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    • 7. 发明授权
    • Control of polymer surface molecular architecture via amphipathic endgroups
    • 通过两亲性端基控制聚合物表面分子结构
    • US07884171B2
    • 2011-02-08
    • US12638371
    • 2009-12-15
    • Robert S. WardKeith R. McCreaYuan TianJames P. Parakka
    • Robert S. WardKeith R. McCreaYuan TianJames P. Parakka
    • C08G18/00C08G77/04C08G77/22
    • C08G18/6287A61L27/18A61L29/06A61L31/06C08G18/0823C08G18/12C08G18/283C08G18/2865C08G18/289C08G18/5024C08G18/5039C08G18/6283C08G18/6795C08L75/04C08G18/3228
    • Polymers whose surfaces are modified by endgroups that include amphipathic surface-modifying moieties. An amphipathic endgroup of a polymer molecule is an endgroup that contains at least two moieties of significantly differing composition, such that the amphipathic endgroup spontaneously rearranges its positioning in a polymer body to position the moiety on the surface of the body, depending upon the composition of the medium with which the body is in contact, when that re-positioning causes a reduction in interfacial energy. An example of an amphipathic surface-modifying endgroup is one that has both a hydrophobic moiety and a hydrophilic moiety in a single endgroup. For instance, a hydrophilic poly(ethylene oxide) terminated with a hydrophilic hydroxyl group is not surface active in air when the surface-modifying endgroup is bonded to a more hydrophobic base polymer. If the hydroxyl group on the oligomeric poly(ethylene oxide) is replaced by a hydrophobic methoxy ether terminus, the poly(ethylene oxide) becomes surface active in air, and allows the poly(ethylene oxide) groups to crystallize in the air-facing surface. In this example, immersion in water destroys the crystallinity as the poly(ethylene oxide) sorbs water and the hydrophobic methoxy group retreats below the surface of the polymer. Also disclosed are methods and articles of manufacture that make use of these polymers.
    • 其表面被包括两亲表面改性部分的端基修饰的聚合物。 聚合物分子的两亲端基是含有至少两个具有显着不同组成的部分的端基,使得两亲性端基在聚合物体中自发地重排其定位,以将该部分定位在身体的表面上,这取决于 当该重新定位导致界面能量降低时,与身体接触的介质。 两亲性表面改性端基的实例是在单个端基具有疏水部分和亲水部分的实例。 例如,当表面改性端基键合到更疏水的基础聚合物上时,用亲水羟基封端的亲水性聚(环氧乙烷)在空气中不是表面活性的。 如果低聚聚(环氧乙烷)上的羟基被疏水性甲氧基醚末端所代替,则聚(环氧乙烷)在空气中变得表面活性,并允许聚(环氧乙烷)基团在面向空气的表面中结晶 。 在该实施例中,当聚(环氧乙烷)吸附水和疏水性甲氧基在聚合物表面下方退缩时,浸入水中会破坏结晶度。 还公开了利用这些聚合物的方法和制品。