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1. 发明授权

US11633548B2 Drug injection device with visual and audio indicators 有权
公开(公告)号：US11633548B2
公开(公告)日：2023-04-25
申请号：US15930018
申请日：2020-05-12
申请人： AMGEN INC.
发明人： Peter V. Shultz , Christopher R. Folk , Sigrid Moeslinger , Masamichi Udagawa , Molly Evans , Lin Gao , Lisa Nugent
IPC分类号： A61M5/32 , A61M5/50 , A61B50/33 , A61M5/31
摘要： A drug injection device (10) including a housing (12) for holding a container (20) having a needle (24) for penetrating skin and a plunger (42) for expelling a drug stored in the container. The device includes visual and/or audible indicators for indicating that the correct depth of needle penetration has been achieved and that drug injection/extrusion has been started and/or completed. The device may further include a label (140) for visually confirming the quality of the drug contained therein. Alternatively, a tray (110) may be provided for receiving the drug injection device, which allows the quality of the drug contained therein to be visually confirmed.

2. 发明申请

US20230098606A1 DEVICES AND METHODS FOR ASSISTING A USER OF A DRUG DELIVERY DEVICE 有权
公开(公告)号：US20230098606A1
公开(公告)日：2023-03-30
申请号：US17940422
申请日：2022-09-08
申请人： AMGEN INC.
发明人： Adam B. McCullough , Basel Hasan Taha , Jimmie L. Ward , Steven William Badelt , Ferry Tamtoro , Huaying Yang , Mark Ka Lai Lee , Desheng Yin , Scott R. Gibson , Donald Busby , Peter V. Shultz , Keith P. Kogler
IPC分类号： A61M5/20 , A61M5/315 , A61M5/32 , A61M5/142 , A61M5/50 , G16H20/17 , G16H40/63 , G16H40/00 , G16H40/67 , G06Q50/22 , G06Q50/00 , A61M5/158 , A61M5/24
摘要： Devices and methods are disclosed for assisting a user of a drug delivery device with an application executing on a mobile computing device. The mobile computing device may receive information from the drug delivery device related to its condition and/or operation and subsequently select an informational and/or instructional prompt to be displayed to the user based on the received information. The mobile computing device may also generate a display in the application including the selected informational prompt and/or the instructional prompt. Accordingly, the user of the drug delivery device can be guided through the drug delivery process in real time, thereby reducing the likelihood of improper or incomplete use of the drug delivery device.

3. 发明授权

US11612729B2 Implant injection device provided with sequentially released pushing means 有权
公开(公告)号：US11612729B2
公开(公告)日：2023-03-28
申请号：US16388275
申请日：2019-04-18
申请人： Nemera La Verpillière
发明人： Gaëtan Painchaud , Pascal Dugand , Thomas Megard
IPC分类号： A61M37/00 , A61M5/32 , A61M5/50 , A61B17/34
摘要： An implant injection device includes an injection needle, a receiver housing receiving at least a first implant and a second implant, an injection mechanism, including a pushing rod arranged upstream from the implants and configured to push the implants through the injection needle between an initial position and a final position in which the implants are injected, a pushing device for pushing on the pushing rod, configured to exert a force to move the pushing rod from the initial position to the final position, an intermediate stop device holding the pushing rod in an intermediate position and opposing the force exerted by the pushing device when a stroke of the pushing rod reaches a predetermined distance corresponding to a length of injection of the first implant, and an actuator for actuation by a user, configured to release the pushing rod from the intermediate position to the final position.

4. 发明授权

US11602597B2 Prefilled syringe with breakaway force feature 有权
公开(公告)号：US11602597B2
公开(公告)日：2023-03-14
申请号：US16591169
申请日：2019-10-02
申请人： Antares Pharma, Inc.
发明人： James W. Lannan , Julius C. Sund
IPC分类号： A61M5/20 , A61M5/50 , A61M5/32
摘要： A jet injector that includes a prefilled syringe. The syringe includes a fluid chamber that contains a medicament. The syringe also has an injection-assisting needle, and a plunger is movable within the fluid chamber. A housing is configured for allowing insertion of the needle to a penetration depth. The housing includes a retractable guard and an interference component, e.g., a lock ring, adjacent to the retractable guard that interferes with the movement of the retractable guard. An energy source is configured for biasing the plunger to produce an injecting pressure to jet inject the medicament from the fluid chamber through the needle to an injection site.

5. 发明申请

US20230051213A1 DRUG CONTAINER SYSTEMS INCLUDING LOCK-OUT MECHANISMS 有权
公开(公告)号：US20230051213A1
公开(公告)日：2023-02-16
申请号：US17796006
申请日：2021-01-29
申请人： Eli Lilly and Company
发明人： Jaime Ray ARNETT
IPC分类号： A61M5/00 , A61M5/50
摘要： A drug delivery system includes a drug delivery device that carries and delivers a drug. The system further includes a housing, and the housing includes a main body and a cover coupled to the main body. The main body includes a chamber that carries the drug delivery device and an opening coupled to the chamber. The cover is movable relative to the main body from a closed position to an open position. In the closed position the cover obscures the opening and thereby inhibits egress of the drug delivery device from the chamber via the opening, and in the open position the cover permits egress of the drug delivery device from the chamber via the opening. A lock-out mechanism is carried by the housing. The lock-out mechanism inhibits the cover from returning to the closed position after moving to the open position.

6. 发明申请

US20230049720A1 METHOD OF SEALING A SYRINGE BARREL 有权
公开(公告)号：US20230049720A1
公开(公告)日：2023-02-16
申请号：US17967482
申请日：2022-10-17
申请人： KAIRISH INNOTECH PRIVATE LIMITED
发明人： Pratul Prakash Potdar , Anil Narayan Narvekar
IPC分类号： A61M5/32 , A61M5/31 , A61M5/50 , A61M5/24 , A61J1/14 , A61M5/34
摘要： Disclosed is a method of sealing a syringe barrel having a syringe tip with a collar. The syringe tip is sealed with a resilient closure. A tamper evident syringe tip cap comprising a cap member and a sleeve member separated by an annular first breaking line is then pushed over the resilient closure, to couple the proximal end of the sleeve member with the collar. The distal end of the resilient closure is accommodated in the cap member and protrudes beyond the sleeve member. The first breaking line is bridged by a coupling strip. For use of the syringe and providing access to the closure, the first breaking line is broken by pivoting the cap member away. The sleeve member remains coupled to the collar. Further tearing the cap member downward causes breaking a second breaking line provided in the sleeve member, thereby enabling removing the entire syringe tip cap.

7. 发明申请

US20230019806A1 Auto-Injector 有权
公开(公告)号：US20230019806A1
公开(公告)日：2023-01-19
申请号：US17952801
申请日：2022-09-26
申请人： Sanofi-Aventis Deutschland GMBH
发明人： Yannick Hourmand , Timothy Donald Barrow-Williams , Matthew Ekman
IPC分类号： A61M5/20 , A61M5/50
摘要： According to the invention, an auto-injector for administering a dose of a liquid medicament (M) comprises of a substantially cylindrical housing arranged to contain a pre-filled syringe filled with the medicament (M), a needle shroud slibably arranged with respect to the housing and adapted to rest on the skin of a patient receiving an injection, a releasable drive means arranged within the housing that is capable of, upon release, translating the needle shroud in a proximal direction (P) towards a safe position (PS) and a rotating collar rotatably arranged within the housing. The needle shroud in the safe position (PS) surrounds the injection needle after the injection has been carried out. The rotating collar engages the needle shroud in a manner that forces the rotating collar to rotate within the housing when the needle shroud is translated in the proximal direction (P).

8. 发明申请

US20220401655A1 PLUNGER ROD AND SYRINGE ADAPTED FOR COMPRESSION FAILURE 有权
公开(公告)号：US20220401655A1
公开(公告)日：2022-12-22
申请号：US17773713
申请日：2020-11-05
申请人： KRUI Medical AB
发明人： Per KNUTSSON
IPC分类号： A61M5/315 , A61M5/50
摘要： A plunger rod (104) for use in connection with a syringe barrel (102) is provided. The plunger rod (104) comprises a distal plunger top (105), having a proximal bottom surface (113), and a proximal elongated shaft (106) comprising a proximal end (107a) adapted to receive an applied force along an axis (1000) and a distal end plate (107b) adapted to transmit said applied force along said axis (1000). The plunger rod (104) is adapted to be inserted into the barrel (102) of a syringe (100) extending along the axis (1000). The distal plunger top (105) and the proximal elongated shaft (106) are connected to each other by a releasable connection (115). The releasable connection (115) comprises: distal top rupture means (116) comprising at least one distal top rib (125a) disposed eccentrically from the axis (1000) on the proximal bottom surface (113), and proximal shaft rupture means (117) comprising at least one proximal shaft rib (125b) disposed eccentrically from the axis (1000) on the distal end plate (107b). Each said at least one distal top rib (125a) is connected to a corresponding at least one proximal shaft rib (125b), said ribs (125a, 125b) being connected at a contact area (118), and wherein said distal top rupture means (116) is configured to detach from the proximal shaft rupture means (117) due to compression failure when the distal plunger top (105) is pushed into a distal end (110) of the barrel (102). A syringe is also provided.

9. 发明授权

US11497860B2 Ultra-low waste disposable safety syringe for low dose injections 有权
公开(公告)号：US11497860B2
公开(公告)日：2022-11-15
申请号：US16908608
申请日：2020-06-22
申请人： Sharps Technology, Inc.
发明人： Barry B. Berler
IPC分类号： A61M5/32 , A61M5/50 , A61M5/31
摘要： A needle and syringe system, wherein a needle head is attached to a syringe assembly. The syringe assembly includes a syringe barrel and a plunger rod with a plunger head. A needle base is affixed to the syringe barrel. A tubular cavity is formed in the needle base and a post extends through the tubular cavity. A needle extends through the post. A spacer is provided. The spacer is displaced into the tubular cavity within the needle base as the plunger head is advanced within the syringe barrel. A protective cover is disposed about the needle base. The spacer moves the protective cover between a first position and a second position as the spacer is displaced into the tubular cavity. As the protective cover moves between positions, the protective cover surrounds the needle and prevents the needle from causing any inadvertent needle stick injuries.

10. 发明授权

US11491273B2 Adhesive and peripheral systems and methods for medical devices 有权
公开(公告)号：US11491273B2
公开(公告)日：2022-11-08
申请号：US16192213
申请日：2018-11-15
申请人： DEKA Products Limited Partnership
发明人： Larry B. Gray
IPC分类号： A61M5/142 , F04B43/02 , A61M5/168 , G05D7/06 , F04B43/09 , F04B7/00 , A61M5/32 , B23P15/00 , A61M5/145 , G01F22/00 , A61M5/14 , F04B43/12 , A61M5/172 , G08C17/02 , H04B7/26 , G05B23/02 , A61M5/158 , A61B5/00 , A61M5/50 , A61M5/162 , A61M5/36 , A61B5/155 , A61J1/20
摘要： A system is disclosed. The system includes a reservoir for containing a fluidic medium, the reservoir including a front surface, a resilient cylindrical flexure portion connected to the front surface, the resilient cylindrical flexure portion comprising an accordion-like structure that is able to expand and contract to change an interior volume within the resilient cylindrical flexure portion, a central passageway within the resilient cylindrical flexure, and a collection chamber connected to the central passageway. Also, a system including a reservoir, a plunger head located within the reservoir, a plunger arm connected to the plunger head, a driving shaft connected to the plunger arm, and a motor connected to the driving shaft, the motor controllable to move the drive shaft in a first motion and a second motion so as to move the advance plunger head and retract the plunger head within the reservoir.

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