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1. 发明授权

US10780231B2 Drive mechanism for a drug delivery device and drug delivery device 有权
公开(公告)号：US10780231B2
公开(公告)日：2020-09-22
申请号：US14423736
申请日：2013-09-09
申请人： SANOFI-AVENTIS DEUTSCHLAND GMBH
发明人： Stephen David Butler , Mark Philip Horlock
IPC分类号： A61M5/315
摘要： The present invention concerns a drive mechanism for a drug delivery device comprising a housing having a longitudinal axis, a first feedback element which is movable along the longitudinal axis relative to the housing and a second feedback element, wherein the first feedback element and the second feedback element are adapted to interact with each other thereby providing at least one of tactile and audible feedback during at least one of a dose setting and dose dispensing operation of the drive mechanism. Moreover a drug delivery device incorporating such a drive mechanism is disclosed.

2. 发明申请

US20140303562A1 OPERATION AID FOR A MEDICATION DELIVERY DEVICE AND MEDICATION DELIVERY DEVICE COMPRISING AN OPERATION AID 审中-公开
标题翻译：用于药物输送装置的操作辅助装置和包含操作援助的药物递送装置
公开(公告)号：US20140303562A1
公开(公告)日：2014-10-09
申请号：US14359352
申请日：2012-11-26
申请人： SANOFI-AVENTIS DEUTSCHLAND GMBH
发明人： Stephan Riedel , Stefan Wendland , Stephen David Butler , Mark Phillip Horlock
IPC分类号： A61M5/20
CPC分类号： A61M5/2033 , A61M5/20 , A61M5/24 , A61M2005/2006 , A61M2205/586
摘要： The present disclosure relates to an operation aid for a medication delivery device, which is configured to alleviate the operation of an actuator of the medication delivery device. Furthermore, a system comprising a medication delivery device and an operation aid is disclosed.
摘要翻译：本公开涉及一种用于药物输送装置的操作辅助装置，其被配置为减轻药物输送装置的致动器的操作。此外，公开了包括药物输送装置和操作辅助装置的系统。

3. 发明申请

US20130310762A1 Medication Delivery Device 有权
标题翻译：药物输送装置
公开(公告)号：US20130310762A1
公开(公告)日：2013-11-21
申请号：US13943036
申请日：2013-07-16
申请人： Sanofi-Aventis Deutschland GmbH
发明人： Christopher James Smith , Michael Heald , Stephen David Butler , Mark Philip Horlock
IPC分类号： A61M5/315
CPC分类号： A61M5/31585
摘要： A medication delivery device is provided which is switchable between an operational state and a resetting state and which comprises a housing having a proximal end and a distal end, a piston rod being moveable in a distal direction with respect to the housing for medication delivery, a conversion element adapted to at least partially convert a rotational movement of the piston rod into an axial movement of the piston rod, coupling means prevented from rotational movement with respect to the housing and adapted to engage with the conversion element in the operational state, a drive assembly comprising at least two drive assembly members and adapted for moving the piston rod in the distal direction, and a resilient member adapted to provide a force on the drive assembly for engagement of the drive assembly members. In the operational state of the device the coupling means is engaged with the conversion element, the conversion element thereby being prevented from rotation with respect to the housing. In the resetting state of the device the coupling means is disengaged from the conversion element under force of the resilient member, the conversion element thereby being allowed to rotate with respect to the housing and thereby allowing a resetting of the device.
摘要翻译：提供了一种药物输送装置，其可在操作状态和复位状态之间切换，并且其包括具有近端和远端的壳体，活塞杆可相对于用于药物输送的壳体在远端方向上移动，转换元件，适于至少部分地将活塞杆的旋转运动转换成活塞杆的轴向运动，联接装置防止相对于壳体的旋转运动并且适于在操作状态下与转换元件接合，驱动组件，其包括至少两个驱动组件构件并且适于沿远端方向移动活塞杆;以及弹性构件，其适于在驱动组件上提供力以接合驱动组件构件。在装置的操作状态下，联接装置与转换元件接合，因此可以防止转换元件相对于壳体旋转。在装置的复位状态下，联接装置在弹性构件的力作用下与转换元件分离，因此转换元件允许相对于壳体旋转，从而允许装置的复位。

4. 发明申请

US20190009033A1 Bearing for a Piston Rod Body for a Drug Delivery Device, a Piston Rod Arrangement and a Piston Rod Body 审中-公开
公开(公告)号：US20190009033A1
公开(公告)日：2019-01-10
申请号：US16102149
申请日：2018-08-13
申请人： Sanofi-Aventis Deutschland GMBH
发明人： Stephen David Butler , Mark Philip Horlock
IPC分类号： A61M5/315
摘要： The present disclosure concerns a bearing for a piston rod body for a drug delivery device. The bearing has an axis and comprises a first and a second surface which are spaced apart in the direction of the axis and a third surface, wherein the third surface connects the first and the second surface, wherein an opening is provided in each of the first and the third surface, and wherein the opening in the first surface is connected to the opening in the third surface. Further, the present disclosure concerns a piston rod body and a piston rod arrangement comprising said bearing and the piston rod body.

5. 发明授权

US09849250B2 Drive assembly, drive component and drug delivery device 有权
公开(公告)号：US09849250B2
公开(公告)日：2017-12-26
申请号：US15244056
申请日：2016-08-23
申请人： Sanofi-Aventis Deutschland GmbH
发明人： Christopher James Smith , Stephen David Butler , Mark Philip Horlock
IPC分类号： A61M5/315 , A61M5/142 , F16H19/02
CPC分类号： A61M5/31551 , A61M5/142 , A61M5/31536 , A61M5/31555 , A61M5/31585 , A61M2205/581 , A61M2205/582 , F16H19/02 , Y10T74/18568
摘要： A drive assembly for a drug delivery device comprises a rotation member being configured to be rotated in a first direction during setting of a dose of a drug and to be rotated in a second direction during delivery of the dose, a drive component being configured to follow rotational movement of the rotation member in the second direction during delivery of the dose and a stop member being configured to prevent rotational movement of the drive component in the first direction. The drive component comprises a first drive part and a second drive part, coupled to each other such that relative rotational movement of the first and second drive parts is prevented and relative axial movement is permitted.

6. 发明授权

US09597459B2 Drive mechanism for a drug delivery device 有权
公开(公告)号：US09597459B2
公开(公告)日：2017-03-21
申请号：US13952915
申请日：2013-07-29
申请人： Sanofi-Aventis Deutschland GmbH
发明人： Michael Heald , Stephen David Butler , Mark Philip Horlock
IPC分类号： A61M5/315
CPC分类号： A61M5/31543 , A61M5/315
摘要： A drive mechanism for a drug delivery device is presented that can be switched between a normal operation mode and a reset mode. A piston rod is displaced in a distal direction to deliver a dose in a normal operation mode and is displaced in the proximal direction in a reset mode. The drive mechanism also has a drive member that is rotationally moveable with respect to the housing, wherein in the normal operation mode, the drive member is coupled with the piston rod so that rotational movement of the drive member in the rotation direction with respect to the housing is converted into movement of the piston rod in the distal direction with respect to the housing, and wherein, in the reset mode, the piston rod is decoupled from the drive member.

7. 发明申请

US20150238699A1 DRIVE MECHANISM FOR A DRUG DELIVERY DEVICE AND DRUG DELIVERY DEVICE 审中-公开
标题翻译：用于药物递送装置和药物递送装置的驱动机构
公开(公告)号：US20150238699A1
公开(公告)日：2015-08-27
申请号：US14423736
申请日：2013-09-09
申请人： SANOFI-AVENTIS DEUTSCHLAND GMBH
发明人： Stephen David Butler , Mark Philip Horlock
IPC分类号： A61M5/315
摘要： The present invention concerns a drive mechanism for a drug delivery device comprising a housing having a longitudinal axis, a first feedback element which is movable along the longitudinal axis relative to the housing and a second feedback element, wherein the first feedback element and the second feedback element are adapted to interact with each other thereby providing at least one of tactile and audible feedback during at least one of a dose setting and dose dispensing operation of the drive mechanism. Moreover a drug delivery device incorporating such a drive mechanism is disclosed.
摘要翻译：本发明涉及用于药物输送装置的驱动机构，其包括具有纵向轴线的壳体，可相对于壳体沿着纵向轴线移动的第一反馈元件和第二反馈元件，其中第一反馈元件和第二反馈元件元件适于彼此相互作用，从而在驱动机构的剂量设定和剂量分配操作中的至少一个期间提供触觉和可听见的反馈中的至少一个。此外，公开了一种结合了这种驱动机构的药物输送装置。

8. 发明授权

US10596325B2 Pen-type drug injection device with iris style quick coupling for piston rod resetting 有权
公开(公告)号：US10596325B2
公开(公告)日：2020-03-24
申请号：US15571605
申请日：2016-05-09
申请人： SANOFI-AVENTIS DEUTSCHLAND GMBH
发明人： Stephen David Butler , Mark Philip Horlock
IPC分类号： A61M5/315 , A61M5/24
摘要： A pen-type drug injection device is disclosed which comprises a housing having a longitudinal axis, a threaded piston rod, a guide member for guiding the piston rod in a drug dispense operation, and a cartridge holder for receiving a cartridge, wherein the cartridge holder is detachable from the housing and wherein the guide member comprises an iris type aperture defined by a plurality of threaded pivotable segments. The drug delivery device is configured such that the aperture increases in diameter when the cartridge holder is being detached from the housing, such that the piston rod is free of the threaded engagement with the guide member and can be reset or pushed back to its initial position, and decreases in diameter when the cartridge holder is attached, such that the threads on segments reengage the piston rod.

9. 发明授权

US09700679B2 Drive mechanism for a drug delivery device and drug delivery device 有权
公开(公告)号：US09700679B2
公开(公告)日：2017-07-11
申请号：US14401942
申请日：2013-05-28
申请人： SANOFI-AVENTIS DEUTSCHLAND GMBH
发明人： Stephen David Butler , Mark Philip Horlock
IPC分类号： A61M5/315 , A61M5/24
CPC分类号： A61M5/31595 , A61M5/24 , A61M5/31501 , A61M5/31543 , A61M5/3155 , A61M5/31551 , A61M5/31585
摘要： The drive mechanism for a drug delivery device comprises a piston rod, which is displaced in a distal direction for a delivery of a dose and in a proximal direction for a reset, and a resilient member, which acts on the piston rod during a reset and tends to restrict the movement of the piston rod in the proximal direction. The resilient member may be a biasing member provided for an automatic reset, a compression spring entering the piston rod or a torsion spring provided to generate a rotation. The drug delivery device is provided with such a drive mechanism.

10. 发明申请

US20170000951A1 Drive Assembly, Drive Component and Drug Delivery Device 审中-公开
标题翻译：驱动组件，驱动组件和药物输送装置
公开(公告)号：US20170000951A1
公开(公告)日：2017-01-05
申请号：US15244056
申请日：2016-08-23
申请人： Sanofi-Aventis Deutschland GmbH
发明人： Christopher James Smith , Stephen David Butler , Mark Philip Horlock
IPC分类号： A61M5/315
CPC分类号： A61M5/31551 , A61M5/142 , A61M5/31536 , A61M5/31555 , A61M5/31585 , A61M2205/581 , A61M2205/582 , F16H19/02 , Y10T74/18568
摘要： A drive assembly (70) for a drug delivery device (1) comprises a rotation member (21) being configured to be rotated in a first direction (44) during setting of a dose of a drug and to be rotated in a second direction (47) during delivery of the dose, a drive component (20) being configured to follow rotational movement of the rotation member (21) in the second direction (47) during delivery of the dose and a stop member (26) being configured to prevent rotational movement of the drive component (20) in the first direction (44). The drive component (20) comprises a first drive part (71) and a second drive part (72), coupled to each other such that relative rotational movement of the first and second drive parts (71, 72) is prevented and relative axial movement is permitted.
摘要翻译：用于药物输送装置（1）的驱动组件（70）包括旋转构件（21），其构造成在药物剂量的设定期间沿第一方向（44）旋转并沿第二方向旋转在剂量输送期间，驱动部件（20）构造成在剂量输送期间跟随旋转部件（21）在第二方向（47）上的旋转运动，而止动部件（26）构造成防止驱动部件（20）沿第一方向（44）的旋转运动。驱动部件（20）包括彼此联接的第一驱动部分（71）和第二驱动部分（72），使得防止第一和第二驱动部分（71,72）的相对旋转运动并且相对轴向运动是允许的。

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