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1. 发明申请

US20220252500A1 METHOD FOR STORING PARTICLE ANALYZER AND METHOD FOR MANUFACTURING THE SAME 有权
公开(公告)号：US20220252500A1
公开(公告)日：2022-08-11
申请号：US17624598
申请日：2020-06-24
申请人： NOK CORPORATION
发明人： Yuki MUROTA , Takumi YOSHITOMI , Naohiro FUJISAWA
IPC分类号： G01N15/12 , B01L3/00
摘要： A method is provided for storing a particle analyzer capable of suppressing deterioration of a measurement performance with the lapse of time in a particle analyzer for analyzing particles such as exosomes, pollen, viruses, and bacteria. The particle analyzer has a first storage chamber in which a first liquid is stored, a second storage chamber in which a second liquid containing particles to be analyzed is stored, and a flow path connecting the first storage chamber in fluid communication with the second storage chamber. According to the method, at least a portion of the first storage chamber, the second storage chamber, and the flow path are surface-treated, which includes filling an internal space defined by the first storage chamber, the second storage chamber, and the flow path with a liquid to thereby store the particle analyzer in a state that the surface-treated portion is not in contact with air.

2. 发明申请

US20190255532A1 LIQUID INJECTION ATTACHMENT 审中-公开
公开(公告)号：US20190255532A1
公开(公告)日：2019-08-22
申请号：US16311473
申请日：2017-08-15
申请人： NOK CORPORATION
发明人： Yuki MUROTA
IPC分类号： B01L9/00 , G01N35/10
摘要： A liquid injection attachment formed into a cylindrical body is provided and has, in a rear end portion, an insertion opening for receiving a distal end section of a liquid injecting implement inserted thereinto and a liquid flow outlet in a front end portion. The liquid injection attachment is provided with a lip portion of an annulus shape that bulges on the periphery of the liquid flow outlet, and at least one reduced-diameter portion is formed on an outer cylindrical surface of the cylindrical body.

3. 发明公开

US20230332998A1 PARTICLE ANALYSIS DEVICE AND METHOD FOR PRODUCING SAME 审中-公开
公开(公告)号：US20230332998A1
公开(公告)日：2023-10-19
申请号：US18027839
申请日：2021-08-23
申请人： NOK CORPORATION
发明人： Takumi YOSHITOMI , Yuki MUROTA , Naohiro FUJISAWA , Yuto TOKI
IPC分类号： G01N15/10
CPC分类号： G01N15/1031
摘要： A particle analyzer includes: an upper liquid space for storing first liquid; a lower liquid space for storing second liquid; a connection hole connecting the liquid spaces; a first inlet hole supplying the first liquid to the upper liquid space; a first outlet hole for exhausting air from the upper liquid space; a second inlet hole supplying the second liquid to the lower liquid space; a second outlet hole for exhausting air from the lower liquid space; first and second electrodes respectively applying a potential to the first liquid in the upper liquid space the second liquid in the lower liquid space; first and second lids respectively arranged at the opening of the first outlet hole and at the opening of the second outlet hole, and both lids being formed of a film allowing air to pass but not allowing liquids to pass.

4. 发明申请

US20160332157A1 ATTACHMENT FOR LIQUID INJECTION AND LIQUID INJECTION METHOD 审中-公开
标题翻译：液体注射和液体注射方法的附着
公开(公告)号：US20160332157A1
公开(公告)日：2016-11-17
申请号：US15112340
申请日：2015-04-08
申请人： NOK CORPORATION
发明人： Toru UDA , Goki OKADA , Hiroshi UMEBAYASHI , Yuki MUROTA
IPC分类号： B01L3/02
CPC分类号： B01L3/0275 , B01L3/02 , B01L2200/026 , B01L2200/027 , B01L2200/0689 , B01L2300/0832 , B81B1/00 , G01N1/00 , G01N37/00
摘要： An object of the present invention is to provide a liquid injection attachment enabling a simple liquid injection into a feed port by merely mounting the attachment onto the distal portion of a pipette or a pipette tip when liquid is injected into the feed port, as well as capable of exhibiting an excellent sealing performance without a risk to deform or damage the pipette or the pipette tip, to thereby suppress leakage of liquid during the liquid injection. The object is achieved by a liquid injection attachment removably mounted on a pipette injecting liquid into a feed port through which liquid is introduced or on a pipette tip fitted to the pipette, the attachment including a tubular attachment body having at its distal end a liquid outlet and having at its proximal end an insertion port into which a distal portion of the pipette or of the pipette tip is inserted; and a gasket formed from a rubber-like elastic body disposed around the liquid outlet of the attachment body.
摘要翻译：本发明的目的是提供一种液体注射附件，其能够通过在将液体注射到进料口中时将附件安装到移液管或移液管尖端的远端部分上而简单地注入进料口，以及能够表现出优异的密封性能而不会使移液管或移液管尖端变形或损坏的风险，从而抑制液体注入期间液体的泄漏。该目的是通过可移除地安装在移液管上的液体注射附件来实现的，该移液管将液体注入到通过其引入液体的进料口或装配到移液管的移液管尖端上，该附件包括管状附接体，其在其远端具有液体出口并且在其近端处具有插入口，所述移液管的远端部分或所述移液管末端插入所述插入口中; 以及由设置在附接体的液体出口周围的橡胶状弹性体形成的垫圈。

5. 发明申请

US20230077861A1 PARTICLE SEPARATION DEVICE 有权
公开(公告)号：US20230077861A1
公开(公告)日：2023-03-16
申请号：US17798208
申请日：2021-01-07
申请人： NOK CORPORATION
发明人： Yuki MUROTA , Takumi YOSHITOMI , Naohiro FUJISAWA
IPC分类号： G01N15/12 , G01N1/04 , G01N15/02
摘要： A particle separating device includes at least three liquid chambers adapted to store a liquid therein; at least two liquid passages, each connecting adjacent two of the liquid chambers; an inlet adapted to introduce a liquid in which multiple particles of different sizes are dispersed into one of the liquid chambers; and at least two electrodes disposed inside at least two of the liquid chambers, respectively, the electrodes adapted to apply different electrical potentials to the liquid. The cross-sectional areas of the at least two liquid passages are different from each other.

6. 发明申请

US20220341840A1 METHOD FOR MANUFACTURING PARTICLE ANALYZER AND THE PARTICLE ANALYZER 有权
公开(公告)号：US20220341840A1
公开(公告)日：2022-10-27
申请号：US17641460
申请日：2020-08-28
申请人： NOK CORPORATION
发明人： Takumi YOSHITOMI , Yuki MUROTA , Naohiro FUJISAWA
IPC分类号： G01N15/14 , G01N23/2273
摘要： A method is provided for manufacturing a particle analyzer in which the deterioration of the measurement function is suppressed during the measurement of the particles to be measured. The particle analyzer includes a first storage chamber in which a first liquid is stored, a second storage chamber in which a second liquid containing particles to be analyzed is stored, and a flow path connecting the first storage chamber in fluid communication with the second storage chamber. The method includes a surface modification step of irradiating a surface constituting the flow path with an ultraviolet ray to modify the surface of the flow path.

7. 发明申请

US20230074523A1 PARTICLE ANALYSIS DEVICE 有权
公开(公告)号：US20230074523A1
公开(公告)日：2023-03-09
申请号：US17798187
申请日：2021-02-02
申请人： NOK CORPORATION
发明人： Takumi YOSHITOMI , Yuki MUROTA , Naohiro FUJISAWA , Kosuke SATO , Yuto TOKI
IPC分类号： G01N27/447 , G01N15/10 , B01L3/00
摘要： A particle analysis device includes multiple stacked plates joined together; an upper liquid space adapted to store a first liquid; a lower liquid space adapted to store a second liquid; a connection pore connecting the upper liquid space to the lower liquid space; a first hole extending from the top surface to the upper liquid space, the first liquid flowing through the first hole; and a second hole extending from the top surface to the lower liquid space, the second liquid flowing through the second hole. A first electrode and a second electrode that are sheets are pinched between two of the plates. The first electrode applies an electric potential to the first liquid in the upper liquid space through the first hole, whereas the second electrode applies an electric potential to the second liquid in the lower liquid space through the second hole. The particle analysis device further includes a first electrode-rod-insertion hole extending from the top surface to the first electrode, and a second electrode-rod-insertion hole extending from the top surface to the second electrode. The first electrode and the second electrode are not exposed at any side surface of the particle analysis device.

8. 发明申请

US20220260524A1 PARTICLE ANALYSIS DEVICE 有权
公开(公告)号：US20220260524A1
公开(公告)日：2022-08-18
申请号：US17630675
申请日：2020-05-14
申请人： NOK CORPORATION
发明人： Yuki MUROTA , Takumi YOSHITOMI , Naohiro FUJISAWA
IPC分类号： G01N27/447
摘要： A particle analysis device includes an upper liquid space in which a first liquid is stored, a lower liquid space in which a second liquid is stored, a connection pore connecting the upper liquid space to the lower liquid space, and first to fourth holes. Each of the first to fourth holes has an opening that opens at a top surface of the particle analysis device. The first and second holes extend to the upper liquid space. The third and fourth holes extend to the lower liquid space. A first electrode applies an electric potential to the first liquid in the upper liquid space through the first hole, and a second electrode applies an electric potential to the second liquid in the lower liquid space through the third hole. The opening of at least one of the first hole and the second hole has an area that is greater than the rest of the hole. The opening of at least one of the third hole and the fourth hole has an area that is greater than the rest of the hole.

9. 发明申请

US20190275526A1 LIQUID INJECTION ATTACHMENT AND LIQUID INJECTION DEVICE 审中-公开
公开(公告)号：US20190275526A1
公开(公告)日：2019-09-12
申请号：US16302523
申请日：2017-05-11
申请人： NOK CORPORATION
发明人： Yuki MUROTA , Toru UDA
IPC分类号： B01L3/00 , G01N1/14 , G01N35/10 , B01L3/02
摘要： A liquid injection attachment and device are provided. A cylindrical attachment body includes a through-hole, an insertion opening receiving a distal end of a liquid injecting implement inserted thereinto is included on a rear end side of the through-hole, and an outlet discharging liquid from the liquid injecting implement outside of the attachment body is included on a front end side, a plate shaped annular rib projecting inward in the through-hole leaving the outlet is provided at a front end of the attachment body, an annular receiving face is included on the annular rib and faces the rear end side of the through-hole, the annular receiving face receiving a load from the liquid injecting implement in an axial direction during injection, and an annular lip around the outlet is provided where the load received by the annular receiving face of the annular rib acts in an axial direction.

10. 发明申请

US20170343394A1 COVER STRUCTURE OF TACTILE SENSOR AND TACTILE SENSOR 审中-公开
公开(公告)号：US20170343394A1
公开(公告)日：2017-11-30
申请号：US15518749
申请日：2016-01-29
申请人： NOK Corporation , Nippon Mektron, Ltd.
发明人： Yuki MUROTA , Hiroshi UMEBAYASHI , Toru UDA , Hidekazu YOSHIHARA , Taisuke KIMURA , Keizo TOYAMA
IPC分类号： G01D11/24
摘要： The present invention aims at providing a cover structure of a tactile sensor and a tactile sensor that can secure sufficient adhesion between a sensor body and a covering layer without providing an adhesive layer and have no possibility of causing a sensor to make detection error due to the covering layer formed thereon. A cover structure of a tactile sensor according to the present invention includes a sensor body 2 and a covering layer 3 made of elastic body molded on the sensor body 2. The covering layer 3 includes at least two layers of an outer layer 32 disposed as the outermost layer and an inner layer 31 disposed to come in contact with the sensor body 2 and having a higher adhesiveness and a lower hardness than those of the outer layer 32, and is integrally molded with the sensor body 2 by the cast molding. It is preferable that the sensor body 2 be disposed on the top surface of the base 4, the covering layer 3 cover over the sensor body 2 and the base 4, and the inner layer 31 do not cover the bottom surface of the base 4.

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