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1. 发明申请

US20230124965A1 PLANT COMPOSITION, TRADITIONAL CHINESE MEDICINE COMPOSITION AND USE THEREOF 有权
公开(公告)号：US20230124965A1
公开(公告)日：2023-04-20
申请号：US18047697
申请日：2022-10-19
申请人： NATIONAL RESEARCH INSTITUTE OF CHINESE MEDICINE, MINISTRY OF HEALTH AND WELFARE
发明人： YI-CHANG SU , WEN-HUI CHIOU , YUH-CHIANG SHEN , WEN-CHI WEI , KENG-CHANG TSAI , CHIA-CHING LIAO , YU-HWEI TSENG , CHUN-TANG CHIOU , YU-CHI LIN , LI-HSIANG WANG
IPC分类号： A61K36/714 , A61K36/8969 , A61K36/076 , A61K36/8888 , A61K36/282 , A61K36/539 , A61K36/428 , A61K36/575 , A61K36/78 , A61K36/484 , A61P11/00
摘要： The present invention relates to a plant composition, a traditional Chinese medicine composition and use thereof. The plant composition comprises Prepared Monkshood Daughter Root (Aconitum carmichaelii), Fragrant Solomonseal Rhizome (Polygonatum odoratum), Indian Bread (Poria cocos), Pinellia tuber (Pinellia ternata), Oriental Wormwood Herb (Artemisia scoparia), Scutellaria Root (Scutellaria baicalensis), Mongolian Snakegourd Fruit (Trichosanthes kirilowii), Magnolia Bark (Magnolia officinalis), Heartleaf Houttuynia Herb (Houttuynia cordata) and Baked Licorice Root and Rhizome (Glycyrrhiza glabra), which is used as a traditional Chinese medicine composition. In addition, the traditional Chinese medicine composition can be used to treat pulmonary embolism or pulmonary fibrosis.

2. 发明申请

US20230122849A1 USE OF PLANT COMPOSITION, TRADITIONAL CHINESE MEDICINE COMPOSITION IN PREPARING MEDICINE FOR TREATING COVID-19 有权
公开(公告)号：US20230122849A1
公开(公告)日：2023-04-20
申请号：US18047712
申请日：2022-10-19
申请人： NATIONAL RESEARCH INSTITUTE OF CHINESE MEDICINE, MINISTRY OF HEALTH AND WELFARE
发明人： YI-CHANG SU , WEN-HUI CHIOU , YUH-CHIANG SHEN , WEN-CHI WEI , KENG-CHANG TSAI , CHIA-CHING LIAO , YU-HWEI TSENG , CHUN-TANG CHIOU , YU-CHI LIN , LI-HSIANG WANG , CHIEN-HSIEN HUANG , CHIA-MO LIN , CHI-KUEI LIN , YI-CHIA HUANG , CHIEN-JUNG LIN , JUI-SHAN LIN , YA-SUNG YANG , CHUN-HSIANG CHIU , SHUN-PING CHENG , HSIEN-HWA KUO , WU-PU LIN , CHEN-SHIEN LIN , BO-CHENG LAI , YUAN-NIAN HSU , TSUNG-LUNG TSAI , WEI-CHEN HSU , TIENG-SIONG FONG , YI-WEN HUANG , CHIA-I TSAI , YA-CHEN YANG , MING-CHE TSAI , MING-HUEI CHENG , SHIH-WEI HUANG
IPC分类号： A61K36/714 , A61K36/704 , A61K36/076 , A61K36/8888 , A61K36/282 , A61K36/539 , A61K36/428 , A61K36/575 , A61P31/14
摘要： The present invention relates to a method of treating moderate or severe symptoms of COVID-19 using a plant composition. The plant composition comprises Prepared Monkshood Daughter Root (Aconitum carmichaelii), Fragrant Solomonseal Rhizome (Polygonatum odoratum), Indian Bread (Poria cocos), Pinellia tuber (Pinellia ternata), Oriental Wormwood Herb (Artemisia scoparia), Scutellaria Root (Scutellaria baicalensis), Mongolian Snakegourd Fruit (Trichosanthes kirilowii), Magnolia Bark (Magnolia officinalis), Heartleaf Houttuynia Herb (Houttuynia cordata), and Baked Licorice Root and Rhizome (Glycyrrhiza glabra), which is used as a traditional Chinese medicine composition.

3. 发明授权

US09498508B2 Pharmaceutical composition for treating cancers and preparation method therefor 有权
公开(公告)号：US09498508B2
公开(公告)日：2016-11-22
申请号：US14846786
申请日：2015-09-06
申请人： Mingchun Xiao
发明人： Mingchun Xiao
IPC分类号： A01N65/00 , A61K36/9068 , A61K36/752 , A61K36/804 , A61K36/85 , A61K36/884 , A61K36/888 , A61K36/8884 , A61K36/8888 , A61K36/8945 , A61K36/8988 , A61K36/8998 , A61K36/9062 , A61K36/9064 , A61K36/9066 , A61K36/46 , A61K36/481 , A61K36/484 , A61K36/53 , A61K36/54 , A61K36/575 , A61K36/68 , A61K36/71 , A61K36/714 , A61K36/734 , A23F3/16 , A61K36/076 , A61K36/232 , A61K36/233 , A61K36/284 , A61K36/48 , A61K36/482 , A61K36/532 , A61K36/535 , A61K36/538 , A61K36/539 , A61K36/65 , A61K36/66 , A61K36/88 , A61K36/8905 , A61K36/906 , A61K36/07 , A61K36/12 , A61K36/185 , A61K36/21 , A61K36/236 , A61K36/237 , A61K36/258 , A61K36/268 , A61K36/515 , A61K36/882
CPC分类号： A61K36/9068 , A23F3/163 , A61K36/07 , A61K36/076 , A61K36/12 , A61K36/185 , A61K36/21 , A61K36/232 , A61K36/233 , A61K36/236 , A61K36/237 , A61K36/258 , A61K36/268 , A61K36/284 , A61K36/46 , A61K36/48 , A61K36/481 , A61K36/482 , A61K36/484 , A61K36/515 , A61K36/53 , A61K36/532 , A61K36/535 , A61K36/538 , A61K36/539 , A61K36/54 , A61K36/575 , A61K36/65 , A61K36/66 , A61K36/68 , A61K36/71 , A61K36/714 , A61K36/734 , A61K36/752 , A61K36/804 , A61K36/85 , A61K36/88 , A61K36/882 , A61K36/884 , A61K36/888 , A61K36/8884 , A61K36/8888 , A61K36/8905 , A61K36/8945 , A61K36/8988 , A61K36/8998 , A61K36/906 , A61K36/9062 , A61K36/9064 , A61K36/9066 , A61K2300/00
摘要： A pharmaceutical composition for treating cancers and preparation method thereof. Said composition for treating cancers contains Chinese medicinal materials including Rhizoma Pinelliae, Rhizoma Arisaematis, Rhizoma Gastrodiae etc., and said preparation method is in accordance with a conventional Chinese medicinal preparation method, manufacturing said composition to form any one of the ordinary oral preparations.

4. 发明授权

US09119871B1 Method for treating cerebral edema or complication thereof 有权
标题翻译：治疗脑水肿或并发症的方法
公开(公告)号：US09119871B1
公开(公告)日：2015-09-01
申请号：US14281948
申请日：2014-05-20
申请人： Chen-Yu Lee
发明人： Chen-Yu Lee , Da-Tong Ju , Hsing-Lung Chao , Shih-Fang Chung , Hsin-I Ma , Yee-Min Jen
IPC分类号： A61K36/00 , A61K36/233 , A61K36/539 , A61K36/8888 , A61K36/25 , A61K36/8988 , A61K36/754 , A61K36/236 , A61K36/537 , A61K36/284 , A61K36/076 , A61K36/725 , A61K36/708 , A61K36/752 , A61K36/258 , A61K36/65
CPC分类号： A61K36/752 , A61K36/076 , A61K36/233 , A61K36/236 , A61K36/25 , A61K36/258 , A61K36/284 , A61K36/537 , A61K36/539 , A61K36/65 , A61K36/708 , A61K36/725 , A61K36/754 , A61K36/8888 , A61K36/8988 , A61K2300/00
摘要： A method for treating cerebral edema or complications thereof is disclosed. The method comprises administering a herbal medicinal composition to a subject in need, wherein the herbal medicinal composition comprises 1.3-5.3 parts by weight of Chaihu, 2.2-8.8 parts by weight of Hunagqing, 1.8-7.0 parts by weight of Panxia, 1.8-7.0 parts by weight of Chishaoyao, 0.5-1.8 parts by weight of Dahuang, 1.3-5.3 parts by weight of Zhishi, 2.2-8.8 parts by weight of Hungtsao, 4.4-17.5 parts by weight of Fuling, 1.8-7.0 parts by weight of Chuling, 2.2-8.8 parts by weight of Zerxie, 1.8-7.0 parts by weight of Changchu, 1.3-5.3 parts by weight of Mahuang, 1.8-7.0 parts by weight of Dansheng, 2.2-8.8 parts by weight of Chuanxiong, 2.2-8.8 parts by weight of Wuchuyu, 2.2-8.8 parts by weight of Tienma, 1.3-5.3 parts by weight of Ginseng, and 1.3-5.3 parts by weight of Chuanchi.
摘要翻译：公开了治疗脑水肿或其并发症的方法。该方法包括向需要的受试者施用草药组合物，其中所述草药组合物包含柴胡1.3-5.3重量份，Hun格青2.2-8.8重量份，潘夏1.8-7.0重量份，1.8-7.0重量份柴达奥重量份，大黄0.5-1.8重量份，志氏1.3-5.3重量份，红枣2.2-8.8重量份，F陵4.4-17.5重量份，ul陵1.8-7.0重量份，Zerxie 2.2-8.8重量份，Changchu 1.8-7.0重量份，Mahuang 1.3-5.3重量份，Dansheng 1.8-7.0重量份，Chuanxiong 2.2-8.8重量份，2.2-8.8重量份的武修玉，天津2.2-8.8重量份，人参1.3-5.3重量份，川崎1.3-5.3重量份。

5. 发明授权

US6077512A Externally-applied medicine for curing black foot disease 失效
标题翻译：外用药治疗黑脚病
公开(公告)号：US6077512A
公开(公告)日：2000-06-20
申请号：US497169
申请日：1995-06-30
申请人： Ren-Rong Chen
发明人： Ren-Rong Chen
IPC分类号： A61K31/045 , A61K33/22 , A61K36/324 , A61K36/328 , A61K36/48 , A61K36/61 , A61K36/756 , A61K36/8884 , A61K36/8888 , A61K36/898 , A61K35/78
CPC分类号： A61K36/328 , A61K31/045 , A61K33/22 , A61K36/324 , A61K36/48 , A61K36/61 , A61K36/756 , A61K36/8884 , A61K36/8888 , A61K36/898 , Y10S514/887
摘要： An externally-applied medicine for curing black foot disease comprising a basis part consisting of equal amount of ground, powdered, and mixed clove, frankincense, myrrha, rhizama arisaematis, pinellia, monkshood (root) or kusnezoff monkshood (root), and tuber of bamboo-leaved orchid, and an adjuvant part consisting of equal amount of round, powdered, and mixed borneol, powdered soy bean, borax, coptis root and/or phellodendron amureuse, and sepia aculeata. The medicine is used in such a manner that the powdered basis part is mixed and stirred with tea water until it becomes plaster-like, and the adjuvant part is scattered in dry form onto the wound or swollen area caused by the black foot disease before the plaster-like basis part is applied to the wound or swollen area about 0.5 cm in thickness. The wound is then bandaged and the medicine is renewed once to twice a day until fresh flesh appears in the wound. Thereafter, the medicine is continuously applied but in a dry form until the wound is completely healed.
摘要翻译：一种用于治疗黑脚病的外用药物，包括由等量的地面，粉末和混合丁香，乳香，没药，根瘤菌，针茅，僧侣（根）或kusnezoff僧侣（根）组成的基础部分和块茎竹叶兰，以及由等量的圆形，粉状和混合的冰片，粉状大豆，硼砂，黄连根和/或黄柏香草和乌贼属组成的辅助部分。该药物的使用方法是将粉末状基础部分与茶水混合搅拌直至变成石膏状，并且佐剂部分以干燥形式散布到由黑脚病引起的伤口或肿胀部位石膏状基础部位适用于约0.5cm厚的伤口或肿胀区域。伤口然后被包扎，药物每天更新一次，直到新鲜的肉出现在伤口中。此后，药物被连续施用，但以干燥形式直到伤口完全愈合。

6. 发明申请

US20200297794A1 METHOD FOR EXTRACTION OF CHINESE HERBAL MEDICINE USING SMALL MOLECULE MICRO-SHEAR TECHNOLOGY 审中-公开
公开(公告)号：US20200297794A1
公开(公告)日：2020-09-24
申请号：US16089379
申请日：2016-04-28
申请人： Jian MA
发明人： Jian MA
IPC分类号： A61K36/634 , A61K36/258 , A61K36/8888
摘要： A method for extraction of Chinese herbal medicines using a small molecule micro-shear technology, including: pretreating, jet milling, grinding, pulverizing, cell-wall breaking, and extraction of Chinese herbal medicines, so that the raw material can be fully utilized. Herbs are cut into small molecule substances, which is easy to be absorbed by the means of a superfine grinding technology and a cell-wall breaking technology. By means of a supercritical carbon dioxide extraction technology, active ingredients in Chinese herbal medicines can be efficiently and singly extracted, and organic solvent residues in the raw herbs can be removed.

7. 发明申请

US20190201472A1 Method Of Independent or Adjuvant Treatment Of Parkinson's Disease and Parkinson's Syndrome 审中-公开
公开(公告)号：US20190201472A1
公开(公告)日：2019-07-04
申请号：US15859983
申请日：2018-01-02
申请人： Chen-Yu LEE
发明人： Chen-Yu LEE , Che-Hao WU , Yao-Nan YUAN , Chuang-Hsin CHIU , Yan-Chih LIAO , Yu-Ming FAN , Yuan-Hao CHEN , Dueng-Yuan HUENG
IPC分类号： A61K36/8888 , A61K36/076 , A61K36/484 , A61K36/284 , A61K36/884 , A61K36/752 , A61K36/8998 , A61K36/9068 , A61K36/756 , A61K36/8988 , A61K36/714 , A61K36/232 , A61K36/481 , A61P25/16
CPC分类号： A61K36/8888 , A61K36/076 , A61K36/232 , A61K36/284 , A61K36/481 , A61K36/484 , A61K36/714 , A61K36/752 , A61K36/756 , A61K36/884 , A61K36/8988 , A61K36/8998 , A61K36/9068 , A61P25/16
摘要： The present invention is directed to a therapeutic method of independent or adjuvant treatment of Parkinson's disease and Parkinson's syndrome, comprising administering to a subject in need a therapeutically effective amount of Chinese medicine composition, wherein the Chinese medicine composition comprises the extract of the mixture of Rhizoma Pinelliae, Rhizoma Atractylodis Macrocephalae, Poria, Radix Glycyrrhizae, Rhizoma Atractylodis, Rhizoma Alismatis, Pericarpium Citri Reticulatae, Massa Medicata Fermentata, Fructus Hordei Germinatus, Rhizoma Zingiberis, Cortex Phellodendri, rhizoma Gastrodiae, Radix Aconiti Lateralis Praeparata, Radix Angelicae Sinensis, and Radix Astragali.

8. 发明申请

US20080089906A1 Use of substances to protect FGF-2 or FGF-beta growth factor 有权
标题翻译：使用物质保护FGF-2或FGF-β生长因子
公开(公告)号：US20080089906A1
公开(公告)日：2008-04-17
申请号：US11803805
申请日：2007-05-16
申请人： Delphine Rival , Sebastien Bonnet , Isabelle Orly , Eric Perrier
发明人： Delphine Rival , Sebastien Bonnet , Isabelle Orly , Eric Perrier
IPC分类号： A61K8/97 , A61K36/00 , A61K36/03 , A61K36/31 , A61P17/00 , G01N33/53 , A61Q19/00 , A61K36/815 , A61K36/8888 , A61K36/8998
CPC分类号： A61K8/97 , A61K36/185 , A61K36/31 , A61K36/8998 , A61K2800/91 , A61Q1/06 , A61Q5/02 , A61Q19/00 , A61Q19/04 , A61Q19/08 , A61Q19/10 , G01N33/557 , G01N2333/503 , G01N2500/04
摘要： The invention relates to substances which are capable of protecting FGF-2, to a composition for preventing or controlling degradation of FGF-2, and a method of protecting FGF-2 in the skin from degradation.In particular, the invention relates to an extract of Hibiscus Abelmoschus or ambrette, a rebokza extract, a gougizi berry extract, a banha extract, a lessonia extract, a mustard flour extract, a wooyin extract, a barley extract, and/or a sesame extract, in amounts effective to protect FGF-2 from its degradation.Further, the present invention allows the extracellular matrix to be restructured, particularly at the dermis, which is useful, for example, for controlling aging.
摘要翻译：本发明涉及能够保护FGF-2的物质，用于预防或控制FGF-2降解的组合物，以及保护皮肤中FGF-2的降解方法。特别地，本发明涉及芙蓉芙蓉提取物或胭脂红提取物，雷贝提取物，甘草提取物，巴拿马提取物，皂甙提取物，芥子提取物，维生素提取物，大麦提取物和/或芝麻的提取物。提取物，有效保护FGF-2免于其降解。此外，本发明允许细胞外基质重组，特别是在真皮上，其可用于例如控制老化。

9. 发明授权

US06916494B2 Anti-hemorrhoid composition and process for its manufacture 失效
标题翻译：抗痔疮组合物及其制造方法
公开(公告)号：US06916494B2
公开(公告)日：2005-07-12
申请号：US10274267
申请日：2002-10-21
申请人： Chan Sik Park
发明人： Chan Sik Park
IPC分类号： A61K33/00 , A61K36/17 , A61K36/258 , A61K36/40 , A61K36/484 , A61K36/534 , A61K36/65 , A61K36/708 , A61K36/714 , A61K36/756 , A61K36/8888 , A61K45/06 , A61K35/78
CPC分类号： A61K36/8888 , A61K33/00 , A61K36/17 , A61K36/258 , A61K36/40 , A61K36/484 , A61K36/534 , A61K36/65 , A61K36/708 , A61K36/714 , A61K36/756 , A61K45/06 , Y10S514/882 , A61K2300/00
摘要： The composition and process for preparing an anti-hemorrhoid composition which comprises providing a predetermined effective amount of natural substances of the genera Glycyrrhizae Radix, Testudinis Carapax, Cervi Parvum Cornu, Rhei Rhizoma, Ephedrae Herba, Natrii Sulfas, Moutan Radicis Cortex, Menthae Herba, Pinelliae Rhizoma, Pasoniae Radix, Acontii Tuber, Corni Fructus, Gypsum, Ginseng Radix, Cinnabaris, Talcum and Pelladendri Radix in an aqueous medium to form an initial mixture, extracting the initial mixture with water at a temperature of about 70°-80° C. for 1-2 hours to produce an aqueous mixture, filtering the aqueous mixture to produce a filtrate, and evaporating the filtrate to a moisture content of 30% to produce an extract which can be used as a treatment for hemorrhoid diseases.
摘要翻译：一种制备抗痔疮组合物的组合物和方法，其包括提供预定有效量的甘草，，ax，vi u，莱氏根，麻黄，纳氏沙门氏菌，芒of草， Pinelliae Rhizoma，Pasoniae Radix，Acontii Tuber，Corni Fructus，Gypsum，Ginseng Radix，Cinnabaris，Talcum and Pelladendri Radix在水性介质中形成初始混合物，在约70°-80°C的温度下用水萃取初始混合物处理1-2小时以制备含水混合物，过滤含水混合物以产生滤液，并将滤液蒸发至含水量为30％，以产生可用作治疗痔疮疾病的提取物。

10. 发明授权

US5055297A Immunopotentiator 失效
标题翻译：免疫增强剂
公开(公告)号：US5055297A
公开(公告)日：1991-10-08
申请号：US254772
申请日：1988-09-21
申请人： Michio Fujimaki , Shojiro Ikematsu , Masao Hada , Hidetaka Fukue , Katsuhiro Fukutake
发明人： Michio Fujimaki , Shojiro Ikematsu , Masao Hada , Hidetaka Fukue , Katsuhiro Fukutake
IPC分类号： A61K36/23 , A61K36/258 , A61K36/28 , A61K36/48 , A61K36/539 , A61K36/8888 , A61K36/9068
CPC分类号： A61K36/48 , A61K36/23 , A61K36/258 , A61K36/28 , A61K36/539 , A61K36/8888 , A61K36/9068 , Y10S514/885
摘要： An immunopotentiator for patients with viruses of an acquired immune deficiency syndrome, which contains Sho-saiko-to (Xiao-Chai-Hu-Tang) or Ninzin-to (Ren-Shen-Tang). Sho-saiko-to (Xiao-Chai-Hu-Tang) or Ninzin-to (Ren-Shen-Tang) according to the formulations of Chinese medicine, is used in situ or in the form of a preparation.
摘要翻译： PCT No.PCT / JP88 / 00199 Sec。 371日期：1988年9月21日 102（e）1988年9月21日PCT PCT日期：1988年2月25日。对于获得性免疫缺陷综合征病毒的患者的免疫增强剂，其含有Sho-saiko-to（Xiao-Chai-Hu-Tang）或Ninzin- （任沉棠）。根据中药制剂，肖氏子（小柴胡塘）或宁津至（任沉堂）原位或以制剂的形式使用。

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