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1. 发明授权

US5914124A Alginate fibre, process for the preparation thereof and use 失效
标题翻译：海藻酸纤维，其制备方法和用途
公开(公告)号：US5914124A
公开(公告)日：1999-06-22
申请号：US765748
申请日：1997-05-30
申请人： Peter M. J. Mahoney , David Pritchard , Anne Elizabeth Howells , Bryan Griffiths
发明人： Peter M. J. Mahoney , David Pritchard , Anne Elizabeth Howells , Bryan Griffiths
IPC分类号： A61K9/70 , A61L15/28 , A61L15/38 , A61L15/44 , A61L15/46 , A61L15/64 , D01F9/04 , D06M11/00 , D06M11/07 , D06M11/13 , D06M11/76 , D06M15/15 , D06M101/04 , A61F13/00
CPC分类号： D01F9/04 , A61K9/70 , A61L15/28 , A61L15/38 , A61L15/44 , A61L15/46 , Y10S424/13
摘要： Alginate fibres comprising at least one medicament incorporated into the structure thereof, the medicament being present at a level of at least 10% by weight, based on the weight of the alginate fibre with no incorporated medicament.
摘要翻译： PCT No.PCT / EP95 / 02773 371日期1997年5月30日 102（e）日期1997年5月30日PCT提交1995年7月14日PCT公布。公开号WO96 / 02284 日期1996年2月1日包含至少一种掺入其结构的药物的海藻酸纤维，所述药物的存在量为至少10重量％，基于没有掺入药物的藻酸盐纤维的重量。

2. 发明授权

US5622707A Composite membranes for the guided regeneration of tissues 失效
标题翻译：复合膜用于组织的引导再生
公开(公告)号：US5622707A
公开(公告)日：1997-04-22
申请号：US992697
申请日：1992-12-18
申请人： Franco Dorigatti , Lanfranco Callegaro , Aurelio Romeo
发明人： Franco Dorigatti , Lanfranco Callegaro , Aurelio Romeo
IPC分类号： A61L15/22 , A61F2/10 , A61L15/07 , A61L27/48 , A61L31/00 , A61L31/04 , A61L31/12 , A61L31/14 , D01F9/00 , D01F9/04 , D03D15/00 , D04H1/42 , D04H13/00 , D06M15/03 , A61K9/70 , A61K31/00
CPC分类号： A61L31/148 , A61F2/105 , A61L27/48 , A61L31/041 , A61L31/042 , A61L31/129 , Y10T428/24124 , Y10T442/172
摘要： Biomaterials are disclosed comprised of biodegradable, biocompatible, and bioabsorbable composite membranes for use in surgery for the guided regeneration of tissues. The composite membranes are comprised of threads embedded in a matrix, wherein both the matrix and the threads can be comprised of esters of hyaluronic acid, used singly or in combination, or esters of hyaluronic acid in combination with esters of alginic acid or other polymers.
摘要翻译：公开的生物材料包括用于组织引导再生的手术中的可生物降解的，生物相容的和生物可吸收的复合膜。复合膜由嵌入基质中的线组成，其中基质和丝线都可以由透明质酸单独或组合使用的酯，或透明质酸的酯与藻酸或其它聚合物的酯组合而成。

3. 发明授权

US5474781A Water soluble algin fibers and production thereof 失效
标题翻译：水溶性藻酸纤维及其生产
公开(公告)号：US5474781A
公开(公告)日：1995-12-12
申请号：US643936
申请日：1991-01-22
申请人： Yoshinari Kobayashi , Hiroshi Kamishima , Satoshi Fukuoka , Hideki Obika , Tsutomu Asaoka , Keishi Tenma
发明人： Yoshinari Kobayashi , Hiroshi Kamishima , Satoshi Fukuoka , Hideki Obika , Tsutomu Asaoka , Keishi Tenma
IPC分类号： A61L15/28 , A61L15/44 , D01D5/06 , D01F1/10 , D01F9/04 , A61K9/00
CPC分类号： A61L15/28 , A61L15/44 , D01F1/10 , D01F1/103 , D01F9/04 , A61L2300/406
摘要： There is disclosed water soluble algin fibers and such fibers which have antibiotics immobilized thereto. The water soluble algin fibers are produced by extruding an aqueous dope which contains water soluble algin therein into a large quantity of a hydrophilic organic nonsolvent exemplified by acetone. The water soluble algin fibers which have antibiotics immobilized thereto are produced in the same manner by using a dope containing antibiotics.
摘要翻译：公开了水溶性藻酸纤维和固定有抗生素的纤维。水溶性藻酸纤维是通过将包含水溶性藻糖的水性涂料挤出到大量例如丙酮的亲水性有机非溶剂中而制成的。通过使用含有抗生素的涂料，以相同的方式生产固定有抗生素的水溶性藻酸纤维。

4. 发明授权

US5080657A Alginic 失效
标题翻译：海藻
公开(公告)号：US5080657A
公开(公告)日：1992-01-14
申请号：US445186
申请日：1989-12-01
申请人： Hae B. Lee , Byung C. Shin
发明人： Hae B. Lee , Byung C. Shin
IPC分类号： A61F13/00 , A61F13/15 , A61L15/60 , D01F9/04
CPC分类号： A61F13/53 , A61L15/60 , D01F9/04 , A61F13/15252 , A61F2013/00463 , A61F2013/530613 , A61F2013/53062 , A61F2013/530708 , A61F2013/530795 , Y10T442/696
摘要： This invention is a catamenial pad or a tampon or a diaper which contains carboxymethylalginate (CMA) and alginic acid salt. The pad or diaper can be made from fibers composed of CMA alone or a mixture of CMA and alginic acid salt. CMA may be prepared by reacting chloroacetic acid, NaOH, and an alginic acid salt dispersed in a liquid aliphatic alcohol. More in detail, CMA can be prepared by a reaction in which sodium alginate is dispersed into ethanol, reacted with NaOH and chloroacetic acid at 40.degree.-50.degree.C. with agitation. The CMA can be spun into fibers and then it can be prepared into non-woven fabric. The fabric pad or diaper can be made into various designs. The fabric or the fiber has high absorbency, water-retentivity, stability, and coagulating ability against blood.
摘要翻译：本发明是含有羧甲基海藻酸盐（CMA）和海藻酸盐的月经垫或棉塞或尿布。衬垫或尿布可以由单独的CMA或CMA和藻酸盐的混合物组成的纤维制成。 CMA可以通过使氯乙酸，NaOH和分散在液体脂族醇中的藻酸盐反应来制备。更详细地，可以通过其中将藻酸钠分散在乙醇中的反应制备CMA，在40℃-50℃下与NaOH和氯乙酸反应。 CMA可以纺成纤维，然后可以制成无纺布。织物垫或尿布可以制成各种设计。织物或纤维对血液具有高吸收性，保水性，稳定性和凝结能力。

5. 发明授权

US4744830A Fibrous binder and a method for the preparation thereof 失效
标题翻译：纤维粘合剂及其制备方法
公开(公告)号：US4744830A
公开(公告)日：1988-05-17
申请号：US935203
申请日：1986-11-26
申请人： Yoshinari Kobayashi , Ryukichi Matsuo
发明人： Yoshinari Kobayashi , Ryukichi Matsuo
IPC分类号： A61L15/28 , A61L15/60 , C08L5/00 , C09J105/04 , D01F9/04 , D04H1/542 , D21H13/10
CPC分类号： D21H5/1227 , A61L15/28 , A61L15/60 , C09J105/04 , D01F9/04 , D21H13/32
摘要： The invention provides a fibrous binder capable of exhibiting a bonding ability in a dry condition for fibers having no self-adhesiveness in paper making but capable of imparting the paper made by use of the same with disintegrability into discrete fibers in a wet condition so that the paper is disposable in water. The fibrous binder is prepared by wet-spinning of an aqueous dope containing a water-soluble salt, e.g. sodium salt, of alginic acid and an alkyleneglycol ester of alginic acid in a specified proportion into a coagulation bath containing a water-soluble salt of certain metals, e.g. calcium, of which the ions are replaceable with the sodium ions of the water-soluble salt of alginic acid to convert the acid into a water-insoluble salt so as to form a water-insoluble gel in a fibrous form of a blend composed of the water-insoluble metal salt of alginic acid and the alkyleneglycol ester of alginic acid.
摘要翻译：本发明提供了一种纤维粘合剂，其能够在干燥条件下对造纸中没有自粘性的纤维表现出粘合能力，但能够在湿润状态下将其使用具有崩解性的纸赋予离散纤维，纸是一次性的在水中。纤维粘合剂通过将含有水溶性盐的水溶液湿法纺丝制备，钠盐，海藻酸和藻酸的亚烷基二醇酯以特定比例加入到含有某些金属的水溶性盐的凝固浴中，钙，其中离子可与藻酸的水溶性盐的钠离子替代，以将酸转化成不溶于水的盐，以形成纤维形式的共混物，其由藻酸的水不溶性金属盐和藻酸的亚烷基二醇酯。

6. 发明授权

US3862290A Method for shaping cell protein 失效
标题翻译：形成细胞蛋白的方法
公开(公告)号：US3862290A
公开(公告)日：1975-01-21
申请号：US30527272
申请日：1972-11-10
申请人： KYOWA HAKKO KOGYO KK
发明人： YAMAMOTO ATSUSHI , TERANISHI HIROSHI , FURUKAWA TADAYASU , MATSUKI TAKASHI
IPC分类号： A23J1/00 , A23J1/18 , A23J3/26 , D01F9/04
CPC分类号： A23J1/008 , A23J1/18 , A23J3/26 , Y10S530/82
摘要： A method for shaping cell protein for use in food processing which involves dissolving or dispersing protein obtained from said cell bodies at a pH which is more alkaline than the isoelectric point of the protein, contacting the resulting solution with a coagulating agent and adjusting the pH of the resulting coagulum.
摘要翻译：一种用于形成用于食品加工的细胞蛋白的方法，其涉及将所述细胞体获得的蛋白质溶解或分散在比蛋白质等电点更碱性的pH下，使所得溶液与凝固剂接触并调节pH 所产生的凝结物。

7. 发明申请

US20210162090A1 COMPOSITE FIBER 有权
公开(公告)号：US20210162090A1
公开(公告)日：2021-06-03
申请号：US16699138
申请日：2019-11-29
申请人： National Central University
发明人： Wei-Wen Hu , Yu-Ting Lin
IPC分类号： A61L15/22 , A61K33/38 , A61K38/18 , A61L15/44 , D01D5/00 , D01F9/04 , D01F6/62 , D01F1/10
摘要： The present invention provides a composite fiber which comprises an alginate fiber, a polymer material, an antibacterial agent, and a plasmid encoding growth factor-gene. The present invention also provides a wound dressing, wherein the wound dressing comprises a composite fiber as described above. The composite fibers prepared according to the present invention are capable of releasing the antibacterial agent and the growth factor gene, not only to reduce microorganism growth, but also to secrete growth factors in a wound site through transfection, thereby promoting wound healing.

8. 发明授权

US09958088B2 Microvalve using surface tension, microfluidic chip comprising same, and method for manufacturing same 有权
公开(公告)号：US09958088B2
公开(公告)日：2018-05-01
申请号：US13988892
申请日：2011-11-23
申请人： Sang Hoon Lee , Edward Kang
发明人： Sang Hoon Lee , Edward Kang
IPC分类号： F16K99/00 , D01D5/00 , D01F6/84 , D01F9/00 , D01F9/04 , G01N35/00
CPC分类号： F16K99/0015 , D01D5/00 , D01F6/84 , D01F9/00 , D01F9/04 , F16K99/0017 , F16K99/0055 , F16K99/0059 , G01N2035/00158 , Y10T29/49412 , Y10T156/1002
摘要： The present disclosure relates to a microvalve using surface tension, a microfluidic chip including same and a method for manufacturing same. More particularly, the present disclosure relates to a microvalve using surface tension, a microfluidic chip including same and a method for manufacturing same, wherein the microvalve can be manufactured through a simple process and the microvalve and a coaxial sample channel are not separated, and thus the microvalve may be easily installed not only in an existing quadrangular channel but also in the coaxial channel so as to control the flow and amount of a microfluid (sample).

9. 发明申请

US20180094369A1 NONWOVEN FABRIC 审中-公开
公开(公告)号：US20180094369A1
公开(公告)日：2018-04-05
申请号：US15720206
申请日：2017-09-29
申请人： ADVANCED MEDICAL SOLUTIONS LIMITED
发明人： David HORRIDGE , Colin BRADFORD
IPC分类号： D04H1/485 , D01F9/04 , A61L15/22 , A61L15/28
CPC分类号： D04H1/485 , A61L15/225 , A61L15/28 , D01F9/04 , D04H1/46 , D04H18/02
摘要： The present invention relates to a bonded nonwoven fabric generally comprising absorbent staple fibres and having bonding stripes of relatively high fibre entanglement density extending along the fabric and into the fabric from at least one face thereof. A method of producing a bonded nonwoven fabric suitable for use as an absorbent layer in a wound dressing is also described.

10. 发明授权

US5980930A Fibres 失效
标题翻译：纤维
公开(公告)号：US5980930A
公开(公告)日：1999-11-09
申请号：US491963
申请日：1995-09-15
申请人： John Charles Fenton , Bryan Griffiths , Peter Michael John Mahoney
发明人： John Charles Fenton , Bryan Griffiths , Peter Michael John Mahoney
IPC分类号： A61F13/00 , A61L15/16 , A61L15/28 , D01F9/04 , D03D15/00 , D06M11/00 , D06M11/11 , D06M101/00 , D06M101/16 , D06M101/30 , D06M101/34 , A61L15/00
CPC分类号： A61F13/00042 , A61L15/28 , D01F9/04 , A61F13/069 , A61F2013/00157 , A61F2013/00225 , A61F2013/00523 , Y10T442/2484 , Y10T442/2525
摘要： Highly absorbent alginate fibers are described which have use in the manufacture of dressings. The fibers and dressings described are highly swellable while also being soluble, rather than just being soluble. This is a considerable advantage for use in environments where high absorption coupled with biodegradability is desired, for example, in wound dressings such as dressings for ulcers or burns.
摘要翻译： PCT No.PCT / GB94 / 00102 Sec。 371 1995年9月15日第 102（e）1995年9月15日PCT PCT 1994年1月19日PCT公布。公开号WO94 / 17227 PCT 日期1994年8月4日描述了用于制造敷料的高吸收性藻酸盐纤维。所描述的纤维和敷料是高度溶胀的，同时也是可溶的，而不仅仅是可溶的。对于需要高吸收性与生物降解性的环境，例如在诸如用于溃疡或烧伤的敷料的伤口敷料中，这是相当大的优点。

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