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1. 发明申请

WO2017093788A1 AN ANTI FISSURE HERBAL COMPOSITION FOR TARGETING FISSURE AND METHOD OF SYNTHESIZING THE SAME 审中-公开
标题翻译：一种用于定位裂缝的抗裂草本组合物及其合成方法
公开(公告)号：WO2017093788A1
公开(公告)日：2017-06-08
申请号：PCT/IB2015/059306
申请日：2015-12-03
申请人： MORADI, Asghar
发明人： MORADI, Asghar
IPC分类号： A61K36/00
CPC分类号： A61K36/63 , A61K9/0031 , A61K9/06 , A61K9/12 , A61K36/185 , A61K36/23 , A61K36/28 , A61K36/47 , A61K36/50 , A61K36/55 , A61K36/752 , A61K36/88 , A61K36/886 , A61K36/8962 , Y02A50/473 , Y02A50/481 , A61K2300/00
摘要： The embodiments herein disclose method and composition for the treatment of external fissures, internal fissures, constipation and tissue crack around anus. The herbal spray for external anal fissure comprises 32000mg of Matricaria recutita extract, l000mg of Crocus sativus extract, 7000mg of Aloe vera extract and 10000mg of Althaea officinalis flower extract. The herbal spray for internal anal fissure comprises 40000mg of Matricaria recutita flower extract, 25000mg Allium porrum shoot extract, 25000mg Apium graveolens stalk extract, 15000mg Fumaria officinalis shoot extract and 5000mg honey. The topical anti constipation oil mixture comprises 30000mg Sesamum indicum and 20000mg castor oil. The anus anti-crack ointment comprises 15000mg sesame oil, 8500mg olive oil and 1500mg spermaceti . The external spray treats clots and bleeding. The internal herbal mixture stops bleeding, heals internal swelling, eases defecation and recovers rectum. The topical oil and anti-crack ointment softens the skin and helps the recovery of cracks inside the anus.
摘要翻译：这里的实施例公开了用于治疗肛门周围的外部裂缝，内部裂缝，便秘和组织裂缝的方法和组合物。用于外肛裂的草药喷雾剂包括32000mg的母菊提取物，1000mg的番红花提取物，7000mg的芦荟提取物和10000mg的Althaea officinalis >花提取物。用于内部肛裂的草药喷雾剂包括40000mg的Matricaria recutita花提取物，25000mg的葱属芽提取物，25000mg的Apium graveolens茎提取物，15000mg的枸杞子提取物，我> Fumaria officinalis拍摄提取物和5000毫克蜂蜜。外用抗便秘油混合物包含30000mg印度楝和20000mg蓖麻油。肛门防裂软膏包含15000mg芝麻油，8500mg橄榄油和1500mg鲸蜡。外部喷雾处理凝块和出血。内部草药混合物止血，治愈内部肿胀，缓解排便并恢复直肠。局部用油和抗裂软膏可软化皮肤，帮助恢复肛门内的裂缝。

2. 发明申请

WO2017082524A1 삼채 추출물을 유효성분으로 함유하는 종양 억제용 약학적 조성물 审中-公开
标题翻译：含有管状提取物作为活性成分的肿瘤抑制药物组合物
公开(公告)号：WO2017082524A1
公开(公告)日：2017-05-18
申请号：PCT/KR2016/009310
申请日：2016-08-23
申请人： 대한민국(농촌진흥청장)
发明人： 이성현 , 한현순 , 최정숙 , 김정봉 , 장환희
IPC分类号： A61K36/8962 , A23L1/30
CPC分类号： A61K36/8962
摘要： 본 발명은 삼채( Allium hookeri ) 추출물을 유효성분으로 함유하는 종양 억제용 약학적 조성물에 관한 것으로, 삼채의 잎과 뿌리를 각각 70% 발효주정으로 추출하여 삼채 추출물을 수득하고, 이를 닭 종양 세포에 처리한 결과, 종양세포의 성장이 저해되고, 배양 시간이 길어질수록 삼채 추출물의 항종양 효과가 상승하며, 삼채 잎이 뿌리보다 종양세포에 증식 억제가 뛰어남을 확인함으로써, 본 발명의 삼채 추출물은 암 예방 및 치료용 약학적 조성물로 유용하게 사용될 수 있다.
摘要翻译：
本发明为三（宽叶的）涉及含有作为活性成分对肿瘤抑制药物组合物中的提取物，三的叶和根的70％，各发酵后用乙醇提取，得到三种提取物，并且在鸡的肿瘤细胞处理它们，肿瘤细胞的生长被抑制，和较长的温育时间增加了三种提取物的抗肿瘤效果，三个叶肿瘤细胞比根通过证实抑制增殖是优异的，本发明的管状提取物可以有效地用作癌症预防和治疗的药物组合物。

3. 发明申请

WO2017000449A1 一种治疗消化系统溃疡的中药及其制备方法审中-公开
公开(公告)号：WO2017000449A1
公开(公告)日：2017-01-05
申请号：PCT/CN2015/093344
申请日：2015-10-30
申请人：济南正骐生物科技有限公司
发明人：张丽 , 丁敏 , 王桂珍
IPC分类号： A61K36/899 , A61K36/8962 , A61K36/8888 , A61K36/752 , A61K36/74 , A61K36/66 , A61K36/58 , A61K36/535 , A61K35/64 , A61K35/56 , A61P1/04
CPC分类号： A61K35/56 , A61K35/63 , A61K36/535 , A61K36/58 , A61K36/66 , A61K36/74 , A61K36/752 , A61K36/8888 , A61K36/8962 , A61K36/899
摘要：治疗消化系统溃疡的中药及其制备方法，该中药使用瓜蒌、苏梗、陈皮各30-40重量份，法半夏、延胡索、竹茹各25-35重量份，瓦楞子、白花蛇舌草、海螵蛸、薤白各20-25重量份，地龙、山豆根、川楝子各10-15重量份，儿茶5-10重量份制成。

4. 发明申请

WO2016065609A1 ANTI-ADHERENT BOTANICAL COMPOSITIONS 审中-公开
标题翻译：抗附着的植物组合物
公开(公告)号：WO2016065609A1
公开(公告)日：2016-05-06
申请号：PCT/CN2014/090013
申请日：2014-10-31
申请人： KIMBERLY-CLARK WORLDWIDE, INC. , HE, Aimin
发明人： HE, Aimin , ENGELBRECHT, Kathleen C. , KOENIG, David W. , VANDEN HEUVEL, Amy L. , CHAUDHARY, Vinod , WENZEL, Scott W. , BHATT, Divesh , HUANG, Yang
IPC分类号： A61K8/97 , A61K36/00 , A01N65/00
CPC分类号： A01N65/00 , A01N25/08 , A01N31/16 , A01N43/32 , A01N45/00 , A01N65/08 , A01N65/20 , A01N65/24 , A01N65/30 , A01N65/40 , A61K8/0208 , A61K8/347 , A61K8/498 , A61K8/97 , A61K36/16 , A61K36/48 , A61K36/481 , A61K36/482 , A61K36/708 , A61K36/77 , A61K36/8962 , A61Q17/00
摘要： A composition for inhibiting the attachment of microbes to an animate or inanimate surface is disclosed. The composition includes a carrier and an effective amount of an anti-adherent agent. The anti-adherent agents include botanical agents such as Soybean extract, Horse chestnut extract, Gypenoside, Resveratrol, Astragalus extract, Rhubarb rootextract, Allium cepaextract, Cassia seedextract, Ginkgo bilobaextract, and Silymarin, and combinations thereof. The efficacy of the botanical agents is microbe and surface dependent. Various delivery vehicles, including a wipe, may be used to deliver the composition to the surface.
摘要翻译：公开了一种用于抑制微生物附着于生物或无生命表面的组合物。该组合物包括载体和有效量的抗粘连剂。抗粘连剂包括大豆提取物，栗子提取物，木糖苷，白藜芦醇，黄芪提取物，大黄提取物，洋葱提取物，决明子提取物，银杏叶提取物和水飞蓟素等植物药剂及其组合。植物药剂的功效是微生物和表面依赖性。包括擦拭物在内的各种输送车辆可用于将组合物输送到表面。

5. 发明申请

WO2015184311A3 METHOD OF FEEDING AN ANIMAL 审中-公开
标题翻译：饲喂动物的方法
公开(公告)号：WO2015184311A3
公开(公告)日：2016-01-21
申请号：PCT/US2015033267
申请日：2015-05-29
申请人： CARGILL INC
发明人： HILBERT MAXIME , VAN DE LINDE IRENE , LECHEVESTRIER YANNICK , KOEDIJK ROLAND MICHIEL
CPC分类号： A23K50/60 , A23K10/30 , A23K20/111 , A23K20/174 , A23K50/30 , A23K50/70 , A23K50/75 , A61K9/0056 , A61K31/355 , A61K36/53 , A61K36/87 , A61K36/8962 , A61K2300/00
摘要： Disclosed is a method of feeding an animal as a part of its feed ration a composition having vitamin E and a polyphenol source. The animals can include an avian or porcine animal.
摘要翻译：公开了一种将动物作为其饲料定量的一部分喂养具有维生素E和多酚源的组合物的方法。动物可以包括禽类或猪类动物。

6. 发明申请

WO2015184311A2 METHOD OF FEEDING AN ANIMAL 审中-公开
标题翻译：饲喂动物的方法
公开(公告)号：WO2015184311A2
公开(公告)日：2015-12-03
申请号：PCT/US2015/033267
申请日：2015-05-29
申请人： CARGILL, INCORPORATED
发明人： HILBERT, Maxime , VAN DE LINDE, Irene , LECHEVESTRIER, Yannick , KOEDIJK, Roland Michiel
IPC分类号： A23K1/16
CPC分类号： A23K50/60 , A23K10/30 , A23K20/111 , A23K20/174 , A23K50/30 , A23K50/70 , A23K50/75 , A61K9/0056 , A61K31/355 , A61K36/53 , A61K36/87 , A61K36/8962 , A61K2300/00
摘要： Disclosed is a method of feeding an animal as a part of its feed ration a composition having vitamin E and a polyphenol source. The animals can include an avian or porcine animal.
摘要翻译：公开了一种将动物作为其饲料定量的一部分喂养具有维生素E和多酚源的组合物的方法。动物可以包括禽类或猪类动物。

7. 发明申请

WO2015182799A1 지구병 및 가구자를 포함하는 피부 질환 개선용 조성물 审中-公开
标题翻译：用于改善包含HOVENIA DULCIS和SEMEN ALLII TUBEROSI的皮肤疾病的组合物
公开(公告)号：WO2015182799A1
公开(公告)日：2015-12-03
申请号：PCT/KR2014/004780
申请日：2014-05-27
申请人： 윤종성
发明人： 윤종성
IPC分类号： A61K36/8962 , A61K36/72 , A61K8/97 , A61P17/00 , A61Q19/00
CPC分类号： A61K8/97 , A61K36/076 , A61K36/232 , A61K36/481 , A61K36/72 , A61K36/8962 , A61Q19/00 , A61K2300/00
摘要： 본 발명은 피부 질환을 개선할 수 있는 조성물에 관한 것으로, 가구자 및 지구병을 건조 중량비로 1 : 0.2 ~ 5의 비율로 포함할 수 있으며 황기, 당귀, 복령, 갈근, 진피 및 감초로 구성되는 군으로부터 선택되는 하나 이상의 약재를 더 포함할 수 있다. 본 발명의 조성물은 오래전부터 식용으로 이용되어 왔던 식물 추출물들로 구성되어 있어 장기간 복용하여도 안전하며, 스테로이드제와 같은 부작용이 없으므로 아토피, 건선, 습진, 각화증, 양진 및 한포진 등과 같은 난치성 피부 질환의 개선을 위해 효과적으로 사용될 수 있다.
摘要翻译：本发明涉及一种能够改善皮肤病的组合物，该组合物含有干重比1:0.2-5的精液和枸杞子，还含有至少一种选自黄芪，天竺葵，茯苓，葛根，柑橘皮和甘草。本发明的组合物由长时间用于食品的植物提取物组成。因此，组合物即使长期使用也是安全的，并且不具有类固醇制剂的副作用。此外，该组合物可以有效地用于改善顽固性皮肤疾病如特应性皮炎，牛皮癣，湿疹，角化病，痒疹和异位性湿疹。

8. 发明申请

WO2014009759A3 IMPROVEMENTS IN OR RELATING TO ALLIUM EXTRACTS 审中-公开
标题翻译：关于茴香提取物的改进或与提取有关的改进
公开(公告)号：WO2014009759A3
公开(公告)日：2014-03-13
申请号：PCT/GB2013051892
申请日：2013-07-15
申请人： LEPTREX LTD
发明人： BENNETT N , RAMSEY EDWARD DALHOUSIE
IPC分类号： A61K36/8962 , A23L27/10 , A61P31/00 , A61P31/04 , A61P31/10 , A61P31/12
CPC分类号： A61K36/8962
摘要： The present invention relates to improvements in or relating to Allium extracts. In particular, it relates to improvements in or relating to extending the therapeutic half- life or duration of Allium extracts. The invention also relates to the synthesis of certain thiosulfinate compounds, especially to the synthesis of methyl allyl thiosulfinate and allyl methyl thiosulfinate, in particular from either methiin or alliin alone or a mixture of both. The invention further relates to the synthesis of methyl allyl thiosulfinate, allyl methyl thiosulfinate, allicin, and methyl methyl thiosulfinate in a mixture with varying molar or mass ratios depending on the reaction conditions, in particular from either methiin or alliin alone or a mixture of both. A high yielding, optimized synthesis of allicin starts from alliin, whereas methyl methyl thiosulfinate is advantageously obtained from methiin. Also provided is a kit comprising methiin in a first container and/or alliin in a second container and an allinase source, in particular garlic powder in a third container. Finally, the invention provides a method of preparing a mixture of methyl allyl thiosulfinate, allyl methyl thiosulfinate, allyl allyl thiosulfinate (allicin) and methyl methyl thiosulfinate from methiin and pieces of an Allium species.
摘要翻译：本发明涉及对葱属提取物或与葱属提取物有关的改进。特别涉及延长葱属提取物的治疗半衰期或持续时间的改进。本发明还涉及合成某些硫代亚磺酸酯化合物，特别是合成甲基烯丙基硫代亚磺酸酯和烯丙基甲基硫代亚磺酸酯，特别是单独使用甲硫氨酸或蒜氨酸甲酯或两者的混合物。本发明进一步涉及根据反应条件在不同摩尔或质量比的混合物中合成甲基烯丙基硫代亚磺酸酯，烯丙基甲基硫代亚磺酸酯，大蒜素和甲基硫代亚磺酸酯，特别是单独使用甲硫氨酸或蒜氨酸或两者的混合物。大蒜素的高产量，优化的合成从蒜氨酸开始，而甲基甲基硫代亚磺酸酯有利地从甲素获得。还提供了一种试剂盒，其包含第一容器中的methiin和/或第二容器中的蒜氨酸和蒜氨酸来源，特别是第三容器中的大蒜粉。最后，本发明提供了一种从甲硫氨酸和一些葱属物种制备甲基烯丙基硫代亚磺酸酯，烯丙基甲基硫代亚磺酸酯，烯丙基烯丙基硫代亚磺酸酯（大蒜素）和甲基硫代亚磺酸酯的混合物的方法。

9. 发明申请

WO2013152055A1 METHOD AND COMPOSITION FOR AMELIORATING THE EFFECTS FOR A SUBJECT EXPOSED TO RADIATION OR OTHER SOURCES OF OXIDATIVE STRESS 审中-公开
标题翻译：影响暴露于辐射或其他氧化应激源的受试者的影响的方法和组合
公开(公告)号：WO2013152055A1
公开(公告)日：2013-10-10
申请号：PCT/US2013/035045
申请日：2013-04-02
申请人： JONES, Jeffrey, A. , AMERISCIENCES, LP
发明人： JONES, Jeffrey, A. , MONTESINOS, Carlos, A.
IPC分类号： A61K31/375 , A61K31/355 , A61K31/4415 , A61K31/714 , A61K31/593 , A61P35/00 , A61P39/06
CPC分类号： A61K36/16 , A23L33/105 , A23L33/12 , A23L33/15 , A61K31/122 , A61K33/34 , A61K36/31 , A61K36/82 , A61K36/8962 , A61K45/06 , A61K2300/00
摘要： Radiation - oxidative exposure treatment compositions comprise a mixture of micronutrient multivitamin and trace elements, a mixture of antioxidants and chemopreventative agents, and optionally a mixture of fatty acids. Micronutrient multivitamin and trace elements mixtures include vitamins A, Bp, Bl, B2, B3, B5, B6, B7, B9, B12, C, D, E and K; inositol; calcium, iodine, magnesium, zinc, selenium, copper, manganese, chromium, molybdenum, potassium, boron and vanadium. Mixtures of non¬ essential antioxidants and chemopreventative agents include bioflavins, alpha lipoic acid, N- acetyl-L-cysteine, lutein, lycopene, astaxanthin, plant sterols, isoflavones, garlic extract, which provides allicin; green tea extract, cruciferous vegetable extract, fruit extracts, ginkgo biloba extract, coenzyme Q-10, and resveratrol. Fatty acid mixtures include eicosapentaenoic acid and docosahexaenoic acid. Methods of treatment of a subject exposed to a radiation source or an oxidative stress with the radiation - oxidative exposure treatment composition include the step of administering to the subject a daily dose of the radiation - oxidative exposure treatment composition such that the life shortening effects induced by the radiation source or the oxidative stress are ameliorated.
摘要翻译：辐射 - 氧化暴露处理组合物包含微量营养素多种维生素和微量元素的混合物，抗氧化剂和化学预防剂的混合物，以及任选的脂肪酸的混合物。微量营养素多种维生素和微量元素混合物包括维生素A，Bp，B1，B2，B3，B5，B6，B7，B9，B12，C，D，E和K; 肌醇; 钙，碘，镁，锌，硒，铜，锰，铬，钼，钾，硼和钒。非必需抗氧化剂和化学预防剂的混合物包括生物黄素，α-硫辛酸，N-乙酰-L-半胱氨酸，叶黄素，番茄红素，虾青素，植物甾醇，异黄酮，提供大蒜素的大蒜提取物; 绿茶提取物，十字花科植物提取物，果实提取物，银杏提取物，辅酶Q-10和白藜芦醇。脂肪酸混合物包括二十碳五烯酸和二十二碳六烯酸。使用辐射 - 氧化暴露处理组合物治疗暴露于辐射源或氧化应激的受试者的方法包括向受试者施用日剂量的辐射 - 氧化暴露处理组合物的步骤，使得由辐射源或氧化应激被改善。

10. 发明申请

WO2013088225A1 WATERBORNE EXTRACT DERIVED FROM A PLANT BULB RICH IN SULPHUR SUBSTANCES CONTAINING SELENIUM AND GLUCOSE AND SUPPLEMENTED WITH COPPER SALTS, HAVING PROPERTIES AGAINST TUMORS, FUNGI AND DERMATITIS, INCLUDING AUTOIMMUNE DERMATITIS 审中-公开
标题翻译：从含有硒和葡萄糖的硫化物质的植物提取物中提取的水提取物，具有针对肿瘤，真菌和真菌的特性，包括自发免疫原性
公开(公告)号：WO2013088225A1
公开(公告)日：2013-06-20
申请号：PCT/IB2012/002697
申请日：2012-12-13
申请人： MARCONE, Guido
发明人： MARCONE, Guido , DE MARTINO, Angelo
IPC分类号： A61K36/00 , A61K36/896 , A61K36/8962
CPC分类号： A61K36/8962 , A61K31/7004 , A61K33/04 , A61K33/34 , A61K45/06 , A61K2236/331 , A61K2300/00
摘要： Compound comprising garlic, preferably Allium sativum, and supplemented with selenium, copper salts and sugars, preferably glucose, said compound having an apoptotic, cytotoxic or cytostatic action against tumor cells.
摘要翻译：化合物包含大蒜，优选洋葱，并补充有硒，铜盐和糖，优选葡萄糖，所述化合物对肿瘤细胞具有凋亡，细胞毒性或细胞抑制作用。

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