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    • 1. 发明申请
    • Medication Delivery Device
    • 药物输送装置
    • US20130310762A1
    • 2013-11-21
    • US13943036
    • 2013-07-16
    • Sanofi-Aventis Deutschland GmbH
    • Christopher James SmithMichael HealdStephen David ButlerMark Philip Horlock
    • A61M5/315
    • A61M5/31585
    • A medication delivery device is provided which is switchable between an operational state and a resetting state and which comprises a housing having a proximal end and a distal end, a piston rod being moveable in a distal direction with respect to the housing for medication delivery, a conversion element adapted to at least partially convert a rotational movement of the piston rod into an axial movement of the piston rod, coupling means prevented from rotational movement with respect to the housing and adapted to engage with the conversion element in the operational state, a drive assembly comprising at least two drive assembly members and adapted for moving the piston rod in the distal direction, and a resilient member adapted to provide a force on the drive assembly for engagement of the drive assembly members. In the operational state of the device the coupling means is engaged with the conversion element, the conversion element thereby being prevented from rotation with respect to the housing. In the resetting state of the device the coupling means is disengaged from the conversion element under force of the resilient member, the conversion element thereby being allowed to rotate with respect to the housing and thereby allowing a resetting of the device.
    • 提供了一种药物输送装置,其可在操作状态和复位状态之间切换,并且其包括具有近端和远端的壳体,活塞杆可相对于用于药物输送的壳体在远端方向上移动, 转换元件,适于至少部分地将活塞杆的旋转运动转换成活塞杆的轴向运动,联接装置防止相对于壳体的旋转运动并且适于在操作状态下与转换元件接合,驱动 组件,其包括至少两个驱动组件构件并且适于沿远端方向移动活塞杆;以及弹性构件,其适于在驱动组件上提供力以接合驱动组件构件。 在装置的操作状态下,联接装置与转换元件接合,因此可以防止转换元件相对于壳体旋转。 在装置的复位状态下,联接装置在弹性构件的力作用下与转换元件分离,因此转换元件允许相对于壳体旋转,从而允许装置的复位。
    • 3. 发明授权
    • Medication delivery device
    • 药物输送装置
    • US08834430B2
    • 2014-09-16
    • US13943036
    • 2013-07-16
    • Sanofi-Aventis Deutschland GmbH
    • Christopher James SmithMichael HealdStephen David ButlerMark Philip Horlock
    • A61M5/315
    • A61M5/31585
    • A medication delivery device is provided which is switchable between an operational state and a resetting state and which comprises a housing having a proximal end and a distal end, a piston rod being moveable in a distal direction with respect to the housing for medication delivery, a conversion element adapted to at least partially convert a rotational movement of the piston rod into an axial movement of the piston rod, coupling means prevented from rotational movement with respect to the housing and adapted to engage with the conversion element in the operational state, a drive assembly comprising at least two drive assembly members and adapted for moving the piston rod in the distal direction, and a resilient member adapted to provide a force on the drive assembly for engagement of the drive assembly members. In the operational state of the device the coupling means is engaged with the conversion element, the conversion element thereby being prevented from rotation with respect to the housing. In the resetting state of the device the coupling means is disengaged from the conversion element under force of the resilient member, the conversion element thereby being allowed to rotate with respect to the housing and thereby allowing a resetting of the device.
    • 提供了一种药物输送装置,其可在操作状态和复位状态之间切换,并且其包括具有近端和远端的壳体,活塞杆可相对于用于药物输送的壳体在远端方向上移动, 转换元件,适于至少部分地将活塞杆的旋转运动转换成活塞杆的轴向运动,联接装置防止相对于壳体的旋转运动并且适于在操作状态下与转换元件接合,驱动 组件,其包括至少两个驱动组件构件并且适于沿远端方向移动活塞杆;以及弹性构件,其适于在驱动组件上提供力以接合驱动组件构件。 在装置的操作状态下,联接装置与转换元件接合,因此可以防止转换元件相对于壳体旋转。 在装置的复位状态下,联接装置在弹性构件的力作用下与转换元件分离,因此转换元件允许相对于壳体旋转,从而允许装置的复位。
    • 4. 发明授权
    • Drive mechanism for a drug delivery device and drug delivery device
    • 用于药物递送装置和药物递送装置的驱动机构
    • US08961473B2
    • 2015-02-24
    • US13947259
    • 2013-07-22
    • Sanofi-Aventis Deutschland GmbH
    • Michael Heald
    • A61M5/00A61M5/315
    • A61M5/31545A61M5/3155A61M5/31583
    • A drive mechanism for a drug delivery device comprises a housing having a proximal end and a distal end and a piston rod, which is adapted to be displaced in a distal direction with respect to the housing when dispensing a drug dose. A drive member is adapted to be rotated when dispensing the drug dose, wherein the drive mechanism is configured to convert rotational movement of the drive member into a movement of the piston rod in the distal direction with respect to the housing. A stop member is adapted to prevent a rotational movement of the drive member with respect to the housing when setting a drug dose. The drive member comprises a drive portion being coupled to the piston rod and a first coupling portion which couples the drive portion and the stop member, wherein the drive mechanism is configured to be switchable between a set and dispense mode of operation and a reset mode of operation, and wherein, in the set and dispense mode, said first coupling portion is bi-directionally coupled to the drive portion for setting and dispensing the drug dose, and wherein, in the reset mode, said first coupling portion is decoupled from the drive portion to allow a reset operation to be performed for the drive mechanism.
    • 用于药物输送装置的驱动机构包括具有近端和远端的壳体和活塞杆,其适于当分配药物剂量时相对于壳体在远侧方向上移位。 驱动构件适于在分配药物剂量时旋转,其中驱动机构构造成将驱动构件的旋转运动转换成活塞杆相对于壳体在远侧方向上的移动。 止挡构件适于在设定药物剂量时防止驱动构件相对于壳体的旋转运动。 驱动构件包括联接到活塞杆的驱动部分和联接驱动部分和止动构件的第一联接部分,其中驱动机构构造成可以在设定和分配操作模式与复位模式之间切换 并且其中,在所述设定和分配模式中,所述第一联接部分双向耦合到所述驱动部分以设置和分配所述药物剂量,并且其中,在所述复位模式中,所述第一联接部分与所述驱动器分离 部分,以允许对驱动机构执行复位操作。
    • 6. 发明申请
    • DRIVE MECHANISM FOR A DRUG DELIVERY DEVICE AND DRUG DELIVERY DEVICE
    • 用于药物递送装置和药物递送装置的驱动机构
    • US20130317452A1
    • 2013-11-28
    • US13947259
    • 2013-07-22
    • Sanofi-Aventis Deutschland GmbH
    • Michael Heald
    • A61M5/315
    • A61M5/31545A61M5/3155A61M5/31583
    • A drive mechanism for a drug delivery device comprises a housing having a proximal end and a distal end and a piston rod, which is adapted to be displaced in a distal direction with respect to the housing when dispensing a drug dose. A drive member is adapted to be rotated when dispensing the drug dose, wherein the drive mechanism is configured to convert rotational movement of the drive member into a movement of the piston rod in the distal direction with respect to the housing. A stop member is adapted to prevent a rotational movement of the drive member with respect to the housing when setting a drug dose. The drive member comprises a drive portion being coupled to the piston rod and a first coupling portion which couples the drive portion and the stop member, wherein the drive mechanism is configured to be switchable between a set and dispense mode of operation and a reset mode of operation, and wherein, in the set and dispense mode, said first coupling portion is bi-directionally coupled to the drive portion for setting and dispensing the drug dose, and wherein, in the reset mode, said first coupling portion is decoupled from the drive portion to allow a reset operation to be performed for the drive mechanism.
    • 用于药物输送装置的驱动机构包括具有近端和远端的壳体和活塞杆,其适于当分配药物剂量时相对于壳体在远侧方向上移位。 驱动构件适于在分配药物剂量时旋转,其中驱动机构构造成将驱动构件的旋转运动转换成活塞杆相对于壳体在远侧方向上的移动。 止挡构件适于在设定药物剂量时防止驱动构件相对于壳体的旋转运动。 驱动构件包括联接到活塞杆的驱动部分和联接驱动部分和止动构件的第一联接部分,其中驱动机构构造成可以在设定和分配操作模式与复位模式之间切换 并且其中,在所述设定和分配模式中,所述第一联接部分双向耦合到所述驱动部分以设置和分配所述药物剂量,并且其中,在所述复位模式中,所述第一联接部分与所述驱动器分离 部分,以允许对驱动机构执行复位操作。
    • 7. 发明申请
    • DRIVE MECHANISM FOR A DRUG DELIVERY DEVICE
    • 用于药物递送装置的驱动机构
    • US20130324936A1
    • 2013-12-05
    • US13952915
    • 2013-07-29
    • Sanofi-Aventis Deutschland GmbH
    • Michael HealdStephen David ButlerMark Philip Horlock
    • A61M5/315
    • A61M5/31543A61M5/315
    • A drive mechanism for a drug delivery device which can be switched between a normal operation mode and a reset mode comprises of a housing having a proximal end and a distal end, a piston rod which is adapted to be displaced in a distal direction with respect to the housing for delivering a dose in a normal operation mode of the drive mechanism, and which is adapted to be displaced in the proximal direction with respect to the housing in a reset mode of the drive mechanism, and a drive member which is rotationally moveable in a rotation direction with respect to the housing, wherein, in the normal operation mode, the drive member is coupled with the piston rod so that rotational movement of the drive member in the rotation direction with respect to the housing is converted into movement of the piston rod in the distal direction with respect to the housing, and wherein, in the reset mode, the piston rod is decoupled from the drive member.
    • 用于可在正常操作模式和复位模式之间切换的药物输送装置的驱动机构包括具有近端和远端的壳体,活塞杆适于相对于远端方向移动 所述壳体用于以所述驱动机构的正常操作模式递送剂量,并且适于在所述驱动机构的复位模式中相对于所述壳体在所述近端方向上移位;以及驱动构件,其可旋转地移动 相对于壳体的旋转方向,其中,在正常操作模式中,驱动构件与活塞杆联接,使得驱动构件相对于壳体沿旋转方向的旋转运动转换为活塞的运动 杆相对于壳体在远端方向上,并且其中,在复位模式下,活塞杆与驱动构件分离。