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1. 发明公开

US20240277948A1 ELECTRONIC MODULE FOR MEDICAL DEVICE 审中-公开
公开(公告)号：US20240277948A1
公开(公告)日：2024-08-22
申请号：US18645057
申请日：2024-04-24
申请人： Norton (Waterford) Limited
发明人： James Roche , Enrique Calderon Oliveras
IPC分类号： A61M15/00 , G16H20/13 , G16H40/63 , H05K1/18
CPC分类号： A61M15/0001 , G16H20/13 , G16H40/63 , H05K1/181 , A61M2205/8206 , H05K2201/10037 , H05K2201/10628
摘要： An electronic module for a medical device such as an inhaler is disclosed, the electronic module comprising a printed circuit board, and a damper configured to dampen energy transfer to and/or from a battery when a battery is connected to the electronic module and the electronic module is exposed to mechanical shock.

2. 发明授权

US11957832B2 Breath actuated inhaler 有权
公开(公告)号：US11957832B2
公开(公告)日：2024-04-16
申请号：US17062185
申请日：2020-10-02
申请人： Norton (Waterford) Limited
发明人： Declan Walsh , Paul Prendergast , Daniel Buck , Trevor Kent , Niall Thompson
IPC分类号： A61M15/00 , A61K31/46 , A61K31/575 , A61M16/00 , A61M16/20 , A61M39/24 , B29C45/37
CPC分类号： A61M15/0095 , A61K31/46 , A61K31/575 , A61M15/009 , A61M16/208 , A61M39/24 , A61M15/0026 , A61M15/0068 , A61M2016/0015 , A61M2039/242 , A61M2039/244 , A61M2202/064 , A61M2207/10 , B29C45/37 , B29K2995/0072 , B29K2995/0073
摘要： A breath actuated metered dose inhaler may comprise a canister fire system configured to fire a medicament containing canister in response to patient inhalation. The canister fire system may comprise a pneumatic force holding unit and having a rest configuration in which a metering valve of the canister is in a refill configuration; a prepared configuration in which a canister actuation force is retained by the pneumatic force holding unit and the canister fire system is actuatable by patient inhalation induced airflow; and a fire configuration in which the metering valve is in a dose delivery position. When in the prepared configuration, the force retained by the pneumatic force holding unit may be reduced by less than about 6% over a period of 5 minutes, preferably less than about 3% over a period of 5 minutes.

3. 发明公开

US20230381432A1 DRY POWDER MEDICAMENT INHALER 审中-公开
公开(公告)号：US20230381432A1
公开(公告)日：2023-11-30
申请号：US18450030
申请日：2023-08-15
申请人： NORTON (WATERFORD) LIMITED
发明人： Peter John CROWLEY , Jan Geert HAZENBERG , Daniel BUCK , Josh GOTTESMAN
IPC分类号： A61M15/00
CPC分类号： A61M15/0051 , A61M15/0003 , A61M15/0043 , A61M2202/064
摘要： Disclosed is a dry powder inhaler for delivering medicament from at least one blister pack, each blister pack having a plurality of spaced-apart blister pockets containing doses of the medicament. The inhaler comprises: a housing for accommodating unused and used portions of the at least one blister pack together with a dispensing mechanism for simultaneously opening at least two blister pockets at a time; and a manifold component through which air can be drawn in use of the inhaler. The manifold component comprises: first and second air inlet openings for receiving external air a first air outlet opening for providing the external air to a first opened blister pocket and a first medicament inlet opening for receiving air-entrained medicament from the first opened blister pocket, the first air outlet opening and the first medicament inlet opening being arranged side-by-side to enable simultaneous communication with the first opened blister pocket; a second air outlet opening for providing the external air to a second opened blister pocket and a second medicament inlet opening for receiving air-entrained medicament from the second opened blister pocket, the second air outlet opening and the second medicament inlet opening being arranged side-by-side to enable simultaneous communication with the second opened blister pocket; and a medicament outlet opening for delivery of the air-entrained medicament from the first and second opened blister pockets to the user, the first and second medicament inlet openings being fluidly connected to the medicament outlet opening by a medicament delivery conduit formed in the manifold component. The first and second air inlet openings are fluidly connected to the first and second air outlet openings by respective first and second air conduits in the manifold component, wherein the air conduits are separately provided so that the external air from each of the first and second air inlet openings does not mix with the external air from the other of the first and second air inlet openings before reaching the first and second opened blister pockets.

4. 发明授权

US11771851B2 Testing method for a dry powder inhaler 有权
公开(公告)号：US11771851B2
公开(公告)日：2023-10-03
申请号：US17337325
申请日：2021-06-02
申请人： NORTON (WATERFORD) LIMITED
发明人： Denis Henry O'Sullivan , Daniel R Buck
IPC分类号： A61M15/00 , A61M16/14 , G01N15/06 , G01N15/00
CPC分类号： A61M15/0008 , A61M15/0001 , A61M15/0086 , A61M15/0091 , A61M16/14 , G01N15/06 , A61M2202/064 , G01N2015/0046 , G01N2015/0693
摘要： The invention provides a method of testing an inhaler based on performing an optical analysis of a dry powder medicament plume discharged from the inhaler upon actuation. More particularly, embodiments of the invention comprise illuminating the dry powder plume with a source of electromagnetic radiation and capturing one or more images of a pattern of radiation reflected or diffracted by the illuminated plume. The images are subsequently processed to determine and/or analyse one or more geometric and/or dynamic characteristics of the plume.

5. 发明申请

US20220203050A1 INHALER SYSTEM 有权
公开(公告)号：US20220203050A1
公开(公告)日：2022-06-30
申请号：US17607442
申请日：2020-04-30
申请人： Norton (Waterford) Limited
发明人： Mark Milton-Edwards , Guilherme Safioti , Lena Granovsky , Michael Reich
IPC分类号： A61M15/00 , G16H20/13
摘要： Provided is a system (10) for determining a probability of a CORD exacerbation in a subject. The system comprises a first inhaler (100) for delivering a rescue medicament to the subject. The rescue medicament may be suitable for treating the subject's acute respiratory disease, for example by effecting rapid dilation of the bronchi and bronchioles upon inhalation of the medicament. The first inhaler has a use-detection system (12B) configured to determine a rescue inhalation performed by the subject using the first inhaler. The system optionally includes a second inhaler for delivering a maintenance medicament to the subject during a routine inhalation A sensor system (12A) is configured to measure a parameter relating to airflow during the rescue inhalation and/or during the routine inhalation, when the second inhaler is included in the system. The system further comprises a processor (14) configured to determine a number of the rescue inhalations during a first time period, and receive the parameter measured for at least some of the rescue and/or routine inhalations. The processor then determines, using a weighted model, the probability of the CORD exacerbation based on the number of rescue inhalations and the parameters. The model is weighted such that the parameters are more significant in the probability determination than the number of rescue inhalations. Further provided is a method for determining the probability of a COPD exacerbation in a subject, which method employs the weighted model.

6. 发明申请

US20220143337A1 INHALATION DEVICE WITH INTEGRATED ELECTRONICS 有权
公开(公告)号：US20220143337A1
公开(公告)日：2022-05-12
申请号：US17583792
申请日：2022-01-25
申请人： NORTON (WATERFORD) LIMITED
发明人： Dong Yang , Dylan A. Moorhouse
IPC分类号： A61M15/00
摘要： A device for delivering medication to a user may include a circular or elliptical body that include a mouthpiece, a flexible strip of medication, a lever, and a mouthpiece cover, where the mouthpiece cover is rotatable about the body. The electronics module may include a communication circuit, a sensor system, and a switch. The lever may be configured to actuate the switch when the lever is moved from a closed position to an open position. The lever is configured to advance a dose of medication on the flexible strip when moved from the closed position to the open position. When actuated, the switch may be configured to switch the electronics module from an off state to an active state wen the lever is actuated for a first time by a user. Thereafter, the electronics module is configured to not return to the off state.

7. 发明申请

US20210402111A1 INHALATION MONITORING SYSTEM AND METHOD 有权
公开(公告)号：US20210402111A1
公开(公告)日：2021-12-30
申请号：US17468928
申请日：2021-09-08
申请人： Norton (Waterford) Limited
发明人： Mark Milton-Edwards , Henry Chrystyn , Mark Steven Morrison , Douglas E. Weitzel
IPC分类号： A61M15/00 , A61B5/00 , A61M16/00 , G16H20/10 , G16Z99/00 , A61B5/087 , A61B5/091
摘要： An inhalation monitoring system includes an inhaler having a medicament delivery apparatus configured to deliver medicament to a user during an inhalation of the user; inhalation monitoring apparatus, configured to, during the inhalation, gather data for determining a measure of the user's lung function and/or lung health; and a processor configured to receive the data from the inhalation monitoring apparatus and, using the data, determine a measure of the user's lung function and/or lung health.

8. 发明申请

US20210393893A1 INHALER SYSTEM 有权
公开(公告)号：US20210393893A1
公开(公告)日：2021-12-23
申请号：US16906896
申请日：2020-06-19
申请人： Norton (Waterford) Limited
发明人： Xinyu Liu , Jenna-Leigh Meola , Cody Goldberg , Jinn Kim , Sunil Kumar Mishra , Vered Ben-Anat
IPC分类号： A61M15/00 , G16H20/13 , G06F21/60 , H04L29/06 , G06K7/14
摘要： Provided is a system comprising a plurality of inhalers that each include a processor configured to determine a value of a usage parameter relating to use of the respective first inhaler, encrypt data based on the value, and transmit the encrypted data. At least two of the inhalers include different medicament, such as a rescue medicament and a maintenance medicament. The system includes an external device that includes a processor configured to distinguish between the encrypted data of each respective inhaler, determine respective usage information relating to each of the distinct types of medicament based on the respective encrypted data, and control a user interface (e.g., of the external device) to communicate the usage information related to each inhaler and/or each respective type of medicament.

9. 发明授权

US11173259B2 Drug delivery device with electronics and power management 有权
公开(公告)号：US11173259B2
公开(公告)日：2021-11-16
申请号：US16921193
申请日：2020-07-06
申请人： Norton (Waterford) Limited
发明人： Enrique Calderon Oliveras , Amir Kesten
IPC分类号： A61M15/00
摘要： A system may limit the number of times an inhalation device transmits inhalation data to a single time to reduce the battery usage of the inhalation device. The system may include an inhalation device that has medicament and an electronics module. The system may limit the number of times the inhalation device transmits new inhalation data to any mobile device to a single time by causing the server to receive the new inhalation data from one of the mobile devices and causing the server to transmit the new inhalation data to other of the mobile devices prior to the other mobile devices transmitting a request for the new inhalation data to the inhalation device. The inhalation device may include a Quick Response (QR) code, and a mobile application may determine at least one of a medication type or a number of doses of the inhalation device from the QR code.

10. 发明申请

US20210293715A1 APPLICATION OF RAMAN SPECTROSCOPY FOR THE MANUFACTURE OF INHALATION POWDERS 有权
公开(公告)号：US20210293715A1
公开(公告)日：2021-09-23
申请号：US17266884
申请日：2019-08-07
申请人： NORTON (WATERFORD) LIMITED
发明人： Hardik Kirtikumar SHAH
IPC分类号： G01N21/65 , A61K45/06 , A61K9/00 , G01N21/85 , G01J3/44 , A61K31/567 , A61K31/138
摘要： The present invention generally relates to improved methods for the manufacture of inhalation powders. More particularly, aspects of the disclosure relate to methods for in-line monitoring of powder blending by Raman spectroscopy.

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