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1. 发明授权

US11261378B2 Polymerizable compound and optically anisotropic object 有权
公开(公告)号：US11261378B2
公开(公告)日：2022-03-01
申请号：US15539666
申请日：2015-12-17
申请人： DIC CORPORATION
发明人： Masahiro Horiguchi , Sayaka Nose , Akihiro Koiso
IPC分类号： C09K19/54 , C07C69/753 , C07C69/76 , C07D333/22 , C07D339/06 , C07D339/08 , C07D407/12 , C07D409/12 , C07C323/21 , C07D413/12 , C07D417/04 , C07D417/06 , C07D249/06 , C07C327/48 , C07C251/24 , C07D207/452 , C07C251/86 , C07C251/88 , C07D209/12 , C07D277/82 , C07D513/04 , C08F20/10 , G02B5/30 , C07C69/94 , C07C69/75 , C09K19/34 , C07D409/14 , C07D305/06 , C07C251/78 , C07D403/04 , C07D209/40 , C07D303/48 , C09K19/32 , C07D495/04 , C07C69/757 , C07C245/08 , C07D333/36 , C07D307/66 , C07D403/12 , C07D417/12 , C07D265/16 , C07D249/04 , C07D213/74 , C07C251/18 , C07D409/06 , C07D333/76 , C07D277/64 , C07D209/88 , C09K19/38 , G02F1/13363 , C09K19/04 , C08F220/30
摘要： The present invention aims to provide a polymerizable compound that has high storage stability without causing crystal precipitation when added to a polymerizable composition and to provide a polymerizable composition containing the polymerizable compound. A polymer film produced by polymerization of the polymerizable composition has a low haze, high thickness uniformity, low occurrence of nonuniform orientation, high surface hardness, high adhesiveness, and good appearances and fewer orientation defects even after ultraviolet irradiation. The present invention also aims to provide a polymer produced by polymerization of the polymerizable composition and an optically anisotropic body produced from the polymer.

2. 发明授权

US10421710B2 Substituted phenethylamines with serotoninergic and/or norepinephrinergic activity 有权
公开(公告)号：US10421710B2
公开(公告)日：2019-09-24
申请号：US14559520
申请日：2014-12-03
申请人： Auspex Pharmaceuticals, Inc.
发明人： Thomas G. Gant , Sepehr Sarshar , Soon Hyung Woo
IPC分类号： C07C211/64 , C07B59/00 , C07C215/64 , C07C217/74 , C07D265/16
摘要： Chemical syntheses and medical uses of novel inhibitors of the uptake of monoamine neurotransmitters and pharmaceutically acceptable salts and prodrugs thereof, for the treatment and/or management of psychotropic disorders, anxiety disorder, generalized anxiety disorder, depression, post-traumatic stress disorder, obsessive-compulsive disorder, panic disorder, hot flashes, senile dementia, migraine, hepatopulmonary syndrome, chronic pain, nociceptive pain, neuropathic pain, painful diabetic retinopathy, bipolar depression, obstructive sleep apnea, psychiatric disorders, premenstrual dysphoric disorder, social phobia, social anxiety disorder, urinary incontinence, anorexia, bulimia nervosa, obesity, ischemia, head injury, calcium overload in brain cells, drug dependence, attention deficit hyperactivity disorder, fibromyalgia, irritable bowel syndrome, and/or premature ejaculation are described.

3. 发明授权

US10106653B2 Continuous high shear reactor melt processing methods to synthesize heterocyclic monomer and prepolymer alloys and compositions thereof 有权
公开(公告)号：US10106653B2
公开(公告)日：2018-10-23
申请号：US15368533
申请日：2016-12-02
申请人： Andrew S. Frazee , Jeffrey S. Wiggins
发明人： Andrew S. Frazee , Jeffrey S. Wiggins
IPC分类号： C08G73/10 , C07D265/16
摘要： The invention provides novel methods of synthesizing new monofunctional and/or multifunctional heterocyclic monomer and prepolymer alloys via a continuous solvent-free, or alternatively in-solvent, one-step high shear reactor methodology designed to eliminate the need for post-processing purification and react monomer to predictable conversions, as well as the synthesis of related compositions. Additionally, the invention allows the dispersion of reinforcements and additives while synthesizing heterocyclic monomers and formulating heterocyclic prepolymer alloys.

4. 发明授权

US10106511B2 Continuous high shear reactor melt processing methods to synthesize heterocyclic monomers and compositions thereof 有权
公开(公告)号：US10106511B2
公开(公告)日：2018-10-23
申请号：US15367075
申请日：2016-12-01
申请人： Andrew S. Frazee , Jeffrey S. Wiggins
发明人： Andrew S. Frazee , Jeffrey S. Wiggins
IPC分类号： C07D265/16 , C07D207/404 , C08G73/10
摘要： The invention provides novel methods of synthesizing new monofunctional and/or multifunctional heterocyclic monomers and the formulation of new alloys of said monomers from base reactants via a continuous solvent-free, or alternatively in-solvent, one-step high shear reactor methodology designed to reduce the minor isomer formation and to eliminate the need for post-processing purification, as well as the ability to disperse reinforcements and additives while synthesizing such heterocyclic monomers and monomer alloys created and to the synthesis of related compositions.

5. 发明授权

US10023698B2 Curable benzoxazine compositions with improved thermal stability 有权
公开(公告)号：US10023698B2
公开(公告)日：2018-07-17
申请号：US15515162
申请日：2015-12-08
申请人： 3M INNOVATIVE PROPERTIES COMPANY
发明人： Ilya Gorodisher , Gregory P. Sorenson , Mark McCormick , Katri M. Huikko , Robert J. Webb
IPC分类号： C07D265/16 , C08G73/02
摘要： A curable benzoxazine composition is described wherein the benzoxazine is derived from an aryl amine having a b.p.>200° C. The curable compositions are more thermally stable and have reduced weight loss and by-products upon cure.

6. 发明授权

US09714322B2 Trifunctional benzoxazine 有权
公开(公告)号：US09714322B2
公开(公告)日：2017-07-25
申请号：US14980407
申请日：2015-12-28
申请人： Cytec Industries Inc.
发明人： Ram B Gupta , Paul Mark Cross
IPC分类号： C08G63/02 , C08G73/02 , C07D265/16 , C08J5/24 , C08L79/02
CPC分类号： C08G73/0233 , C07D265/16 , C08J5/24 , C08J2379/02 , C08L79/02
摘要： A meta-substituted trifunctional benzoxazine monomer and compositions containing the same, wherein the trifunctional benzoxazine monomer is represented by the following structure:

7. 发明申请

US20160297779A1 MODIFIED OXAZINE RESIN AND USE OF A COMPOSITION COMPRISING THE SAME 审中-公开
标题翻译：改性氧化树脂及其组合物的使用
公开(公告)号：US20160297779A1
公开(公告)日：2016-10-13
申请号：US15072416
申请日：2016-03-17
申请人： Elite Material Co., Ltd.
发明人： Chen-Yu HSIEH , Hui-Ting SHIH
IPC分类号： C07D265/12 , C08F222/08 , C08G73/06 , H05K1/03 , C08K5/5399 , C08K5/03 , C08K5/5313 , C08J5/24 , C07D265/16 , C08K3/36
CPC分类号： C07D265/12 , C07D265/16 , C08F222/08 , C08G73/06 , C08J5/24 , C08J2379/04 , C08L35/06 , H05K1/0373
摘要： The present disclosure is to provide a modified oxazine compound and use of a composition comprising the same.
摘要翻译：本公开内容旨在提供修饰的恶嗪化合物和包含其的组合物的用途。

8. 发明申请

US20080234257A1 SUBSTITUTED PHENETHYLAMINES WITH SEROTONINERGIC AND/OR NOREPINEPHRINERGIC ACTIVITY 审中-公开
标题翻译：具有丝氨酸和/或非诺贝宁活性的取代的苯乙烯
公开(公告)号：US20080234257A1
公开(公告)日：2008-09-25
申请号：US12048012
申请日：2008-03-13
申请人： Thomas G. Gant , Sepehr Sarshar , Soon Hyung Woo
发明人： Thomas G. Gant , Sepehr Sarshar , Soon Hyung Woo
IPC分类号： A61K31/537 , C07C211/27 , A61K31/14 , C07K14/705 , A61K31/137 , C07D265/16
摘要： Chemical syntheses and medical uses of novel inhibitors of the uptake of monoamine neurotransmitters and pharmaceutically acceptable salts and prodrugs thereof, for the treatment and/or management of psychotropic disorders, anxiety disorder, generalized anxiety disorder, depression, post-traumatic stress disorder, obsessive-compulsive disorder, panic disorder, hot flashes, senile dementia, migraine, hepatopulmonary syndrome, chronic pain, nociceptive pain, neuropathic pain, painful diabetic retinopathy, bipolar depression, obstructive sleep apnea, psychiatric disorders, premenstrual dysphoric disorder, social phobia, social anxiety disorder, urinary incontinence, anorexia, bulimia nervosa, obesity, ischemia, head injury, calcium overload in brain cells, drug dependence, attention deficit hyperactivity disorder, fibromyalgia, irritable bowel syndrome, and/or premature ejaculation are described.
摘要翻译：用于治疗和/或治疗精神病症，焦虑障碍，广泛性焦虑症，抑郁症，创伤后应激障碍，强迫症的单胺神经递质及其药学上可接受的盐和前药的新型抑制剂的化学合成和医学用途，强迫症，恐慌症，热潮红，老年痴呆，偏头痛，肝肺综合征，慢性疼痛，伤害性疼痛，神经性疼痛，疼痛性糖尿病性视网膜病变，双相抑郁症，阻塞性睡眠呼吸暂停，精神疾病，经前焦虑症，社交恐惧症，社交焦虑症，尿失禁，厌食症，神经性贪食症，肥胖症，缺血，头部损伤，脑细胞中的钙超载，药物依赖，注意缺陷多动障碍，纤维肌痛，肠易激综合征和/或早泄。

9. 发明授权

US6160079A Activated arylamine-based polybenzoxazines 失效
标题翻译：活性芳胺基聚苯并恶嗪
公开(公告)号：US6160079A
公开(公告)日：2000-12-12
申请号：US291466
申请日：1999-04-14
申请人： Hatsuo Ishida , Daniel Sanders
发明人： Hatsuo Ishida , Daniel Sanders
IPC分类号： C07D265/16 , C08G14/06 , C08G61/12 , C08G8/04
CPC分类号： C08G61/12 , C07D265/16 , C08G14/06
摘要： Arylamines with electron donating groups such as alkyl and alkoxy groups in the meta position on the aromatic ring change the polymerization temperature of the benzoxazine prepared therefrom and offer an opportunity for an additional crosslinking site (the para position on the aromatic amine can couple to a Mannich base generated by the opening of the oxazine ring of the benzoxazine or a methylene bridge generated by a degradation reaction). Naphthenic amines with an alkyl or alkoxy substituent on the 5.sup.th through the 8.sup.th carbon atom on the naphthalene ring can function similarly. The polymers for benzoxazines prepared from at least 10% substituted aromatic or naphthenic amines are useful due to low polymerization temperatures and higher Tg (glass transition temperature).
摘要翻译：在芳环上的间位的具有供体基团如烷基和烷氧基的芳胺改变由其制备的苯并恶嗪的聚合温度，并提供另外的交联位点的机会（芳胺上的对位可以连接到曼尼希通过苯并恶嗪的恶嗪环的开放产生的碱或由降解反应产生的亚甲基桥）。在萘环上的第5个到第8个碳原子上具有烷基或烷氧基取代基的环烷胺类似地起作用。由至少10％取代的芳族或环烷胺制备的苯并恶嗪的聚合物是有用的，因为低聚合温度和较高的Tg（玻璃化转变温度）。

10. 发明授权

US5925789A Asymmetric synthesis of benzoxazinones 失效
公开(公告)号：US5925789A
公开(公告)日：1999-07-20
申请号：US55480
申请日：1998-04-06
申请人： Michael E. Pierce , Cheng Y. Chen , Anusuya Choudhury , Lilian A. Radesca , Lushi Tan , Dalian Zhao
发明人： Michael E. Pierce , Cheng Y. Chen , Anusuya Choudhury , Lilian A. Radesca , Lushi Tan , Dalian Zhao
IPC分类号： C07D265/16 , A61P31/18 , A61P37/04 , C07C213/00 , C07C213/02 , C07C215/68 , C07C215/70 , C07C217/58 , C07C221/00 , C07C225/22 , C07D265/18 , C07C209/18
CPC分类号： C07D265/18 , C07C213/00 , C07C213/02 , C07C221/00 , C07C2101/02
摘要： The present invention provides novel methods for the asymmetric synthesis of (S)-6-chloro-4-cyclopropylethynyl-4-trifluoromethyl-1,4-dihydro-2H-3,1-benzoxazin-2-one of formula (VI-i) ##STR1## which is useful as a human immunodeficiency virus (HIV) reverse transcriptase inhibitor.

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