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1. 发明授权

US11628256B2 Plunger sub-assembly for a prefilled medicament injector, a prefilled medicament injector and method for assembling a prefilled medical injector 有权
公开(公告)号：US11628256B2
公开(公告)日：2023-04-18
申请号：US16473833
申请日：2017-12-29
申请人： Novo Nordisk A/S
发明人： Jacob Eiland , Frederik Holten-Tingleff , Peter Bjerrum , Jonas Moerkeberg Torry-Smith
IPC分类号： A61M5/20 , A61M5/315 , A61M5/24
摘要： A plunger sub-assembly (40, 60, 70; 80) for a pre-filled medicament injector for expelling a dose of a medicament, comprising: a) a container (60) holding a medicament, the container (60) comprising a body (61) with a proximally facing rim surface (64), and a distally slideable piston (63); b) a plunger (40); and c) a tolerance compensating element (70; 80) configured to cooperate with the plunger (40) and to cooperate with either the proximally facing rim surface (64) or the piston (63), the tolerance compensating element (70; 80) being rotatable relative to the plunger (40) to adjust the piston (63) end of dose position. The plunger sub-assembly (40, 60, 70; 80) is formed so that end of dose state occurs by the plunger (40) cooperating with the proximally facing rim surface (64). Pre-filled medicament injectors and methods of assembling a pre-filled medicament injector are further described.

2. 发明申请

US20230109835A1 Two-Stage Reconstituting Injector 有权
公开(公告)号：US20230109835A1
公开(公告)日：2023-04-13
申请号：US18064969
申请日：2022-12-13
申请人： Antares Pharma, Inc.
发明人： Thomas E. Kramer , Peter L. Sadowski
IPC分类号： A61M5/315 , A61M5/20 , A61M5/24 , A61M5/32 , A61M5/19 , A61M5/30
摘要： An injector (10) for injecting a medicament into a patient. The injector includes a container (18) defining a first chamber (22), which contains a fluid therein, and a second chamber (23). The injector also includes an injection conduit (126) configured for directing the fluid fired from the container into the patient. A transfer mechanism is operable by a user to transfer the fluid from the first chamber to the second chamber in a first stage of operation, and a firing mechanism is operable by the user for firing the fluid from the second chamber through the injection conduit in a second stage of operation. An energy source (62) is in powering association with the firing mechanism to drive firing mechanism in the first and second stages.

3. 发明授权

US11617833B2 Self-contained auto-injector 有权
公开(公告)号：US11617833B2
公开(公告)日：2023-04-04
申请号：US16882157
申请日：2020-05-22
申请人： Falco Medical, LLC
发明人： Robert F. Rioux , Matthew Laplaca , Brian Grasso , Matt Bomes
IPC分类号： A61M5/20 , A61M5/24 , A61M5/178 , A61M5/31 , A61M5/30
摘要： A drug self-delivery device comprising a body portion containing a drug vial and a needle assembly, where the body portion is slidably engaged to a trigger portion. When engaged by a user pressing the trigger portion against the user's flesh, the needle assembly relative to the drug vial so as to align a needle port with an integral drug delivery port connected to the drug vial thereby allowing fluid flow of medication through the needle. Seals engaged by a penetration spring prevent loss of medication and prevent the need for direct connection between the needle assembly and the drug vial.

4. 发明申请

US20230098606A1 DEVICES AND METHODS FOR ASSISTING A USER OF A DRUG DELIVERY DEVICE 有权
公开(公告)号：US20230098606A1
公开(公告)日：2023-03-30
申请号：US17940422
申请日：2022-09-08
申请人： AMGEN INC.
发明人： Adam B. McCullough , Basel Hasan Taha , Jimmie L. Ward , Steven William Badelt , Ferry Tamtoro , Huaying Yang , Mark Ka Lai Lee , Desheng Yin , Scott R. Gibson , Donald Busby , Peter V. Shultz , Keith P. Kogler
IPC分类号： A61M5/20 , A61M5/315 , A61M5/32 , A61M5/142 , A61M5/50 , G16H20/17 , G16H40/63 , G16H40/00 , G16H40/67 , G06Q50/22 , G06Q50/00 , A61M5/158 , A61M5/24
摘要： Devices and methods are disclosed for assisting a user of a drug delivery device with an application executing on a mobile computing device. The mobile computing device may receive information from the drug delivery device related to its condition and/or operation and subsequently select an informational and/or instructional prompt to be displayed to the user based on the received information. The mobile computing device may also generate a display in the application including the selected informational prompt and/or the instructional prompt. Accordingly, the user of the drug delivery device can be guided through the drug delivery process in real time, thereby reducing the likelihood of improper or incomplete use of the drug delivery device.

5. 发明申请

US20230072178A1 AUTO INJECTOR WITH CARTRIDGE LOCKING SYSTEM 有权
公开(公告)号：US20230072178A1
公开(公告)日：2023-03-09
申请号：US17985438
申请日：2022-11-11
申请人： Ascendis Pharma A/S
发明人： Thorben Kvisgaard Jacobsen , Jan Olesen
IPC分类号： A61M5/20 , A61M5/24
摘要： An auto injector (4) for administering injection of a medicament from a cartridge containing the medicament, the auto injector (4) comprising: a housing (6); a cartridge receiver (300) with a cartridge receiver compartment (302) configured to receive a cartridge assembly (600), with at least one cartridge retention member (808), when inserted through a cartridge receiver opening (301) along a longitudinal axis (L) in a receiving direction; wherein the cartridge receiver (300) has a passage (316) through which the at least one cartridge retention member (808) travels at least in the receiving direction, and a member (312) preventing movement beyond a retention position in a direction opposite of the receiving direction; an elongated ejector (200) that is configured with: an ejector support face (204) for supporting the cartridge or cartridge assembly (600), a longitudinal ejector slot (228) extending towards the ejector support face (204) from an ejector rest portion (206); wherein the elongated ejector (200) is suspended to move along the longitudinal direction and is spring-loaded in the direction opposite of the receiving direction; and an ejector lock (212) supported for turning at least a fraction of a revolution and maintained in a longitudinal position relative to the housing (6); wherein the ejector lock (212) has a ejector lock support portion (214) that is configured to align with and slide along the longitudinal ejector slot (228) at a first angle and to be brought to align with the ejector rest portion (206) at a second angle.

6. 发明授权

US11596743B2 Clutch assembly with a blocking system for a medical injection device 有权
公开(公告)号：US11596743B2
公开(公告)日：2023-03-07
申请号：US16631307
申请日：2018-03-20
申请人： NEMERA SZCZECIN SPOLKA E OGRANICZONA ODPOWIEDZIALNOSCIA
发明人： Adam Stefanski , Alberto Lozano Platonoff
IPC分类号： A61M5/315 , A61M5/20 , A61M5/24 , A61M5/31
摘要： A clutch assembly with a blocking system for a medical injection device, in which a first ratchet sleeve (3) is mounted on the clutch sleeve (2), the first ratchet sleeve (3) being rotatable in two directions and cooperating with a second ratchet sleeve (4) which is mounted on the first ratchet sleeve (3), the second ratchet sleeve (4) being rotatable only in one direction, the housing (1) has an internal toothed ring (1.1), the first ratchet sleeve (3) has at least one ratchet (3.1), and the second ratchet sleeve (4) has an internal toothed ring (4.1) and at least one ratchet (4.2). The second ratchet sleeve (4) and the housing (1) have blocking means (4.3, 1.2) for preventing the arming of the device when an insufficient volume of the medicament remains in the container, by blocking the rotation of the second ratchet sleeve (4) in relation to the housing (1).

7. 再颁专利

USRE49438E1 Logging device for drug delivery device 有权
公开(公告)号：USRE49438E1
公开(公告)日：2023-02-28
申请号：US17127987
申请日：2020-12-18
申请人： Novo Nordisk A/S
发明人： Jens Christian Andersen , Nikolaj Frogner Krusell , Preben Mikael Nielsen
IPC分类号： A61M5/315 , A61M5/20 , A61M5/24 , A61M5/31 , A61M5/32 , G16H20/13 , G16H20/17 , G16H40/63 , G16Z99/00
摘要： An add-on logging device (100, 300) mounted to a drug delivery device is turned on when the cap is removed. After a given amount of time in inactivity the sensor means of the add-on device is turned off automatically to save energy. If the user takes a dose of drug this is not detected as the add-on device is only turned on when the cap is removed. According to the present invention a warning message is provided when the cap is re-mounted after the sensor means has been turned off automatically, the warning message indicating to a user that an expelled dose may not have been detected.

8. 发明申请

US20230058381A1 SYSTEMS AND METHODS FOR THE INJECTION OF VISCOUS FLUIDS 有权
公开(公告)号：US20230058381A1
公开(公告)日：2023-02-23
申请号：US17796199
申请日：2021-01-28
申请人： Massachusetts Institute of Technology
发明人： Kripa K. Varanasi , Vishnu Jayaprakash , Maxime Costalonga
IPC分类号： A61M5/24 , A61M5/34
摘要： Disclosed herein are systems and methods for the injection of viscous fluids. For example, inventive systems and methods for injecting viscous fluids, such as concentrated drug formulations, via droplet lubrication are described.

9. 发明申请

US20230055427A1 A MEDICAMENT CONTAINER SUPPORT ASSEMBLY 有权
公开(公告)号：US20230055427A1
公开(公告)日：2023-02-23
申请号：US17796908
申请日：2020-11-27
申请人： SHL MEDICAL AG
发明人： Anders Böstrom
IPC分类号： A61M5/24 , A61M5/315
摘要： A support assembly for a medicament container of a medicament delivery device is provided with a container support member having a proximal end and a distal end and configured to partially receive a medicament container, a deformable member arranged between a distal portion of the container support element and the proximal end of a flange of the medicament container, a rear support member arranged to be moved in contact with the distal end of the flange of the medicament container; where the deformable member is deformed by a clamping force generated by the container support member and the flange of the medicament container, such that the deformation of the deformable member is configured to compensate an engineering tolerance of the medicament delivery device.

10. 发明申请

US20230049720A1 METHOD OF SEALING A SYRINGE BARREL 有权
公开(公告)号：US20230049720A1
公开(公告)日：2023-02-16
申请号：US17967482
申请日：2022-10-17
申请人： KAIRISH INNOTECH PRIVATE LIMITED
发明人： Pratul Prakash Potdar , Anil Narayan Narvekar
IPC分类号： A61M5/32 , A61M5/31 , A61M5/50 , A61M5/24 , A61J1/14 , A61M5/34
摘要： Disclosed is a method of sealing a syringe barrel having a syringe tip with a collar. The syringe tip is sealed with a resilient closure. A tamper evident syringe tip cap comprising a cap member and a sleeve member separated by an annular first breaking line is then pushed over the resilient closure, to couple the proximal end of the sleeve member with the collar. The distal end of the resilient closure is accommodated in the cap member and protrudes beyond the sleeve member. The first breaking line is bridged by a coupling strip. For use of the syringe and providing access to the closure, the first breaking line is broken by pivoting the cap member away. The sleeve member remains coupled to the collar. Further tearing the cap member downward causes breaking a second breaking line provided in the sleeve member, thereby enabling removing the entire syringe tip cap.

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