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1. 发明申请

US20170203043A1 Medical Delivery Device with Laminated Stopper 审中-公开
公开(公告)号：US20170203043A1
公开(公告)日：2017-07-20
申请号：US15404892
申请日：2017-01-12
申请人： W. L. Gore & Associates, Inc.
发明人： Greg Rusch , Robert C. Basham
IPC分类号： A61M5/315 , A61L31/04
CPC分类号： A61M5/31505 , A61L31/048 , A61M5/31513 , A61M2005/3101 , A61M2005/31506 , A61M2205/0216 , A61M2205/0222 , A61M2205/0238
摘要： The present disclosure relates to a medical delivery device that includes a barrel having an inner surface, a plunger rod having a distal end inserted within the barrel, and a stopper attached to the distal end of the plunger rod and contacting at least a portion of the inner surface of the barrel. In at least one embodiment, the inner surface is hydrophilic. The stopper may include an elastomeric body, one or more fluoropolymer layers, and two or more ribs laminated with the one or more fluoropolymer layers. In some embodiments, the contact width between at least one rib having a sealing surface and the portion of the inner surface of the barrel measured at a compressibility of greater than about 7.9% of the stopper is less than about 1.0 mm.

2. 发明授权

US09707348B2 Antiseptic cap with thread cover 有权
公开(公告)号：US09707348B2
公开(公告)日：2017-07-18
申请号：US12214526
申请日：2008-06-19
申请人： William Anderson , Mark Wilson , Gary Henniger , Larry Colquitt , Christopher E. Gardner
发明人： William Anderson , Mark Wilson , Gary Henniger , Larry Colquitt , Christopher E. Gardner
IPC分类号： A61M5/315 , A61M39/02 , A61M39/16 , A61M39/20 , A61M5/00 , A61M5/31 , A61M5/34 , A61M39/10
CPC分类号： A61M5/31511 , A61M5/002 , A61M5/3135 , A61M5/3137 , A61M5/347 , A61M39/02 , A61M39/16 , A61M39/162 , A61M39/20 , A61M2005/3104 , A61M2005/31506 , A61M2039/1033
摘要： A syringe assembly including: (1) a syringe barrel defining a chamber; (2) a plunger mounted in the chamber and moveable with respect to the barrel; and (3) a cap assembly containing a cap and an absorbent material is removably attached to the plunger.

3. 发明授权

US09700677B2 Antiseptic cap with antiseptic 有权
公开(公告)号：US09700677B2
公开(公告)日：2017-07-11
申请号：US14500090
申请日：2014-09-29
申请人： Excelsior Medical Corporation
发明人： William Anderson , Mark Wilson , Gary Henniger , Larry Colquitt , Christopher E. Gardner
IPC分类号： A61M5/315 , A61M39/02 , A61M39/16 , A61M39/20 , A61M5/00 , A61M5/31 , A61M5/34 , A61M39/10
CPC分类号： A61M5/31511 , A61M5/002 , A61M5/3135 , A61M5/3137 , A61M5/347 , A61M39/02 , A61M39/16 , A61M39/162 , A61M39/20 , A61M2005/3104 , A61M2005/31506 , A61M2039/1033
摘要： A syringe assembly including: (1) a syringe barrel defining a chamber; (2) a plunger mounted in the chamber and moveable with respect to the barrel; and (3) a cap assembly containing a cap and an absorbent material is removably attached to the plunger.

4. 发明授权

US09700676B2 Method of cleaning and covering an access site 有权
公开(公告)号：US09700676B2
公开(公告)日：2017-07-11
申请号：US13560499
申请日：2012-07-27
申请人： William Anderson , Mark Wilson , Gary Henniger , Larry Colquitt , Christopher E. Gardner
发明人： William Anderson , Mark Wilson , Gary Henniger , Larry Colquitt , Christopher E. Gardner
IPC分类号： A61M5/315 , A61M39/02 , A61M39/16 , A61M39/20 , A61M5/00 , A61M5/31 , A61M5/34 , A61M39/10
CPC分类号： A61M5/31511 , A61M5/002 , A61M5/3135 , A61M5/3137 , A61M5/347 , A61M39/02 , A61M39/16 , A61M39/162 , A61M39/20 , A61M2005/3104 , A61M2005/31506 , A61M2039/1033
摘要： A syringe assembly including: (1) a syringe barrel defining a chamber; (2) a plunger mounted in the chamber and moveable with respect to the barrel; and (3) a cap assembly containing a cap and an absorbent material is removably attached to the plunger.

5. 发明授权

US09669165B2 Syringe with two-stage sealing pressure 有权
公开(公告)号：US09669165B2
公开(公告)日：2017-06-06
申请号：US13829251
申请日：2013-03-14
申请人： AbbVie Inc.
发明人： Sean E. Mackey , Ji Zhou , Martin J. Gibler , Dennis Y. Lee
IPC分类号： A61M5/14 , A61M5/315 , A61M5/145 , A61M5/31 , A61J7/00 , A61J15/00 , A61M5/00
CPC分类号： A61M5/31513 , A61J7/0053 , A61J15/0015 , A61J15/0061 , A61J15/0069 , A61J15/0076 , A61M5/002 , A61M5/14546 , A61M5/3135 , A61M5/31501 , A61M5/31505 , A61M2005/3101 , A61M2005/3106 , A61M2005/3131 , A61M2005/31506 , A61M2205/8206
摘要： A syringe includes a barrel, a plunger, and a sealing member creating a seal between the plunger and the barrel. The barrel includes a first portion with a first inner diameter and a second portion with a second inner diameter that is larger than the first inner diameter. The sealing member engages the first portion of the barrel to give rise to a first contact pressure when the barrel is filled with product. The first contact pressure is sufficient to maintain a gas-tight seal over the expected temperature ranges −25° C. to 40° C. A first force is applied to the plunger to overcome the first contact pressure and move the plunger out of the first portion and into the second portion to dispense product. The sealing member engages the second portion of the barrel to give rise to a second contact pressure that is lower than the first contact pressure. A second force lower than the first force is sufficient to overcome the second contact pressure and move the plunger in the second portion to continue dispensing product. The syringe may include a restraining element for accommodating expansion of the product during freezing.

6. 发明授权

US09415155B2 Injector piston nest 有权
标题翻译：注射器活塞套
公开(公告)号：US09415155B2
公开(公告)日：2016-08-16
申请号：US12224392
申请日：2006-02-28
申请人： Hiroshi Togashi , Jansen Hubert
发明人： Hiroshi Togashi , Jansen Hubert
IPC分类号： A61B19/02 , A61M5/00 , A61M5/315
CPC分类号： A61M5/008 , A61M5/002 , A61M2005/31506
摘要： A container for receiving or storing or carrying pistons for injectors, the container having a base plate and hollow cylindrical piston storage parts (the container being hereafter referred to as a piston nest). Each of the hollow cylindrical piston receiving parts is formed either by making it vertically penetrate through the basic plate, with one side of the base plate functioning as one opening end, and project from the other side or by making it vertically penetrate through the base plate and project from both sides of the base plate. Preferably, each piston receiving part has a swelled part where a part of the inner peripheral wall surface of the piston receiving part is swelled inward. The pistons for injectors are received in the piston receiving parts.
摘要翻译：一种用于接收或储存或运载用于喷射器的活塞的容器，该容器具有基板和中空圆柱形活塞储存部分（以下称为活塞套）。每个中空的圆柱形活塞接收部件通过使其垂直地穿过基板而形成，基板的一侧用作一个开口端，并且从另一侧突出或通过使其垂直穿过基板并从基板两侧进行设计。优选地，每个活塞接收部分具有膨胀部分，其中活塞接收部分的内周壁表面的一部分向内膨胀。用于喷射器的活塞被容纳在活塞接收部分中。

7. 发明授权

US09186464B2 Dosing injector 有权
标题翻译：给药注射器
公开(公告)号：US09186464B2
公开(公告)日：2015-11-17
申请号：US13828159
申请日：2013-03-14
申请人： Allergan, Inc.
发明人： Ethan Franklin
IPC分类号： A61M5/00 , A61M5/315 , A61M5/31
CPC分类号： A61M5/31526 , A61M5/3129 , A61M5/31511 , A61M5/3157 , A61M5/3158 , A61M5/31581 , A61M5/31595 , A61M2005/31506 , A61M2005/31508
摘要： A metered dose syringe includes a barrel having an open end and a opposing spaced apart port adapted to receive a needle. A plunger rod is provided and slidably disposed within the barrel through the barrel open end. Structure interconnected with the barrel and the plunger rod is provided for enabling stepwise movement of the plunger rod within the barrel. A syringe within the scope of our present invention permits injection of repeated and accurate doses due to the physical stops or dosage administered indicators.
摘要翻译：计量剂量注射器包括具有开口端的筒体和适于接纳针头的相对间隔开的口。提供柱塞杆并且通过筒体开口端可滑动地设置在筒体内。设置与筒体和柱塞杆相互连接的结构，用于使柱塞杆在筒体内逐步移动。在本发明范围内的注射器由于物理停止或给药指示剂而允许注射重复且准确的剂量。

8. 发明授权

US09022992B2 Drug delivery device 有权
标题翻译：给药装置
公开(公告)号：US09022992B2
公开(公告)日：2015-05-05
申请号：US13512180
申请日：2010-12-02
申请人： Michael Helmer , Steffen Raab
发明人： Michael Helmer , Steffen Raab
IPC分类号： A61M5/00 , A61M5/315 , A61M5/31 , A61M5/24
CPC分类号： A61M5/31555 , A61M5/24 , A61M5/3146 , A61M5/3156 , A61M5/3158 , A61M5/31593 , A61M2005/31506
摘要： A drug delivery device comprises a housing and a piston rod arranged in the housing. The piston rod is adapted to be moved along an axial direction to dispense a fluid. A drive member arranged in the housing is operatively coupled to the piston rod and adapted to set up a dose of fluid for dispense in response to a first movement. The drive member is also adapted to move the piston rod to dispense the dose in response to a second movement. The drug delivery device also comprises a pre-dispensing drive member operatively coupled to the drive member and the housing and adapted to move at least the drive member by a pre-dispensing distance between its first and second movement.
摘要翻译：药物输送装置包括设置在壳体中的壳体和活塞杆。活塞杆适于沿轴向移动以分配流体。布置在壳体中的驱动构件可操作地联接到活塞杆并且适于设置响应于第一运动而分配的剂量的流体。驱动构件还适于移动活塞杆以响应于第二运动而分配剂量。药物递送装置还包括预分配驱动构件，其可操作地联接到驱动构件和壳体并且适于在其第一和第二运动之间通过预分配距离至少移动驱动构件。

9. 发明申请

US20150018774A1 Antiseptic Cap with Antiseptic 有权
标题翻译：防腐帽与防腐剂
公开(公告)号：US20150018774A1
公开(公告)日：2015-01-15
申请号：US14500090
申请日：2014-09-29
申请人： Excelsior Medical Corporation
发明人： William Anderson , Mark Wilson , Gary Henniger , Larry Colquitt , Christopher E. Gardner
IPC分类号： A61M39/16 , A61M39/20 , A61M5/315
CPC分类号： A61M5/31511 , A61M5/002 , A61M5/3135 , A61M5/3137 , A61M5/347 , A61M39/02 , A61M39/16 , A61M39/162 , A61M39/20 , A61M2005/3104 , A61M2005/31506 , A61M2039/1033
摘要： A syringe assembly including: (1) a syringe barrel defining a chamber; (2) a plunger mounted in the chamber and moveable with respect to the barrel; and (3) a cap assembly containing a cap and an absorbent material is removably attached to the plunger.
摘要翻译：一种注射器组件，包括：（1）限定腔室的注射器筒; （2）柱塞，其安装在所述室中并相对于所述筒可移动; 和（3）包含盖和吸收材料的盖组件可移除地附接到柱塞。

10. 发明申请

US20140228802A1 SYRINGE WITH TWO-STAGE SEALING PRESSURE 有权
标题翻译：具有两段密封压力的SYRINGE
公开(公告)号：US20140228802A1
公开(公告)日：2014-08-14
申请号：US13829251
申请日：2013-03-14
申请人： AbbVie Inc.
发明人： Sean E. Mackey , Ji Zhou , Martin J. Gibler , Dennis Lee
IPC分类号： A61M5/14
CPC分类号： A61M5/31513 , A61J7/0053 , A61J15/0015 , A61J15/0061 , A61J15/0069 , A61J15/0076 , A61M5/002 , A61M5/14546 , A61M5/3135 , A61M5/31501 , A61M5/31505 , A61M2005/3101 , A61M2005/3106 , A61M2005/3131 , A61M2005/31506 , A61M2205/8206
摘要： A syringe includes a barrel, a plunger, and a sealing member creating a seal between the plunger and the barrel. The barrel includes a first portion with a first inner diameter and a second portion with a second inner diameter that is larger than the first inner diameter. The sealing member engages the first portion of the barrel to give rise to a first contact pressure when the barrel is filled with product. The first contact pressure is sufficient to maintain a gas-tight seal over the expected temperature ranges −25° C. to 40° C. A first force is applied to the plunger to overcome the first contact pressure and move the plunger out of the first portion and into the second portion to dispense product. The sealing member engages the second portion of the barrel to give rise to a second contact pressure that is lower than the first contact pressure. A second force lower than the first force is sufficient to overcome the second contact pressure and move the plunger in the second portion to continue dispensing product. The syringe may include a restraining element for accommodating expansion of the product during freezing.
摘要翻译：注射器包括筒，柱塞和在柱塞和筒之间形成密封的密封构件。枪管包括具有第一内径的第一部分和具有大于第一内径的第二内径的第二部分。密封构件与筒体的第一部分接合以在桶体填充产品时产生第一接触压力。第一接触压力足以在-25℃至40℃的预期温度范围内保持气密密封。将第一力施加到柱塞以克服第一接触压力并将柱塞移出第一接触压力部分并进入第二部分以分发产品。密封构件与筒的第二部分接合以产生低于第一接触压力的第二接触压力。低于第一力的第二力足以克服第二接触压力并且使第二部分中的柱塞移动以继续分配产物。注射器可以包括用于在冷冻期间容纳产品的膨胀的约束元件。

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