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    • 3. 发明申请
    • Bio-pharmaceutical hose
    • 生物制药软管
    • US20080035228A1
    • 2008-02-14
    • US11503868
    • 2006-08-14
    • Robert Bentley
    • Robert Bentley
    • F16L11/00B29C47/06B29C71/00B29C44/24B29C44/32B29C47/02
    • F16L11/04B29C44/22B29C47/0023B29C47/023B29C59/103B29C59/142B29C59/165B29C2791/009B29K2083/00Y10T428/1393
    • A hose for use in bio-pharmaceutical applications includes an innermost tubular layer made from a fluoropolymer material. The tubular layer has an inner, relatively smooth and pure surface that defines an opening for transfer of various media. A layer of silicone is disposed next to an outer surface of the innermost tubular layer through use of, for example, an extrusion method. The outer surface of the tubular layer may first be modified by various treatments or chemicals to facilitate the adhesion of the silicone layer thereto. The silicone material may be solid or foamed. A reinforcement layer may be disposed adjacent to an outer surface of the silicone layer. The reinforcement layer may be formed of a wire braid having gaps. An outer jacket of silicone may be attached to the reinforcement layer and to the inner silicone layer through the gaps in the reinforcement layer.
    • 用于生物药物应用的软管包括由含氟聚合物材料制成的最内管。 管状层具有内部相对平滑且纯净的表面,其限定用于传送各种介质的开口。 一层硅树脂通过使用例如挤出方法设置在最内管状层的外表面附近。 管状层的外表面可以首先通过各种处理或化学品进行改性,以促进硅氧烷层与其粘合。 硅酮材料可以是固体或发泡的。 加强层可以邻近硅氧烷层的外表面设置。 加强层可以由具有间隙的丝编织物形成。 硅树脂的外套可以通过加强层中的间隙附着到加强层和内部硅氧烷层。
    • 9. 发明授权
    • Method for making a tubular product
    • 管状产品的制造方法
    • US5792401A
    • 1998-08-11
    • US653886
    • 1996-05-28
    • Warren R. Burnham
    • Warren R. Burnham
    • B29C47/00B29C47/02B29C47/06B29C47/90B29C53/58B29C70/50B29C70/82
    • B29C47/903A61M25/0012A61M25/0053B29C47/0016B29C47/0023B29C47/0026B29C47/003B29C47/0033B29C47/023B29C47/025B29C47/128B29C47/90B29C70/50B29C70/82B29C47/0066B29C47/021B29C47/04B29C47/8805B29C47/908B29C53/58B29L2023/22B29L2031/7542
    • A process for making a reinforced tubular product, especially a catheter, in a single extrusion step. A reinforcing member is applied to an extruded thermoplastic catheter body of about its finished size which is softened by heating while tensioning the reinforcing member to control the surface deformation or penetration of the catheter wall by the reinforcing member to produce an irregular surface contour on the catheter body. The catheter body is then smoothed in a sizing die burying the reinforcement to form the finished product. The heating step may be in addition to or substituted by a curing step when a thermosetting or cross-linking material is used for the body. The reinforcement may be braid, or a helical wrap of one or more members applied at one or more controlled angles relative to the axis of the catheter to control the apparent stiffness and torque transmission efficiency of the catheter. The process is particularly adapted to making a catheter having its reinforcement interrupted to provide a unitary non-reinforced distal tip. By this process, the radial location of the reinforcement in the wall of the catheter is easily controlled according to the material of the body, the heating conditions, and the tension on the reinforcing member. Multiple extrusions to form a reinforced catheter body are thus not required.
    • 在单个挤出步骤中制造增强的管状产品,特别是导管的方法。 将加强构件施加到其成品尺寸的挤出热塑性导管体上,其通过加热而软化,同时张紧加强构件以控制加强构件的导管壁的表面变形或穿透,以在导管上产生不规则的表面轮廓 身体。 然后将导管主体平整在一个定型模具中,该模具埋入加强件以形成成品。 当热固性或交联材料用于身体时,加热步骤可以是固化步骤的添加或替代。 加强件可以是编织物,或一个或多个构件的螺旋包裹物,其以相对于导管的轴线的一个或多个受控角度施加以控制导管的表观刚度和扭矩传递效率。 该方法特别适用于制造其加强件中断的导管,以提供一体的非增强的远端尖端。 通过该过程,可以根据身体的材料,加热条件和加强构件上的张力容易地控制加强件在导管壁中的径向位置。 因此不需要多个挤压以形成加强的导管体。