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1. 发明授权

US08496964B2 Controlled release micro-capsule for osteogenic action 有权
标题翻译：用于成骨作用的控释微胶囊
公开(公告)号：US08496964B2
公开(公告)日：2013-07-30
申请号：US13203603
申请日：2010-02-26
申请人： Prabhat Ranjan Mishra , Ritu Trivedi , Girish Kumar Gupta , Avinash Kumar , Varsha Gupta , Srikanta Kumar Rath , Kamini Srivastava , Naibedya Chattopadhyay , Anil Kumar Dwivedi
发明人： Prabhat Ranjan Mishra , Ritu Trivedi , Girish Kumar Gupta , Avinash Kumar , Varsha Gupta , Srikanta Kumar Rath , Kamini Srivastava , Naibedya Chattopadhyay , Anil Kumar Dwivedi
IPC分类号： A61K9/52 , A61K9/50 , A61K31/70 , B01J13/00 , B05D3/00 , A01N43/04
CPC分类号： A61K9/1641 , A61K9/1611 , A61K9/1652 , A61K9/1658 , A61K9/5031 , A61K9/5052 , A61K9/5073
摘要： The present invention relates to a microcapsule for controlled release of flavanoid compound and a process for preparation thereof. The microcapsule comprising a core particle consisting of a calcium salt, Pluronic F68 [poly (ethylene oxide-co-polypropylene oxide), block poly oxyethylene-polypropylene block copolymer], loaded with a flavanoid compound, the resulting core particle having a plurality of alternate layers of cationic and anionic polyelectrolytes adsorbed thereon and an outer layer formed by a bile salt, wherein the flavanoid is ranging between 10 to 96% by weight.
摘要翻译：本发明涉及一种用于控制释放类黄酮化合物的微胶囊及其制备方法。所述微胶囊包含由钙盐，Pluronic F68 [聚（环氧乙烷 - 共聚 - 丙烯氧化物），嵌段聚氧乙烯 - 聚丙烯嵌段共聚物]组成的核心颗粒，负载有类黄酮化合物，所得核心颗粒具有多个交替吸附在其上的阳离子和阴离子聚电解质层以及由胆汁盐形成的外层，其中类黄酮的范围在10至96重量％之间。

2. 发明申请

US20110305754A1 CONTROLLED RELEASE MICRO-CAPSULE FOR OSTEOGENIC ACTION 有权
标题翻译：控制释放微胶囊用于卵泡作用
公开(公告)号：US20110305754A1
公开(公告)日：2011-12-15
申请号：US13203603
申请日：2010-02-26
申请人： Prabhat Ranjan Mishra , Ritu Trivedi , Girish Kumar Gupta , Avinash Kumar , Varsha Gupta , Srikanta Kumar Rath , Kamini Srivastava , Naibedya Chattopadhyay , Anil Kumar Dwivedi
发明人： Prabhat Ranjan Mishra , Ritu Trivedi , Girish Kumar Gupta , Avinash Kumar , Varsha Gupta , Srikanta Kumar Rath , Kamini Srivastava , Naibedya Chattopadhyay , Anil Kumar Dwivedi
IPC分类号： A61K9/52 , A61K9/50 , A61P19/10 , A61P19/00 , A61K31/352 , A61K31/7048
CPC分类号： A61K9/1641 , A61K9/1611 , A61K9/1652 , A61K9/1658 , A61K9/5031 , A61K9/5052 , A61K9/5073
摘要： The present invention relates to a microcapsule for controlled release of flavanoid compound and a process for preparation thereof. The microcapsule comprising a core particle consisting of a calcium salt, Pluronic F68 [poly (ethylene oxide-co-polypropylene co-polypropylene oxide), block poly oxyethylene-polypropylene block copolymer], loaded with a flavanoid compound, the resulting core particle having a plurality of alternate layers of cationic and anionic polyelectrolytes adsorbed thereon and an outer layer formed by a bile salt, wherein the flavanoid is ranging between 10 to 96% by weight.
摘要翻译：本发明涉及一种用于控制释放类黄酮化合物的微胶囊及其制备方法。该微胶囊包含由钙盐，Pluronic F68 [聚（环氧乙烷 - 共聚 - 丙烯共聚 - 丙烯氧化物），嵌段聚氧乙烯 - 聚丙烯嵌段共聚物]组成的核心颗粒，负载有类黄酮化合物，所得核心颗粒具有吸附在其上的多个阳离子和阴离子聚电解质的交替层和由胆汁盐形成的外层，其中所述类黄酮的范围在10至96重量％之间。

3. 发明申请

US20140079834A1 BIOACTIVE FRACTIONS AND COMPOUNDS FROM DALBERGIA SISSOO FOR THE PREVENTION OR TREATMENT OF OSTEO-HEALTH RELATED DISORDERS 审中-公开
标题翻译：来自DALBERGIA SISSOO的生物活性成分和化合物用于预防或治疗OSTEO-HEALTH相关疾病
公开(公告)号：US20140079834A1
公开(公告)日：2014-03-20
申请号：US14113561
申请日：2012-04-25
申请人： Rakesh Maurya , Preety Dixit , Ritu Trivedi , Vikram Khedgikar , Jyoti Gautam , Avinash Kumar , Divya Singh , Sheelendra Pratap Singh , (none) Wahajuddin , Girish Kumar Jain , Naibedya Chattopadhyay
发明人： Rakesh Maurya , Preety Dixit , Ritu Trivedi , Vikram Khedgikar , Jyoti Gautam , Avinash Kumar , Divya Singh , Sheelendra Pratap Singh , (none) Wahajuddin , Girish Kumar Jain , Naibedya Chattopadhyay
IPC分类号： A61K31/7048 , A61K31/352 , A61K36/48
CPC分类号： A61K31/7048 , A61K31/352 , A61K36/48 , C07D311/36 , C07H17/07
摘要： The present invention relates to bioactive fractions and compounds from Dalbergia sissoo for the prevention or treatment of osteo-health related disorders. The present invention relates in the field of pharmaceutical composition that provides new plant extracts, their fractions and pure compound isolated from natural sources that are useful for the prevention and/or treatment of various medical indications associated with estrogen dependent or independent diseases or syndromes or disorders preferably in the prevention or treatment of estrogen dependent or independent diseases or syndromes or disorders caused in humans and animals, and achievement of peak bone mass during skeletal growth and health in humans and animals. Particularly the present invention further relates to the processes for the preparation of biologically active extracts, fractions, and isolation of pure compounds, from Dalbergia sissoo plant from the family Fabaceae their pharmaceutically acceptable salts and compositions of the principal aspect of the present invention.
摘要翻译：本发明涉及用于预防或治疗与骨骼健康相关的疾病的生物活性级分和来自枸杞子的化合物。本发明涉及药物组合物领域，其提供新的植物提取物，其级分和从天然来源分离的纯化合物，其可用于预防和/或治疗与雌激素依赖性或独立疾病或综合征或病症相关的各种医学适应症优选地在预防或治疗在人和动物中引起的雌激素依赖性或独立性疾病或综合征或障碍，以及在人和动物的骨骼生长和健康期间达到峰值骨量。特别地，本发明还涉及从家蚕豆科的Dalbergia sissoo植物制备生物活性提取物，级分和分离纯化合物的方法，它们的药学上可接受的盐和本发明主要方面的组合物。

4. 发明授权

US10292994B2 Bioactive fractions and compounds from Dalbergia sissoo for the prevention or treatment of osteo-health related disorders 有权
$Bioactive fractions and compounds from Dalbergia sissoo for the prevention or treatment of osteo-health related disorders$
公开(公告)号：US10292994B2
公开(公告)日：2019-05-21
申请号：US14113561
申请日：2012-04-25
申请人： Rakesh Maurya , Preety Dixit , Ritu Trivedi , Vikram Khedgikar , Jyoti Gautam , Avinash Kumar , Divya Singh , Shelendra Pratap Singh , Wahajuddin , Girish Kumar Jain , Naibedya Chattopadhyay
发明人： Rakesh Maurya , Preety Dixit , Ritu Trivedi , Vikram Khedgikar , Jyoti Gautam , Avinash Kumar , Divya Singh , Shelendra Pratap Singh , Wahajuddin , Girish Kumar Jain , Naibedya Chattopadhyay
IPC分类号： A61K31/7048 , C07D311/36 , C07H17/07 , A61K31/352 , A61K36/48
摘要： The present invention relates to bioactive fractions and compounds from Dalbergia sissoo for the prevention or treatment of osteo-health related disorders. The present invention relates in the field of pharmaceutical composition that provides new plant extracts, their fractions and pure compound isolated from natural sources that are useful for the prevention and/or treatment of various medical indications associated with estrogen dependent or independent diseases or syndromes or disorders preferably in the prevention or treatment of estrogen dependent or independent diseases or syndromes or disorders caused in humans and animals, and achievement of peak bone mass during skeletal growth and health in humans and animals. Particularly the present invention further relates to the processes for the preparation of biologically active extracts, fractions, and isolation of pure compounds, from Dalbergia sissoo plant from the family Fabaceae their pharmaceutically acceptable salts and compositions of the principal aspect of the present invention.

5. 发明申请

US20170100176A1 ANATOMICAL HUMERAL FIXATION SYSTEM AND METHOD 审中-公开
公开(公告)号：US20170100176A1
公开(公告)日：2017-04-13
申请号：US15389592
申请日：2016-12-23
申请人： Avinash Kumar
发明人： Avinash Kumar
IPC分类号： A61B17/86 , A61F2/40 , A61B17/80
CPC分类号： A61F2/40 , A61B17/8009 , A61B17/8019 , A61B17/8042 , A61B17/8047 , A61B17/8061 , A61B17/8085 , A61B17/809 , A61B17/82 , A61B2017/00004 , A61F2002/30034
摘要： An anatomical shoulder fixation system having a stem having a plurality of holes configured to receive bone screws. The stem having compressible suture locking members protruding from the flared head portion configured to receive and lock an elongated member. The plurality of holes configured to have locking mechanisms abutting the holes. The locking mechanisms preventing the bone screw from backing out while also providing the screw the freedom necessary to realign itself during the healing process. In one locking mechanism embodiment, a locking member utilizing a frustoconical split ring configured lock within a retention groove of the bone screw. Another embodiment has a rotating member with a protrusion that locks into a retention groove of the bone screw. An alternative embodiment has a rotating member that rotates over the bone screw utilizing a complimentary angle between the screw head and the protrusion.

6. 发明授权

US09526544B1 Anatomical humeral fixation system and method 有权
标题翻译：解剖肱骨固定系统及方法
公开(公告)号：US09526544B1
公开(公告)日：2016-12-27
申请号：US14218236
申请日：2014-03-18
申请人： Avinash Kumar
发明人： Avinash Kumar
IPC分类号： A61B17/80
CPC分类号： A61B17/8061 , A61B17/8009 , A61B17/8019 , A61B17/8085 , A61B17/809 , A61B2017/00004
摘要： An anatomical shoulder fixation system comprises a lower portion and an upper portion, the lower portion being a separate part and being coupled to the upper portion adjustably. For example, the relative position of the upper portion to the fixation system is capable of rotating and translating with relation to the lower part, accommodating placement on a shoulder even if displacement of the lesser tuberosity and the greater tuberosity due to fracture or dislocation. Examples include a flexible upper portion coupled to a lower portion or a more rigid upper portion joined to a lower portion, and combinations of these. In both examples, screws may be used to fix the lower portion prior to completing the displacement and fixation of the upper portion. For example, the lower portion may provide structures for attaching sutures, suitable for use with a curved needle shaft and suture.
摘要翻译：解剖肩部固定系统包括下部和上部，下部是分离的部分，并且可调整地联接到上部。例如，上部与固定系统的相对位置能够相对于下部旋转和平移，即使由于断裂或脱位而导致较小结节的移位和较大的结节也能容纳位于肩部上的位置。实例包括联接到下部的柔性上部或连接到下部的更刚性的上部，以及这些的组合。在这两个例子中，可以在完成上部的移动和固定之前，使用螺钉来固定下部。例如，下部可以提供用于附接缝线的结构，适合于与弯曲的针轴和缝合线一起使用。

7. 发明授权

US08239654B2 Systems and methods for transferring data in a block-level storage operation 有权
标题翻译：用于在块级存储操作中传输数据的系统和方法
公开(公告)号：US08239654B2
公开(公告)日：2012-08-07
申请号：US13212534
申请日：2011-08-18
申请人： Paul Ignatius , Anand Prahlad , Mahesh Tyagarajan , Avinash Kumar
发明人： Paul Ignatius , Anand Prahlad , Mahesh Tyagarajan , Avinash Kumar
IPC分类号： G06F12/00 , G06F12/16
CPC分类号： G06F3/0613 , G06F3/0653 , G06F3/0656 , G06F3/067 , G06F11/1464
摘要： The invention provides a system and method for storing a copy of data stored in an information store. In one embodiment, a data agent reads one or more blocks containing the data from the information store. The data agent maps the one or more blocks to provide a mapping of the blocks, and transmits the one or more blocks and mapping to a media agent for a storage device. The media agent stores the one or more blocks in the storage device according to the mapping.
摘要翻译：本发明提供一种用于存储存储在信息存储器中的数据的副本的系统和方法。在一个实施例中，数据代理从信息存储器读取包含数据的一个或多个块。数据代理映射一个或多个块以提供块的映射，并发送一个或多个块并映射到存储设备的媒体代理。媒体代理根据映射将一个或多个块存储在存储设备中。

8. 发明申请

US20120179886A1 SNAPSHOT STORAGE AND MANAGEMENT SYSTEM WITH INDEXING AND USER INTERFACE 有权
标题翻译： SNAPSHOT存储和管理系统与索引和用户界面
公开(公告)号：US20120179886A1
公开(公告)日：2012-07-12
申请号：US13424461
申请日：2012-03-20
申请人： Anand Prahlad , Andreas May , Norman R. Lunde , Lixin Zhou , Avinash Kumar , David Ngo
发明人： Anand Prahlad , Andreas May , Norman R. Lunde , Lixin Zhou , Avinash Kumar , David Ngo
IPC分类号： G06F12/16
CPC分类号： G06F3/065 , G06F3/0601 , G06F3/0619 , G06F3/067 , G06F11/1448 , G06F11/1451 , G06F11/1456 , G06F11/1469 , G06F2003/0697 , G06F2201/84 , Y10S707/99953 , Y10S707/99955
摘要： A system and method of managing stored data in a storage management system. The storage management system includes a storage manager, a media agent connected to the storage manager, and a primary volume connected to the media agent. Multiple snapshots are taken of the primary volume. The snapshots are indexed by associating respective information with the snapshot. The indexed snapshots are copied to a recovery volume. In this way, browsing features are enabled for the user. The user may view the snapshots in a hierarchical format, and may even view snapshot data in association with the corresponding application. The resultant recovery volume may be used to replace a primary volume.
摘要翻译：一种在存储管理系统中管理存储数据的系统和方法。存储管理系统包括存储管理器，连接到存储管理器的媒体代理以及连接到媒体代理的主卷。拍摄主卷的多张快照。通过将各个信息与快照相关联来对快照进行索引。索引的快照将复制到恢复卷。以这种方式，用户可以启用浏览功能。用户可以以分层格式查看快照，甚至可以与相应的应用相关联地查看快照数据。所得到的恢复卷可以用于替换主卷。

9. 发明申请

US20100042804A1 SYSTEMS AND METHODS FOR TRANSFERRING DATA IN A BLOCK-LEVEL STORAGE OPERATION 有权
标题翻译：用于在块级存储操作中传输数据的系统和方法
公开(公告)号：US20100042804A1
公开(公告)日：2010-02-18
申请号：US12546087
申请日：2009-08-24
申请人： Paul Ignatius , Anand Prahlad , Mahesh Tyagarajan , Avinash Kumar
发明人： Paul Ignatius , Anand Prahlad , Mahesh Tyagarajan , Avinash Kumar
IPC分类号： G06F12/10
CPC分类号： G06F3/0613 , G06F3/0653 , G06F3/0656 , G06F3/067 , G06F11/1464
摘要： The invention provides a system and method for storing a copy of data stored in an information store. In one embodiment, a data agent reads one or more blocks containing the data from the information store. The data agent maps the one or more blocks to provide a mapping of the blocks, and transmits the one or more blocks and mapping to a media agent for a storage device. The media agent stores the one or more blocks in the storage device according to the mapping.
摘要翻译：本发明提供一种用于存储存储在信息存储器中的数据的副本的系统和方法。在一个实施例中，数据代理从信息存储器读取包含数据的一个或多个块。数据代理映射一个或多个块以提供块的映射，并发送一个或多个块并映射到存储设备的媒体代理。媒体代理根据映射将一个或多个块存储在存储设备中。

10. 发明申请

US20050268068A1 Method and system for transferring data in a storage operation 有权
标题翻译：用于在存储操作中传送数据的方法和系统
公开(公告)号：US20050268068A1
公开(公告)日：2005-12-01
申请号：US11029211
申请日：2005-01-03
申请人： Paul Ignatius , Anand Prahlad , Mahesh Tyagarajan , Avinash Kumar
发明人： Paul Ignatius , Anand Prahlad , Mahesh Tyagarajan , Avinash Kumar
IPC分类号： G06F3/06 , G06F11/14 , G06F13/00
CPC分类号： G06F3/0613 , G06F3/0653 , G06F3/0656 , G06F3/067 , G06F11/1464
摘要： The invention provides a system and method for storing a copy of data stored in an information store. In one embodiment, a data agent reads one or more blocks containing the data from the information store. The data agent maps the one or more blocks to provide a mapping of the blocks, and transmits the one or more blocks and mapping to a media agent for a storage device. The media agent stores the one or more blocks in the storage device according to the mapping.
摘要翻译：本发明提供一种用于存储存储在信息存储器中的数据的副本的系统和方法。在一个实施例中，数据代理从信息存储器读取包含数据的一个或多个块。数据代理映射一个或多个块以提供块的映射，并发送一个或多个块并映射到存储设备的媒体代理。媒体代理根据映射将一个或多个块存储在存储设备中。

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