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2. 发明申请

US20120061608A1 FUNCTIONAL PARTICLE WITH ROUGH-SURFACED POLYMER COATING 审中-公开
标题翻译：功能颗粒与粗糙表面聚合物涂层
公开(公告)号：US20120061608A1
公开(公告)日：2012-03-15
申请号：US13228286
申请日：2011-09-08
申请人： Masakazu MITSUNAGA , Naoki USUKI , Kenji KOHNO , Hisao KANZAKI
发明人： Masakazu MITSUNAGA , Naoki USUKI , Kenji KOHNO , Hisao KANZAKI
IPC分类号： H01F1/03 , H01F41/02
CPC分类号： H01F1/0054 , A61K49/183
摘要： There is provided a magnetic particle to which a large amount of target substance can bind upon separation, analysis and the like of the target substance, the particle exhibiting a higher rate of the magnetic separation. The magnetic particle to which a target substance can bind, comprising a core particle having magnetism and a polymer coat layer comprising a polymer shell portion in which a rough coating of polymer is provided on a surface of the core particle. This magnetic particle has a roughness due to a surface roughness of the polymer shell portion wherein a specific surface area (m2/g) of the magnetic particle is 1.5 to 500 times a specific surface area (m2/g) of the core particle when the core particle is regarded as a smooth perfect sphere.
摘要翻译：在目标物质的分离，分析等方面，提供大量目标物质可以结合的磁性粒子，该粒子表现出较高的磁分离速度。目标物质可以结合的磁性颗粒，其包含具有磁性的核心颗粒和聚合物涂层，聚合物涂层包含聚合物壳体部分，其中在核心颗粒的表面上提供聚合物的粗糙涂层。该磁性粒子由于聚合物壳体部分的表面粗糙度而具有粗糙度，其中当粒子的比表面积（m 2 / g）为核粒子的比表面积（m 2 / g）时的比表面积（m 2 / g）为1.5〜500倍，核心颗粒被认为是一个光滑的完美球体。

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