公告)日：2011-10-18
申请号：US12519800
申请日：2007-12-18
申请人： Maarten M. J. W. Van Herpen , Derk J. W. Klunder
发明人： Maarten M. J. W. Van Herpen , Derk J. W. Klunder
IPC分类号： G01N21/64
CPC分类号： G01N21/64 , G01N21/6445
摘要： There is provided a method of detecting a presence of a luminophore in a detection volume comprising providing excitation radiation in said detection volume. A luminophore is provided in said detection volume being excitable by said excitation radiation. The luminescent radiation is detected to identify the presence of said luminophore in said detection volume. In one aspect of the invention, said luminophore is selected to emit luminescent radiation having a wavelength in said medium that is larger than twice said smallest dimension; and wherein said luminophore is selected to be excitable by excitation radiation having a wavelength in said medium that is smaller than twice said smallest dimension. Accordingly, luminescent radiation is blocked from entering the detector but for the portion present on an interface of the aperture.
摘要翻译：提供了一种检测检测体积中的发光体的存在的方法，包括在所述检测体积中提供激发辐射。在所述检测体积中提供发光体，所述发光体可被所述激发辐射激发。检测发光辐射以识别所述检测体积中所述发光体的存在。在本发明的一个方面，所述发光体选择为发射具有大于所述最小尺寸的两倍的所述介质中的波长的发光辐射; 并且其中所述发光体被选择为通过所述介质中具有小于所述最小尺寸的两倍的波长的激发辐射来激发。因此，阻挡发光辐射进入检测器，但是阻挡存在于孔的界面上的部分。

3. 发明授权

US09176062B2 Aperture biosensor with trenches 有权
标题翻译：孔径生物传感器与沟槽
公开(公告)号：US09176062B2
公开(公告)日：2015-11-03
申请号：US12519849
申请日：2007-12-17
申请人： Derk J. W. Klunder , Maarten M. J. W. Van Herpen , Hendrik R. Stapert
发明人： Derk J. W. Klunder , Maarten M. J. W. Van Herpen , Hendrik R. Stapert
IPC分类号： G01N27/00 , G01N21/64
CPC分类号： G01N21/648 , B01L3/502715 , B01L3/50273 , B01L3/502761 , B01L2200/025 , B01L2300/0654 , B01L2300/0816 , B01L2300/0887 , C12Q1/6837 , G01N21/47 , G01N21/554 , G01N21/658 , G01N2021/95676
摘要： A luminescence sensor, comprising a non-transparent substrate structure (2) having at least one aperture (5) intended to comprise an analyte and a transparent substrate structure (3), which is arranged to or adjacent said first structure (2). The aperture has a smallest lateral dimension, which is smaller than half the effective wavelength of an excitation radiation, such as light at a wavelength of 700 nm, resulting in an effective wavelength in water of about 538 nm. The transparent structure has a trench (4) with a surface portion provided with ligands with an affinity towards a target molecule. The trench results in that a luminophore attached to the target molecule will be positioned at the entrance surface of the aperture, where the excitation energy is largest.
摘要翻译：发光传感器，包括具有至少一个孔（5）的非透明衬底结构（2），所述孔旨在包括被分析物和透明衬底结构（3），所述透明衬底结构（3）布置在所述第一结构（2）上或邻近所述第一结构（2）。孔径具有最小的横向尺寸，其小于激发辐射的有效波长的一半，例如波长为700nm的光，导致在约538nm的水中的有效波长。透明结构具有沟槽（4），其表面部分具有对靶分子具有亲和性的配体。沟槽导致连接到靶分子的发光体将位于孔的入射表面处，其中激发能量最大。

4. 发明授权

US09134244B2 Wiregrid monitor device 有权
标题翻译：铁丝网监控设备
公开(公告)号：US09134244B2
公开(公告)日：2015-09-15
申请号：US12526547
申请日：2008-02-12
申请人： Derk J. W. Klunder , Maarten M. J. W. Van Herpen , Hendrik R. Stapert
发明人： Derk J. W. Klunder , Maarten M. J. W. Van Herpen , Hendrik R. Stapert
IPC分类号： G01N21/64 , B82Y15/00
CPC分类号： G01N21/648 , B82Y15/00 , G01N21/6445 , G01N21/6452
摘要： A device for monitoring radiation emitted by luminophores present in an analyte fluid of a wiregrid biosensor. The monitoring device comprises a non-polarized light source (41) for illuminating the wiregrid biosensor for exciting fluorescent labels arranged in the analyte fluid of said biosensor. A detector (71) detects radiation emitted by the labels after excitation. A polarizing filter (53) is arranged in between the transparent substrate and the detector for suppression of background emission radiation from labels positioned outside apertures in the wiregrid, in the analyte fluid.
摘要翻译：用于监测存在于丝网生物传感器的分析物流体中的发光体发射的辐射的装置。监测装置包括用于照亮丝网生物传感器以激发布置在所述生物传感器的分析物流体中的荧光标记的非偏振光源（41）。检测器（71）检测激励后由标签发射的辐射。偏振滤光器（53）布置在透明基板和检测器之间，用于抑制分析物流体中位于线网中的孔外部的标签的背景辐射辐射。

5. 发明授权

US08649581B2 Colour management for biological samples 有权
标题翻译：生物样品的色彩管理
公开(公告)号：US08649581B2
公开(公告)日：2014-02-11
申请号：US13124693
申请日：2009-10-16
申请人： Maarten M. J. W. Van Herpen , Dirk L. J. Vossen , Sjoerd Stallinga , Bernardus H. W. Hendriks , Erik M. H. P. Van Dijk
发明人： Maarten M. J. W. Van Herpen , Dirk L. J. Vossen , Sjoerd Stallinga , Bernardus H. W. Hendriks , Erik M. H. P. Van Dijk
IPC分类号： G06K9/00
CPC分类号： G06T11/001 , H04N1/62
摘要： A method of determining a color transformation for images of biological material includes preparing a first set of biological test objects using a first preparation method, and preparing a second set of biological test objects using a second preparation method. Each test object in the second set of test objects corresponding to a counterpart test object in the first set of test objects, the test object and its counterpart being of the same biological type of material. For each test object in the first and second set of test objects, the color of the test object is determined thereby generating a first and second set of colors The method further includes generating a conversion table indicating a mapping between the colors in the first set of colors and the corresponding colors in the second set of colors. The first and second preparation methods include first and second staining methods, respectively.
摘要翻译：确定生物材料的图像的颜色变换的方法包括使用第一制备方法制备第一组生物测试对象，并使用第二制备方法制备第二组生物测试对象。第二组测试对象中的每个测试对象对应于第一组测试对象中的对应测试对象，测试对象及其对应物具有相同的生物类型的材料。对于第一和第二组测试对象中的每个测试对象，确定测试对象的颜色，从而生成第一和第二组颜色。该方法还包括生成表示第一组中的颜色之间的颜色之间的映射的转换表颜色和相应的颜色在第二组颜色。第一和第二种制备方法分别包括第一和第二染色方法。

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