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1. 发明申请

US20190243117A1 HIGH NUMERICAL APERTURE TELEMICROSCOPY APPARATUS 审中-公开
公开(公告)号：US20190243117A1
公开(公告)日：2019-08-08
申请号：US16151045
申请日：2018-10-03
申请人： THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
发明人： Daniel Fletcher , Wendy Hansen , Neil Switz , David N. Breslauer , Erik Douglas , Robi Maamari , Wilbur Lam , Jesse Dill
IPC分类号： G02B21/36 , H04N5/44 , G01N21/84 , G02B21/02 , H04M1/02 , G02B21/16 , G02B21/00 , G02B21/26 , G02B21/06
CPC分类号： G02B21/361 , G01N21/8483 , G02B21/0008 , G02B21/0092 , G02B21/02 , G02B21/025 , G02B21/06 , G02B21/16 , G02B21/26 , G02B21/36 , G02B21/365 , H04M1/0264 , H04N5/44
摘要： An imaging system consisting of a cell-phone with camera as the detection part of an optical train which includes other components. Optionally, an illumination system to create controlled contrast in the sample. Uses include but are not limited to disease diagnosis, symptom analysis, and post-procedure monitoring, and other applications to humans, animals, and plants.

2. 发明申请

US20190204211A1 SUBSTANCE TESTING SYSTEM AND METHOD 审中-公开
公开(公告)号：US20190204211A1
公开(公告)日：2019-07-04
申请号：US16330005
申请日：2017-09-01
申请人： Alcolizer Pty Ltd
发明人： Roger Alan HUNT , James John BROWN
IPC分类号： G01N21/17 , G01N21/84 , A61B5/00
CPC分类号： G01N21/17 , A61B5/0095 , G01N21/8483 , G01N2021/8908 , G01N2201/0221
摘要： A substance testing method, a substance testing system, and a sensor module for a portable substance testing system is disclosed. The sensor module includes: a light source, configured to illuminate a lateral flow test strip of the portable substance testing system; a filter, comprising a plurality of apertures, configured to filter out light from the lateral flow test strip; and a sensor, for sensing the filtered light, and providing one or more signals indicative of an output of the test strip.

3. 发明申请

US20190153511A1 OPTICAL LENS SYSTEM AND METHOD FOR MICROFLUIDIC DEVICES 审中-公开
公开(公告)号：US20190153511A1
公开(公告)日：2019-05-23
申请号：US16134855
申请日：2018-09-18
申请人： Fluidigm Corporation
发明人： Marc A. Unger , Geoffrey Richard Facer , Barry Clerkson , Christopher G. Cesar , Neil Switz
IPC分类号： C12Q1/686 , G01N21/84 , G01N21/64 , G01N21/75 , G01N27/447 , G02B21/16 , G02B21/36
CPC分类号： C12Q1/686 , B01J2219/00576 , B01J2219/00704 , B01L3/5027 , B01L7/52 , G01N21/64 , G01N21/6452 , G01N21/6456 , G01N21/6486 , G01N21/75 , G01N21/8483 , G01N27/44721 , G01N2021/6421 , G01N2201/061 , G02B21/16 , G02B21/36
摘要： An apparatus for imaging one or more selected fluorescence indications from a microfluidic device. The apparatus includes an imaging path coupled to least one chamber in at least one microfluidic device. The imaging path provides for transmission of one or more fluorescent emission signals derived from one or more samples in the at least one chamber of the at least one microfluidic device. The chamber has a chamber size, the chamber size being characterized by an actual spatial dimension normal to the imaging path. The apparatus also includes an optical lens system coupled to the imaging path. The optical lens system is adapted to transmit the one or more fluorescent signals associated with the chamber.

4. 发明申请

US20190017928A1 EXPLOSIVES DETECTOR AND METHOD FOR DETECTING EXPLOSIVES 审中-公开
公开(公告)号：US20190017928A1
公开(公告)日：2019-01-17
申请号：US16024184
申请日：2018-06-29
申请人： RS DYNAMICS GMBH
发明人： JIRI BLAHA , JAN DUPAC , MICHAL ZÁSTÊRA , ROMAN MÁZL
IPC分类号： G01N21/3504 , G01N21/84 , G01N33/00 , G01N33/22
CPC分类号： G01N21/3504 , G01N1/02 , G01N1/44 , G01N21/76 , G01N21/77 , G01N21/8483 , G01N21/94 , G01N33/0057 , G01N33/227 , G01N2001/022 , G01N2001/028
摘要： An explosives detector includes an infrared sampler having a flat infrared radiation source suitable for release of a solid explosive sample from a surface of a scanned subject using a wavelength of an infrared radiation, and a thermal decomposition unit having a silica glass tube with a silica glass tube gas inlet located in the flat infrared radiation source, wherein the silica glass tube is equipped with a heating element, the thermal decomposition unit being suitable for decomposing the solid explosive sample into a plurality of explosive molecular fragments. The explosives detector further includes a detector cartridge, having a cartridge body with a detection liquid inside, a molecular detection membrane fully submerged under a level of the detection liquid, and a sensing cap, where each explosive molecular fragment is detected by said detector cartridge and a single photon optical detection unit in communication with detector cartridge to provide a data stream indicative of explosive molecular fragment's presence in the solid explosive sample.

5. 发明申请

US20180313829A1 Progressive compression driven flow cartridge for analyte detecting strip and method 审中-公开
公开(公告)号：US20180313829A1
公开(公告)日：2018-11-01
申请号：US15769715
申请日：2016-10-19
申请人： DNT SCIENTIFIC RESEARCH, LLC
发明人： Naishu Wang , David F. Zhou
IPC分类号： G01N33/543 , G01N33/569 , G01N21/78
CPC分类号： G01N33/54386 , G01N21/78 , G01N21/8483 , G01N33/558 , G01N33/56983 , G01N2021/7759
摘要： A cartridge (1) and method for conducting a labeled molecular affinity binding test such as antibody/antigen, ligand/receptor, and colorometric reactions, and other chemical reactions for which one or more analytes is present in a liquid sample formate. A progressive compression structure (22,36) progressively forces a liquid flow out of a conjugate pad (26) toward a reaction region (27) to more thoroughly and rapidly mix the liquid, encouraging specific first affinity binding to the analytes in question. A specially dimensioned constricting passageway (35) surrounding the reaction region including the result zones (28,29) provides an additional siphoning force to the flow. These combined forces rapidly and more evenly guide the flow of liquid through the reaction region so that the rushed rate of uptake of analytes at the strip lines are more evenly distributed, adhesive attachment of non-specific molecules is largely avoided, vastly improving sensitivity and specificity, and providing quantitative results in some tests.

6. 发明申请

US20180260775A1 ASSAY DEVICE 审中-公开
公开(公告)号：US20180260775A1
公开(公告)日：2018-09-13
申请号：US15751065
申请日：2016-08-19
申请人： Molecular Vision Limited
发明人： Chris Hand , Oliver Hofmann , Gihan Ryu , Miguel Ramon , Neeraj Adsul
IPC分类号： G06Q10/08
CPC分类号： G06Q10/0832 , G01N21/8483 , G01N2021/8488
摘要： A computer system and method is provided to filter clearance sensor data output by a sensor system during a load/offload procedure of a first object relative to a second object. A processing device of the computer system is configured to access hard threshold data, unique threshold data, and sensor data output by the sensor system sensing aspects of the load/offload procedure. The processing device is further configured to determine whether the sensor data exceeds the unique threshold, determine whether the sensor data that is determined to exceed the unique threshold is voidable data related to a noncritical event, and generate filtered sensor data that includes modifications to the voidable data.

7. 发明申请

US20180259500A1 ELECTRONIC ANALYTE ASSAYING DEVICE 审中-公开
公开(公告)号：US20180259500A1
公开(公告)日：2018-09-13
申请号：US15977829
申请日：2018-05-11
申请人： Church & Dwight, Co., Inc.
发明人： Andy Sturman , Benedict Zin , Albert Nazareth , Henry Bell
IPC分类号： G01N33/487 , G01N33/68 , G01N21/84 , G01N33/76 , G01N21/17 , G01N33/62 , G01N33/493
CPC分类号： G01N33/48792 , G01N21/17 , G01N21/8483 , G01N33/48785 , G01N33/493 , G01N33/62 , G01N33/689 , G01N33/76 , G01N2201/062 , G01N2201/12 , G01N2333/59
摘要： An improved electronic diagnostic device for detecting the presence of an analyte in a fluid sample comprises a casing having a display, a test strip mounted in the casing, a processor mounted in the casing, and a first sensor mounted in the casing and operatively coupled to the processor. The processor is configured to receive a signal from the first sensor when the device is exposed to ambient light thereby causing the device to become activated. The device includes a light shield that exerts pressure across a width of the test strip to prevent fluid channeling along the length of the test strip. The processor is configured to present an early positive test result reading when a measured value exceeds a predetermined early reading threshold value at any time after a predetermined early testing time period.

8. 发明授权

US10073092B2 Apparatus for assay strip(s) with specimen loading to multiple zones and related methods 有权
公开(公告)号：US10073092B2
公开(公告)日：2018-09-11
申请号：US15047974
申请日：2016-02-19
申请人： Andrew Wang
发明人： Andrew Wang
IPC分类号： G01N33/558 , G01N33/543 , G01N21/78 , G01N21/84 , G01N21/77
CPC分类号： G01N33/558 , G01N21/78 , G01N21/8483 , G01N2021/7759
摘要： A lateral flow assay device that is defined by multiple loading zones, wherein a sample pad is located before and upstream from a conjugate pad and another sample pad is located after and downstream from the conjugate pad. This configuration allows for increased sensitivity for detecting an analyte in a specimen. The device may employ multiple collection pads or a single collection pad and the collection pads may be engaged with the sample pads in several manners, including but not limited to, pressing down on a cassette with collection pads onto a cassette with the test strips, or by sliding the collection pads along the cassette with the test strips and sample pads.

9. 发明申请

US20180234633A1 Remote Analyte Testing System 审中-公开
公开(公告)号：US20180234633A1
公开(公告)日：2018-08-16
申请号：US15955233
申请日：2018-04-17
申请人： Invent.ly LLC
发明人： Stephen J. Brown
IPC分类号： H04N5/232 , H04N7/18 , G16H10/40 , G01N21/84
CPC分类号： H04N5/23293 , G01N21/8483 , G01N2201/12 , G06F19/3418 , G16H10/40 , G16H40/67 , H04N5/23206 , H04N7/18
摘要： A system has a test apparatus comprising a test medium having a machine-readable identifier, the medium enabled to accept an analyte for a specific test, a smart telephone or a pad device having imaging apparatus, a digital memory, input apparatus providing recording of contextual information associated with a specific test, and first coded instructions providing integration of images and contextual information associated with a specific test into a specific data structure, a network-connected server having a processor and coupled to at least one server-side data repository, and second coded instructions executing on the processor of the server from a non-transitory medium. A user applies the analyte, allows the test to proceed to conclusion, and initiates at least one image capture by the imaging apparatus.

10. 发明申请

US20180231464A1 ASSAY DEVICE 审中-公开
公开(公告)号：US20180231464A1
公开(公告)日：2018-08-16
申请号：US15751074
申请日：2016-08-19
申请人： Molecular Vision Limited
发明人： Chris Hand , Oliver Hofmann , Gihan Ryu , Miguel Ramon , Dene Baldwin
IPC分类号： G01N21/64 , G01N21/84 , G01N33/558 , G01N21/78
CPC分类号： G01N21/645 , G01N21/6428 , G01N21/78 , G01N21/8483 , G01N33/558 , G01N2021/6439 , G01N2021/7786 , G01N2201/0628
摘要： An assay device for the quantitative determination of the concentration of at least one analyte in a liquid sample comprises a planar emitter (2), a planar detector (3), a lateral flow membrane (4) interposed between the emitter (2) and the detector (3), a conjugate pad (5) in fluid communication with a proximal end of the lateral flow membrane (4), the conjugate pad (5) comprising optically detectable tagging particles bound to a first assay component, a sample pad (6) in fluid communication with the conjugate pad (5) and arranged to receive the liquid sample, and a wicking pad (7) in fluid communication with a distal end of the lateral flow membrane (4). The lateral flow membrane (4) is formed from a light transmissive material and is capable of transporting fluid from the conjugate pad (5) to the wicking pad (7) by capillary action. The lateral flow membrane (4) comprises at least one test region (8, 12) comprising an immobilised second assay component for retaining the tagging particles in the test region (8, 12) in dependence on the binding between the analyte, the first assay component and the second assay component in order to generate a concentration of tagging particles in the test region (8, 12) that is indicative of the concentration of the analyte in the liquid sample. The emitter (2) comprises an emission layer (9, 16) of an organic electroluminescent material and the emission layer (9, 16) is aligned with the test region (8, 12) of the lateral flow membrane 4, whereby the emitter (2) is capable of illuminating the test region (8, 12). The detector (3) comprises an absorption layer (10, 15) of an organic photovoltaic material and the absorption layer (10, 15) is aligned with the test region (8, 12) of the lateral flow membrane 4, whereby the detector (3) is capable of detecting light from the test region (8, 12).

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