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1. 发明申请

US20190178626A1 EXCHANGEABLE LENS MODULE SYSTEM FOR PROBES OF OPTICAL MEASURING MACHINES 审中-公开
公开(公告)号：US20190178626A1
公开(公告)日：2019-06-13
申请号：US16276370
申请日：2019-02-14
申请人： Quality Vision International, Inc.
发明人： David B. Kay
IPC分类号： G01B9/02 , G01B11/24 , G02B7/14
CPC分类号： G01B9/0205 , G01B9/02035 , G01B11/2441 , G02B7/14
摘要： An interferometric measuring machine includes an exchangeable lens module system for an optical probe. The probe includes a lens body containing the optical apparatus of an interferometer and a lens module containing an objective lens along an object arm of the interferometer that can be exchanged with other lens modules for varying the measuring characteristics of the probe. The lens modules are adapted to accommodate objective lenses having different focal lengths while maintaining a desired optical path length of the object arm of the interferometer.

2. 发明授权

US09897538B2 Method and apparatus for improving image clarity and sensitivity in optical coherence tomography using dynamic feedback to control focal properties and coherence gating 有权
公开(公告)号：US09897538B2
公开(公告)日：2018-02-20
申请号：US10136813
申请日：2002-04-30
申请人： Guillermo J. Tearney , Brett Eugene Bouma
发明人： Guillermo J. Tearney , Brett Eugene Bouma
IPC分类号： A61B5/00 , G01N21/47 , G01B9/02
CPC分类号： G01N21/4795 , A61B5/0066 , A61B5/0068 , A61B5/0084 , A61B5/6852 , A61B5/6853 , G01B9/0205 , G01B9/02063 , G01B9/02068 , G01B9/02083 , G01B9/02085 , G01B9/02091 , G01B2290/35
摘要： Methods for optical imaging, particularly with optical coherence tomography, using a low coherence light beam reflected from a sample surface and compared to a reference light beam, wherein real time dynamic optical feedback is used to detect the surface position of a tissue sample with respect to a reference point and the necessary delay scan range. The delay is provided by a tilting/rotating mirror actuated by a voltage adjustable galvanometer. An imaging probe apparatus for implementing the method is provided. The probe initially scans along one line until it finds the tissue surface, identifiable as a sharp transition from no signal to a stronger signal. The next time the probe scans the next line it adjusts the waveform depending on the previous scan. An algorithm is disclosed for determining the optimal scan range.

3. 发明申请

US20180031363A1 Integrated Optical Coherence Analysis System 审中-公开
公开(公告)号：US20180031363A1
公开(公告)日：2018-02-01
申请号：US15714365
申请日：2017-09-25
申请人： Axsun Technologies, Inc.
发明人： Bartley C. Johnson , Dale C. Flanders
IPC分类号： G01B9/02 , A61B5/00 , G01N21/47
CPC分类号： G01B9/02057 , A61B5/0066 , A61B5/0073 , G01B9/02004 , G01B9/0205 , G01B9/02091 , G01B2290/70 , G01N21/4795
摘要： Optical coherence tomography (OCT) probe and system designs are disclosed that minimize the effects of mechanical movement and strain to the probe to the OCT analysis. It also concerns optical designs that are robust against noise from the OCT laser source. Also integrated OCT system-probes are included that yield compact and robust electro-opto-mechanical systems along with polarization sensitive OCT systems.

4. 发明授权

US09709388B2 Optical inner surface measuring device 有权
公开(公告)号：US09709388B2
公开(公告)日：2017-07-18
申请号：US14717896
申请日：2015-05-20
申请人： NAMIKI SEIMITSU HOUSEKI KABUSHIKI KAISHA
发明人： Hiroshi Yamazaki , Eri Fukushima , Kazumi Yanagiura , Takafumi Asada
IPC分类号： G01B9/02 , G01B11/14 , G01B11/12 , G01B11/24 , A61B1/00 , G01B11/30
CPC分类号： G01B11/14 , A61B1/00165 , A61B1/00172 , G01B9/0205 , G01B9/02076 , G01B11/12 , G01B11/24 , G01B11/2441 , G01B11/30
摘要： Higher-precision measurement is achieved by an optical inner surface measuring device configured to cause a probe to enter into the inner peripheral surface or deep hole of a target object, capture and observe reflection light from the inner surface in a three-dimensional manner, and measure the accuracy of the target object. In a structure including an optical fiber built into a tube, a light path conversion unit arranged at a leading end side of the optical fiber, and a motor configured to rotationally drive the light path conversion unit, a unit for measuring the amount of runout of a rotation shaft unit of the motor is provided. Shape data on the inner peripheral surface of a target object is obtained by calculating at a computer reflection light from the target object, and is modified by displacement amount data from a displacement measurement unit to realize high-precision measurement with no measurement error resulting from runout and rotational vibration of the rotation shaft of the motor.

5. 发明申请

US20170071467A1 ANGULAR MULTIPLEXED OPTICAL COHERENCE TOMOGRAPHY SYSTEMS AND METHODS 审中-公开
标题翻译：角度多重光学相干坐标系统和方法
公开(公告)号：US20170071467A1
公开(公告)日：2017-03-16
申请号：US15343750
申请日：2016-11-04
申请人： AMO WaveFront Sciences, LLC
发明人： Thomas D. Raymond , Devon E. Reid
IPC分类号： A61B3/10 , G01B9/02 , G01N21/47 , A61B3/107
CPC分类号： A61B3/102 , A61B3/1005 , A61B3/107 , A61B5/0066 , G01B9/0205 , G01B9/02087 , G01B9/02091 , G01N21/4795
摘要： Angle multiplexed optical coherence tomography systems and methods can be used to evaluate ocular tissue and other anatomical structures or features of a patient. The angle multiplexed optical coherence tomography system includes a light source, an optical assembly for obtaining a plurality of sample beams corresponding to respective anatomical locations of the eye of the patient, where individual sample beams are associated with a respective non-zero angle relative to a reference beam, and a detection mechanism that detects individual unique interference patterns respectively provided by the plurality of sample beams, for simultaneous evaluation of the anatomical locations.
摘要翻译：角度多重光学相干断层扫描系统和方法可用于评估患者的眼组织和其他解剖结构或特征。角度复用光学相干断层摄影系统包括光源，用于获得与患者眼睛的各个解剖学位置对应的多个样本光束的光学组件，其中各个样本光束相对于相对于非零角度相关联以及检测机构，其检测由多个样本光束分别提供的各个独特的干涉图案，用于同时评估解剖位置。

6. 发明授权

US09322639B2 Calibration jig for optical tomographic imaging apparatus and method for generating a calibration conversion table 有权
公开(公告)号：US09322639B2
公开(公告)日：2016-04-26
申请号：US14505372
申请日：2014-10-02
申请人： TERUMO KABUSHIKI KAISHA
发明人： Daisuke Watanabe , Yuichi Teramura
IPC分类号： G01B11/02 , G01B9/02 , G01D18/00 , G06F17/17
CPC分类号： G01B9/02072 , G01B9/02004 , G01B9/0205 , G01B9/02074 , G01B9/02083 , G01B9/02091 , G01D18/00 , G06F17/17
摘要： A calibration jig allowing simple and repeatable calibration of a probe optical tomographic apparatus is disclosed. The jig includes a holding member removably attachable to an attachment section of the apparatus and a reflective surface held by the holding member. The reflective surface reflects measurement light emitted from an emitting section of the attachment section and directs reflected light back to the emitting section. If a probe of the apparatus is covered with a sheath, the jig may include a light transmitting member, which generates the same dispersion as dispersion at the sheath, between the emitting section and the reflective surface. The reflective surface may be a single reflective surface disposed within an area corresponding to twice a coherence length of the laser light with a zero path position of the reflective surface being the center of the area.

7. 发明授权

US09198573B2 Angular multiplexed optical coherence tomography systems and methods 有权
标题翻译：角多重光学相干断层扫描系统和方法
公开(公告)号：US09198573B2
公开(公告)日：2015-12-01
申请号：US14199161
申请日：2014-03-06
申请人： AMO Wavefront Sciences, LLC.
发明人： Thomas D. Raymond , Devon E. Reid
IPC分类号： A61B3/14 , A61B3/00 , A61B3/10 , A61B3/107 , A61B5/00 , G01N21/47 , G01B9/02
CPC分类号： A61B3/102 , A61B3/1005 , A61B3/107 , A61B5/0066 , G01B9/0205 , G01B9/02087 , G01B9/02091 , G01N21/4795
摘要： Angle multiplexed optical coherence tomography systems and methods can be used to evaluate ocular tissue and other anatomical structures or features of a patient.
摘要翻译：角度多重光学相干断层扫描系统和方法可用于评估患者的眼组织和其他解剖结构或特征。

8. 发明申请

US20150173604A1 Imaging Probes and Associated Devices, Systems, and Methods Utilizing Electroactive Polymer Actuators 审中-公开
标题翻译：成像探针和相关设备，系统和使用电聚合物致动器的方法
公开(公告)号：US20150173604A1
公开(公告)日：2015-06-25
申请号：US14137252
申请日：2013-12-20
申请人： Novartis AG
发明人： Barry L. Wheatley
IPC分类号： A61B3/10 , A61B5/00
CPC分类号： A61B3/102 , A61B3/1208 , A61B5/0084 , A61B5/066 , G01B9/0205 , G01B9/02091 , G02B6/3624 , G02B23/26 , G02B26/103
摘要： Devices, systems, and methods that utilize electroactive polymer actuators to impart motion to an optical fiber positioned within an imaging probe are provided. In some embodiments, an ophthalmic imaging apparatus comprises an optical probe having a handle sized and shaped for handheld grasping by a user; and a cannula coupled to the handle, the cannula sized and shaped for insertion into an eye to be treated; an optical fiber positioned at least partially within the optical probe, the optical fiber configured to receive an imaging light from an imaging light source and guide the imaging light to an optical element positioned within the cannula of the optical probe; and an actuator system configured to impart motion to the optical fiber, the actuator system including an electroactive polymer (EAP) actuator positioned within the optical probe.
摘要翻译：提供了利用电活性聚合物致动器向位于成像探针内的光纤赋予运动的装置，系统和方法。在一些实施例中，眼科成像设备包括具有尺寸和形状的手柄的光学探针，用于由用户手持握持; 以及联接到所述手柄的套管，所述套管的尺寸和形状用于插入待治疗的眼睛中; 光纤至少部分地位于所述光学探针内，所述光纤被配置为从成像光源接收成像光并将成像光引导到位于所述光学探针的插管内的光学元件; 以及致动器系统，被配置为向所述光纤传递运动，所述致动器系统包括位于所述光学探针内的电活性聚合物（EAP）致动器。

9. 发明授权

US09036966B2 Monolithic beam-shaping optical systems and methods for an OCT probe 有权
标题翻译：整体光束整形光学系统和OCT探针的方法
公开(公告)号：US09036966B2
公开(公告)日：2015-05-19
申请号：US13827234
申请日：2013-03-14
申请人： Corning Incorporated
发明人： Venkata Adiseshaiah Bhagavatula , Klaus Hartkorn , Daniel Max Staloff
IPC分类号： G02B6/32 , A61B5/00 , G01B9/02
CPC分类号： G02B6/32 , A61B5/0066 , G01B9/02034 , G01B9/02035 , G01B9/0205 , G01B9/02091 , Y10T29/4978
摘要： Monolithic beam-shaping optical systems and methods are disclosed for an optical coherence tomography (OCT) probe that includes a transparent cylindrical housing having asymmetric optical power. The system includes a transparent monolithic body having a folded optical axis and at least one alignment feature that supports the end of an optical fiber adjacent an angled planar end wall. The monolithic body also includes a total-internal reflection surface and a lens surface that define object and image planes. Light from the optical fiber end traverses the optical path, which includes the cylindrical housing residing between the lens surface and the image plane. Either the lens surface by itself or the lens surface and the reflective (eg, TIR) surface in combination are configured to substantially correct for the asymmetric optical power of the cylindrical housing, thereby forming a substantially rotationally symmetric image spot at the image plane.
摘要翻译：公开了用于光学相干断层摄影（OCT）探针的整体光束整形光学系统和方法，其包括具有不对称光焦度的透明圆柱形壳体。该系统包括具有折叠光轴的透明单体体和至少一个对准特征，其支撑邻近倾斜的平坦端壁的光纤的端部。单片体还包括全内反射面和限定物体和像面的透镜表面。来自光纤端的光穿过包括位于透镜表面和像平面之间的圆柱形壳体的光路。镜片表面本身或透镜表面以及组合的反射（例如，TIR）表面被配置为基本上校正圆柱形外壳的不对称光焦度，从而在图像平面处形成基本上旋转对称的图像斑点。

10. 发明申请

US20150099984A1 OPTICAL COHERENCE TOMOGRAPHY WITH GRADED INDEX FIBER FOR BIOLOGICAL IMAGING 有权
标题翻译：光学相干光学用于生物成像的等级指数光纤
公开(公告)号：US20150099984A1
公开(公告)日：2015-04-09
申请号：US14400140
申请日：2013-03-15
申请人： AVINGER, INC.
发明人： Manish Kankaria
IPC分类号： G01B9/02 , G02B6/25 , G02B6/255 , A61B5/00
CPC分类号： A61B5/0066 , A61B5/0084 , A61B5/6852 , A61B5/742 , A61B17/3207 , A61B2017/00057 , A61B2017/22094 , A61B2562/0233 , A61M25/09 , G01B9/0205 , G01B9/02057 , G01B9/02091 , G02B6/028 , G02B6/25 , G02B6/255 , Y10T29/49826
摘要： A system for optical coherence tomography includes a source of optical radiation, an optical fiber, and a graded index fiber attached to a distal end of the optical fiber. The optical fiber and the graded index fiber are together configured to provide a common path for optical radiation reflected from a reference interface at a distal end of the graded index fiber and from a target.
摘要翻译：用于光学相干断层摄影的系统包括光学源，光纤和附着到光纤远端的渐变折射率光纤。光纤和分级折射率光纤一起被配置为提供从分级折射率光纤的远端处的参考接口和目标反射的光辐射的公共路径。

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