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1. 发明申请

US20180177444A1 Medical Port with Constraining Biasing Element 审中-公开
公开(公告)号：US20180177444A1
公开(公告)日：2018-06-28
申请号：US15389977
申请日：2016-12-23
申请人： NP Medical Inc.
发明人： Todd Chelak , Ian Kimball , Ray Adams , Jeffrey Ransden
IPC分类号： A61B5/15 , A61B5/0215
CPC分类号： A61B5/150221 , A61B5/0215 , A61B5/02152 , A61B5/15003 , A61B5/150328 , A61B5/150992 , A61M39/04 , A61M39/045 , A61M39/223 , A61M39/26 , A61M2039/0072
摘要： A medical port has a housing forming an interior with a fluid inlet and a fluid channel extending from the fluid inlet. The housing also has an exterior wall forming at least one radial opening to the interior. In addition to the housing, the medical port also has a resilient valve element within the housing interior configured to control fluid flow through the inlet, and a biasing element movably couplable with the housing. The resilient valve element has a proximate body portion proximate to the radial opening when in the closed mode. The biasing element also has a constraining portion configured to cooperate with the radial opening to contact at least the proximate body portion of the valve element when in the closed mode. The biasing element constraining portion preferably is configured to normally resist radial outward movement of the proximate body portion when in the closed mode.

2. 发明申请

US20180146866A1 CUTANEOUS BLOOD FLOW MONITORING DEVICE 审中-公开
公开(公告)号：US20180146866A1
公开(公告)日：2018-05-31
申请号：US15574126
申请日：2016-05-16
申请人： VERISKIN, INC.
发明人： Mirianas CHACHISVILIS , Carl Frederick EDMAN , Eugene TU
IPC分类号： A61B5/0215 , A61B8/06 , A61B5/00 , A61B5/022 , A61B5/01
CPC分类号： A61B5/02152 , A61B5/0095 , A61B5/01 , A61B5/022 , A61B5/0261 , A61B5/1101 , A61B5/14539 , A61B5/441 , A61B5/444 , A61B5/6843 , A61B5/7257 , A61B8/06 , A61B2562/0233 , A61B2562/046
摘要： A method and a device for diagnostic of skin cancer and other mammalian skin tissue pathologies are described. The method relies on determination of pathological changes in tissue vascularization and capillary blood flow. The device uses photonic or ultrasound emitters and detectors to characterize temporal and spatial changes in blood flow associated with pulsative actions of the heart.

3. 发明授权

US09968727B2 Systems, devices, and methods for organ retroperfusion along with regional mild hypothermia 有权
公开(公告)号：US09968727B2
公开(公告)日：2018-05-15
申请号：US13965533
申请日：2013-08-13
申请人： CVDevices, LLC
发明人： Ghassan S. Kassab , Jose A. Navia, Sr.
IPC分类号： A61M1/36 , A61B5/0215 , A61F2/06 , A61B5/00 , A61B17/12 , A61M27/00 , A61M25/10 , A61B17/00 , A61B17/11
CPC分类号： A61M1/369 , A61B5/02152 , A61B5/6852 , A61B17/12036 , A61B17/1204 , A61B17/12109 , A61B17/12136 , A61B17/1214 , A61B2017/00026 , A61B2017/00199 , A61B2017/00212 , A61B2017/00221 , A61B2017/00252 , A61B2017/1107 , A61B2017/1135 , A61B2017/1205 , A61F2/06 , A61F2002/065 , A61M1/3653 , A61M1/3659 , A61M27/00 , A61M2025/1052 , A61M2025/1097 , A61M2205/3523 , A61M2205/3561
摘要： Systems, devices, and methods for organ retroperfusion along with regional mild hypothermia. In at least one embodiment of a method of organ perfusion of the present disclosure, the method comprises the steps of positioning at least part of a first catheter having a cannula within an artery of a patient, the first catheter configured to permit arterial blood to flow therethrough and further configured to permit a portion of the arterial blood to flow through the cannula, positioning at least part of a second catheter within a vein of the patient at or near a target organ, the second catheter configured to receive some or all of the portion of the arterial blood, connecting the cannula of the first catheter to a portion of the second catheter so that some or all of the portion of the arterial blood flowing through the cannula is provided into the vein to treat a condition or disease of the target organ, and reducing and/or regulating a temperature of blood flowing through the cannula using a regional hypothermia system operably coupled to the cannula.

4. 发明申请

US20180056034A1 CENTRAL VENOUS CATHETER ACCESS ASPIRATION SYSTEM 审中-公开
公开(公告)号：US20180056034A1
公开(公告)日：2018-03-01
申请号：US15684884
申请日：2017-08-23
申请人： Jacob Cynamon
发明人： Jacob Cynamon
IPC分类号： A61M25/00 , A61B5/1459
CPC分类号： A61M25/0029 , A61B5/02152 , A61B5/1459 , A61B5/15003 , A61B5/150221 , A61B5/150236 , A61B5/150992 , A61M1/00 , A61M25/0068 , A61M39/22 , A61M39/24 , A61M2025/0031
摘要： A central venous catheter access aspiration system using a single connection is provided.

5. 发明申请

US20180020935A1 INTRAVENOUS ACCESS DEVICE DETECTING INTRAVENOUS INFILTRATION AND IN-VEIN PLACEMENT 审中-公开
公开(公告)号：US20180020935A1
公开(公告)日：2018-01-25
申请号：US15547935
申请日：2016-02-03
申请人： Vanderbilt University
发明人： Susan S. Eagle , Colleen Brophy , Kyle Mitchell Hocking , Franz Baudenbacher , Richard Boyer
IPC分类号： A61B5/0215 , A61B5/00 , A61M5/158 , A61M5/168
CPC分类号： A61B5/02152 , A61B5/7235 , A61B5/7257 , A61M5/158 , A61M5/16854 , A61M2005/1588
摘要： Aspects of the invention relates to systems and methods for monitoring an intravenous (IV) line functionality of an IV device. In one embodiment, the system includes an IV catheter to be inserted into the vein of the living subject, at least one pressure sensor in fluid communication with the IV catheter to acquire peripheral venous signals; and a processing device. The processing device receives the peripheral venous signals from the pressure sensor, performs a spectral analysis on the peripheral venous signals to obtain a peripheral venous pressure frequency spectrum, and then performs a statistical analysis on amplitudes of peaks of the peripheral venous pressure frequency spectrum to determine an IV line functionality of the IV catheter in real time. When the IV line functionality indicates IV infiltration, the processing device may control the fluid controlling device to stop the fluid flow from the fluid source to the IV catheter.

6. 发明授权

US09782279B2 Systems, devices, and methods for autoretroperfusion 有权
公开(公告)号：US09782279B2
公开(公告)日：2017-10-10
申请号：US14546233
申请日：2014-11-18
申请人： CVDevices, LLC
发明人： Ghassan S. Kassab
IPC分类号： A61M1/36 , A61F2/856 , A61B5/0215 , A61M27/00 , A61M25/04 , A61B17/00 , A61F2/958 , A61M1/10 , A61M25/00 , A61M25/10
CPC分类号： A61F2/856 , A61B5/02152 , A61B17/00234 , A61B2017/00243 , A61F2/958 , A61F2250/001 , A61F2250/0013 , A61M1/1008 , A61M1/1018 , A61M1/106 , A61M1/1072 , A61M1/1086 , A61M1/125 , A61M1/3613 , A61M1/3639 , A61M1/3653 , A61M1/3659 , A61M25/007 , A61M25/04 , A61M27/00 , A61M2025/1052 , A61M2025/1097 , A61M2205/3523 , A61M2205/3561 , A61M2205/50
摘要： Devices, systems, and methods for autoretroperfusion. In at least one embodiment of a perfusion system of the present disclosure, the system comprises a first catheter having a proximal end, a distal end, and a first lumen therethrough, the distal end configured for insertion into a luminal organ of a patient, a coupler defining an outlet port and a first port, the coupler configured to engage the proximal end of the first catheter at the outlet port and to receive blood from a blood supply through the first port, a first tube having a proximal end, a distal end, and a lumen therethrough, the distal end of the first tube configured to engage the first port of the coupler and to receive the blood from the blood supply, and a first flow regulator in communication with one or more of the coupler and the first tube, the first flow regulator operable to regulate a flow and/or a pressure of the blood through at least part of the system, wherein the system is configured to permit the blood from the blood supply to flow through the first tube, the coupler, and the first catheter into the patient to treat a patient condition.

7. 发明申请

US20170281020A1 Rapid Detection of Bleeding Following Injury 审中-公开
公开(公告)号：US20170281020A1
公开(公告)日：2017-10-05
申请号：US15620701
申请日：2017-06-12
申请人： Flashback Technologies, Inc. , The Regents of the University of Colorado, a body corporate
发明人： Isobel Jane Mulligan , Gregory Zlatko Grudic , Steven L. Moulton
IPC分类号： A61B5/02 , A61B5/0205 , A61B5/00
CPC分类号： A61B5/02042 , A61B5/002 , A61B5/0075 , A61B5/02028 , A61B5/0205 , A61B5/02152 , A61B5/02241 , A61B5/02416 , A61B5/029 , A61B5/031 , A61B5/0402 , A61B5/0476 , A61B5/0496 , A61B5/0809 , A61B5/14532 , A61B5/14546 , A61B5/14551 , A61B5/4836 , A61B5/4848 , A61B5/4875 , A61B5/6826 , A61B5/7246 , A61B5/7267 , A61B5/7275 , A61B5/742 , A61B7/04 , A61B8/488 , A61B2562/0219 , A61M1/1613 , G06F19/3468 , G16H20/17 , G16H40/63 , G16H50/20 , G16H50/30 , G16H50/50 , G16H50/70
摘要： Novel tools and techniques are provided for assessing, predicting and/or estimating a probability that a patient is bleeding, in some cases, noninvasively. In various embodiments, tools and techniques are provided for implementing rapid detection of bleeding of the patient or implementing assessment, prediction, or estimation of a probability of bleeding of the patient following injury, in some instances, in real-time before, during, and after fluid resuscitation. According to some embodiments, one or more sensors might monitor physiological data of the patient before, during, and after resuscitation following injury. A computer system might receive and analyze the physiological data, and might estimate a probability that the patient is bleeding, based at least in part on the analyzed physiological data. An indication of at least one of an assessment, prediction, or estimate of a probability that the patient is bleeding may then be displayed on a display device.

8. 发明授权

US09504781B2 Peripheral arterialization devices and methods of using the same 有权
标题翻译：外周动脉化装置及其使用方法
公开(公告)号：US09504781B2
公开(公告)日：2016-11-29
申请号：US14093300
申请日：2013-11-29
申请人： Ghassan S. Kassab , Jose A. Navia, Sr.
发明人： Ghassan S. Kassab , Jose A. Navia, Sr.
IPC分类号： A61M1/36 , A61B5/0215 , A61F2/06 , A61B17/12 , A61M27/00 , A61B17/00 , A61B17/11 , A61M25/10
CPC分类号： A61F2/06 , A61B5/02152 , A61B17/11 , A61B17/12036 , A61B17/1204 , A61B17/12109 , A61B17/12136 , A61B17/1214 , A61B2017/00026 , A61B2017/00199 , A61B2017/00212 , A61B2017/00221 , A61B2017/00252 , A61B2017/1107 , A61B2017/1135 , A61B2017/1205 , A61F2002/065 , A61M1/3653 , A61M1/3655 , A61M1/3659 , A61M27/00 , A61M2025/1052 , A61M2025/1097 , A61M2205/3523 , A61M2205/3561
摘要： Peripheral arterialization devices and methods of using the same. In an exemplary embodiment of a catheter for facilitating venous arterialization of the present disclosure, the catheter comprises an elongated body extending from a proximal end to a distal end and having a lumen defined therethrough along a longitudinal length of the elongated body, the elongated body configured to attach to a graft at or near the proximal end of the elongated body and further configured to permit fluid to flow through the graft, through the lumen, and out of one or more apertures defined within the elongated body at or near the distal end to facilitate venous arterialization upon at least partial implantation of the catheter into a vein of a patient.
摘要翻译：外周动脉化装置及其使用方法。在用于促进本公开的静脉动脉化的导管的示例性实施例中，导管包括从近端延伸到远端的细长体，并且具有沿着细长体的纵向长度限定穿过的内腔，细长体构造以在细长体的近端处或附近附接到移植物，并进一步构造成允许流体通过内腔流过移植物，并且从远端处或附近限定在细长体内的一个或多个孔中，在将导管至少部分植入患者的静脉中时促进静脉动脉化。

9. 发明申请

US20160157787A1 AUTOMATED IDENTIFICATION AND CLASSIFICATION OF INTRAVASCULAR LESIONS 审中-公开
标题翻译：自动识别和分类血管内皮细胞
公开(公告)号：US20160157787A1
公开(公告)日：2016-06-09
申请号：US14961656
申请日：2015-12-07
申请人： VOLCANO CORPORATION
发明人： Fergus Merritt , Andrew Tochterman , Jacqueline Keller
IPC分类号： A61B5/00 , A61B5/026 , A61B6/03 , A61B5/0215 , A61B5/02 , A61B6/00
CPC分类号： A61B5/7271 , A61B1/3137 , A61B5/0073 , A61B5/02007 , A61B5/0215 , A61B5/02152 , A61B5/026 , A61B5/066 , A61B5/7425 , A61B6/032 , A61B6/12 , A61B6/504 , A61B8/0891 , A61B8/12 , G16H20/40 , G16H30/40 , G16H50/20
摘要： Devices, systems, and methods of mapping a vessel system of a patient and identifying lesions therein are disclosed. This includes a method of evaluating a vessel of a patient, the method comprising obtaining image data for the vessel of the patient, obtaining physiological measurements for the vessel of the patient, co-registering the obtained physiological measurements with the obtained image data such that the physiological measurements are associated with corresponding portions of the vessel of the patient, analyzing the co-registered physiology measurements to determine a classification of a lesion within the vessel of the patient, and outputting, to a user interface, the classification of the lesion. Other associated methods, systems, and devices are also provided herein.
摘要翻译：公开了用于映射患者的血管系统并鉴定病变的装置，系统和方法。这包括评估患者血管的方法，所述方法包括获得患者血管的图像数据，获得患者血管的生理测量值，将获得的生理测量结果与所获得的图像数据共同对准，使得生理测量与患者血管的相应部分相关联，分析共同注册的生理学测量结果，以确定患者血管内病变的分类，并向用户界面输出损伤的分类。本文还提供了其他相关联的方法，系统和设备。

10. 发明申请

US20160074571A1 CONTROL UNIT AND METHOD FOR DETERMINING THE PRESSURE IN A BLOOD VESSEL, IN PARTICULAR IN AN ARTERIOVENOUS FISTULA 审中-公开
标题翻译：用于确定血管中的压力的控制单元和方法，特别是在异常血液中
公开(公告)号：US20160074571A1
公开(公告)日：2016-03-17
申请号：US14786687
申请日：2014-04-17
申请人： FRESENIUS MEDICAL CARE DEUTSCHLAND GMBH
发明人： Pascal KOPPERSCHMIDT
IPC分类号： A61M1/36 , A61B5/00
CPC分类号： A61M1/3656 , A61B5/02152 , A61B5/02158 , A61B5/6866 , A61M2205/3303 , A61M2205/3341 , A61M2205/3344 , A61M2205/3358 , A61M2230/04
摘要： The invention relates to a control unit (30) for determining the pressure in a blood vessel (A, V, F), in particular in an arteriovenous fistula (F), which is in fluid connection with at least one section (28, 41) of a blood line system (39), in particular an extracorporeal blood circulation (II), at least one pressure-generating device (3, 8, 19, 24, 26) being assigned to the blood line system (39), this pressure-generating device being suitable for acting on the section (28, 41), and the control unit (30) being configured to perform the following steps:a) being sure that none of the at least one pressure-generating device (3, 8, 19, 24, 26) acts on the section (28, 41),b) interrupting the fluid connection of the section (28, 41) with the blood vessel (A, V, F) by triggering an interrupt means (11, 29),c) setting the pressure in the section (28, 41) at a predetermined ideal value, in particular at the ambient pressure, with the help of a pressure sensor (13, 14) in the section (28, 41),d) restoring the fluid connection of the section (28, 41) with the blood vessel (A, V, F) by triggering the interrupt means (11, 29), ande) measuring a resulting pressure in the section (28, 41) with the help of the pressure sensor (13, 14).
摘要翻译：本发明涉及一种用于确定血管（A，V，F）中的压力的控制单元（30），特别是在静脉瘘（F）中，其与至少一个部分（28,41）流体连通），血管系统（39），特别是体外血液循环（II）的至少一个压力产生装置（3,8,19,24,26）被分配给血液系统（39），该压力发生装置适于作用在所述部分（28,41）上，并且所述控制单元（30）被配置为执行以下步骤：a）确保所述至少一个压力产生装置（3， 8,29,26）作用于所述部分（28,41），b）通过触发中断装置（11）中断所述部分（28,41）与所述血管（A，V，F）的流体连接，29），c）借助于所述部分（28,41）中的压力传感器（13,14）将所述部分（28,41）中的压力设定在预定理想值，特别是在环境压力下， 41），d）通过触发中断装置（11,29）来恢复部分（28,41）与血管（A，V，F）的流体连接，以及e）测量所述部分中产生的压力在压力传感器（13,14）的帮助下，可以利用压力传感器（28,141）。

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