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    • 1. 发明授权
    • Visual cardiomyocyte analysis
    • 视觉心肌细胞分析
    • US09582894B2
    • 2017-02-28
    • US14651532
    • 2013-09-19
    • TAMPEREEN YLIOPISTOTTY-saatio
    • Katriina Aalto-SetalaAnna KiviahoJari HyttinenAntti AholaMarkus HonkanenHenna Venalainen
    • G06K9/00G06T7/20G01N33/483G06T7/00
    • G06T7/246G01N33/4833G06T7/0016G06T7/11G06T7/223G06T2207/10016G06T2207/10056G06T2207/20021G06T2207/30024G06T2207/30048
    • Method for analyzing the beating of a derived human cardiomyocyte (CM) includes obtaining the derived human CM, capturing a sequence of images depicting the derived human CM over an analysis period, and determining at least one signal descriptive of the beating of the derived human CM during the analysis period on basis of the sequence of captured images. Apparatuses, and a computer program for analyzing the beating of a derived human CM are configured to obtain: the sequence of images depicting the derived human CM over an analysis period, information indicative of the region of the images depicting the derived human CM, information indicative of two or more sub-regions within the region, and determine two or more signals characterizing the displacement within the region of images depicting the derived human cardiomyocyte, each signal characterizing the extent of displacement within a respective sub-region of the region as a function of time.
    • 用于分析衍生的人心肌细胞(CM)的跳动的方法包括:获得所导出的人CM,在分析周期内捕获描绘所导出的人CM的图像序列,以及确定描述所导出的人CM的跳动的至少一个信号 在分析期间基于捕获图像的顺序。 用于分析导出的人CM的跳动的装置和计算机程序被配置为获得:在分析周期中描绘所导出的人CM的图像序列,指示描绘所导出的人CM的图像的区域的信息,指示的信息 的两个或更多个子区域,并且确定表征所述导出的人类心肌细胞的图像区域内的位移的两个或更多个信号,每个信号表征该区域的相应子区域内的位移程度作为函数 的时间。